Various infectious diseases and epidemics are constantly breaking out in the world. Some of them are vaccinated, while others are not. Children are especially affected by such diseases.
Influenza outbreaks are common, so in recent years, scientists have thrown their efforts into creating drugs to prevent and combat this disease. One of the newest drugs is the Grippol Plus vaccine. For children, the reviews confirm this, and for adults it helps a lot during the epidemic.
Description
Grippol Plus is a new polymer-subunit trivalent inactivated vaccine, a third-generation drug that is aimed at preventing influenza when an epidemic occurs. It consists of surface protective antigens of hemagglutinin and neuraminidase, which are isolated by purification of influenza A and B viruses. It is a clear liquid, completely colorless or slightly yellowish, slightly opalescent.
Every year, scientists receive fresh official data on the emergence of new strains of influenza and forecastsabout which ones are most likely to appear in a particular region. With this data, experts are modernizing the vaccine by changing the antigenic composition in such a way that its components act as efficiently as possible.
The drug belongs to the pharmacological group of vaccines, sera, phages and toxoids in combinations and to the ICD-10 nosological classification.
"Grippol plus": composition and release form
The vaccine is manufactured in the Netherlands by Abbott Biologicals B. V. and contains hemagglutinin of epidemically relevant strains of influenza viruses:
- subtype A (H1N1) - in the amount of 5 mcg;
- subtype A (H3N2) - in the amount of 5 mcg;
- Type B - 5mcg.
Also, the drug includes the immunoadjuvant polyoxidonium - 500 mcg.
"Grippol plus", the price of which is currently 150-170 rubles. for one dose syringe, is a suspension for intramuscular and deep subcutaneous injection in the amount of 0.5 ml (adults and children over 3 years old), which corresponds to one dose that a disposable syringe holds.
A carton pack consists of one package, which in turn contains a single syringe, packed in a contoured honeycomb shape.
The drug is recognized as fit for use within one year after production.
Pharmacological action
After the planned vaccine "Grippol Plus" is administered to children, the reviews of experts confirm this, its effectpersists throughout the year. However, this applies to all groups of the population - both adults and the elderly. As a rule, the effect should be expected after eight to twelve days after the introduction of the vaccine, so it is important to take preventive measures even before the start of the epidemic.
Grippol plus (Komarovsky, a well-known children's doctor, also focuses on this) provides effective high-level protection for about 90% of patients. Therefore, do not forget that the risk of contracting the flu still remains, and this should not be neglected. It is worth taking care of yourself, taking vitamins, since the vaccine only specifically stimulates the human immune system with the help of polyoxidonium, increasing the stability of antigens, increasing resistance and resistance to various infections. Due to the increase in immunological memory, it is possible to subsequently significantly reduce the vaccination doses of antigens.
Drug Benefits
This vaccine has a number of advantages:
1. Presence of highly effective protective properties:
- the statement is true for patients of any age;
- duration of protective functions throughout the epidemiological season;
- re-introduction of the vaccine is performed only when new varieties of viruses appear (by this time the composition of the drug changes accordingly);
- possibility of vaccination during an already developing epidemic due to the rapid immune response of the body to the vaccine.
2. Usage Safety:
- Grippol Plus vaccine, instructions for use clearly indicate this, does not contain preservatives with mercury and therefore is indicated even for pregnant women;
- Due to the three times reduced content of antigens, the vaccine has a low protein load, which does not reduce the effectiveness of the drug.
3. High quality vaccine:
- manufactured according to all international standards;
- comprises a water-soluble immunoadjuvant that has no analogues in the world;
- high level antigen purification.
4. Easy and convenient use:
- sterility is ensured by an individual syringe dose;
- painless insertion due to atraumatic needle.
Indications for use
During the period when the influenza epidemic begins to develop, the Grippol Plus remedy, the price of which is rather low, is recommended:
- Transport, trade workers, military, working in the educational, social and medical fields, as well as other categories, one way or another connected with communication with people.
- People who have a weakened immune system, including those infected with HIV.
- Patients with somatic diseases: allergies, anemia, bronchial asthma, metabolic disorders, kidney diseases and others.
- Older people over 60, preschoolers over 3 years of age and schoolchildren.
- Children and adults prone to acute respiratorydiseases.
- Suffering from disorders of the central nervous and cardiovascular system.
- Patients with autoimmune diseases.
Contraindications
Like all medications, there are pros and cons for Grippol Plus. Doctors do not allow it to be used even if vaccination is necessary during the development of the epidemic, if available:
- acute intestinal diseases;
- SARS with temperature;
- allergic manifestations (to the vaccine);
- exacerbations of chronic diseases;
- chicken protein allergy;
- Individual intolerance to vaccine components.
Possible side effects
When vaccinating against influenza, it is necessary to take into account what side effects the drug "Grippol plus" has. These include:
- neurological disorders;
- neuralgia;
- paresthesia;
- myalgia;
- sore throat;
- rhinitis;
- headaches;
- increased body temperature;
- reddening of the surface of the skin;
- weakness and feeling unwell;
- edema;
- specific allergic reactions.
Adverse symptoms are extremely rare due to the fact that all components of the vaccine are highly purified. Within, as a rule, the above side effects disappear on their own within 1-3 days.
"Grippol plus": instructions for use
Vaccination should be done as follows:
- after keeping the drug until it reaches room temperature, shake the syringe well just before injection;
- after removing the protective sheath, holding the syringe with the needle up, squeeze out the air by slowly pressing the piston;
- injection for adults is performed intramuscularly or deep subcutaneously in the upper third of the shoulder on the outer surface in the region of the deltoid muscle, in children - in the anterior-outer region of the thigh;
- The Grippol Plus vaccine for children (reviews from various experts inform that this is optimal) is administered once at half the dose of the standard volume, and for adults in full.
It is important not to make a mistake with the injection of the drug to a child, therefore, before the injection, half of the contents of the syringe is released out to a special mark designed specifically for such cases.
Patients with immunodeficiency diseases and receiving immunosuppressive therapy are vaccinated twice at half a dose with a one-month break.
Annual vaccination of the population is carried out in the autumn-winter period and during the beginning of the development of the epidemic.
Vaccine reviews
Introduced vaccine "Grippol plus" to children, the reviews of many parents confirm this, in most cases it helps. That, however, does not completely exclude the risk of infection, which is in the range of five to twenty percent of the total number of vaccinated.
Unfortunately, today on the planet there is no one hundred percent effective drug for the insidious influenza virus. Therefore, you can hear negativestatements about "Grippol" from those people who fell ill despite the vaccination.
Many try to choose: "Influvak" or "Grippol plus"? In fact, there is little difference between existing flu drugs, but the latter is more affordable and is said to be more effective.
Special instructions and precautions
Vaccination is allowed for pregnant and lactating women only after consulting a specialist. Most often, vaccinations work safely, problems arise if there are he alth problems. The safest periods are the second and third trimester, it is better to get vaccinated at this time.
Intravenous administration of the drug is prohibited.
In the treatment room where vaccination is carried out, the availability of anti-shock therapy is mandatory. After vaccination, the patient must be under the supervision of a specialist for another half an hour.
On the day of vaccination, the vaccinated person must undergo a medical examination with a mandatory measurement of body temperature, it should not exceed 37.0 °C.
Do not use a drug from a damaged package, with a poorly visible label, if its physical properties have changed, the expiration date has expired or storage rules have been violated.
The medicine should be stored and transported in a light-proof package at a temperature not higher than eight degrees Celsius and not lower than two.
Grippol can be used together with other inactivated vaccines, taking into account various contraindications and injection sites using different syringes.
