What can replace a drug like "Magnesium Orotat"? Analogues of this tool are listed below. Also, the materials of the article provide information about the price of the mentioned medication, its properties and methods of application.
Form, description, composition
Magnesium Orotate is produced in the form of white tablets, round and flat, as well as with a notch on one side and beveled on both sides.
What is in this medicine? Magnesium orotate dihydrate is its main substance. In addition to it, the drug in question includes auxiliary ingredients in the form of carmellose sodium, colloidal silicon dioxide, microcrystalline cellulose, corn starch, povidone K30, sodium cyclamate, lactose monohydrate, talc and magnesium stearate.
This product goes on sale in blisters, which are packed in cardboard packs.
Pharmacology
What is Magnesium Orotat? The instruction says that this is a magnesium preparation. As you know, the mentioned substance is the most important macronutrient. It is essential for the human body toproviding many energy processes that are involved in the metabolism of fats, proteins, nucleic acids and carbohydrates.
It should also be noted that the trace element in question affects neuromuscular excitation, thereby inhibiting neuromuscular transmission.
Magnesium is a natural physiological antagonist of such an element as calcium. It controls the normal functioning of myocardial cells, and is also involved in the regulation of its contractile function.
In stressful situations, free ionized magnesium is excreted from the body in increased quantities, and its additional intake increases resistance to stress.
Magnesium deficiency
The drug "Magnesium Orotat" is designed to compensate for the deficiency of the most important trace element in the body. The lack of this substance contributes to the development of neuromuscular disorders (including convulsions, increased sensory and motor excitability, paresthesia), cardiovascular diseases (including tachycardia, ventricular extrasystole, hypersensitivity to cardiac glycosides) and psychological changes (confusion, depression and hallucinations).). It should also be noted that during pregnancy, magnesium deficiency increases the risk of preterm labor and toxicosis.
It cannot be said that s alts of orotic acid take an active part in the metabolic process. They are also necessary for the manifestation of the action of magnesium and its fixation on ATP in cells.
Kinetics
After taking a single dose of Magnesium Orotat, approximately 35-40% is absorbed into the bloodstream. At the same time, hypomagnesemia stimulates the absorption of magnesium ions, and the presence of orotic acid s alts significantly improves this process.
Magnesium is excreted from the body through the kidneys. With a deficiency of this element, its excretion decreases, and with an excess, it increases.
Indications
Under what conditions can a patient be prescribed Magnesium Orotat? According to experts, this remedy should be taken when:
- atherosclerosis;
- cardiac arrhythmias, including ventricular arrhythmias in people with digitalis intoxication;
- arteritis;
- angina;
- acute myocardial infarction (to prevent arrhythmias);
- dyslipoproteinemia;
- alcoholism, state of withdrawal syndrome;
- cachexia.
It should also be noted that Magnesium Orotat is very often recommended for those whose diet is low in protein, as well as low in calories.
The agent under consideration is actively used to compensate for the lack of magnesium. Typically, such a deficiency is observed during breastfeeding and pregnancy, as well as with hyperthyroidism, hypercalcemia, hyperaldosteronism, reduced intake and absorption of the element, its increased excretion from the body, which is associated with impaired kidney function, chronic diarrhea, and so on.
Contraindications
Magnesium is contraindicated in conditions such as:
- hypersensitivity;
- impaired kidney function;
- chronic and acute liver disease;
- urolithiasis, in which the appearance of magnesium-calcium and phosphate stones is observed;
- AV condition and sinoatrial blockade.
The drug "Magnerot": instructions for use
The price of this product will be listed below.
According to the instructions, the drug in question is intended for oral administration. To greatly increase the effectiveness of this medication, it is recommended to take it 60 minutes before a meal. Tablets should be taken with plenty of liquid.
The duration of a conservative course of therapy should be determined by the attending physician in each individual case. Although the instructions also indicate the general scheme of reception.
At the very beginning of the treatment of magnesium deficiency, experts recommend using two tablets of the drug three times a day (for a week). After that, the dosage is reduced to one tablet at a time.
The maximum daily dose of this remedy is 3000 mg (i.e. 6 tablets).
People suffering from night cramps, this drug is usually prescribed in the amount of 2-3 tablets at bedtime (one time).
Side effects
What side effects can Magnesium Orotate cause? Consumer reviews claim that this remedy is well tolerated by them. Although atSelf-administration of the drug in large doses is still possible dyspeptic disorders of the gastrointestinal tract, which are manifested by instability of the stool and diarrhea. Such unpleasant symptoms are stopped by reducing the single dose of the drug.
It should also be noted that clinical cases are known when, while taking a magnesium preparation, patients developed skin allergies in the form of a characteristic exanthema, urticaria, papular and hyperemic rashes, and itching. The appearance of such signs requires an immediate appeal to the attending physician to adjust the dose taken.
Interaction
Is it possible to combine the drug "Magnerot" with other means? Instructions for use (the price of this medicine is not very high) states that this medication should not be combined with iron s alts, tetracyclines and sodium fluoride, since the intestinal reabsorption of the latter is significantly reduced.
With the parallel use of magnesium with antipsychotics, sedatives or tranquilizers, their pharmacological action is potentiated.
When "Magnerot" is combined with antihypertensive and antiarrhythmic drugs, the severity of their therapeutic effect is enhanced (bradycardiac or hypotensive crises are possible).
Similar drugs and drug price
You can replace the medication in question with such means as Panangin and Asparkam. Also in pharmacy chains there are many other vitamin complexes containing magnesium.
As for the price, you can buy this drug for 160-180 rubles.
Reviews about the tool
Consumer reviews of this drug indicate its positive effect on the human body. Patients claim that after taking Magnerot, their general condition has become noticeably better.
Satisfied with this tool and many experts. They report that its use greatly reduces the risk of CHD. This fact is confirmed by numerous statistics.
Also about the drug "Magnesium Orotate" leave their reviews and pregnant women. They claim that taking this remedy eliminated their night cramps, and also reduced the manifestations of irritability and nervousness. However, doctors advise that taking this medication while carrying a fetus should only be under the supervision of a qualified doctor.
