What does a blood test show at the CEC? Let's figure it out.
Circulating immune complexes in the blood plasma indicate the presence of various inflammation processes in the human body. Thanks to this analysis, you can find out about the presence of autoimmune pathologies in the patient and observe their activity. Such a diagnosis is prescribed by a doctor in a situation where it is impossible to diagnose a patient for a number of reasons, but he has reason to suspect the presence of fungal and viral autoimmune diseases. A blood test for the CEC is done among both adults and children. Such a study can be done as a separate procedure, and simultaneously with other blood tests.
Description of blood test
CEC are components, the beginning of which is produced in the human body. They are produced in the blood in response topenetration of foreign bodies. Such complexes include antibodies, antigens and other elements. If a person has a corresponding reaction and a violation of DNA production, this indicates a malfunction of the immune system in the patient's body. The main purpose of such components is to detect and remove pathogenic allergens and bodies from the body as quickly as possible. After the CEC has performed its function, they are most often destroyed under the influence of phagocytes.
Where are the CECs formed?
Circulating immune complexes can form either directly in the blood or in the liver. In case of their uselessness, they are simply excreted from the human body. If the patient is very ill, suffering from an infectious disease, the content of the components increases to a large extent. In this case, their deposition on the liver begins and, as a result, a dense film is formed, which provokes the onset of the inflammation process. If such a lesion was not diagnosed at an early stage, it can cause the pathology to spread to other organs inside the abdominal cavity. These changes often lead to cancer. The normal degree of CEC in blood plasma ranges from 30 to 90 IU per milliliter.
Preparing for the study
Before a blood test for the CEC, it is strongly advised to exclude smoking and increased physical activity. Biomaterial is recommended to be taken before 10 am, on an empty stomach. It is best that at least eight hours elapse between the last meal and the analysis. While drinking waterallowed.
Transcription of analysis
For the CEC in a blood test, the norm is 0, 055-011 conventional units. Patients often ask the question: "What does an increase in circulating immune complexes mean?". In this case, the extent to which this indicator is increased is of great importance.
The interpretation of a blood test at the CEC should be carried out by a highly qualified specialist.
With a moderate deviation, we can talk about the presence of inflammatory pathologies (sometimes this is even a variant of the norm). With a significant increase, most often we are talking about autoimmune diseases.
Why and when is the study done?
CEC blood test required for symptoms: allergies; complications after the operation; oncopathologies; various kinds of immunodeficiencies; autoimmune pathologies; recurrent or prolonged infections.
Gynecologists in many situations, thanks to this analysis, can determine the characteristics of the course of the disease, establish its origin and understand what are the causes of miscarriage.
We continue to consider deviations from the norm and the interpretation of the results of a blood test at the CEC.
Increase of the indicator and its value
Besides the fact that the body creates circulating immune complexes, it also destroys them. Phagocytes act on bodies that have already fulfilled their function of protection, and eventually destroy them. However, with an autoimmune disease in a patient, this means that the body either produces too many antibodies at a time, or they are not destroyed.after completing his task.
When developing a set of CECs, they lose their inherent properties. In the human body, as a result, there are a large number of elements that are not able to protect it and provoke inflammation processes. Excess or unused circulating immune complexes are deposited on human organs. The kidneys, which are covered with a cellular layer of elements, are especially affected, which makes their functioning difficult. An inflammatory process begins that can cause disease progression, tissue destruction, or a partial degree of organ atrophy.
The formation of antibodies is a necessary process that should be in the body. With an excessive number of complexes and malfunctions of their functions, allergens and viruses can penetrate into the body, which will have nothing to oppose. The human body in such a period is especially prone to numerous diseases. Even an ordinary SARS can cause significant disorders and develop into another pathology.
If the complexes in the blood of a person are in an increased amount, then the formation of both inflammatory processes and tumors is observed in the body. Such neoplasms and diseases can cause the development of diseases and serious damage to all internal organs and the immune system. To conduct the study, the patient needs to take a blood test, which will then be connected to the C1q elements. The result will be determined by the degree of ability of plasma cells to interact with these components. When the CEC in the blood testelevated, how to treat pathologies, it is important to find out in advance.
Reducing element content
If the amount of CEC decreases, this entails various deviations and tissue destruction. Insufficient production of elements causes diseases of the immune system, since the body is no longer able to defend itself against pathological factors. With an insufficient content of complexes, this leads to their accumulation on individual organs. The main functions of substances are lost, they grow on the tissues of the body and destroy it.
This happens due to cellular decay and a decrease in the density of the walls of blood vessels. As a result, the degree of CEC in tissues increases, and phagocytes are no longer able to split them.
CIC can be present not only independently in the blood plasma, but also bind to erythrocytes. These links in deficiency or excess do not have a destructive effect and do not significantly harm the body, therefore, in the analysis, attention is paid only to the presence of elements directly in the composition of human blood.
You can check the level of components by reacting to substances such as C1g and C3d. With a significant decrease in indicators, we can talk about damage to the gene responsible for the transformation of protein elements in the body. A lower degree indicates the presence of vasculitis, an autoimmune lesion, or an allergic disease. Such an indicator often indicates the presence of endocarditis, infectious arthritis, HIV or hepatitis.
CEC in the blood test for opisthorchiasis
Infection with helminths manifests itself in the form of a large number of symptoms that are characteristic of other diseases and have nothing to do with invasion. Therefore, diagnosing helminthiases is a difficult task.
If we are talking about a dangerous infection - opisthorchiasis, the importance of its correct and timely determination increases many times over.
Opisthorchiasis is a helminthiasis caused by a trematode in the family Opisthorchidae.
A person becomes infected by eating fish from the carp family, affected by opisthorchis larvae. The disease is associated with the functioning of parasites in the ducts of the pancreas and liver. The main pathological process is chronic cholangitis and inflammation of the pancreatic ducts.
Detect antigens allow circulating immunocomplexes, if the invasion is chronic, long-term. However, to conduct a blood test at the CEC, expensive, complex, special equipment is needed, which is not available in every clinic. Among other things, a set of special reagents is required to determine the CEC.
Plasma circulating immune complexes indicate various kinds of inflammatory processes occurring in the body.
Conclusion
Circulating immune complexes are an auxiliary diagnostic method and reflect the state of the body as a whole (the extent to which it has suffered frominfections). The CEC indicators also speak about his condition, and if they exceed the set value (1:100), we can talk about the presence of an infectious or inflammatory process in the body, that is, the presence of parasites in it.
We looked at how a blood test is done at the CEC.
