"Odeston" belongs to the group of choleretic drugs. It is actively used in a number of diseases of the gastrointestinal tract. What are the features of this drug? What effect does it have and does it have analogues?
Release form and active substance
The drug is available in the form of tablets with a flat-cylindrical shape. The color varies from white to yellowish, and on one side there is an engraving of Ch. The active substance is hymecromone, which has a choleretic effect. In addition to stimulating the formation of bile, it helps to relax the muscles of the excretory duct and the sphincter of Oddi (antispasmodic effect). Thanks to this, stagnation of bile does not occur, the digestive function is regulated. An additional effect of the drug is the prevention of cholesterol crystallization, which prevents the formation of cholesterol stones and the development of cholelithiasis. Tablets for parenteral administration have a fairly high bioavailability - they are quickly absorbed in the gastrointestinal tract and have their effect. The drug is excreted from the body by the kidneys. Often doctors prescribe exactly "Odeston". Its price is 300-360 rubles for 20 tablets. However, you can find a cholagogue with a lower cost.
Indications
This drug and analogues of "Odeston" are used in gastroenterological practice. It is prescribed for such pathologies:
- Sphincter of Oddi dyskinesia;
- biliary dyskinesia;
- non-calculous cholecystitis - chronic form;
- cholelithiasis;
- gall bladder interventions;
- cholangitis;
- nausea and vomiting due to bile hyposecretion.
Odeston is often used for pancreatitis.
When is contraindicated?
Absolute contraindication is hypersensitivity to the components of the drug. Enhanced secretion of bile after administration makes the drug prohibited for use with obstruction of the duct. Also, you should not prescribe it for ulcerative lesions, Crohn's disease, hemophilia. "Odeston" is contraindicated in severe renal or hepatic insufficiency and under the age of 18.
At the moment, there is no accurate information about the effect on the fetus during the treatment of pregnant women with Odeston. A direct teratogenic effect has not been established, but the use of the drug during pregnancy and lactation should still be avoided, since safety data have not been proven. Herbal analogues of "Odeston" have fewer contraindications.
Side effects
The drug in the presence of hypersensitivity can cause an allergic reaction, which is usually manifested by a skin rash and itching. Alsoflatulence, abdominal pain and headache are possible. With prolonged use, the medicine can provoke ulceration of the mucous membrane of the organs of the gastrointestinal tract.
Odeston: instructions, reviews
The medicine is prescribed 30 minutes before a meal. As a rule, adults are recommended to use 200-400 mg of Odeston 2 times / day. Thus, the daily dosage should not exceed 1200 mg. The medicine is not intended for long-term use - the course of therapy is usually 2 weeks. Before taking, be sure to consult with your doctor, who will select an individual dosage based on the patient's condition.
The drug has mostly positive reviews. It helps to improve the condition of patients with gastrointestinal diseases, while preventing the occurrence of severe complications. Patients report improved digestion and reduced symptoms such as nausea and vomiting.
Interaction with other drugs
"Odeston" is incompatible with metoclopramide, since when these drugs are taken together, a two-sided decrease in the effect occurs. Also, you should not combine it with indirect anticoagulants: the effect of the latter is greatly enhanced. This threatens the development of hemorrhagic phenomena. The effect of Hymecromon is reduced when the drug is taken together with morphine.
Analogues of Odeston
This name was given to drugs that have a similar effect with this. With their help, you can replace the medicine, but before that it is better to talk with your doctor. Maybe,replacement of the drug with an analogue is unacceptable in this clinical situation. Similar drugs have almost the same indications. Odeston has several analogues.
Hofitol
The preparation is herbal - its basis is an extract from the field artichoke. The drug has not only a choleretic effect, it also helps to restore liver cells and has a mild diuretic effect. Also, thanks to "Hofitol", the production of liver enzymes is normalized, which improves the metabolism of cholesterol and fats. The composition contains vitamins B1, B2 and C, which additionally stimulates metabolism. Plant origin allows the use of the drug at any age. Among the contraindications to this drug are hypersensitivity, obstruction of the duct by a stone or tumor, as well as acute forms of diseases of the liver, gallbladder, and kidneys. Care should be taken to prescribe "Hofitol" to people with renal and hepatic insufficiency. Some analogues of "Odeston" have a lower cost. So the price for 60 tablets of "Hofitol" is 220-300 rubles.
Allohole
This medicine, like the previous one, contains herbal ingredients. Its composition is animal dry bile, nettle and garlic extracts and activated charcoal. The drug has a pronounced choleretic effect, normalizes the production of bile and prevents the formation of stones. In addition, there is stimulation of the secretion of other organs of the digestive system. The drug is also used in chronic hepatitis, uncomplicated cholelithiasis,initial cirrhosis of the liver, after removal of the gallbladder. Unlike Odeston, the price is 30-50 rubles for 24 tablets.
Cholagogue drugs are needed in violation of the outflow of bile. However, they are contraindicated in the complete absence of bile excretion due to obstruction. In this case, another treatment is required. Any pathology of the digestive and other systems requires medical intervention, so therapy should be agreed with a specialist.
