What is the dosage of Bronchobos (syrup)? Instructions for use of the mucolytic drug are described in detail below. Also in the materials of this article you can find information about the purposes for which the mentioned medication is used, how much it costs, whether it has adverse reactions, analogues and contraindications.
Composition and packaging
In what package does Bronchobos (syrup) go on sale? Instructions for use of the mucolytic agent are enclosed in a cardboard box containing a measuring spoon made of polystyrene with marks, as well as a dark brown glass bottle with an aluminum cap with a seal, a protective mechanism and a first opening control.
The active substance of this medication is carbocysteine. It also contains auxiliary compounds in the form of ethanol, glycerol, sodium hydroxide, citric acid monohydrate, sodium carmellose, methyl parahydroxybenzoate, propyl parahydroxybenzoate, sodium saccharinate, azorubine, raspberry flavor and purified water.
Bronchobos syrup, reviews of which are described below, is a 2, 5% or 5% transparent drug with a slightly viscoustexture, raspberry flavor and bright red color.
Drug pharmacodynamics
Mucolytic drugs, including Bronchobos syrup, have an expectorant effect. This effect of the drug is due to the activation of the enzyme - sialic transferase, which is produced in goblet cells in the bronchial mucosa.
The drug normalizes the numerical ratio of acidic and neutral sialomucins in bronchial secretions. In addition, it restores the viscosity of mucus and its elasticity.
What other features do mucolytic drugs have? They contribute to the regeneration of mucous membranes, normalize the structure, and also activate the work of the ciliated epithelium. Syrup "Bronhobos" restores the secretion of immunoglobulin A as a specific protection, as well as the number of sulfhydryl groups in the mucus and its components as a non-specific protection. It also improves mucociliary clearance.
Pharmacokinetic parameters of the drug
The drug "Bronhobos", the price of which will be indicated below, is absorbed quickly and completely. At the same time, it has a rather low bioavailability (less than 10% of the dose taken). The highest level of active carbocysteine in the mucous membranes and blood is reached after 1.5-2 hours. Its therapeutic level is maintained for 8 hours. The drug stays the longest in the liver, bloodstream and middle ear. At maximum concentrations, it accumulates in bronchial secretions (about 17.5% of the accepteddose).
The drug is metabolized in the liver. It has a first pass effect. Approximately 60-90% of the drug is excreted by the kidneys in unchanged form.
The half-life of the drug is 2-3 hours. Its complete elimination occurs after three days.
Indications for the use of syrup
For what purposes is Bronchobos prescribed for children and adults? According to the instructions, this syrup effectively helps with:
- inflammatory processes occurring in the paranasal sinuses and middle ear, including sinusitis, rhinitis and otitis media;
- chronic and acute bronchopulmonary diseases accompanied by impaired mucus excretion and secretion (for example, bronchitis, tracheitis, bronchial asthma, tracheobronchitis and bronchiectasis).
In addition to the above, the medication in question is actively used during the preparation of the patient for bronchography or bronchoscopy.
Contraindications for use
Under what conditions is it not recommended to take Bronchobos (syrup)? Instructions for use speaks of the following contraindications for all dosage forms:
- duodenal ulcer and stomach ulcer (especially during exacerbation);
- hypersensitivity to drug components;
- cystitis and chronic glomerulonephritis (including exacerbation);
- under 15 years old.
For 2, 5% and 5% syrup:
- epilepsy;
- various liver diseases,alcoholism;
- brain diseases and injuries of this organ;
- breastfeeding and pregnancy.
For 2.5% syrup:
under 3 years old
Conditions for careful drug use:
- presence of a history of duodenal ulcer and stomach ulcer.
Drug: "Bronhobos" (syrup): instructions for use
According to the attached instructions, this medication must be taken orally. The dosage of the drug should be determined using a measuring spoon.
For adults, the drug is prescribed in an amount of 15 ml, which is equal to 3 scoops of 5% syrup (three times a day).
Children aged 3-6 years 2.5% medication is given 5 ml 2-4 times a day, that is, in the amount of 1 scoop at a time.
Children from 6 years of age are prescribed 5-10 ml of 2.5% syrup three times a day, that is, 1-2 measuring spoons.
Drug overdose
When taking high doses of syrup, the patient may experience stomach pain, diarrhea and nausea. To eliminate such deviations, symptomatic treatment is prescribed.
Side effects
Taking the medication "Bronhobos" can cause undesirable effects from the following organs and systems:
- Gastrointestinal tract: epigastric pain, nausea, bleeding, vomiting, diarrhea.
- Immune system: allergic reactions in the form of exanthema, urticaria, pruritus, angioedema.
- Other: dizziness, weakness,malaise.
- People with asthma and elderly patients may experience airway obstruction.
Drug Interactions
When taking any dosage forms of the drug:
- The bronchodilator effect of the drug "Theophylline" is increased.
- In the treatment of infectious and inflammatory processes in the lower and upper respiratory tract, there may be a mutual increase in glucocorticoid efficacy, as well as a separate antibacterial effect.
- With atropine-like drugs, the antitussive effect is weakened.
When taking syrup:
- Use with extreme caution (due to the presence of ethanol) with drugs that cause fever, vomiting, redness and tachycardia.
- With extreme caution (due to the presence of ethanol), they are taken with drugs such as Cefamandol, Disulfiram, Cefoperazone, Latamoxef, Chloramphenicol, Glipizide, Glibenclamide, " Chlorpropamide, Tolbutamide, Griseofulvin, Metronidazole, Tinidazole, Seknidazole, Ornidazole, Procarbazine, Ketoconazole.
Special Recommendations
Bronchobos syrup contains ethanol. In this regard, it is prescribed with caution to children and people suffering from alcoholism. After taking the drug, patients experience impaired attention and speed of psychomotor reactions. In this regard, the use of this medication is not recommended for drivers of vehicles and those who work with complex mechanisms.
Terms of sale, storage and shelf life
Sold such a drug in pharmacies without a doctor's prescription. It should be stored out of the reach of children, observing the temperature regime of 16-30 degrees. The syrup has a shelf life of three years (without breaking the package).
Bronhobos drug: analogues and cost
Currently, there are many analogues of the means in question. The closest in mechanism of action is the drug "Fluifort" (syrup). It is also a good mucolytic. In addition, the presented medication can be replaced by such means as Fluditec, Bronkatar, Libeksin Muko, Mukopront and Mukosol.
How much does Bronhobos cost? The price of this medicine depends on its form of release. 5% syrup can be purchased for 550-570 rubles, and 2.5% drug - for 420 rubles.
Medication reviews
Just like Fluifort, Bronchobos syrup is a high-quality and effective mucolytic. This is the opinion of the majority of patients who have used this medication for the treatment of chronic and acute bronchopulmonary diseases.
According to the opinion of experienced professionals, this drug is able to quickly and effectively thin and remove sputum from the bronchi. Another advantage of this tool is that it can be given to young children from two years old, as evidenced by many reviews. This is due to the fact that the syrup in question has practically no side effects and contraindications.
As for the negative reviews, most often they are associated with the price of the mucolytic drug. However, pharmacists claim that the cost of this drug is fully justified, as it is one of the most effective drugs against bronchopulmonary diseases.
