"Paracetamol" is a medicine that belongs to the group of antipyretics. The drug has a pronounced analgesic, as well as antipyretic and anti-inflammatory effect. "Paracetamol" is part of many painkillers that are used to eliminate the signs of SARS.
The drug is produced in several dosage forms. For example, a drug in tablets for oral use is packaged in blisters of ten, twelve pieces. To understand whether Paracetamol is harmful to he alth or not, it is important to know exactly how this medicine works on the body.
Anti-inflammatory, antipyretic and analgesic properties of the drug are provided by the action of the active ingredient on the thermoregulation center in the brain. Many anti-inflammatory drugs have a pronounced negative effect on the gastric and intestinal mucosa.
What are the positive properties of the drug
Is it harmful to drink "Paracetamol"? The drug is detrimentalaffects the body in case of overdose. Subject to the instructions, the medication has an antipyretic, as well as analgesic and anti-inflammatory effect on the body. When the drug enters the stomach, the active substance is absorbed into the blood. The drug is quickly and completely absorbed into the gastrointestinal tract. The half-life varies from one to four hours.
Indications
Pills are given to people under the following conditions:
- Arthralgia (periodic occurrence of pain in the joints, in the absence of characteristic signs and symptoms of their defeat).
- Algodysmenorrhea (pain during menstruation due to infantilism, improper position of the uterus, inflammatory processes in the genital organs, endometriosis and other diseases, as well as increased excitability of the central nervous system).
- ARVI (a group of clinically and morphologically similar acute inflammatory diseases of the respiratory organs, the causative agents of which are pneumotropic viruses. SARS is the most common group of diseases in the world, combining respiratory syncytial infection, rhinovirus and adenovirus infections and other catarrhal inflammations of the upper respiratory tract).
- Migraines (a primary form of headache characterized by intermittent attacks of moderate to severe headache).
- Neuralgia (a pathological condition that progresses due to damage to certain parts of the peripheral nerves).
- Fever in viral and infectious diseases.
- Fever with colds and flu.
When it is forbidden to use "Paracetamol"
As written in the annotation, before using the medication, the patient must read the instructions. "Paracetamol" is forbidden to use in the following cases:
- Individual intolerance.
- Severe disorders in the functioning of the liver and kidneys.
- Liver failure.
- Children under 3 years of age.
- Pregnancy in the first trimester.
- Chronic alcoholism.
With extreme caution, "Paracetamol" is used in the subsequent trimesters of the "interesting position" and during lactation.
How to take medicine correctly
Single and daily dosing of "Paracetamol" is determined by the doctor depending on age, weight, severity of pain or fever.
Adults and children from 12 years of age are prescribed 0.5-1 grams, one to two hours after a meal, the maximum concentration of the drug is up to 4 g per day. The interval between the use of the medication must be at least four hours.
In people with liver or kidney damage, as well as Gilbert's syndrome and in elderly patients, the daily dosage should be reduced and the interval between doses should be increased.
Is "Paracetamol" harmful to children? As written in the annotation, the drug is forbidden to use only for babies up tothree years. The dosage of the medication is calculated based on the age and body weight of the child:
- Daily concentration from three to six years (with a weight of 15 to 22 kilograms) - 1 gram.
- Up to nine years (up to 30 kg) - 1.5 g.
- Up to twelve years (up to 40 kg) - 2 grams.
Frequency of application - four times a day; the time interval between each dose should be at least four hours. If unpleasant symptoms persist, it is worth contacting a medical specialist.
Recommendations
The tablet can be taken with or without food, with water. Do not increase the indicated dosing on your own. Paracetamol should not be used for more than five days as an analgesic and for more than three days as an antipyretic without the permission of a medical specialist. Increasing the daily concentration of the drug or increasing the duration of therapy is possible only under the supervision of a doctor.
Can I take medication during an "interesting" position
Is "Paracetamol" harmful during pregnancy? In the first three months, tablets, like any other drugs, should not be used, as this can adversely affect the intrauterine development of the fetus.
In the subsequent trimesters of pregnancy, the use of "Paracetamol" is possible only under the supervision of a medical specialist.
Treatment with "Paracetamol" during lactation must be agreed with the doctor. Substanceis excreted in breast milk, so if necessary, the baby should be transferred to formula.
Does the drug cause side effects
What harm does Paracetamol do to the body? As written in the annotation, while using the medication, people may experience certain side effects:
- Nausea.
- Urticaria (a skin lesion characterized by the rapid appearance of intensely itchy blisters on the skin).
- Gagging.
- Quincke's edema (an acute disease characterized by the appearance of clearly limited angioedema of the skin, subcutaneous tissue, and mucous membranes of various organs and systems of the body).
- Diarrhea.
- Increased activity of liver transaminases.
- Pain in the gastrointestinal tract.
- Agranulocytosis (a disease that is characterized by a decrease in the content of granulocytes in the blood).
- Neutropenia (a pathological condition in which the number of neutrophils in the body drops sharply).
- Flatulence (excessive accumulation of gases in the intestines).
- Liver enlargement.
- Increased heart rate.
- Changing blood pressure settings.
- Tachycardia (a type of arrhythmia characterized by a heart rate of more than 90 beats per minute).
- Anemia (a pathological condition characterized by a decrease in the concentration of hemoglobin and, in the vast majority of cases, the number of red blood cells per unit volume of blood).
- Decrease in the number of platelets and white blood cells.
- Pyuria (inflammatory processurinary system, characterized by purulent content in the urine).
- Interstitial nephritis (a common ailment characterized by acute or chronic abacterial inflammation of the interstitial tissue and tubules of the kidneys).
- Glomerulonephritis (inflammation of the glomeruli of the kidneys of an autoimmune or infectious-allergic nature, which is manifested by edema, increased blood pressure, decreased urine output).
- Impaired kidney function.
- In severe cases, the development of kidney failure.
- Angioneurotic edema (acute condition, which is characterized by the rapid development of local swelling of the mucous membrane, subcutaneous tissue and the skin itself).
- Pancreatitis (inflammation in the pancreas in which there is a development of deficiency in the production of pancreatic enzymes of varying severity).
- Arrhythmia (a pathological condition leading to a violation of the frequency, rhythm and sequence of excitation and contraction of the heart).
- Skin rashes like hives.
- Hyperemia (overflow of blood vessels of the circulatory system of any organ or area of the body).
If these negative effects appear when taken, a person should consult a specialist.
Is "Paracetamol" harmful to the stomach? It is known that the drug is contraindicated in patients with gastritis, since the drug irritates the mucous membrane, and its use can lead to an exacerbation of unpleasantsigns.
"Paracetamol" raises or lowers blood pressure
As far as we know, the drug has no effect on blood pressure readings. The drug "Paracetamol" can help stabilize pressure only indirectly, if its increase is a reaction to pain (by reducing their severity, the drug normalizes the indicators).
Drug Interactions
When using "Paracetamol" with inducers of microsomal liver enzymes, as well as drugs that have a hepatotoxic effect, there is a risk of increased hepatotoxic effects. When combined with anticoagulants, a slight or moderate increase in prothrombin time is likely.
Simultaneous use with anticholinergic drugs reduces the absorption of Paracetamol. Combining the drug with oral contraceptives may reduce the analgesic effect of the analgesic.
When combined with uricosuric drugs, their effectiveness decreases. Activated charcoal reduces the bioavailability of Paracetamol.
Features of therapy
People who have a history of severe liver damage should consult a specialist before treatment and take blood tests to determine liver transaminase activity.
If it is necessary to use the medication for a long time, it is important for a person to control blood counts. In pediatrics, the drugprescribed in the form of a suspension, which is allowed to be given to children from two months.
Is "Paracetamol" harmful to the liver? If we talk about the effect of the drug on this organ, it should be noted that it is this remedy that acts as a direct hepatotoxin. This means that the more "Paracetamol" the patient used, the higher the likelihood of developing hepatitis and liver failure.
Reviews
Most of the reviews about the drug are positive. "Paracetamol" shows a good effect in these diseases.
In general, patients respond remarkably well to the drug. The drug quickly eliminates the temperature, eliminates unwanted reactions and is well tolerated by people of different ages. Doctors believe that it is important to choose the right dosage form and calculate the dosage during therapy.
