Unfortunately, no one is immune from injuries. Some injuries are so severe that it is impossible to do without the help of a specialist. The doctor will not only help to avoid the inflammatory process, but also save the patient from unbearable pain. In case of serious injuries and after surgical interventions, the drug "Artrosilene" is often used. Injections are prescribed in the most difficult cases. In pharmacies, you can find medicine in the form of a solution, suppositories and tablets.
Composition of the drug
The drug belongs to the category of non-steroidal anti-inflammatory drugs. Ketoprofen lysine s alt acts as the main active ingredient. Additionally, substances such as sodium hydroxide, citric acid, and purified water are used. The drug is supplied to pharmacies in glass ampoules packed in cardboard boxes.
Has a complex effect means "Artrozilen". Injections help relieve fever, remove inflammation, and also produce an analgesic effect. The patient feels relief already in the first days of therapy. Ketoprofen lysine s alt isfast-dissolving compound. Due to this, during the treatment process, the patient practically does not irritate the gastrointestinal tract. The main active ingredient does not affect articular cartilage either. During the treatment, the patient does not feel morning stiffness and swelling of the joints.
Pharmacokinetics
During oral administration, the capsules of the drug are quickly absorbed from the gastrointestinal tract. The maximum bioavailability can be 80% and is achieved after 4-5 hours. Bioavailability indicators directly depend on the dose that the patient takes. Experts do not recommend taking the medicine with food. This contributes to a significant decrease in the bioavailability of the main active ingredient.
When administered intravenously or intramuscularly, the drug is also rapidly absorbed. The maximum plasma concentration can be reached after 40 minutes. The therapeutic effect is maintained throughout the day. More than 95% of the main active ingredient binds to plasma proteins. Ketoprofen lysine s alt easily penetrates through the walls of blood vessels and is distributed in tissues and organs. Thanks to this, the analgesic effect is achieved fairly quickly.
Indications
The instructions for use attached to the preparation "Artrosilene" should first be studied by those who were injured. Injections may not be for everyone. The drug belongs to the category of potent and can be used for fairly serious injuries or as a prophylactic drug after surgery.interventions.
Short-term treatment of pain syndrome is acceptable for diseases of the musculoskeletal system. At the same time, they are prescribed only as part of the complex therapy "Artrosilen" (injections). Reviews show that the drug partially eliminates inflammation, and also relieves pain. To eliminate the cause of the disease, it is necessary to use special medications of a narrow profile.
You should not use the drug "Artrosilen" without consulting a doctor. Injections also have their contraindications. In addition, specialists do not recommend a potent remedy for minor injuries.
Contraindications
Must be studied before using the drug "Artrosilene" instructions for use. Injections are not for everyone. So, a potent drug is not prescribed to minors. Cannot be used by women during pregnancy and lactation. There are also a number of serious contraindications related to the patient's state of he alth. If a person is diagnosed with peptic ulcer of the stomach and duodenum, bleeding disorders, diverticulitis or chronic renal failure, it is better to choose another medication.
As practice shows, in most cases it is in the hospital that the treatment with the drug "Artrosilene" is carried out. Injections can be prescribed only after a complete examination of a sick person and a diagnosis. A qualified specialist should initially study the patient's medical history,to exclude the possible development of side effects and other negative reactions, not forgetting the existing contraindications. The medicine is prescribed with caution to patients suffering from diabetes mellitus, liver failure, chronic heart failure.
Special Instructions
Before starting treatment, the specialist must check the picture of peripheral blood, as well as the functional state of the liver and kidneys. It should be borne in mind that taking Artrosilen can mask the presence of an infectious disease. This is due to the fact that the medicine removes the pain syndrome, the patient's well-being improves significantly. At the same time, the drug has no effect on the development of infection.
As the reviews show, at the beginning of therapy, Artrosilene causes rather unpleasant sensations. The injections are painful, and therefore patients are quite difficult to tolerate the procedure, although there are exceptions. Medicine knows cases of loss of consciousness during manipulations. Experts recommend giving injections in a supine position. More unpleasant are intramuscular injections. However, the pain passes rather quickly.
Dosage
At the initial stage, the drug is prescribed intravenously or intramuscularly at 160 mg per day (1 ampoule). In the most difficult cases, the daily rate can be doubled. The maximum daily dose should not exceed two ampoules. Patients over 65 years of age are not prescribed more than 160 mg per day. The same rule applies to people with liver failure. How long should I take "Artrosilen"?Injections are given no more than three days. Further, experts recommend switching to the use of suppositories or tablets. Injections are made only in a hospital setting.
You can prolong the duration of the drug with the help of infusions, when the drug is administered intravenously for half an hour. The drug can be prepared on the basis of a solution of sodium chloride, an aqueous solution of levulose, a solution of dextose.
Procedural sisters say that people tolerate the introduction of the drug "Artrosilene" differently. The injections are painful. As already mentioned, sometimes patients even for a short moment lost consciousness during the procedure. According to some patients, the pain syndrome is not so pronounced, although, of course, the sensations are rather unpleasant. If you take injections in a supine position, the procedure is tolerated a little easier.
Overdose
It is necessary to strictly observe the dosage using "Artrosilene" (injections). Reviews of experts show that improper use of the drug can lead to a deterioration in the patient's well-being. There are unpleasant symptoms from the gastrointestinal tract. The patient may experience nausea, stomach pain, dizziness.
In case of overdose, symptomatic therapy is carried out. The doctor must necessarily monitor the respiratory and cardiovascular systems.
Side effects
May provoke the development of side effects "Artrosilene" (injections). Analogues can also contribute to the appearance of unpleasant symptoms. So use them fortreatment of a specific pathology should be done only after consulting a doctor. On the part of the digestive system, side effects can manifest themselves in the form of abdominal pain, stomatitis, increased activity of liver enzymes, erosive lesions of the gastrointestinal tract.
Dizziness, tremor of the extremities, vertigo, night sleep disturbances were observed from the side of the central nervous system. In some cases, visual impairment occurs. It is worth remembering that the drug "Artrosilene" (injections) and alcohol are incompatible. Alcohol primarily contributes to the development of negative reactions. The most difficult are the side effects from the cardiovascular system. Patients may experience chest pain, tachycardia, syncope. Hypertension often develops.
Drug Interactions
Significantly increase the metabolism of ketoprofen inducers of microsomal oxidation in the liver, such as phenytoin, ethanol, rifampicin, barbiturates. Against the background of taking the drug "Artrozilene", the effectiveness of uricosuric drugs may be reduced. It is not recommended to combine the drug with antihypertensive drugs, as well as diuretics.
With other non-steroidal anti-inflammatory drugs, you need to carefully combine injections "Artrosilen". The instruction states that such an interaction can lead to the development of stomach ulcers, as well as gastrointestinal bleeding. There is a high chance of kidney dysfunction.
Prescribed with cautionpeople suffering from diabetes. With the simultaneous use of ketoprofen and insulin, the concentration of the latter in the blood may increase. Diabetics need to recalculate the dose before starting treatment.
Medication reviews
You can hear good reviews about the drug "Artrosilen" (injections). Intramuscularly, the drug is administered only in a hospital setting. Here, specialists monitor the patient's condition. Therefore, side effects develop quite rarely. Patients complain only of discomfort during injections. However, according to them, the pain passes quickly enough. Suppositories and capsules "Artrozilen" have also proven themselves well. In this form, the drug can be used at home. You must first consult with your doctor.
Doctors note that side effects develop most often if the correct dosage is not observed. Doctors emphasize that people with kidney failure and diabetes should take the medicine with extreme caution.
If it was not possible to find the right drug in a pharmacy, a specialist will always be able to find a high-quality analogue. The most popular means that can replace the drug "Artrosilene" will be described below.
Ketonal
The drug belongs to the group of non-steroidal anti-inflammatory drugs. The solution can be used for intravenous or intramuscular administration. The main component is ketoprofen. Additionally, the composition of the drug includes substances such asethanol, propylene glycol, benzyl alcohol, purified water. The drug has an analgesic and anti-inflammatory effect. A drug is prescribed to eliminate pain in diseases such as gout, sciatica, osteoarthritis. Often the drug is used in oncology.
The drug has its contraindications, as well as the drug "Artrosilen". Instructions for use (injections), expert reviews, dosage - all this information should be studied before starting treatment. It is unacceptable to use the solution "Ketonal" for bronchial asthma, hemophilia, renal failure. Do not prescribe medicine to women in the first trimester of pregnancy, as well as to patients under 15 years of age.
Artrum
This drug, like the previous ones, is based on ketoprofen. Additionally, agents such as propylene glycol, benzyl alcohol, sodium hydroxide, purified water are used. The drug is supplied to pharmacies in glass ampoules packed in cardboard boxes. The medicine can be prescribed for rheumatoid arthritis, osteoarthritis, sciatica. The drug is used in neurology and oncology as an aid to eliminate pain. The solution is not prescribed to minor patients.
Flamax
This non-steroidal anti-inflammatory drug is available as a solution and capsules. The main active ingredient is also ketoprofen. Additionally, substances such as sodium hydroxide, benzyl alcohol, propylene glycol,purified water. Means "Flamaks" is used to eliminate pain in migraines, inflammatory processes of the pelvic organs. The drug can be used in dentistry after surgical interventions.
Flamax solution can cause discomfort during injection, as well as Artrosilene (injections). Painful or not, these injections depend on the individual characteristics of the patient's body. However, any unpleasant symptoms disappear within a few minutes after the administration of the drug.
