The drug "Neurodiclovit" instructions for use calls it an effective non-steroidal agent that has anti-inflammatory, antiaggregatory, analgesic and antipyretic effects. The above medicine perfectly eliminates the symptoms of neuralgia, degenerative diseases of the joints and relieves the pain syndrome that occurs with various types of inflammation that are of a non-rheumatic nature. Read on for details about Neurodiclovit. Its price is also listed below.
Neurodiclovit tablets: a brief description
The above drug is available in the form of gelatin capsules, which have a brown cap and a pinkish-yellow body. Inside these pillscontains diclofenac sodium in the form of a white granulate and vitamins in the form of a pink powder.
Drug instruction for use advises to keep away from children, in a well darkened and dry place. The temperature of the room where the remedy is located should not exceed 25 degrees Celsius.
If all storage standards are observed, the shelf life of the drug is 2 years.
It should also be noted that this tool affects the ability to control mechanisms and drive vehicles. Therefore, while taking the above drug, you should refrain from such activities.
This medicine is available from a pharmacy with a special prescription.
Composition of the drug "Neurodiclovit"
Healing product contains the following ingredients:
- diclofenac sodium;
- cyanocobalamin;
- thiamine hydrochloride;
- pyridoxine hydrochloride;
- other substances.
Also in the drug "Neurodiclovit" (instructions for use confirms this), includes the following excipients:
- talc;
- ethyl acrylate copolymer;
- triethyl acetate;
- methacrylic acid;
- Povidone K25.
One package contains 10 capsules.
The instruction calls Neurodiclovit an oral remedy. Diclofenac sodium is well absorbed within two hours. B vitamins are absorbed in the intestines.
About 60% of diclofenac sodium is excreted by the urinary system, 30% - by the intestines. The instruction indicates that the age of the patientdoes not affect the pharmacokinetics of diclofenac sodium at all. It should be noted that this substance passes into breast milk.
Pharmacological action
The drug "Neurodiclovit" instructions for use describes how a remedy that combines B vitamins and diclofenac sodium. The latter is a nonsteroidal anti-inflammatory agent. Together with sodium neurotropic vitamins, diclofenac quite effectively relieves pain and significantly reduces the level of inflammation in pathologies of the musculoskeletal system and neuralgia.
The instructions for use accompanying the Neurodiclovit preparation contain information that it is a narcotic analgesic. The main substance that is part of its composition is diclofenac sodium. It inhibits lipoxygenase and cyclooxygenase, promotes the process of reducing the synthesis of inflammatory mediators, mainly prostaglandins. Diclofenac is distinguished by its ability to reduce the intensity of inflammation, relieve swelling, and also pain in the joints.
B vitamins act as coenzymes and produce a neurotropic effect on the patient's body. Thiamine plays a fairly significant role in fat, protein and carbohydrate metabolism. In addition, the above substance contributes to the conduction of nerve excitation in synapses.
In order for the peripheral and central nervous systems to function normally, the patient's body needs vitamin B6. This substanceis an active participant in the biosynthesis of many neurotransmitters, such as serotonin, adrenaline, dopamine, norepinephrine, histamine, etc.
Cyanocobalamin has a significant impact on the normal implementation of hematopoietic processes. The above vitamin contributes to the maturation of red blood cells. This substance is one of the active participants in biochemical reactions. This is the synthesis of nucleic acids, the exchange of amino acids, lipids and carbohydrates, the transfer of methyl groups. The coenzymes of cyanocobalamin are adenosylcobalamin and methylcobalamin. They promote cell replication and growth.
Instructions for use certifies that B vitamins potentiate the analgesic effect of diclofenac sodium.
Neurodiclovit tablets: indications for use, price
The drug is popular among many specialists. So, what are the Neurodiclovit tablets from? The instruction suggests using this drug for the treatment of the following diseases:
- acute gouty arthritis;
- lesion (rheumatic) of soft tissues;
- neuralgia (lumbago, cervical syndrome, sciatica);
- degenerative and inflammatory diseases of the spine and joints (rheumatoid arthritis, osteoarthritis, rheumatoid arthritis, spondylarthrosis, chronic polyarthritis, ankylosing spondylitis);
- pain syndrome when observing signs of inflammation that are of a non-rheumatic nature (after dental and surgical interventions, with inflammatory processes in the ENT area(tonsillitis, pharyngitis, otitis), with gynecological diseases (adnexitis, primary algomenorrhea), as well as after injuries).
The price of the drug is an average of 220 Russian rubles for 30 capsules.
Contraindications
The Neurodiclovit drug, the indications for which are outlined above, is not allowed to be taken by all patients. It depends on the individual characteristics of the patient's body. So, there is a group of patients for whom it is completely contraindicated to use the drug "Neurodiclovit" in the therapeutic course. The instruction indicates a number of diseases in which it is undesirable to use this remedy:
- intracranial hemorrhage;
- erosive and ulcerative formations in the digestive organs;
- bronchial asthma, which is also accompanied by symptoms of polyposis of the nasal mucosa;
- impaired hemostasis;
- hematopoietic disorder.
The instruction recommends using Neurodiclovit with caution for signs of the following diseases:
- bronchial asthma;
- anemia;
- arterial hypertension;
- heart failure (congestive);
- edematous syndrome;
- alcoholism;
- liver failure;
- diabetes diabetes;
- kidney failure;
- inducible porphyria;
- diverticulitis;
- inflammatory diseases of the digestive tract;
- systemic connective tissue diseases.
In addition, small patients, that is, children, are prohibited from taking pills"Neurodiclovit" instruction. The above remedy is also contraindicated for mothers who are breastfeeding and women in position. Experts note that this drug can contribute to the occurrence of malformations in the embryo or fetus. Also with mother's milk, sodium diclofenac gets to the baby, which can adversely affect his he alth.
Also, older people are advised to be careful with the drug "Neurodiclovit" instructions for use. The tablets should also not be given to patients who are undergoing rehabilitation after major surgery.
Side effects
In some cases, side effects may occur when using the drug "Neurodiclovit". Indications for use and recommended dosages sometimes do not bring the desired result. On the contrary, some patients after taking the above drug complain of the occurrence of discomfort and conditions:
- from the side of the nervous system: dizziness, drowsiness, sleep disturbance, headache, irritability, depression, general weakness, convulsions, disorientation, feeling of fear, aseptic meningitis, nightmares;
- from the gastrointestinal tract: diarrhea or constipation, abdominal pain, nausea, peptic ulcer with various symptoms of complications, flatulence, dry mucous membranes, feeling of bloating, aphthous stomatitis, gastrointestinal bleeding, liver necrosis, vomiting, hepatorenal syndrome, cirrhosis of the liver, change in appetite,cholecystopancreatitis, colitis, pancreatitis;
- from the senses: blurred vision, scotoma, taste disturbance, diplopia, tinnitus;
- from the genitourinary system: fluid retention, oliguria, proteinuria, hematuria, nephrotic syndrome, papillary necrosis, renal failure (acute), azotemia;
- from the respiratory system: cough, pneumonitis, bronchospasm, laryngeal edema;
- from the side of the heart: increased blood pressure, chest pain, heart failure (congestive), myocardial infarction.
Also, there may be:
- anaphylactic shock, swelling of the tongue and lips, anaphylactoid reactions, allergic vasculitis;
- skin rash or itching, erythema multiforme exudative urticaria, toxic dermatitis, eczema, increased photosensitivity, toxic epidermal necrolysis, punctate hemorrhages, alopecia.
It is very important to take into account the indications for use and not only when using Neurodiclovit. In no case should you ignore the above side effects. If these symptoms are observed, the instruction recommends that the patient stop using the Neurodiclovit drug. Reviews of specialists contain advice that such a patient must seek qualified medical help.
How to take the above drug? Overdose
Capsules should be washed down with a sufficient amount of liquid. The drug should be taken at the time of takingfood.
For adult patients, specialists usually prescribe 1 capsule every 8 hours at the initial stage of treatment. The patient will consume approximately 100 mg of diclofenac sodium. Then the dosage changes slightly: the drug should be taken 1-2 times a day as maintenance therapy.
For patients under 14 years of age, the maximum dosage of the above medicine should not exceed 2 capsules per day.
Older people should not use this product for medicinal purposes, or treat it with great caution.
The duration of the course of therapy depends on the severity and nature of the disease.
Experts warn that it is very important to comply with the specified norm and in no case exceed it without the doctor's permission. Otherwise, symptoms of drug overdose may occur. These are headache, convulsions, nausea, impaired functioning of the kidneys and liver, shortness of breath, abdominal pain, clouding of consciousness. In this case, experts advise to immediately take the following actions:
- well rinse the stomach;
- use activated charcoal tablets;
- will seek medical help (forced diuresis and symptomatic therapy are carried out).
Interaction of this medicine with other medicines
When using the above drug, it should be remembered that it increases the plasma concentration of methotrexate, digoxin, cyclosporine and lithium. In addition, Neurodiclovit has the following interactions with other drugs:
- reduces tominimize the effect of hypoglycemic drugs;
- reduces the effects of sleeping pills and antihypertensive drugs;
- enhances the effect of therapeutic agents that cause photosensitivity;
- helps increase the likelihood of side effects of other corticosteroids and NSAIDs;
- increases cyclosporine nephrotoxicity and methotrexate toxicity;
- lowers the antiparkinsonian high efficacy of levodopa.
You should also take into account other nuances in the interaction of the drug "Neurodiclovit" with other therapeutic agents:
- acetylsalicylic acid significantly lowers the concentration of diclofenac in the blood;
- ethanol prevents the absorption of thiamine into the blood;
- drugs that block tubular secretion increase the toxicity of diclofenac;
- biguanides and colchicine minimize the absorption of cyanocobalamin.
If Neurodiclovit is used simultaneously in combination with St. John's wort, bleeding in the gastrointestinal tract may occur.
It should also be remembered that the substance paracetamol significantly increases the risk of nephrotoxic effects of diclofenac sodium.
Preparations that contain valproic acid, cefotetan, plicamycin, cefamandol, in combination with the above therapeutic agent can contribute to the development of hypoprothrombinemia.
Neurodiclovit drug: analogues
The price of the above remedy is acceptable, according to patient reviews. But sometimes there are situations when you just need to knowwhat can replace the above remedy. For example, the drug "Neurodiclovit" may simply end in a pharmacy. Its analogues are as follows:
- "Blockium B12";
- "Cinepar";
- "Bal Run";
- "Diclofenac";
- "Flamides";
- "Dolex";
- "Olfen-75";
- "Fanigan";
- "Diclocaine";
- "Diclofenac With Paracetamol";
- "Maxigesic".
It should be noted that the group of medicines for pain in the back, muscles and joints also includes the drug Neurodiclovit. Its analogues here are "Mirloks", "Ben-Gay", "Melbek".
In addition, the above medicine also belongs to this group of anti-inflammatory nonsteroidal drugs. Substitutes for the drug "Neurodiclovit" here are such means as "Analgin-Ultra", "Bi-xicam", "Xefocam".
The group of drugs for the treatment of diseases of the joints and spine also includes the drug Neurodiclovit.
Analogues, the price of which is sometimes much higher, can not be used in all cases instead of Neurodiclovit. It should be noted that a drug substitute can only be used after consultation with an experienced specialist. Doing it yourself is by no means recommended.
Doctors' opinion about the drug
Feedback from experts is predominantly positive ifconsider the evaluation of the therapeutic effect of the drug "Neurodiclovit". Reviews of doctors contain information that its effectiveness is clearly visible after the first course of therapy. It is only important to strictly observe the dosage prescribed by the doctor. In addition, doctors say that side effects are extremely rare.
Reviews of specialists focus on the fact that during the course of therapy with the above drug it is very important to systematically monitor the state of peripheral blood, kidneys and liver function, as well as conduct stool studies for the presence of blood in it.
Patient Feedback
Many patients note the high therapeutic efficacy of the drug "Neurodiclovit". Reviews of patients suffering from intercostal neuralgia suggest that this drug easily relieves the symptoms of an exacerbation of the disease. It becomes much easier to move, the remedy works very quickly.
In addition, many patients claim that the drug "Neurodiclovit", the price of which, in their opinion, really justifies itself, also relieves pain in the head, spine, hypochondrium (with biliary colic) and even in the teeth.
Some patients point out that the big disadvantage of the above remedy is the long course of therapy. In some cases, after such treatment, patients begin to have stomach problems.
The Neurodiclovit drug, the price of which is quite acceptable for most patients, is indeed a fairly effective drug. It must be taken according to the doctor's prescription, not inunder no circumstances exceed the dosage. If you experience any side effects, seek medical attention immediately.
