It's no secret that we all want to stay young and beautiful for as long as possible. And thanks to the achievements of modern medicine, this is not some kind of impossible desire. A few rejuvenating injections, as people say, - and now the burden of the years has disappeared along with smoothed out wrinkles on the face.
Medications based on botulinum toxin are able to level out the external signs of skin aging for six months after the injection. One of these medicines is Xeomin, a review of which most consumers characterize the drug as highly effective.
Composition of the drug, pharmacodynamics
One bottle of "Xeomin" contains 100 IU of botulinum toxin type A. Sucrose and serum albumin (human) act as additional components. Practical principle of operationof all preparations based on botulinum toxin is based on a temporary blocking of nerve impulses going to the treated muscle, as a result of which it stops contracting and smoothes out.
The drug contains a muscle relaxant (a substance that lowers the tone of skeletal muscles and reduces motor activity up to immobilization), which suppresses the release of acetylcholine, a neurotransmitter, which is the main "actor" in the processes of neuromuscular transmission. After the injection of "Xeomin" (patient reviews of the procedure itself will be discussed below), the movement of ecovesicles is disrupted at the cellular level, the synthesis and release of acetylcholine stops. Within 4-7 days, relaxation of the treated muscle occurs, i.e., deep relaxation, accompanied by the removal of mental stress. The effect will be maintained for up to 4 months.
The drug is produced in the form of a lyophilisate powder. The medicine is packaged in vials (each in a separate package). The sealed vial has a shelf life of 3 years. Already diluted for injection, botulinum toxin can be stored for the next 24 hours under certain temperature conditions: 2-8 degrees Celsius.
Indications for the use of the drug
According to the official instructions for use, Xeomin is prescribed for blepharospasm, atrophic changes in the skin and spastic torticollis.
Blepharospasm is understood as involuntary contractions of the circular muscle of the eye, which, as a rule, lead to persistentspasmodic closure of the eyelids. The drug "Xeomin" reviews of he alth professionals are characterized as an effective tool for the treatment of this problem. The treatment of torticollis (changes in the soft tissues, nerve endings and skeleton of the neck, manifested in the tilt of the head with turning it in the opposite direction), acquired as a result of contraction of the cervical muscles (spastic or reflex torticollis), is being treated with no less positive results.
However, most often this drug, acting mainly on the peripheral nervous system, is used for atrophic changes in the skin of the face around the eyes, nasolabial folds, etc.
Methods of application for various diseases
In order to administer Xeomin injections (patient reviews and expert opinion confirm this), you must have certain qualifications and experience with such medical devices. The number of necessary injections and dosage is determined by the specialist.
In the treatment of blepharospasm, the dose of a single injection is 5 units. Therapy can last up to 12 weeks, during which the total maximum dosage should not exceed 100 IU. Injections are made into the orbicular muscle of the eye, into the lateral part of the orbicular muscle of the eye of the lower eyelid, into the muscular apparatus of the face.
When treating torticollis, the doctor finds out the localization points of pain and determines the place of the procedure. When calculating the dosage, the weight of the patient and the volume of the diseased muscle are taken into account. In most cases, the dose for a single application does not exceed 200 IU.
Major usemedicine found in aesthetic cosmetology. To correct "crow's feet" or small wrinkles, "Xeomin" is injected under the eyes.
Reviews from patients are mostly positive. In addition, the drug is effective for eliminating wrinkles of any direction on the forehead and between the eyebrows, removes radial wrinkles around the mouth and in the décolleté area. In each case, the dosage of the drug is calculated individually for each patient.
Xeomin Benefits
If the decision to conduct botulinum therapy is finally made, patients often face the question of which drug to prefer - Botox or Xeomin. What's better? Reviews of both medicines are both positive and negative.
The main application of "Xeomin" is still more cosmetology, not medicine. The composition of the drug does not contain a protein part, which practically eliminates the likelihood of developing inflammatory processes and allergic manifestations. The smallest molecular weight of all known botulinum toxins allows Xeomin to be applied to the smallest muscles.
Further, the medication does not have to be stored in the cold, which gives the palm to the remedy in question if the following question arises: "Dysport" or "Xeomin" - which is better? Manufacturer's reviews indicate the impossibility of violating efficiency due to deviations in storage conditions ortransportation. Even if the drug is used for a long time, antibodies are not produced in the body. The drug molecules have a minimal ability to diffuse, which eliminates the development of any negative effects from the drug in areas adjacent to the treated areas. For the same reason, the minimum diffusion - the dose required to obtain a positive effect - Xeomin is much less than Botox.
In addition to all of the above, "Xeomin" does not affect the deep layers of facial muscles, which allows the patient to maintain emotional reactions. This advantage is especially valuable for public people.
With regard to finances, it is worth saying that Xeomin is somewhat cheaper than Botox - 250 rubles against 320-330.
Disadvantages of Xeomin
From the negative characteristics, one can single out the fact that the drug is ineffective in the treatment of armpit hyperhidrosis. The reason for this phenomenon lies in weak diffusion. In addition, the analogue of Botox - Xeomin (patient reviews confirm this fact) - gives a stable result for 3-4 months, while Botox itself is effective for six months.
It is also worth mentioning that Xeomin has not yet accumulated a sufficient scientific base (Botox has been more studied in this regard, since it has been used in medicine and cosmetology for a long time).
Contraindications for the use of the drug
Any drug with the simplest formula has contraindications, not to mentionbotulinum toxins. The unique composition of the drug and the ability to use minimal doses leads to the fact that any negative review about Xeomin is drowning in a sea of positive feedback. Nevertheless, the drug has a number of serious contraindications for use.
Do not prescribe it to those patients who suffer from diseases of the nervous and muscular systems, accompanied by muscle weakness (for example, myasthenia gravis). Hypersensitivity to botulinum toxins, malignant neoplasms of any localization, glaucoma are also sufficient grounds for refusing to use this drug.
Naturally, patient reviews about Xeomin will be negative if you do not notify the doctor before the procedure that the person is currently suffering from an acute infectious disease, accompanied by fever, and on this occasion takes any antibacterial or some other medications. The reaction of the body in this case to the introduction of botulinum toxin cannot be predicted at all, but it will be present with a high degree of probability.
It is unacceptable to use Xeomin injections for pregnant women and nursing mothers, patients suffering from any diseases of the blood system, accompanied by its poor coagulability. The procedure should be postponed until better times if any dermatological, inflammatory, purulent skin problems are observed in the area where the injection is to be made. Also, a contraindication is the presence of severe somatic diseases in the patient in the stagedecompensation.
Possible side effects
Reviews of patients about Xeomin, as well as medical workers, speak of the development of adverse reactions to botulinum toxin injections, albeit not often, but taking place. In most cases, this happens either due to a violation of the technique of the procedure by the doctor, or due to the patient's non-compliance with the doctor's recommendations after the injection.
Most often people talk about unpleasant phenomena and sensations in the injection area - bruising, swelling, burning. Perhaps the development of ptosis (omission) of the upper eyelid, sagging tissues, asymmetry of the face. Sometimes you can hear about the development of flu-like symptoms, the appearance of a headache.
As for the doctor's recommendations after the Xeomin injection procedure, negative reviews are often written by patients who neglected the doctor's instructions. You need to know that after the injection you can not massage this place on the skin, apply any cosmetics. It is unacceptable to heat facial tissues (solarium, sauna, bath, etc.) and drink alcohol. In addition, you can not expose yourself to great physical exertion, sleep face down, use certain medicines (for example, antibiotics).
If the medication was used to treat blepharospasm, then the Xeomin remedy (reviews on the drug, reviews on injections) can be negative due to the reasons for the manifestation of a much larger number of side effects. These include dryness of the mucous membrane of the eyeball, lacrimation, paresthesia, lagophthalmos(inability to completely close the eyelids), diplopia (simultaneous vision of two images of the same object, shifted relative to each other horizontally, vertically, diagonally).
Considering the possible negative reactions of the body to the drug "Xeomin" (a review of a small group of patients reported a deterioration in visual perception), it is highly desirable to refrain from performing work after the procedure that requires increased concentration of attention and speed of psychomotor reactions. He alth workers give the same recommendations about driving.
Possible consequences of exceeding the permissible dose
The introduction of excessive doses of "Xeomin" can cause paralysis of muscles located at a sufficient distance from the injection zone. The fact that an overdose has occurred may be indicated by such conditions as asthenia (feeling of impotence, manifested by increased fatigue, mood instability, etc.), diplopia, ptosis. If there are difficulties with swallowing, problems with speech, paralysis of the muscles involved in the process of breathing, with the parallel formation of pneumonia of an aspiration nature, medical care is needed in a hospital setting. In especially severe cases of reaction to "Xeomin" (review in this case, as a rule, left by a specialist), it would be advisable to use intubation, artificial lung ventilation (ALV).
Which do you prefer - Xeomin, Botox or Dysport?
It can be quite difficult to make a choice between Botox and Xeomin. Reviews of experts say that both medicines are made onbased on one botulinum toxin type A. The only difference is that Xeomin is an improved version of Botox. Both drugs have the same principle of action: the main active ingredient blocks the contractile function of the muscle, as a result of which it relaxes.
The principle of the impact of "Dysport" is also very similar to both of the above remedies, but to obtain a significant result, its dose is several times higher: if "Botox" or "Xeomin" is needed for the procedure 5-30 IU, then "Dysport" for injection at the same point - 15-90 units
The essential difference between Xeomin and the other two medicines is the absence of a protein complex in the first. This factor, as mentioned earlier, gives a lot of advantages to this drug over all the others. Here is the possibility of long-term storage without observing strict temperature restrictions, and a very low probability of developing allergic manifestations, and a minimal risk of addiction and decreased sensitivity. The absence of protein compounds allows Xeomin molecules to be attracted more tightly and adhere to the muscle endings, which practically negates the possibility of shifts in the tissues, i.e., the skin at the injection site will not sag.
According to patients and doctors, when choosing a drug for injection, one should also pay attention to the fact how quickly the result becomes noticeable visually and how long it lasts. According to the duration of exposure (about six months), the palm is for Botox, the other two botulinum toxins will work effectively for3-4 months. In terms of the speed of manifestation of the result, Xeomin or Dysport have proven themselves better. Reviews of patients and he alth workers in this matter are the same. The effect will become noticeable after 2-3 days.
Opinion of patients and he althcare workers about the drug
Among consumers, by now there is an opinion that Xeomin has the greatest effect on the mouth, eyes and nose, while Dysport has a better effect on the forehead and bridge of the nose. For some time now, it has been believed that Xeomin is more suitable for young patients, although the drug is also able to solve age-related problems.
Women's opinions are rather ambiguous about Xeomin. Reviews (before and after the injection - many do not see the difference in appearance) of such content can be read from time to time on women's forums in social networks. Although a certain group of patients liked the medication very much. Further, the effect of "Xeomin" lasts 3-4 months, while "Botox" will be effective for at least 6 months.
However, there is another opinion about "Xeomin" - this is the opinion of cosmetologists. This drug has a more gentle effect on the skin, its formula is much softer than that of all previously known medicines of this series. The absence of a protein component minimizes the risk of side effects and allergic reactions, but also significantly reduces the period of effective exposure to the skin. Low diffusion - a guarantee that the drug will not affect neighboring areas of the body and will not affect deep-lying muscles.
In any case, the most correct decision when choosing a drug for botulinum therapy would be to consult a doctor. Only a doctor will assess the state of he alth of his patient, take into account all the associated problems and decide on the use of this or that medication with the lowest risk of developing side effects and allergic manifestations, but with the maximum cosmetic effect possible in terms of duration and attractiveness.
