"Sonizin" is used to eliminate violations of the process of emptying the bladder, which are associated with benign prostatic hyperplasia. The drug is produced in the form of capsules with a modified release. The composition of the medicine includes the following substances:
- tamsulosin hydrochloride;
- calcium stearate;
- citric acid ethyl ester;
- talc;
- ethyl acrylate copolymer;
- methacrylic acid;
- cellulose.
The article will consider reviews, instructions for use and analogues of "Sonizin".
Pharmacological actions
The drug belongs to alpha-blockers. Due to the action of the drug, a decrease in the tone of the smooth muscles of the prostate is observed. This leads to a reduction in the signs of irritation that are associated with benign prostatic hyperplasia.
The therapeutic effect usually occurs two weeks after the start of the use of "Sonizin", although in some patientsa decrease in the severity of symptoms is noted already on the first day of using the medication.
Indications and contraindications
According to the instructions for use, "Sonizin" is recommended to eliminate dysuria, which is associated with benign prostatic hyperplasia. The drug is contraindicated in people with individual intolerance to the substances of the drug. Additional restrictions are:
- Hypotension (decrease in blood pressure by more than 20 percent).
- Severe illnesses.
- Kidney disease.
Instructions for use
"Sonizin" must be taken orally, preferably at the same time, after meals, with water. In order not to interfere with the release of the active ingredient, the capsule must not be chewed. The recommended dosage is 1 capsule per day. The cost of the drug varies from 400 to 550 rubles.
Side effects
Like any other drug, "Sonizin" is capable of provoking unwanted reactions:
- Nausea.
- Constipation.
- Diarrhea.
- Gagging.
- Asthenia (a painful condition that is manifested by increased fatigue).
- Dizziness.
- Migraine (a neurological disease, the most common and characteristic symptom of which is episodic or regular severe pain).
- Sleep disorders.
- Heartbeat.
- Tachycardia
- Orthostatic hypotension(a clinical syndrome that is characterized by a violation of the body's ability to maintain a normal level of blood pressure in an upright position).
- Decreased libido (psychic energy, including sexual desires).
- Retrograde ejaculation (an ejaculation disorder characterized by abnormal passage of semen).
- Angioneurotic edema (acute condition, which is characterized by the rapid appearance of swelling of the mucous cavity, as well as subcutaneous tissue and the skin itself).
- Skin rashes.
- Itching.
- Rhinitis (runny nose).
- Pain in the back.
To restore blood pressure and stabilize the heart rate, the patient should be laid down. In this case, cardiotropic therapy is recommended. Monitor kidney function and provide general supportive care.
If unpleasant symptoms persist, volume-replacing and vasoconstrictive drugs will be required. To prevent further absorption of the active substance, gastric lavage may be prescribed, as well as the use of enterosorbents, activated charcoal.
Analogues of "Sonizin"
List of substitutes:
- "Hyperprost".
- "Glancin".
- "Tamsulon".
- "Tamselin".
- "Omnic".
- "Fokushin".
- "Tamsulosin".
- "Tulosin".
- "Proflosin".
Before replacement"Sonizina" analogue should consult a doctor to rule out contraindications.
Omnic
The active ingredient is tamsulosin hydrochloride. Additional substances are:
- cellulose;
- polysorbate 80;
- triacetin;
- titanium dioxide;
- indigotine;
- iron oxide yellow;
- gelatin;
- talc;
- calcium stearate;
- sodium s alt of lauryl sulfuric acid.
Before you start using drugs, you need to clarify the diagnosis and exclude the presence of other pathologies in the body. With caution, the drug "Omnic" is used in the presence of a history of orthostatic hypotension.
From the instructions for use to the analogue "Sonizin" it is known that the alpha-blocker does not have a detrimental effect on the ability to drive a car or perform work that requires increased attention and speed of psychomotor reactions. The price of "Omnik" ranges from 350 to 2800 rubles.
Hyperprost
The drug should not be used in case of hypersensitivity to any of its components. Caution during therapy should be observed in the following situations:
- chronic kidney disease;
- severe liver disease;
- low blood pressure.
According to the instructions for the analogue of "Sonizin", the composition of the medication includes:
- tamsulosin hydrochloride;
- ethylcellulose;
- sucrose;
- mannitol;
- povidone;
- indigocarmine;
- gelatin;
- water;
- titanium dioxide.
According to the feedback from patients and the opinion of doctors, the medication can only be used after a complete examination. When the first symptoms of orthostatic hypotension occur - weakness, as well as dizziness - a person must be laid down or seated. During therapy, care should be taken when performing work with potentially dangerous consequences.
Glancin
After oral use, the active substance is well absorbed in the intestine. The drug has almost 100% bioavailability. If you take "Glansin" during a meal, the absorption process slows down somewhat. Therefore, it is recommended to take the drug before meals.
Composition of the drug:
- tamsulosin hydrochloride pellets;
- sugar grains;
- macrogoal;
- isobutenoic acid;
- acrylic acid ethyl ester;
- ethylcellulose.
Before using the drug, you should be examined to exclude other diseases that may manifest the same signs. Before starting therapy and periodically during treatment, it is necessary to constantly conduct an examination.
Special care while taking the drug must be observed in persons with symptoms of its development, the patient should sit or lie down andremain in this position until the unpleasant symptoms disappear completely.
Due to the likelihood of small pupil syndrome, if you need surgery for glaucoma and cataracts, you need to stop taking the medication in one to two weeks.
In addition, it is important to inform the surgeon about the use of the medicine so that he takes this into account when preparing and performing the operation. The cost of the medicine varies from 370 to 1,200 rubles.
Proflosin
Alpha1-blocker, which is used for urinary problems that are provoked by benign prostatic hyperplasia. This is an analogue of "Sonizin" (a photo of the drug is presented above).
Ingredients:
- fokushin;
- acrylic acid ethyl ester;
- isobutenoic acid;
- cellulose;
- talc;
- triethylcitrate.
After taking the drug, the absorption of tamsulosin from the stomach and intestines is carried out almost completely and quickly. The rate of its absorption decreases with the simultaneous intake of food. The maximum blood level after using a single dose of the drug is reached after about 6 hours.
If dizziness or weakness occurs, which may be the first signs of orthostatic hypotension, the patient should sit or lie down.
The appearance of Quincke's edema in a person when using an analogue of the drug "Sonizin" indicates an increased sensitivity toactive substance. Therefore, therapy must be stopped immediately, re-use of "Proflosin" in this situation is prohibited.
In cataract surgery, there is a possibility of atonic iris syndrome in patients who use this medication. Therefore, it is important to warn the doctor about the use of Proflosin so that he takes this fact into account. The cost of the medicine varies from 400 to 1,300 rubles.
Tamsulosin
Medication that is designed to eliminate urination disorders in benign prostatic hypertrophy. This is a cheap analogue of Sonizin, its cost varies from 400 to 900 rubles.
The medicine contains:
- tamsulosin;
- 2-methylpropenoic acid;
- acrylic acid ethyl ester;
- triethyl citrate;
- talc;
- water.
Before using "Tamsulosin" it is important to make sure that there are no other diseases that can provoke the same unpleasant symptoms. Certain examinations are also carried out before the start of therapy.
Tulozin
Alpha-blocker that competitively blocks postsynaptic adrenoreceptors located in the smooth muscles of the bladder neck and prostate. From the instructions and reviews to the analogue of "Sonizin" it is known that the structure of the drug includes the following components:
- tamsulosin;
- cellulose;
- calcium s alt and stearic acid;
- acrylic acid ethyl ester;
- 2-methyl-2-propenoic acid.
With the help of the action of the active component, the tone of the smooth muscles of the prostate gland, as well as the neck of the bladder, is lowered, the functioning of the detrusor is improved. As a result of these effects, the drug provides relief from signs of irritation and obstruction.
According to reviews, the pharmacological effect of the drug is observed, as a rule, two weeks after the start of therapy, but in some people, a decrease in the severity of symptoms may be observed after the first dose. The cost of "Tulozin" varies from 500 to 600 rubles. What other drugs are included in the review of analogues "Sonizin"?
Fokushin
A drug that is aimed at eliminating urinary disorders caused by benign prostatic hyperplasia.
Drug structure:
- tamsulosin hydrochloride;
- gelatin;
- cellulose;
- silica;
- dibutylsebacate;
- talc.
The therapeutic effect of the drug is based on its ability to block postsynaptic alpha-adrenergic receptors located in the bladder neck, prostate smooth muscle.
In addition, the drug has the ability to block alpha1D adrenoreceptors, which are usually located in the body of the bladder. Subsequently occursa decrease in the tone of the smooth muscles of the above-mentioned organs, as well as an improvement in the functioning of the muscles of the urethra. This, in turn, entails a reduction in the signs of irritation and obstruction provoked by prostatic hyperplasia.
According to the annotation to "Focusin", pharmacological effects from the use of the drug occur within two weeks from the start of use. In rare situations, there is a decrease in the severity of symptoms after the first dosage. The price of the medicine ranges from 400 to 1,400 rubles.
Zokson
An antihypertensive drug is also effective in benign prostatic hyperplasia as a drug that reduces urinary disorders.
"Zokson" is another name for the analogue of "Sonizin". Includes:
- doxazosin mesylate;
- granulated pulp;
- lactose;
- silica colloid;
- sodium carboxymethyl starch;
- magnesium s alt of stearic acid;
- sodium s alt of lauryl sulfuric acid.
When using "Zokson" in patients with benign prostatic hyperplasia, urodynamic parameters improve and the manifestations of signs of the disease decrease. The positive effect of the drug is due to the blockade of alpha1-adrenergic receptors, which are located in the stroma of the prostate and in the region of the bladder neck.
Subsequently, the decrease in total peripheral vascular resistance is significantly reducedblood pressure. A clinically significant antihypertensive effect is achieved with the appointment of "Zokson" once a day and lasts for an hour.
In this case, blood pressure decreases gradually, and the maximum is observed after 2-6 hours after taking the pills. The drug has a beneficial effect on the blood lipid profile, greatly reducing the level of cholesterol and triglycerides, thereby helping to reduce the possibility of cardiac ischemia.
"Zokson" reduces hypertrophy of the left ventricle of the heart, inhibits the production of platelets and reduces the tendency to thrombosis. The drug can be used in patients with diabetes mellitus, as well as in people with gout, bronchial asthma, since it does not adversely affect metabolism.
The bioavailability of the drug is seventy percent. With violations of the functioning of the liver and the use of drugs that change the liver metabolism. Its elimination from the blood is considered biphasic, with a terminal half-life of 22 hours.
Conclusion
In most situations, drug reviews confirm that the patient's condition improves after therapy. Men who have been diagnosed with prostate disease say they are on full therapy with these medications.
Such pharmacological treatment is effective, but only for a certain time. After stopping therapy, all negative symptoms return again. Start using similar alpha-blockersshould only be prescribed by a medical professional.
