Diseases of the nasopharynx occur in everyone, there is no such person who would never experience problems with nasal congestion and swelling, runny nose. Thanks to the development of pharmaceuticals, new products are being launched on the market that can comprehensively act on the causative agent of the infection that causes the disease. One of these refers to the latest generation of antibiotics - "Polydex" with phenylephrine. What is it and how to use it? You can learn about this by reading this article.
Issue form
In the pharmacy network, Polydex nasal spray with phenylephrine is sold only in this form, drops or solutions are not provided. For ease of use, the opaque bottle is equipped with a convenient spray dispenser. The solution itself is clear.
Drug composition
When prescribing any drug, its composition is taken into account, it determines the effectiveness and duration of treatment. Naturally, when it comes to antibiotics, you want to feelimprovement after a short period of use and so that the benefit is greater than the harm. Studying the instructions for Polydex with phenylephrine, you pay attention to the fact that the drug has several active ingredients. This suggests that it is more versatile in terms of fighting viruses and pathogenic microbes.
According to the instructions for "Polydex" with phenylephrine, the composition includes substances such as:
- Polymyxin and neomycin sulfate (10,000 units and 10mg);
- Metasulphobenzoate (250mcg);
- Phenylephrine hydrochloride (2.5mg);
- Dexamethasone (0.25 mg).
How the main components work
As indicated in the instructions for use of the spray "Polydex" with phenylephrine, it has a complex effect. Remove swelling of the nose allows one of the active ingredients, which is indicated in the name of the drug - phenylephrine. It also helps to reduce the release of pus from the mucosa of the paranasal sinuses. Neomycin acts as an antibiotic, actively fighting gram-positive bacteria, and polymyxin - with gram-negative.
The hormonal component of Polydex with phenylephrine is dexamethasone, which belongs to the group of glucocorticosteroids. Thanks to this substance, there is a rapid regeneration of the damaged mucosa, blood vessels, getting rid of the allergic reaction and the inflammatory process.
Pharmacodynamics and pharmacokinetics
The main cause of diseases of the paranasal sinuses and nasal cavity - gram-positive and gram-negative bacteria. Thanks tothe action of two antibiotics, polymyxin B and neomycin sulfate, it is possible to achieve a stable positive therapeutic effect in the fight against staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, Pfeiffer's bacillus. However, it should be borne in mind that if the cause of the disease of the nasal cavity is anaerobic and aerobic bacteria, diphtheria, the causative agent of tuberculosis, fungi, clostridia, then the drug will be ineffective.
The hormonal component dexamethasone, sodium metasulfobenzoate and phenylephrine in combination work with the inflammatory process, and also act as anti-allergic components. Both ingredients fight against the focus of the spread of harmful microbes, infections.
Indications for use
Due to the fact that the Polydex spray with phenylephrine contains a hormonal component, it is not recommended to use it on your own, without a doctor's prescription. Even if there are all the signs on the face that can be used to judge the possibility of its use, it is important to understand that the causative agent of the infection can be a virus that cannot be defeated by this remedy.
You can study the instructions for the use of "Polydex" with phenylephrine and understand how it corresponds to the available indications in a particular case. These include chronic and acute rhinitis, sinusitis, nasopharyngitis.
In addition to the therapeutic effect, the drug is prescribed for prevention after surgery in the sinuses and nasal cavity. The rationale for the appointment in this case is an obstacle to the development of inflammation and ingestioninfections.
To whom the drug is contraindicated
Studying the wide scope of "Polydex" with phenylephrine made it possible to understand which organs and systems of the body the components act on. Therefore, contraindications are not limited to one or two points. If a person knows that among the obstacles to use there is a disease that he has been diagnosed with, then, of course, you should refrain from taking the drug.
Following the manufacturer's recommendation, contraindications for prescribing Polydex with phenylephrine include:
- Closed glaucoma (suspicion of its formation).
- Taking antidepressants due to the risk of developing a hypertensive crisis.
- The first symptoms of a runny nose.
- Albuminuria, which often occurs with kidney disease.
- Angina pectoris, increased levels of hormones secreted by the thyroid gland, high blood pressure.
The use of this drug is also contraindicated in persons who are hypersensitive to its active ingredients.
Method of application and dosage
As a rule, the doctor describes the scheme for using the Polydex spray with phenylephrine. The instructions also include a description of the treatment:
- Children aged 2, 5, and teenagers under 18 - no more than three times a day.
- Adults - 3 to 5 times a day.
The total duration of treatment is determined by the severity of the disease, regulated by the attending physician, on averageis 5-10 days. One of the features of the application is the need to warm the solution to room temperature before use. To do this, you can hold the bottle in your palms for a while.
Special Instructions
Before the attending physician prescribes "Polydex" with phenylephrine, he must be informed of the existing chronic diseases. This applies to patients suffering from renal insufficiency. A special category includes those who have heart disease, with caution prescribe the drug for hyperthyroidism, arterial hypertension, coronary heart disease.
Because it is in the form of a spray, it is important to avoid contact with the eyes. If this happens, then you must immediately rinse them with warm water. Seek medical advice if severe irritation occurs.
The drug is used strictly according to the instructions for medicinal purposes, it is impossible to wash the sinuses. The components of the drug do not adversely affect driving.
Conditions for the use of "Polydex" by a special category of patients
It should be borne in mind that since the composition contains a hormonal component, it is not recommended to use the drug for pregnant women and during breastfeeding without a reasonable doctor's recommendation. This is due to the high toxicity of the components of the drug. It can have a negative effect on the fetus and lead to congenital malformations of the hearing organs. When a woman is breastfeeding,active substances can enter the body of the baby with milk. The child may become lethargic, drowsy, in some cases tachycardia is noted. The only condition for the use of the drug during this period is the transfer of the child to artificial feeding.
If we talk about children, then the minimum age is 2.5 years. After examination by a doctor, the drug is prescribed for the treatment of adenoiditis, inflammatory and purulent diseases of the nasopharynx. In order to determine the dosage and duration of treatment, a complex of studies and the lack of positive dynamics of previous treatment regimens are needed.
Interaction with other drugs
It is important to know that phenylephrine can have a negative effect (that is, reduce the effect) of taking antihypertensive drugs and diuretics. With the simultaneous administration of drugs, which include guanethidine, the patient may experience dilated pupils. Taking Polydex and cyclopropane in combination leads to ventricular fibrillation, so you should inform your doctor about taking this drug.
If antibiotics such as Amikacin, Gentamicin, Monomycin, Streptomycin, Netilmicin have already been prescribed, it is necessary to refrain from the drug until the end of their course. Simultaneous use can cause problems with the vestibular apparatus, hearing loss. Since the composition contains dexamethasone, it is not recommended to use Erythromycin, Bepridil, Terfenadin, Astemizol and other similar drugs as a treatment with it, as they adversely affectwork of the heart muscle.
If a patient has been taking drugs with acetylsalicylic acid for a long time, antiarrhythmic drugs (Disopyramide, Quinidine, Sotalol), then Polydex should be used with caution as a treatment. During polio vaccination in children, as well as BCG vaccination, it is necessary to refrain from using a spray or inject only after recovery. This is associated with a high risk of disability and death.
Side effects
Most often, when taking medications, an allergic reaction occurs. This tool is no exception. Perhaps the appearance of a burning sensation and itching, urticaria during therapy. As for the nasal cavity itself, in some cases there was a burning sensation and dryness in the nose after injection of the drug. If these sensations cause severe discomfort and become regular, you should consult a doctor to adjust the dosage or treatment regimen.
Analogues
At the moment there is no such drug that would have an identical composition and could become an analogue of "Polydex" with phenylephrine. Despite this, there are many other drugs that will be cheaper and can cope with the same symptoms. However, it should be borne in mind that the specifics of the appointment of this particular dosage form, due to the complexity of the course of the existing disease, it is not suitable for permanent use.
One of the similar products on the pharmaceutical market is Isofra. It has a positive effect in the treatment of rhinitis, rhinopharyngitis, sinusitis, as well as after a surgical intervention in order to prevent the occurrence of an inflammatory process. Can be given to children from the first year of life.
"Sofradex" - a combined drug, contains dexamethasone, which is also one of the active ingredients of "Polydex". If you look at the indications for which it is prescribed, then most often it is a problem with adenoids. In other cases, it is more used to treat diseases of the ears and eyes. It is recommended to use this analogue only after consultation with your doctor.
"Avamys" has an active ingredient different from "Polydex" - fluticasone furoate. Age restrictions for use in childhood are the same. Suitable for the treatment of rhinitis, relieves swelling in adenoiditis. Also, for the treatment of these symptoms, Flikonase is suitable, with a similar active ingredient. These two drugs, most likely, are even more suitable as an analogue to each other than to the Polydex drug.
Reviews
Those who have repeatedly encountered diseases of the nasal sinuses know about the positive effect of the drug "Polydex" with phenylephrine. Reviews of its properties justify its use at a time when it is not about simple nasal congestion or a cold. Since the components of the drug are quite serious, you should get the approval of a doctor before starting treatment.
Doctors, in turn, resort to this medication only after establishinga definitive diagnosis because it has clear indications for use as a primary treatment. Moreover, there is a separate category of patients for whom it is categorically contraindicated. We are talking about athletes who, using Polydex, can get positive results of a doping test.
If we talk about the speed of action, then the reviews of patients who are faced with the need to use it, speak of a quick result. The swelling of the nose is removed after the first days of treatment, and after a week the disease completely recedes.
