To treat such a pathological condition as hypertension, when a person's blood pressure rises regularly, it is necessary to use various medications. The choice of drugs is carried out individually for each patient, taking into account the state of his he alth, the stage of progression of the disease, the presence of concomitant pathologies. During treatment, specialists try to prescribe effective drugs for pressure without side effects.
It should be noted right away that absolutely safe drugs do not exist - each of them has certain contraindications and can cause side reactions. However, there are such means, the negative impact on the body of which is minimal. We will talk about pressure pills without side effects below.
Pressure standards
Hypertension today is a very urgent problem for all groupspopulation. But most often it affects the elderly, for whom it is very important that the medication for high blood pressure does not worsen their well-being and does not affect the course of chronic diseases.
The most optimal pressure in adults is considered to be 120/80 mm Hg. Art. The reduced pressure is 100-110 / 70-60 mm Hg. Art. Slightly increased is considered an indicator of 130-139 / 85-89 mm Hg. st, however, for hypotensive patients, this value indicates a very high pressure. In medicine, a tonometer indicator of more than 140/90 mm Hg is considered high. st.
Since age causes a variety of natural changes in the human body, this must be taken into account when measuring pressure. Adolescents and children often have low blood pressure. While in old age higher values are typical.
Drugs to lower pressure without side effects should be selected by a doctor.
Main drug categories
Before considering drugs for hypertension, it is necessary to know what categories of drugs exist. There are several such groups:
- Beta blockers. This group of medications is used to reduce blood pressure by reducing heart rate. Such drugs have some negative effects, so they are not shown to all hypertensive patients. Among them stand out: weakness in the body, a rash on the skin, as well as serious changes in the heartbeat. Pressure pills without side effects can be difficult to find.
- ACE inhibitors. The human body produces various hormones, and in somecases, their production is very intense, which negatively affects the cardiovascular system. They can narrow the walls of blood vessels and cause an increase in blood pressure. The described category of drugs helps to reduce the release of certain hormones and stops their action. Due to this, pressure is reduced by dilating blood vessels. Such drugs also cause adverse reactions, among which it is necessary to indicate a dry cough. If such a symptom occurs, the medication should be discarded and the treatment regimen adjusted. What are blood pressure medications without side effects?
- Diuretics. This group of drugs is represented by diuretics, which can quickly reduce pressure by removing excess fluid from the body. It is better to take pills of this direction in short courses, as they can have a negative effect on the heart. It can also cause seizures, dizziness, and mild nausea.
- Calcium antagonists. The main action of this group of drugs is to relax the vascular walls, due to which the pressure indicator decreases. Such drugs also have some side effects, and among them, hot flashes, increased heart rate, and dizziness stand out.
- Angiotensin antagonists. An increase in pressure may occur due to the influence of angiotensin 2, and medicines from this category can block its effect. After taking, nausea and dizziness may develop.
To choose the right drugs to normalize pressure without side effects, it is best to consult a doctor. After carrying out the necessary diagnostic measures, he will be able to prescribe a therapy regimen that will most effectively help reduce pressure with minimal negative consequences.
The safest blood pressure drugs without side effects
When there is a need to reduce pressure, many patients are interested in which drug to choose so as not to harm their body. It should be noted that there are no safe drugs, and in any case, each organism is individual and may react differently to certain medications.
Among the best high blood pressure pills without side effects is a new generation of medicines that are very convenient to use and much safer than drugs that have been around for decades.
New drugs have the following properties:
- Minimum adverse reactions. Due to the new formulas, all components of such drugs are selected in such a way that the negative impact on the human body is minimized, while the effectiveness of therapy is quite high.
- Prolonged action. The active elements of the new generation tablets have a cumulative effect and act for a long time after taking. This leads to the fact that it is enough for the patient to take only 1 tablet per day from pressure.
- Complex impact. Modern drugs affect several processes at the same time, which allows you to quickly normalize blood pressure and save a person from the unpleasant symptoms of hypertension.
As an addition to treatment with high blood pressure drugs without side effects, traditional medicine can be used. In this case, it is recommended to take decoctions and infusions of herbs, other natural ingredients, add honey, which has a positive effect on the cardiovascular system.
The best medicines for lowering blood pressure without side effects include the latest drugs for hypertension. They will be discussed below.
What are the most effective blood pressure drugs without side effects?
Lisinopril
An effective pressure reducer that includes several active elements. Due to this, the drug does not have high toxicity compared to many analogues.
This drug for high blood pressure without side effects belongs to the category of ACE inhibitors, and it contains an element from the group of diuretics, which greatly enhances the effectiveness of this drug. Doctors often recommend Lisinopril to older people who have been diagnosed with hypertension. After using the drug, a cumulative effect occurs. It is successfully prescribed for diabetes mellitus, since the active substances of the drug do not have a negative effect on the concentration of glucose in the blood. Result from treatmentcelebrated after a few hours and lasts throughout the day.
The main functions of the drug for high blood pressure without side effects are:
- increasing the endurance of the heart muscle in case of heart failure;
- reducing the likelihood of developing heart disease;
- normalization of pressure within normal limits, a decrease in values below the norm does not occur:
- drug approved for use in diabetes.
If any side effects appear while taking this medication, they usually do not lead to negative consequences and can only provoke dry mouth, dry cough, excessive sweating and dizziness. What else can be attributed to drugs to reduce pressure without side effects?
Physiotens
An effective drug that differs from others in the almost complete absence of side effects. According to the annotation for use, the medication can only cause dry mouth, as well as excessive drowsiness. The described symptoms occur in extremely rare cases, and most often hypertensive patients do not feel them.
That is, these are high blood pressure pills without side effects. The decrease in performance during treatment with this medication is mild, the functionality of the respiratory organs is not disturbed, so it can be prescribed even to patients with bronchial asthma. This remedy may increase insulin sensitivity, which means that it can be used in diabetes.
BThe composition of this medication contains the main substance - moxonidine. The mechanism of its action is due to the influence on the central structures of the regulation of blood pressure. Moxonidine acts as an agonist of imidazoline receptors, and by stimulating the neurons of the solitary tract through inhibitory interneurons, the substance helps to suppress the functions of the vasomotor center and reduce the downward sympathetic effect on the cardiovascular system. This drug differs from other sympatholytic antihypertensive drugs in its reduced affinity for α2-adrenergic receptors, which leads to a lower risk of developing sedative effects and dry mouth. What drugs reduce blood pressure without side effects, it is important to find out in advance.
Losartan
This medical product is included in the category of sartans. Its pharmacological action allows you to block enzymes that contribute to vasoconstriction. The effect after taking the medication appears almost immediately and lasts for 6 hours. An increase in blood pressure is not usually observed throughout the day.
It is allowed to use the drug in the presence of diabetes. The agent is well tolerated, it is very convenient to use it, since it is enough to take 1 tablet per day. In certain cases, patients may experience headaches, nasal congestion, dry mouth.
This medicine contains two main components - potassium losartan and hydrochlorothiazide. These substances havepronounced additive antihypertensive effect, reduce pressure to a greater extent than both components separately. This effect is due to their complementary influence. As a result of the diuretic properties, hydrochlorothiazide enhances plasma renin activity, stimulates the production of aldosterone, increases the concentration of angiotensin II and reduces the concentration of potassium in the blood. Taking the medication allows you to block all the physiological consequences of the action of angiotensin II and, as a result of the suppression of aldosterone activity, can help reduce the loss of potassium that is associated with taking a diuretic. The drug "Losartan" has a transient and weak uricosuric effect. Hydrochlorothiazide contributes to a slight increase in the concentration of uric acid in the blood. The combination of the main substances helps to reduce the severity of diuretic-induced hyperuricemia.
This medication is quite effective at any stage of the development of arterial hypertension.
Captopril
Modern drug for pressure without side effects "Captopril" is a very well-known drug that belongs to the category of ACE inhibitors and allows you to quickly lower your blood pressure, which is why it is successfully used for emergency care in hypertensive crises. However, this remedy is not recommended for long-term therapy, since it has a very active composition, which can reduce blood pressure below normal and provoke other negative symptoms. In some cases, specialists prescribe "Captopril" together with medicines from anothercategories. But at the same time, it is very important to constantly monitor the pressure indicators.
Medication "Captopril" helps to improve the functioning of the heart, all internal organs, when taken, receive a sufficient amount of useful elements, the likelihood of thrombosis decreases.
Restrictions on the use and side effects of this medicine still has, but they occur in rare cases. In this case, there may be a violation of the heart, a change in the rhythm of its contractions, an excessive decrease in pressure and dizziness. It is forbidden to use the medication for vascular stenosis, during pregnancy and lactation, with kidney failure.
Renipril GT
This is a drug that reduces blood pressure without side effects, a combined composition in which there are two active substances - enalapril maleate and hydrochlorothiazide. "Renipril GT" is a prodrug, due to its hydrolysis, an ACE inhibitor, enalaprilat, is formed. Hydrochlorothiazide is a category of thiazide diuretics. It enhances the processes of excretion of chloride and sodium ions, acting through the distal tubules of the kidneys.
For treatment with this medication, it is characteristic that in the initial period the decrease in pressure and cardiac output is carried out by reducing the volume of fluid in the vessels. Further, the antihypertensive effect is due to a decrease in peripheral vascular resistance. The inhibitory effect on the renin-angiotensin-aldosterone system provokes a decrease in the production of angiotensin II andenhances the hypotensive properties of hydrochlorothiazide. In addition, the release of prostaglandins and the effects of bradykinin increase, and the production of aldosterone decreases. Further, the heart rate slows down, with chronic heart failure - a decrease in the load on the heart, normalization of coronary blood flow, a decrease in oxygen consumption by heart cells.
The drug has a positive effect on blood circulation in the brain and spinal cord in hypertension and cardiovascular pathologies, prevents the development of glomerulosclerosis, slows down the course of chronic kidney disease, supports their functions.
The antihypertensive effect of this drug is enhanced by hypovolemia, hyponatremia. The presence of enalapril in its composition weakens or prevents the metabolic effects of diuretic treatment, has a beneficial effect on changes in blood vessels and the heart.
The drug "Renipril GT" rarely causes side effects, but among them there may be:
- allergic reactions;
- renal artery stenosis.
Despite the negative effects described above, it is extremely rare, and medication is most often prescribed for a long time.
Let's take a look at some more of the latest blood pressure drugs without side effects.
Indapamide
An antihypertensive agent from the category of thiazide-like diuretics based on the active element of the same name. The drug helps to reduce tonevascular smooth muscle, decrease in peripheral vascular resistance, has a slight saluretic activity, which is due to a violation of the reabsorption of chloride, sodium and water ions in the proximal convoluted tubule of the nephron and the cortical section of the loop of Henle.
The decrease in peripheral vascular resistance is due to such mechanisms: a decrease in the sensitivity of the vascular walls to angiotensin II and norepinephrine; increased production of prostaglandins with vasodilating activity; suppression of the entry of calcium ions into smooth muscle vascular walls.
In therapeutic dosages, this remedy has practically no effect on carbohydrate and lipid metabolism. Its hypotensive effect occurs only at initially high pressure. If there is a need to correct a small increase in pressure, then the tablets are prescribed in small doses.
The main advantages of the drug from pressure without the side effects of "Indapamide":
- medication easy to use, no need to take pills frequently;
- security;
- does not affect blood sugar, which makes it possible to use in diabetes;
- medication is allowed in case of hormonal failures;
- heart function normalizes;
- well tolerated.
This remedy is not recommended for patients with lactose intolerance, kidney or liver failure.
Veroshpiron
These blood pressure pills without side effects are classified as diuretics, but they do not remove potassium from the body. Typically, this medicine is prescribed asan additional drug when combining drugs for hypertension. In order to avoid adverse reactions, tablets should be taken strictly according to the prescription of a specialist. It is not recommended to carry out long-term therapy with the drug, because of this, hormonal disruptions may occur.
In the instructions for the drug "Veroshpiron" the drug is described as a potassium-sparing diuretic. Its main active ingredient (spironolactone) competes with aldosterone (hormone of the adrenal cortex) and slows down its action. Na+, Cl- and water are not absorbed back in the tubules of the kidneys, while urea and K+, on the contrary, penetrate into the blood through the endothelium of the vascular glomerulus. Increased urination provokes a decrease in blood pressure and elimination of puffiness. The diuretic effect occurs only after 3-5 days of treatment. "Veroshpiron" can be considered a drug that practically does not cause side effects, since it does not significantly affect the functionality of the renal tubules and does not cause acid-base imbalance in the body.
Diuver
May be considered a blood pressure medicine without side effects. This is the so-called "loop" diuretic, which contains the only active substance - torasemide. The mechanism of action of this drug is due to the reversible bond of torasemide with the Na+/Cl-/K+ contraporter, localized in the apical membrane of the ascending loop of Henle. As a result, the reabsorption of sodium ions is reduced or completely suppressed and the reabsorption of water and osmoticfluid pressure inside cells. The drug blocks aldosterone receptors in the heart muscle, reduces fibrosis and normalizes the diastolic function of the heart.
Torasemide causes slight hypokalemia, but it is highly active and differs in the duration of its action.
As for the side effects of this drug, they are somewhat more than other drugs for hypertension. However, if taken correctly and only on the recommendation of a doctor, negative reactions may not occur. "Cordaflex" is a pressure medicine without side effects based on the active element nifedipine. This medication belongs to the category of selective slow calcium channel blockers and has antihypertensive and antianginal effects.
Nifedipine reduces the current of extracellular calcium ions into the smooth muscle cells of peripheral and coronary arteries and cardiomyocytes, uncouples the processes of contraction and excitation of blood vessels mediated by calmodulin. In therapeutic doses, the drug normalizes the transmembrane current of calcium ions, which is disturbed in some pathological conditions, primarily in hypertension. In addition, the medication reduces afterload and the heart's need for oxygen. At the same time, the blood supply to ischemic areas of the myocardium is normalized without the occurrence of the “steal” syndrome, and it also increases the number of functioning collaterals.
Nifedipine has no effect on the sinoatrial and AV nodes and has an antiarrhythmic effect. In addition, the drug does not affect the tone of the venouswalls. The main substance increases blood flow in the kidneys, provokes moderate natriuresis. In high doses, it inhibits the release of calcium from intracellular calcium depots.
Side effects from this drug are usually mild, and most often patients experience disorders of the nervous system - dizziness, drowsiness, and palpitations.
Drugs for elderly patients
In old age, the state of blood vessels deteriorates significantly, they become less elastic, and after 50 years, people often begin to increase blood pressure. To reduce its performance, the following medications for pressure without side effects are used:
- Diuretic drugs that allow you to gently but effectively lower blood pressure and remove excess fluid. For therapy, it is recommended to use a drug such as Hypothiazid. This is an inexpensive but effective medicine, but it is not used in the advanced stages of hypertension. Indapamide may also be used, especially if the older person has volume-dependent hypertension.
- Calcium channel blockers. Among such medicines in old age, it is preferable to use the Nifedipine remedy.
- Combination drugs.
The list of blood pressure pills without side effects is constantly expanding.
Conclusion
Medical practice shows that the list of the most effective means to lower pressure includes medicines that are very toxic to the body. Nevertheless, there are drugs that cause a minimum of side effects, allow you to gently lower blood pressure, without severe harm to he alth. It should be borne in mind that such drugs are best taken systematically and planned to treat hypertension. Otherwise, people often experience hypertensive crises, which pose a serious danger to life, especially in old age. In order to choose the right medication, to minimize the risk of adverse reactions and serious complications, it is best to consult a doctor. The specialist will conduct an appropriate diagnosis of the pathological process, find out what causes the change in blood pressure indicators, and prescribe competent treatment.
We reviewed the most popular blood pressure drugs without side effects.
