In inflammatory and infectious diseases of the digestive tract and genitourinary system, a drug such as Macmiror is often used. Is it an antibiotic or not, how to use it, under what conditions it is not prescribed and whether it has side effects - the answers to these and other questions will be presented below.
Form of release, description and composition of the medicinal product
Most often, Macmirror is prescribed to patients in oral form, namely in the form of round and white film-coated tablets. The drug is placed in blisters and cardboard packaging, respectively. The active ingredient in this medication is nifuratel. As excipients are used: rice and potato starch, polyethylene glycol-6000, gum arabic (acacia gum), magnesium stearate, gelatin and talc.
Also, treatment with Macmirror is often carried out using vaginal suppositories. Their main component isnifuratel, and auxiliary - dimethicone, glycerin, gelatin, titanium dioxide, etc.
Another form of the agent in question is a cream for vaginal administration. Its active ingredient is also nifuratel. As for additional substances, they use xalifin, glycerin, purified water, sodium methyl parahydroxybenzoate, propylene glycol, carbomer, 30% triethanolamine, propyl parahydroxybenzoate and 70% sorbitol solution.
Therapeutic properties of the drug, the principle of its action
So, what is McMiror, is it an antibiotic or not? To answer this question, you should refer to the instructions. It says that the specified drug is an antiprotozoal and antimicrobial agent. The active substance of all forms of release of this medication is nifuratel. The latter has pronounced antibacterial and antifungal properties. Also, nifuratel is characterized by low toxicity and a wide spectrum of action in the human body.
According to reviews, the use of "Macmirror" contributes to the violation of the integrity of the membranes of Giardia, amoebas, anaerobic and aerobic bacteria, and also prevents their further reproduction.
The instructions for use of the drug say that the active ingredient of the drug is very quickly absorbed from the digestive tract, penetrates into the systemic circulation and is distributed to all tissues and organs.
Before using McMiror for giardiasis and other diseases, it should be borne in mind thatnifuratel is able to penetrate the hemoplacental barrier, as well as excreted in mother's milk.
The specified component is metabolized in the liver, and its excretion occurs unchanged with urine. At the same time, nifuratel has a strong antimicrobial effect in the organs of the urinary system.
McMiror is an antibiotic or not?
Before using the drug in question, a mandatory consultation with the attending physician is necessary. Self-medication with such a remedy is dangerous to he alth. Also, an incorrectly used drug can aggravate an already difficult patient's condition.
Answering the question, "Macmirror" is an antibiotic or not, experts say that such a tool exhibits pronounced antibacterial properties. It is highly effective against Gram-positive and Gram-negative bacteria.
The medication in question belongs to the group of nitrofuran antibiotics. It is characterized not only by antimicrobial and antibacterial activity, but also by antifungal and antiprotozoal properties.
According to doctors, this medicine is a broad-spectrum antibiotic. It can be used for various infectious and inflammatory diseases.
Indications for prescribing the drug "Macmirror"
According to the instructions and reviews, Macmirror is actively prescribed for exacerbation of infectious and inflammatory diseases in the urinary tract and intestines, as well asmucous membranes of other organs.
The main indications for the use of the agent under consideration are the following pathological conditions:
- vaginitis, vulvovaginitis, candidiasis, chlamydia and trichomoniasis;
- cystitis, pyelonephritis, urethritis and pyelitis;
- diseases of the digestive tract caused by Helicobacter pylori.
Also often prescribed "Macmirror" from Giardia and intestinal amoebiasis.
How to use an antibiotic drug
Macmirror tablets are for oral use, while the cream and suppositories are for vaginal administration.
Daily dosages of these forms of the drug are described in detail in the attached instructions. As a rule, they depend on the severity and type of the disease. For example, for vaginal infections, Macmirror is prescribed 1 tablet three times a day for a week (or 1 suppository at bedtime, or a vaginal cream twice a day, for a weekly course).
In intestinal amebiasis, the drug is used 2 tablets orally 2-3 times a day for 10 days. The oral medication must not be chewed. It must be swallowed whole and washed down with plenty of water.
For giardiasis and infectious lesions of the gastrointestinal tract, Macmirror is prescribed 2 tablets 2-3 times a day (weekly course).
In urinary tract infections, the daily dosage of the agent in question depends on the age of the patient. For adults, this medication is recommended to be used at a dose of 0.3–0.4 g per day (after takingfood).
When is it prescribed for men?
For the stronger sex, Macmirror is prescribed for inflammation of the bladder and urethra, pyelonephritis and urethritis, as well as as part of a complex treatment of sexually transmitted diseases.
The daily dosage of such a remedy depends on the nature of the patient's pathological condition and its stage. The optimal dose of this remedy for men is 1 tablet three times a day for 7 days.
Use during pregnancy and while breastfeeding
The instructions that came with the drug say that "Macmirror" is allowed to use during pregnancy, but only for medical reasons. As you know, the active substance of this agent is able to penetrate the placental barrier, but it does not have a teratogenic and toxic effect on the embryo.
When lactating, it is better to refuse the use of the drug in question. If medication is needed, the infant should be temporarily switched to adapted formulas.
Can I give to children?
According to the instructions, Macmirror is often prescribed for children. Usually in pediatric practice, such a drug is used for infectious and inflammatory diseases of the urinary tract. Daily dosages of the drug depend on the weight of the child, as well as the nature of the pathological condition (from 10 mg / kg to 15 mg / kg of body weight, twice a day for 7-10 days).
Medicinalinteraction
The Macmirror drug, used simultaneously with antifungal drugs (for example, with Nystatin), is able to enhance the therapeutic effect of the latter.
With the parallel use of an antibiotic with enterosorbents and antacids, the therapeutic effect of nifuratel decreases.
Concomitant use of an antibacterial agent with other antibiotic drugs or antiprotozoal drugs must be agreed with a specialist.
Overdose cases, side effects
In some clinical cases, after using the drug "Macmirror", the patient's well-being may noticeably worsen already at the very beginning of the course of treatment. The instructions indicate the following side effects that may occur while using this remedy:
- bitterness in the mouth, hives, nausea;
- skin rash, vomiting, swelling or hyperemia of the epidermis, signs of dyspepsia, abdominal pain, heartburn.
In the process of using the vaginal cream and suppositories, no cases of overdose were recorded.
With a systematic excess of dosages of the oral form of the drug "Macmirror" may increase side effects. In this case, the patient must independently induce vomiting, take sorbents, and then carry out symptomatic treatment (after consulting a doctor).
Contraindications to prescribing medication
According to the instructions, Macmirror Complex suppositories, as well as other forms of release of this medicine, have somecontraindications for use. These include the following states:
- high sensitivity of the patient to the components of the drug;
- breastfeeding period;
- pregnancy period (allowed for medical reasons only);
- prone to allergies.
Similar drugs
The most popular analogues of Macmirror are the following medicines:
- "Furazolidone" - oral tablets. They should be taken only after meals, otherwise a laxative effect develops. The daily dosage of such a medicine depends on the diagnosis.
- "Hexicon" - goes on sale in the form of vaginal tablets, suppositories, solution and gel for external use. Such a drug is prescribed for infections of the genital organs, as well as urological, venereal and gynecological diseases.
- "Vokadin" - available in the form of a solution, suppositories and ointments that exhibit bactericidal, antiviral and fungicidal properties.
- "Chlorhexidine" is a topical external antiseptic. It exhibits a wide spectrum of action, has a minimum of contraindications and side effects.
- "Osarbon" - vaginal suppositories that are highly effective in such a diagnosis as vulvovaginitis.
- "Betadine" - available in the form of ointment, solution and vaginal suppositories. The drug has antiseptic and disinfectant properties. Its active active ingredient can not only eliminate pathogenic flora, but also accelerateregeneration of affected tissues.
- "Ecovag" goes on sale in the form of vaginal capsules, which effectively manifest themselves in diseases such as vaginitis, chlamydia, urethritis and other infections of the genitourinary system. This medicine works only locally. Its main and auxiliary components do not penetrate the systemic circulation.
- "Iodoxide" is a local antiseptic. This drug is produced in the form of suppositories, which are intended for intravaginal administration.
