In case of gastrointestinal motility disorders, doctors prescribe drugs based on trimebutine maleate. These drugs have few contraindications and rarely cause unpleasant side effects. Such medicines eliminate cramps and pain in the abdomen in just half an hour. At the same time, they normalize muscle tone not only in the intestines, but also in the stomach and esophagus.
Composition and action of drugs
The active ingredient of the drug is trimebutine maleate. It affects the formation of amino acid residues and regulates gastrointestinal motility. With spastic phenomena in the intestines, stomach or esophagus, trimebutine relaxes the muscles of the internal organs. If there is a decrease in the tone of the digestive organs, then the drug stimulates peristalsis and promotes emptying.
The therapeutic effect comes pretty quickly. Within 30 minutes after taking the medicine, abdominal pain disappears and spasms disappear. At the same time, trimebutine affects only the smooth muscles of the digestive tract, but does not affectcentral nervous system.
The medicine is produced in different forms:
- Pills. Each contains 100 mg of the active ingredient.
- Powder in vials. This form is intended for the preparation of a suspension. It is taken orally or rectally (through an enema). 5 ml of the suspension contains 24 mg of the medicinal substance, and one vial of the powder contains 1.2 g.
- Solution in ampoules. Each ampoule contains 50 mg of trimebutine. This form of medicine is intended for intramuscular and intravenous injections.
Indications and contraindications
Instructions for the use of trimebutine maleate recommends prescribing this remedy for the following diseases and conditions:
- dyspeptic symptoms associated with impaired peristalsis;
- pathologies of the stomach and duodenum;
- abdominal pain due to cramps;
- flatulence;
- impaired bowel function due to dystrophic changes;
- reflux of stomach contents into the esophagus (reflux).
Also, this remedy is used before X-ray and endoscopic examination of the digestive tract.
This medicine is relatively harmless. It has few contraindications. The drug should not be used by people who are allergic to trimebutine maleate. For children, this remedy can be taken over the age of 3.
During pregnancy, the drug can be used only in the second and third trimesters. On theearly terms this medicine is contraindicated. During lactation, you need to stop taking the medication.
Unwanted effects
Usually taking the drug is not accompanied by any discomfort. However, the instruction of trimebutine maleate warns of the possible development of allergies during the course of treatment. Such manifestations indicate an increased sensitivity of the patient to trimebutine. In this case, the drug should be discontinued.
When the drug was injected into a vein, some patients experienced fainting. In case of loss of consciousness, the patient must be given first aid. In such cases, the patient is transferred to other forms of the drug (in the form of tablets or suspension).
How to use
The dosage of the medicine is selected by the doctor individually for each patient. On average, the following doses are prescribed:
- oral: up to 300 mg daily;
- rectally: 0.1-0.2 g of the active ingredient per day;
- IV or IM: 1 ampoule (50mg) daily;
- children (in tablet form): 25-50 mg three times a day.
Storage, price and analogues
Powder, tablets and ampoules are stored at a temperature not exceeding +25 degrees. They can be used for 1.5 years. The prepared suspension can be stored for no more than 1 month.
You do not need a prescription to purchase this drug. However, this does not mean that the medicine for spasms can be taken on its own. Only a doctor can decide whether this medication is appropriate.
WhatAs for the price of the drug, it depends on the manufacturer. After all, trimebutine maleate is the name of the medicinal substance. And medicines containing this component can be produced under different trade names:
- "Neobutin";
- "Neobutin retard";
- "Trimedat".
All these drugs have the same composition. They are structural analogues of trimebutine maleate.
The price of the drug "Neobutin" is 360-400 rubles. Its prolonged form "Neobutin retard" is somewhat more expensive (from 400 to 450 rubles).
The cost of the drug "Trimedat" varies from 260 to 530 rubles, depending on the form of release.
Reviews
You can find a lot of positive reviews about preparations based on trimebutine. Patients consider these drugs effective antispasmodics. After the course of treatment, the patients disappeared pain in the abdomen, flatulence, feeling of heaviness in the stomach. The drug normalizes the stool and helps to get rid of constipation and diarrhea for a long time.
Some patients experience slight dizziness after taking antispasmodics. However, when using drugs with trimebutine, there were no unpleasant sensations. The cost of these drugs is quite high, however, many patients prefer to take these antispasmodics.
Patients note that counterfeit antispasmodics with trimebutine are often found. They do not have any healing effect. That's whythe medicine must be purchased only in reliable and trusted pharmacy chains.
