"Ciprofloxacin-Akos" is an eye drop with an antibacterial effect. It is an antibacterial agent of the fluoroquinolone group, which is intended for topical use in the ophthalmic field.
Medication form, composition and packaging
Ciprofloxacin-Akos eye drops are produced in the form of a clear greenish-yellow or yellowish solution.
One milliliter contains three milligrams of ciprofloxacin (as hydrochloride). The following substances act as auxiliary substances: disodium s alt of ethylenediaminetetraacetic acid, water for injection, mannitol or mannitol, benzalkonium chloride, acetic glacial acid, sodium acetate trihydrate or anhydrous.
Product form - polyethylene dropper bottles with a volume of five milliliters in cardboard packs.
Features of pharmacology
According to the instructions, "Ciprofloxacin-Akos" is an antimicrobial agent, a fluoroquinolone derivative. Functions bactericidal. It inhibits bacterialDNA gyrase (topoisomerases IV and II, which are responsible for the supercoiling of chromosomal around nuclear RNA, this is required for reading hereditary information), disrupts DNA synthesis, bacterial division and growth, causes obvious morphological changes (including membranes and cell walls) and accelerated destruction of the bacterial cell.
Bactericidal effect against Gram-negative microorganisms during division and rest (because it affects not only DNA gyrase, but also provokes lysis of the cell wall), Gram-positive microorganisms - only in the process of division.
Reduced toxicity to macroorganism cells can be explained by the absence of DNA gyrase in them.
At the same time, against the background of the use of ciprofloxacin, parallel production of resistance to other antibiotics that do not belong to the number of gyrase inhibitors does not occur, which makes the drug highly effective against bacteria resistant, for example, to tetracyclines, cephalosporins, penicillins, aminoglycosides and other antibiotics.
The vast majority of staphylococci that are resistant to methicillin are resistant to ciprofloxacin. The resistance of sensitive pathogens develops very slowly, since, on the one hand, there are almost no persistent microorganisms left after the influence of ciprofloxacin, on the other hand, there are no enzymes in bacterial cells that inactivate it.
Indications and contraindications
"Ciprofloxacin-Akos" is used for:
- subacute andacute conjunctivitis;
- post- and preoperative prevention of ophthalmosurgical infectious complications;
- blepharoconjunctivitis, blepharitis;
- infectious inflammation of the organs of vision after the penetration of foreign objects or injuries;
- keratoconjunctivitis, keratitis;
- maybomite;
- chronic dacryocystitis;
- corneal ulcer of a bacterial nature.
The drug is contraindicated:
- with viral keratitis;
- with individual sensitivity to the composition of the product;
- children under one year old.
Instructions
"Ciprofloxacin-Akos" is used topically, by instilling them into the conjunctival sac. If the patient has an eye infection of moderate to mild severity, one to two drops should be instilled into the affected eye every four hours. If the infection is severe, then instillation is carried out every two hours. The frequency of use is reduced as the condition improves. The treatment course lasts from one to two weeks.
For a bacterial type ulcer
The use of "Ciprofloxacin-Akos" with a bacterial type ulcer: the first day - instilled every quarter of an hour drop by drop for six hours, then every half an hour drop by drop until a night's sleep; on the second day - drop by drop from morning to night with an hour break; from the third day to the fourteenth - every four hours in the eye drop by drop. If the ulcer does not heal, the treatment course can be continued.
Need to close the bottle after each use. Do not touch the eye with the pipette tip.
Side effects
Local reactions from eye drops "Ciprofloxacin-Akos": allergic reactions, burning, itching, nausea, mild hyperemia and soreness of the conjunctiva may occur; rarely - photophobia, eyelid edema, lacrimation, unpleasant taste after instillation in the mouth, feeling of a foreign object in the eyes, decreased visual acuity, the appearance of a crystalline white precipitate in patients with corneal ulcer, the appearance of spots, keratopathy, corneal infiltration, keratitis.
If any of these symptoms occur, discontinue use immediately and consult a doctor.
Special Instructions
As the instructions for use indicate, "Ciprofloxacin-Akos" should be carefully prescribed to patients with cerebral vascular atherosclerosis, seizure syndrome and circulatory defects of the brain.
The drug is used exclusively locally. The drug should not be injected directly into the anterior chamber of the eye or subconjunctival.
The patient must be informed that if conjunctival hyperemia increases or continues for a long time after using the drops, he needs to stop using the remedy and consult a specialist.
Contact lenses
It is not advisable to wear soft contact lenses during medication. If hard lenses are used, then you need to remove them before the procedure and put them back on 15-20 minutes after the administration of the drug.
Impact on patients' ability to control mechanisms anddriving a vehicle: people who, after using "Ciprofloxacin-Akos" for a while, lose their clarity of vision, are prohibited from working with serious machinery, equipment or machines, or driving a car, since clarity of vision is required immediately after the procedure.
Interaction with other drugs
Pharmaceutical interaction is as follows: ciprofloxacin solution is incompatible with such solutions of agents that have a pH value of 3 to 4, chemically or physically unstable. When used simultaneously with other antimicrobial drugs, a synergistic interaction is usually noted (metronidazole, clindamycin, aminoglycosides, beta-lactam antibiotics).
In the instructions for use for drops "Ciprofloxacin-Akos" no analogues are indicated. Check them out below.
Analogues
Drops have the following analogues:
Ear and eye drops "Ciprofloxacin-Solofarm" in the form of an almost transparent or transparent, slightly colored liquid
Designed for local use: subacute and acute conjunctivitis, meibomitis, blepharoconjunctivitis, keratitis, chronic dacryocystitis, blepharitis, keratoconjunctivitis, bacterial corneal ulcers. Infectious inflammation of the eyes after the penetration of foreign objects and injuries. Prevention before surgery in ophthalmic surgery.
Instill with topical application 1-2 drops into the affected eye, into the lower conjunctival sac every 1-4 hours. As soon as the condition improves, you canincrease the intervals between injections.
Drops "Rocip" eye transparent, yellow or light yellow
It is used in the treatment of infections of the anterior segment and appendages of the apple of the eye, provoked by bacteria susceptible to ciprofloxacin, corneal ulcers in newborns (up to 27 days from birth), infants and toddlers (from 28 days to 23 months), older children (2-11 years old), teenagers (12-18 years old), adults.
In the implementation of treatment with ciprofloxacin, one should take into account the recommendations that are set out in the official instructions for the use of antibacterial agents.
For corneal ulcers, the medicine should be instilled with such intervals between procedures (including at night): on the first day, every 15 minutes, two drops for the first six hours, then every half hour, two drops for the rest of the time days. On the second day of treatment - every hour, two drops. From 2 to 14 days of therapy - every four hours, two drops. If it is necessary to continue treatment for more than two weeks, the dosage regimen should be selected by the attending physician.
If the patient has a disease of the anterior segment of the eyeball, the remedy should be instilled according to the following scheme: one or two drops in the inflamed eye (or both) four times a day.
For serious infections in the first two days, the dosing regimen may include administering the drug every two hours, one or two drops while awake.
The duration of treatment with the remedy for the indicated indications should not beover three weeks.
The dosing regimen for treating children older than one year is the same as for adult patients.
After using the remedy to reduce the likelihood of developing unwanted systemic reactions, it is advisable to lightly press your finger on the inner corner of the eye of the projection of the lacrimal sacs for one to two minutes after the procedure.
Tsiprolet drops
Eye drops are an aqueous solution for topical ophthalmic use. The drug is an antimicrobial drug among fluoroquinolones, it has a bactericidal effect against most gram-positive and gram-negative bacteria, is used to get rid of bacterial pathologies of the organs of vision (keratitis, conjunctivitis), including those provoked by microorganisms that are resistant to other groups of antibiotics.
Tsiprolet eye drops are used to treat bacterial inflammation of the organs of vision and their appendages caused by sensitive bacteria:
- subacute and acute conjunctivitis;
- corneal ulcer of bacterial type;
- keratoconjunctivitis and bacterial keratitis;
- chronic meibomites;
- chronic dacryocystitis;
- keratoblepharitis and blepharitis.
The drug is prescribed for the prevention of bacterial complications after surgery in eye surgery, as well as after trauma. Eye drops "Tsiprolet" are used only as directed by a specialist,the duration of treatment and dosage regimen are determined by the doctor. In the treatment of an inflammatory process of moderate or mild severity, 1-2 drops are dripped every four hours (up to 6 times a day), reducing the multiplicity as the symptoms subside. In severe inflammation of the eyes of an acute nature, you can use every hour, reducing the frequency of instillation in the future.
For the treatment of bacterial-type corneal ulcers, in the first six hours, a drop of the drug is instilled every 15 minutes, then every half hour, drop by drop, on the second day the drug is dripped every hour, then every four hours (up to six times a day).
In surgery, to prevent infectious complications, the medicine is instilled into each eye 1-2 drops once immediately before surgery, every 4-6 hours, 1-2 drops during the first day after it.
Instructions for drops "Ciprofloxacin-Akos" also does not contain information about patient reviews.
Reviews
"Ciprofloxacin-Akos" is an affordable tool for the treatment of pathologies of the organs of vision, which can be purchased at any pharmacy.
Some patients note that using eye drops is not very convenient, since the bottle is made of thick plastic, and at first there were problems with their dosage. The tube is very hard, so you need to make some effort to carry out the procedure.
The advantages of the drug include:
- wide range of its action;
- eliminate eye redness and pain,reduction in the size of the neoplasm;
- availability in many pharmacies;
- effectiveness in treating barley;
- democratic cost;
- no side effects (individual).
There are also disadvantages:
- is an antibiotic;
- eliminates the symptoms of chalazion, but the disease does not cure;
- slight burning sensation;
- An antibiotic is not very effective in treating chronic conjunctivitis.
We reviewed the instructions for Ciprofloxacin-Akos eye drops.
