According to the instructions for use, Aspirin tablets are prescribed for adults and children if there is a need for a non-hormonal agent to stop the activity of inflammatory foci. The drug is prescribed primarily to relieve pain, as well as relieve fever. You can use "Aspirin" as an effective drug that prevents thrombosis.
When will it help?
Instructions for the use of Aspirin tablets says: the drug is indicated for the relief of pain symptoms. It is reasonable to use the medication for soreness of a weak and medium level of strength. The remedy is effective in the syndrome of various etiologies, including inflammatory processes. Widespread clinical practice is the use of tablets and powder "Aspirin" to relieve fever, a patient condition associated with rheumatic processes. You can use the medication as a prophylactic with an increased likelihood of embolism, the formation of blood clots.
In the instructions for the use of "Aspirin" children and adults are shown to use the composition inside. It is allowed to grind eacha copy of the medication before use in food, but this is not necessary: you can swallow the tablets whole. In any of the Aspirin options, you need to drink plenty of pure water without additives.
Nuances of application
In general, the instructions for use "Aspirin" 100 mg is recommended for use in the amount of 3-10 tablets at a time. You can repeat the reception after 4-8 hours. You can not use more than four grams of the drug in 24 hours. As a means to prevent embolism, blood clots, the drug is prescribed once a day in the amount of 1-3 tablets. The duration of the course varies from a month to a couple of years.
Instructions for the use of "Aspirin" 100 mg for children recommends taking a smaller amount than for adult patients. The specific dose is calculated based on the weight of the patient. For each kg of weight should be no more than 60 mg. The total dose is divided into 4-6 servings. You can use "Aspirin" at four-hour intervals at 10 mg / kg, or at six-hour intervals, increasing the dose by one and a half times.
Special case: for children - with caution
Instructions for the use of Aspirin tablets at temperature and to change blood viscosity, to relieve pain, it is allowed to use from the age of six months. When prescribing the drug to children under one year of age, a single dose varies between 50-100 mg. Until the age of three, it is allowed to use one tablet at a time, up to six years - two. For children in the age group 7-9 yearsit is allowed to use 300 mg of the drug at a time. Over nine years of age - 400 mg.
If the pathological condition is accompanied by fever, the instructions for use "Aspirin" is allowed only if other means have shown inefficiency. A study of numerous cases of drug use by children and adolescents showed that the risk of the formation of Reye's syndrome increases. This condition manifests itself as profuse vomiting that does not stop for a long time.
Indications: Aspirin Cardio
Instructions for use for this form of release indicates the effectiveness of the drug as part of a comprehensive course of recovery of the patient's condition after a heart attack. The drug is used to stabilize the brain in case of impaired blood flow in this organ.
"Aspirin Cardio" prevents blockage of blood vessels and is effective in inflammatory, infectious processes.
Do I need this?
As can be seen from the reviews, the instructions for using "Aspirin" are simple and clear, the price of the product is affordable for the general public, and the medicine itself is effective and fast acting. Many of our compatriots always keep Aspirin tablets on hand in order to quickly alleviate the condition in case of pain or fever. As a means for the main treatment, the drug is not used, it is indicated only as a means of relieving symptoms. This is also noted in the responses about the effectiveness of the remedy. It should be noted that the best opinion aboutmedicine has developed in those who used the pills under the supervision of a doctor. Aspirin is sold without a prescription and is available for purchase by anyone interested, however, you should coordinate the appointment with the doctor - it is safer and more effective.
Alternative: is there any?
Reviews, analogues, instructions for the use of "Aspirin", indications for taking it, possible side effects - all this information is of interest to many of our compatriots. While Aspirin is available to the general public, many are interested in an alternative. Someone needs a stronger remedy, others need more security or a slightly wider range of action. Currently, pharmacists can offer the following Aspirin analogues, the instructions for use of which contain a mention in the composition of acetylsalicylic acid:
- "Acetylsalicylic acid".
- "Trombo ACC".
- Upsarin Upsa.
Pharmacological features
In the instructions for use of Aspirin Cardio, the manufacturer indicates that the drug belongs to the class of non-steroidal anti-inflammatory drugs and stops the activity of inflammatory foci. It is a non-narcotic pain reliever. The drug reduces blood clotting. The main compound due to which the effect is achievable is acetylsalicylic acid. The drug irreversibly inhibits the activity of COX, an enzyme produced in the human body that is involved in the production of prostaglandins. In addition, COX is involved in the formation of prostacyclins, thromboxane.
The reduction in prostaglandin generation mentioned in the instructions for use of "Aspirin" leads to a weakening of the pyrogenic effect exerted by these compounds on the body's temperature-regulating centers. The activity of prostaglandins, which affects the sensitivity of nerve endings, decreases. The effect of pain mediators on the nervous system is reduced.
How it works: Continuing consideration
Instructions for the use of "Aspirin Cardio" draws attention to the irreversible process of preventing the formation of thromboxane. This explains the antiplatelet effect of the drug.
At the same time, the active compound of the tablets has a depressing effect on the COX of the endothelium, where prostacyclin is produced. This compound also has an antiplatelet effect. Studies have shown that endothelial COX is less affected by acetylsalicylic acid, when compared with the effectiveness of the platelet enzyme. In addition, inhibition of endothelial COX activity is estimated to be reversible. This explains the effectiveness of the drug as a blood thinner. In the instructions for use of Aspirin, the manufacturer indicates the need to use the product for this purpose carefully so as not to provoke excessive inhibition of the ability of the liquid to coagulate.
Specific composition
In the instructions for use of Aspirin Cardio, the manufacturer mentions the presence of several options for tablets: there is a drug made in capsules,coated with a thin film, there are effervescent tablets. The first release option is acetylsalicylic acid, protected by compounds that are resistant to the influence of gastric juice. The use of this option helps to minimize the likelihood of a negative effect on the gastric system.
Effervescent tablets, as stated in the instructions for use ("Aspirin Cardio" is not available in this form), contain sodium bicarbonate. This substance is able to enter into a hydrochloric acid neutralization reaction, which explains the increased acidity of the gastric environment. Under the influence of the substance, the indicators stabilize to 6-7 units, therefore, the irritating effect of the main element of the drug on the mucous membranes of the stomach and intestines decreases.
Important to know
Instructions for the use of "Aspirin Cardio", "Aspirin" special attention is paid to the use of the drug in the presence of liver diseases. Although this is not an absolute contraindication to taking the composition, the presence of such a diagnosis in the medical history makes it necessary to approach the development of a therapeutic program with particular care. Similar restrictions are associated with a history of gout.
You can not simultaneously take "Aspirin" and other drugs to relieve pain and stop the activity of inflammatory foci. This significantly increases the likelihood of side effects, may cause the ineffectiveness of each of the funds separately.
Mutual influence
As explained in the instructions for use"Aspirin", acetylsalicylic acid can stimulate the effect of methotrexate on the human body. This is due to a decrease in the clearance of the drug substance in the kidneys. In addition, the compound is displaced from binding to whey proteins.
The combination of acetylsalicylic acid and heparin enhances the effectiveness of the second substance. A similar effect is observed when combined with drugs that indirectly reduce the ability of blood to clot. The effect is explained by the effect on platelet function. Indirect anticoagulants are displaced by acetylsalicylic acid from their bonds with serum protein structures.
Combined therapeutic course, involving the intake of acetylsalicylic acid and thrombolytics, antiplatelet drugs, ticlopidine into the body, leads to increased activity of these groups of drugs. Instructions for use "Aspirin" clarifies that the drug reduces the clearance in the kidneys of digoxin, while simultaneously stimulating an increased content of this substance in the circulatory system. This leads to greater effectiveness of the formulation.
Combine Do No Harm: Joint Effects
In the instructions for use of "Aspirin" (tablets for blood thinning, pain relief and fever relief), the manufacturer specifies: acetylsalicylic acid makes hypoglycemic drugs more active and effective. This is especially pronounced with respect to insulin, the transformation products of sulfonylurea. The effect is explained by the hypoglycemic qualities of the acid itself, on which Aspirin is based, as well as its ability to displacesulfonylurea products from serum bonds.
The combination of uricosuric drugs and "Aspirin" is accompanied by a decrease in the effectiveness of the first group of drugs. Especially carefully it is necessary to prescribe acetylsalicylic acid if the patient is prescribed benzbromarone.
Combination with glucocorticosteroids is characterized by increased activity in the elimination of salicylates.
Too much
Using too much Aspirin can cause moderate to severe overdose. The first expresses itself with nausea and vomiting. The patient has noise in the ears, the ability to hear weakens, the head hurts and is spinning, the consciousness is confused. Severe poisoning indicates a feverish state and alkalosis, acidosis, increased pulmonary ventilation. Possible coma, failure of the lungs, heart and blood vessels. Severe poisoning with "Aspirin" can cause severe hyperglycemia. More likely to observe overdose in elderly patients.
Having revealed the fact of excessive use of "Aspirin", it is necessary to immediately provide first aid. With an average level of severity of the patient's condition, the dosage of the medication used is reduced, with a severe variant they are hospitalized. Emergency treatment involves taking activated charcoal, gastric lavage. It is necessary to take indicators to clarify the acidity of the environment in the gastrointestinal tract, to carry out diuresis, blood dialysis. A severe condition with an overdose of Aspirin requires infusions and a course of medications selected based on the symptoms of the case.
When conducting alkaline diuresis, the goal is toacidity level 7, 5-8 units. Forced diuresis is indicated if the serum fraction of salicylates exceeds 500 mg/g (for children, the upper limit is 300 mg/m).
Nuances of application
If "Aspirin" is prescribed for acute heart attack, the optimal dosage is 100 mg of medication for 24 hours. As a measure to prevent a recurrence of the situation, the dose is tripled.
To prevent stroke or blood flow problems in the brain, use 100-300 mg daily.
No way
"Aspirin" is contraindicated in persons suffering from erosion, ulcers in the stomach or intestinal tract. You can not use the drug for asthma, which is activated against the background of non-hormonal anti-inflammatory, salicylates. An absolute contraindication is the need to use methotrexate 15 mg per week or a higher dose. "Aspirin" is not prescribed if hemorrhagic diathesis, insufficiency of the kidneys, liver, as well as a decompensated form of insufficiency of cardiac functionality are detected.
"Aspirin" is contraindicated in high blood pressure and angina pectoris. The medication is not used if the thyroid gland is larger than normal. The drug is not suitable for the treatment of pregnant women in the first and third part of the period, as well as at the stage of breastfeeding.
"Aspirin" is contraindicated in case of hypersensitivity to acetylsalicylic acid. It should not be used if other salicylates have provoked a hypersensitivity reaction in the past. This also applies to the auxiliary components of the drug. Toto minimize the likelihood of a negative response of the body, you should carefully read the instructions for a specific release for the presence of compounds dangerous to a particular person.
Safety First
For patients under the age of fifteen, "Aspirin" is contraindicated in fever, SARS. Infection with viruses in combination with drug therapy can provoke Reye's syndrome. The term refers to a serious condition in which there is an insufficiency of the liver in an acute form, fatty hepatic degeneration and encephalopathy.
Special Occasion
It is allowed to use "Aspirin", but only if possible, regularly check the condition of the body if a person suffers from hyperuricemia or gout. People who have a history of peptic ulcers in the stomach, intestines, bleeding in this area, as well as malfunctioning of the liver or kidneys require a particularly careful attitude towards themselves. With caution, a remedy is prescribed when mentioning in the past episodes of bronchial asthma, allergies localized in the respiratory system, hay fever.
It is allowed to use "Aspirin" in the second third of the pregnancy period. The drug can be used only under the supervision of a doctor. Caution requires the use of the composition against the background of polyps in the nose and with a tendency to an allergic response to various medicinal compounds.
Is it dangerous?
It is forbidden to combine "Aspirin" andalcoholic drinks. Such a combination is more likely to provoke unwanted body responses, increase the toxic effect of drugs, alcohol. For the entire period of the therapeutic course, you should completely abandon any alcohol-containing foods, drinks.
Negative consequences: what is possible?
The manufacturer specifies in the instructions for use that in some cases, "Aspirin" provokes in patients a loss of appetite and pain in the abdomen. Tablets can cause loose stools and nausea. Some people develop ulcers, erosion, bleeding in the gastrointestinal tract against the background of the therapeutic course. There is a risk of an allergic response of the body. Laboratory studies may show a decrease in platelet concentration.
Possible vomiting while taking the drug, as well as hidden bleeding. With a probability of less than one percent, liver damage due to poisoning may develop. To a greater extent, such risks are characteristic of persons suffering from juvenile rheumatoid arthritis. With a similar frequency (less than one percent), anemia is recorded against the background of the use of Aspirin. There is a risk of acute glomerulonephritis.
An allergic response to medication can be expressed by skin manifestations, rashes, itching, urticaria, angioedema, allergic rhinitis, bronchospasm and shortness of breath.
