In the article, we will consider what Papaverine hydrochloride candles help with.
The drug is a drug that effectively fights spasms of smooth muscles of the peritoneum, bronchi, cerebral vessels, kidneys and peripheral vessels.
In addition, this drug relieves the symptoms of angina pectoris, reduces the excitability of the heart muscle, has a sedative and hypotensive effect, slows down conduction inside the heart.
The widespread use of the product is due to the significant efficiency of its use, as well as a high degree of safety for the human body. Due to the second property, the drug is very often prescribed to pregnant patients to eliminate spasms of internal organs.
The drug is produced in different forms, invarious combinations is part of the combined medicines. These are capsules, injection solutions, tablets and suppositories.
Each form of release has its own advantages, which allow to influence the patient's body to a certain extent. "Papaverine" in suppositories is more often used to relieve spasms and suppress pain, especially in the area of the pelvic organs. However, the drug in the form of suppositories is no less effective for eliminating spasms of the gastrointestinal tract, pancreatic ducts and biliary tract. "Papaverine hydrochloride" also helps with a number of other diseases, it is also used for hemorrhoids.
Forms and composition
The medicine "Papaverine hydrochloride" is available in three forms:
- Injection solution, which is a liquid transparent substance, ampoules of 2, 5 and ten milliliters.
- Oral tablets (40 mg) in packs.
- Rectal suppositories - grayish, yellowish or white suppositories with a specific torpedo shape; in one package there are ten candles, each 0.02 grams. Why do we need candles "Papaverine hydrochloride", it is interesting to many.
All forms of release of this drug have the same active ingredient - papaverine hydrochloride. The only difference is only in the excipients that are included in the composition of the drug.
Pills additionally include starch, sucrose and calcium stearate.
Injectable solutions - methionine, disodium edetate and purified water.
Rectal suppositories - solid fat.
The effect of the drug on the body
The main goal for which Papaverine hydrochloride suppositories are prescribed is the elimination of smooth muscle spasms and vasodilation. The drug has a calming effect, allows you to quickly reduce sharply increased blood pressure. In addition, it activates the blood flow to the affected organ, helps to restore the normal rhythm of the heart.
Doctors note the positive effect of the drug on the smooth muscles of many organs of the respiratory, reproductive and urinary systems, intestines and stomach. Papaverine hydrochloride, which is an active ingredient, additionally eliminates pain, stops convulsions. Produced in the form of candles, the drug is very convenient to use.
Rectal administration of suppositories "Papaverine hydrochloride" allows the active ingredient to be absorbed into the blood, due to which it is delivered to the affected area at a high speed. This is what determines the high effectiveness of the drug, almost instantaneous improvement in the patient's condition.
The action of candles "Papaverine hydrochloride" lasts from three and a half to four hours. Then the active component is destroyed and leaves the body with urine.
Indications for the use of suppositories
Suppositories are assigned whenspasms and/or pain in any of the organs listed below:
- uterus and appendages;
- pancreas;
- kidneys and liver;
- lungs and bronchi;
- blood vessels of the brain of the head;
- gall bladder;
- intestines and stomach;
- pelvic organs;
- peripheral vessels.
It is desirable to use suppositories for severe pain due to hemorrhoids. In addition, the drug is successfully used in preparing a person for surgical interventions.
Candles "Papaverine hydrochloride" are often used in their practice by gynecologists and urologists. The drug is one of the inhibitors of phosphodiesterase type 5, or PDE-5, perfectly blocks the action of this enzyme, and therefore can be successfully used to treat male erectile dysfunction or disorders of the female reproductive system.
Not everyone knows where to insert Papaverine hydrochloride suppositories during pregnancy.
Rectal suppositories are also prescribed during this period, suppositories are inserted into the rectum. The active ingredient is not dangerous for the expectant mother, and therefore the drug is most suitable for eliminating pain or spasms associated with changes occurring in her body.
The use of suppositories can be an integral part of complex therapy. The drug relieves pain sensations caused by diseases such as bronchitis, pneumonia, various infections (such asbacterial and viral), asthma.
Drug contraindications
Despite the fact that the use of Papaverine suppositories in most cases is absolutely safe for the patient's body, there are a number of contraindications to their use:
- individual sensitivity or allergic reactions to the active ingredient itself or to suppository excipients;
- glaucoma - intraocular pressure rises; due to the fact that suppositories dilate blood vessels, there may be a significant increase in the negative symptoms of pathology;
- presence of various disorders of cardiac conduction; in such diseases, the drug cannot be used, because it starts the activity of the circulatory system;
- kidney failure.
Candles "Papaverine" are not prescribed for children under six months of age. In addition, the drug is not recommended for elderly patients, as there are age-related changes in their body. When determining the pathology of the thyroid gland, as well as endocrinological disorders associated with a deficiency in the production of adrenal hormones, with craniocerebral injuries, rectal suppositories "Papaverine" should be prescribed especially carefully so as not to harm the patient's body.
Possible side effects
The practice of application shows that suppositories "Papaverine" for the elimination of spasms of smooth muscles in the vast majority of cases are tolerated by patients without significant problems. However, the drug may cause several less pleasant side effects:
- lowering pressure, the use of suppositories for the treatment of patients with normal blood pressure should be dosed correctly;
- strengthened allergic reactions;
- lethargy, fatigue, drowsiness;
- appearance of concentration disorders: this effect is most often associated with improper production of hormones, the signs of which are aggravated after the use of suppositories;
- interruption of the heart rhythm, which occurs most often in the presence of cardiac pathologies;
- vomiting and nausea caused by drug overdose;
- constipation, the appearance of defecation disorders, the cause of their occurrence is the deterioration of intestinal motility during the elimination of spasms;
- excessive sweating, which is a consequence of lowering blood pressure, if there is such a sign, you need to reduce the dosage of suppositories.
Interaction with other drugs
With the simultaneous use of papaverine hydrochloride with the drug "Methyldopa", the hypotensive effect of the latter may decrease.
The effectiveness of the drug "Levopoda" under the influence of "Papaverine" decreases.
As a result of simultaneous use with Alprostadil for the purpose of intracavernous administration, priapism may occur.
When used together with anticholinergic drugs, their main properties can be enhanced.
This confirms the candles "Papaverine hydrochloride"instructions for use.
Overdose
If too much of the drug has been administered, it can lead to intoxication. The main signs of this condition are general weakness, drowsiness and obvious hypotension.
In addition, diplopia may occur, that is, visual impairment, which consists in doubling objects when a person looks at them.
If one or more symptoms of intoxication appear, stop using the drug in the future, after which:
- wash the stomach very thoroughly using a mixture of activated charcoal and milk;
- carry out supportive and symptomatic treatment to increase blood pressure and eliminate disorders.
In order to eliminate priapism, it is necessary to administer injections of adrenaline and phenylephrine in the intracavernous way.
So, how to use Papaverine hydrochloride suppositories during pregnancy?
Use of the drug during pregnancy
It has already been mentioned above that the use of Papaverine suppositories for pregnant women is completely safe. However, despite this, it is better to use them when it is no longer possible to do without treatment.
The use of suppositories "Papaverine" is desirable to reduce uterine hypertonicity. This condition manifests itself as constant muscle contractions, which are ultimately ways to terminate the pregnancy. The medicine helps to minimize the risks. In addition, its calming effect allows a woman to be balanced, eliminates stress,which are dangerous for the unborn baby.
Statistics reflect that the use of rectal suppositories "Papaverine hydrochloride" during pregnancy only in exceptional cases can harm the body of the expectant mother. Often there are such side symptoms as increased toxicosis in the first or second trimesters or short-term defecation disorders. But they can be easily de alt with if you adjust your diet.
To reduce the harmful effects on the body, the specialist must correctly calculate the dosage of the agent. If under normal conditions suppositories can be used 2-3 times a day, then it is better for a pregnant woman to use them no more than 1-2 times in two days. It must be remembered that in any case, self-medication is prohibited. Before using suppositories, it is imperative to consult a gynecologist who will advise the patient on the dosage and advisability of taking the drug.
Due to the safe effect on the body, candles can be administered to a woman at any time during pregnancy.
It all depends on the characteristics of the pregnancy and on the situation in each particular case of the patient.
Special Instructions
The use of candles "Papaverine hydrochloride" requires caution when managing numerous mechanisms, driving vehicles, during activities that require accelerated reactions, psychomotor skills and increased concentration.
If you violate the therapeutic course and dosage, you can cause violationsheart rate, low blood pressure and extreme drowsiness.
Instructions for candles "Papaverine hydrochloride" must be strictly observed.
Analogues
If it is impossible to use original candles, an effective analogue is selected. Among the medicines that can replace the drug, taking into account the influence and purpose, you need to list: "No-Shpa Forte" and "No-Shpa"; "Drotaverine"; Spasmolysin.
Before choosing the best option, it is advisable to consult a specialist.
Reviews on candles "Papaverine hydrochloride"
Suppositories, due to the minimum number of undesirable effects, affordable cost and high efficiency, receive a lot of positive feedback from patients.
If a person has their own experience of using the drug, it is necessary to leave a review on the forums and share your impressions with other Internet users.
Patients who used suppositories note a strong antispasmodic effect, normalization of blood pressure and a favorable improvement in the state of the nervous system.
According to reviews, candles "Papaverine hydrochloride" during pregnancy are absolutely safe for the woman and the unborn baby.
Conclusion
Thus, the drug "Papaverine hydrochloride" is produced in three forms such as injection solution, tablets and suppositories.
Its main purpose is to eliminate spasms of smooth muscles of the gastrointestin altract, vessels and bronchi. In addition, it is used in the complex treatment of angina pectoris.
It is forbidden to use this drug for children under one year of age, elderly patients and those who have individual intolerance to the active ingredient and severe kidney failure.
The use of suppositories "Papaverine hydrochloride" is possible during pregnancy, but this should be done under the strict supervision of a doctor and not self-medicate.
