Drug "Niacin" instructions for use characterizes as a powerful tool for lowering the amount of cholesterol in the blood. It has several forms and can be used for the treatment and prevention of various diseases.
What is this?
Drug "Niacin" instructions for use defines as a lipid-lowering and vitamin remedy. This vitamin has several names: nicotinic acid, B3 and PP. This substance received its last name from this list because it prevents the development of such a disease as pellagra (when the skin becomes rough and various inflammatory lesions of the mucous membrane of the tongue and mouth occur, atrophy of the mucous membranes of the gastrointestinal tract).
Vitamin PP is naturally found in the following foods: liver, rye bread, kidney, pineapple and buckwheat flour.
The drug "Niacin" is a white crystalline powder that has no smell. It dissolves well in high temperature water.
Vitamin B3 has two forms:
- nicotinamide;
- nicotinic acid.
The drug "Niacin" is available in tablets or capsules. Store this vitamin at room temperature, but not higher than 25 degrees Celsius, always in a dry place.
Niacin medication is good for about three years. The price of the drug in tablet form is 23 rubles. Means "Niacin-Vial" in the form of a solution for injection costs 65 rubles.
Pharmacological action of vitamin B3
The healing properties of "Niacin" are in its following abilities:
- takes an active part in controlling the amount of sugar in the blood;
- contributes to the normal functioning of the organs of the digestive system;
- beneficial effect on nerves and central nervous system;
- lowers the level of "bad" cholesterol in the blood;
- improves microcirculation;
- eliminates the risk of cardiovascular disease;
- is an active participant in redox processes;
- promotes cartilage repair;
- has anti-inflammatory effect;
- normalizes the concentration of lipoproteins in the blood;
- expands small vessels;
- raises the fibrinolytic activity of the blood;
- promotes the secretion of juice in the stomach;
- beneficial effect on tissue respiration;
- cleanses vessels from dense lipoproteins;
- lowers blood pressure.
In addition, it synthesizes energy from carbohydrates. Vitamin PP is also necessary for protein metabolism and the synthesis of genetic material.
Indications for the use of vitamin B3
The drug "Niacin" instructions for use recommends using in the following diseases and situations:
- avitaminosis and hypovitaminosis PP: unbalanced and malnutrition, pellagra, rapid weight loss, Hartnup's disease (when some amino acids, such as tryptophan, are not absorbed);
- diseases of the gastrointestinal tract: Crohn's disease, trophic sprue, celiac disease, persistent diarrhea, colitis, gastritis, enterocolitis;
- liver problems (acute and chronic hepatitis);
- prolonged fever;
- hyperthyroidism;
- oncology;
- chronic infections;
- prolonged and regular stress;
- hyperlipidemia;
- neuritis of the facial nerve;
- ischemic cerebral circulation disorders;
- vasospasm;
- diabetes;
- microangiopathy;
- spasm of bile ducts;
- trophic ulcers;
- arthritis;
- disorders of the nervous system (schizophrenia, depression, decreased attention);
- alcoholism;
- osteoarthritis.
In case of multiple pregnancy, it is indicated to use the drug "Niacin". B3 is also useful for women during lactation.
Interestingly, the above substance is indicated for people who suffer from photodermatosis (when the skin does not tolerate sunlight well).
Nicotinic acid deficiency
Dailythe need for B3 is 16 mg for men, and only 14 mg for women. If a person does not get enough of the above vitamin, the following he alth problems may occur:
- indigestion;
- regular insomnia;
- headaches;
- lack of appetite;
- pain in limbs;
- frequent dizziness.
Also, experts note that with hypovitaminosis B3 there are memory lapses and skin problems (cracking, inflammation).
Drug "Niacin": instructions for use
This remedy is recommended to be taken as follows:
- adults - maximum 100 mg per day (20-50 mg 2-3 times);
- children - 5-30 mg (every 16 or 8 hours).
If pellagra prophylaxis is being carried out, the drug is prescribed for adults from 15 to 25 mg per day. Slightly lower doses are indicated for small patients: 5 to 20 mg per day.
It is important to monitor liver function when a patient is taking Niacin. Vitamin B3 is able to influence this organ. Long-term use can cause serious liver he alth problems.
Vitamin B3 warnings
Drug "Niacin" instructions for use recommends using as follows: during a meal or with milk to reduce the risk of stomach irritation.
It should be noted that therapeuticdoses of vitamin B3 can cause flushing of the face. This is a safe phenomenon.
Some recommendations for taking the drug:
- Respect the indicated doses.
- Niacin is not taken concomitantly with other medications.
- It is strictly forbidden to use therapeutic doses of the vitamin to pregnant women.
- When taking more than 1000 mg of a vitamin per day, it is important to take tests to determine the level of liver enzymes every three months.
- It is not recommended to use the above remedy without prior consultation with an experienced specialist.
It should be noted that if the patient is taking psychotropic medications, Niacin can only be prescribed after the doctor's permission.
Contraindications
Vitamin B3 orally is not recommended for diseases and conditions such as:
- hypersensitivity;
- gastric ulcer;
- duodenal ulcer.
The drug "Niacin" is contraindicated for parenteral use in severe arterial hypertension, atherosclerosis, gout, hyperuricemia, children.
Vitamin B3 may cause some side effects like:
- from the side of the heart and its system: tingling and burning sensation, flushing of the skin of the face;
- from the nerves and their system: dizziness, paresthesia;
- from the gastrointestinal tract: fatty liver;
- allergy;
- from the side of metabolism:hyperuricemia, increase in the amount of AST, alkaline phosphatase, LHD in the blood.
In addition, the drug "Niacin" instructions for use recommends taking with caution in the following conditions:
- liver failure;
- arterial hypotension;
- glaucoma;
- in the phase of exacerbation of gastric ulcer;
- pancreatitis.
Vitamin B3 is a powerful remedy against various serious diseases, including osteochondrosis, diabetes and pellagra. It is not recommended to use the above remedy on your own without a doctor's prescription, since it has a number of contraindications and side effects. To increase the level of vitamin B3 in the body, you can enrich the diet with foods such as pineapples, liver, kidneys, or products made from buckwheat.
