According to the instructions for use, "Essentiale" in ampoules is a drug from the group of hepatoprotectors, which contains natural phospholipids, constantly needed by the body from the outside, since such compounds cannot be synthesized in its cells. These elements are called essential. They can be compared to essential amino acids that are constantly required by the human body and must come from food.
Therapeutic effects of Essentiale
The therapeutic effect of all varieties of "Essentiale" is determined by its constituent phospholipids. Vitamins in the composition of the drug can not only enhance the effects of these important components, but also make up for their deficiency in organs and tissues. Thus, vitaminsplay a significant role in the main therapeutic effect of the drug in question. In order for readers to have an idea of \u200b\u200bhow this drug should look like, we provide a photo of "Essentiale" in ampoules. We will consider the instructions for use in this article in full detail.
To begin with, we note that phospholipids, which are part of "Essentiale", normally act as substances that make up the structure of the cell membrane. Phospholipids themselves are complex organic compounds that have a short "head" of phosphatidylcholine and long tails of unsaturated fatty acids such as linolenic and oleic. It is worth mentioning that in their structure, phospholipids resemble spermatozoa, only in contrast to them they have two tails, which consist of fatty acids. Instructions for use for "Essentiale" in ampoules tells in some detail about the principle of their action for liver he alth.
Thus, phospholipids line up in a row with their "tails" in the direction of one side, and "heads" in the direction of the other. After that, two similar rows are interconnected by “tails” in such a way that their “heads” turn out to be turned inside the cell, that is, into the cytoplasm, and the second part is turned into the region of the intercellular space. This is indicated by the "Essentiale" in ampoules instructions for use. It is important to note that cats can also be given this drug.
Thus, phospholipids are required for the construction of cell membranes in the human body. In that case,if they are not enough, the membranes will be fragile, as a result of which substances that they do not need can enter the cells, which will provoke their death. Membrane damage results in premature cell death. This confirms the instructions for use for "Essentiale" in ampoules. The description of the action of the drug can be continued.
Due to the fact that phospholipids after the process of absorption in the intestine are primarily in the liver, it is here that they are integrated into the membranes, improving their properties and normalizing the structure. The hepatoprotective effect of the drug "Essentiale Forte" in ampoules consists in improving the quality of the structure of cells, as well as in increasing their endurance. Instructions for use also describe these features of the drug.
Due to a positive effect on the structure of cells, the drug reduces the number of dead liver elements. This contributes to the normalization of the functioning of the body, creating all the prerequisites for its effective work in the future. In other words, "Essentiale" seems to prolong the vital activity of cells, providing an improvement in the functioning of the liver for a very long period, until the supply of phospholipids runs out, and the necessary elements begin to die again in large numbers.
Against the background of the use of the drug in question, normalization of laboratory parameters of liver functions due to hepatitis, fatty degeneration, cirrhosis is noted, and, in addition, cell resistance to toxicimpact. In addition to the normalization of indicators, under the influence of the drug "Essentiale" in ampoules (according to the instructions for use), the severity of necrosis, as well as inflammation occurring in the liver tissues, decreases.
Thus, the effects that the drug has on the liver are expressed in the following results:
- The integrity of the liver cell membrane is being restored.
- The normal integrity of the liver cell membrane is preserved, as well as its structure.
- The work of membrane enzymes is activated, which ensure the transport of various substances both into the interior of the cell and out.
- Improves lipid and protein metabolism.
- Glycogen stored in the liver increases.
- The detoxification function of the liver improves, that is, there is an increase in the ability of the liver to neutralize all kinds of toxic substances, in particular medicines. This is confirmed by the drug "Essentiale" in ampoules instructions for use and reviews.
- Cholesterol and other fats that can cause atherosclerosis are converted into less dangerous forms that are easily eliminated by energy-producing cells.
- Reduces the liver's need for excess energy.
- The fatty infiltration of hepatocytes is reduced or completely eliminated.
- Reduces the risk of sclerosis, fibrosis and cirrhosis of the liver.
- The chemical and physical properties of bile are normalized, in the process of which its lithogenicity decreases, that is, the ability of bile to form stones inbubble.
In addition to the effects of a positive effect on the liver, all varieties of the drug "Essentiale Forte" in ampoules (instructions for use confirm this) can have the following effects on other organs and systems of the body:
- The size and the total number of atherosclerotic plaques are reduced due to the normalization of the volume of lipoproteins of both high and low density in the blood thanks to "Essentiale" in ampoules. The instructions for use also mention this important property of the drug.
- The fluidity of blood is normalized, which reduces its viscosity against this background.
- Cholesterol is removed from atherosclerotic plaques.
- Reduces clinical signs of diabetes.
The good tolerance of Essentiale makes it possible to recommend it for use not only to improve the quality of functions along with the state of the liver, but also as a general tonic, which significantly increases the body's resistance to certain diseases.
How to use the drug correctly
As the instructions for use indicate, "Essentiale" in ampoules is a solution that is used for intravenous administration and contains the same amount of phospholipids - two hundred and fifty milligrams in each ampoule. The solution for injection is administered only intravenously. In no case should it be administered intramuscularly or subcutaneously, since in this case there is a high probability of occurrenceirritation.
An adult can enter two ampoules at once. Against the background of mild or moderate severity of various diseases, due to which "Essentiale" was prescribed, the solution should be administered one or two ampoules per day. If the person's condition is severe, the dosage should be doubled. The maximum possible single dose for adults is two ampoules, and the daily dose is four. This confirms the instructions for use for Essentiale Forte N ampoules.
Children aged three to six years, the drug is administered two milligrams of a solution 1 time per day, and children aged seven to twelve years can use twice the daily dose. If the daily dosage includes no more than two ampoules, then they are administered at one time. When the daily rate of "Essentiale" is four ampoules, they are taken in two pieces in the morning and evening. It is advisable to administer intravenous solutions of this drug for no more than one month, and to continue the course, you should switch to taking capsules. This is indicated by the "Essentiale N" in ampoules instructions for use.
Immediately before administration, it is important to dilute the solution from the ampoules in a ratio of one to one with the patient's blood or a solution of five percent glucose or dextrose. True, a solution of glucose and dextrose can be used only when it is impossible to dilute "Essentiale" with human blood. Do not dilute this medicinal product with saline solutions, such as, for example, saline or Ringer's liquid. In addition, the solution of the drug should not be mixed with otherdrugs in one syringe.
In the event that "Essentiale" was diluted with a solution of glucose or dextrose, it is necessary to carefully monitor its transparency throughout the entire time of administration. If the turbidity of the substance is noticeable, then it is necessary to stop its administration by removing the needle from the vein, and throw away the remnants of the drug, while the missing amount is injected from a new ampoule.
Solution "Essentiale" is administered by jet method, do it slowly, at a speed not exceeding one milligram per minute. For the introduction, a site with high-quality veins is selected. The elbow area is best suited. True, if it is not possible to inject the solution into the veins of the elbow region, then another area is selected, for example, the back of the feet, or the hand, and so on.
At the background of acute liver diseases, therapy lasts from one to three months, depending on the rate of recovery of a person. In case of chronic liver damage, the course of using "Essentiale N" in ampoules according to the instructions for use is at least six months. If necessary, repeat the treatment.
Special instructions for medicinal product
Since all varieties of "Essentiale" contain phospholipids, which are obtained from natural soybeans, they are theoretically capable of provoking certain allergic reactions. Patients prone to such should be careful when using "Essentiale". At the first manifestations of the development of allergic reactionsstop using the drug immediately and contact your doctor.
The solution contains some ethyl alcohol used in the process of extracting phospholipids from beans. The volume of ethyl alcohol content is insignificant and does not cause any reactions that are characteristic of alcohol. During the entire period of therapy, it is important to refrain from using any substances that adversely affect the liver, such as alcohol, drugs, and so on. This is indicated by the instructions for use for the "Essentiale" in ampoules. Contraindications must be taken into account.
Against the background of chronic hepatitis, the drug can be used only if the person's condition improves. For children, it is forbidden to use ampoule solutions for intravenous administration up to three years. The ban on use at such a young age is associated with the content of benzyl alcohol in the composition of the product, which can provoke the formation of Gaspings syndrome with subsequent death. What else does the instructions for use for "Essentiale N" in ampoules tell us?
Side effects
The drug is generally well tolerated and rarely causes any side effects, however, if any occur, stop using this drug immediately and consult your doctor.
Side effects of ampoule solutions used for intravenous injection include the followingsymptoms:
- Allergic reactions of the body, such as various rashes, itching and exanthema along with urticaria.
- Irritation at the injection site.
- Diarrhea due to the use of large dosages of ampoule solution.
The effect of the drug on the ability to drive a car
Essentiale ampoules do not have any negative effect on the driver's ability to drive all kinds of mechanisms, including a car. For this reason, during the entire period of using this drug, a person can calmly and without fear engage in any activity that requires a high speed of reactions, as well as concentration.
This describes the medicine "Essentiale" in ampoules instructions for use.
Overdose
Over the entire period of observation of the clinical use of the drug, an overdose has never been recorded. True, according to theoretical information, the symptoms of an overdose are an increase in the manifestation of possible side effects.
In order to eliminate the symptoms of an overdose, you should completely stop taking the medicine and carry out symptomatic therapy, which will be aimed at maintaining the normal activity of the vital organs of a person.
Instructions for the use of analogues to "Essentiale" in ampoules does not describe, we will consider them below.
Interaction of "Essentiale" with other drugs
Ampoule solution for intravenous administration is able to interact with anticoagulants, thenthere are substances that reduce blood clotting, while enhancing their effect. For this reason, as part of the simultaneous use of these products, it is desirable to reduce the dosage of anticoagulant.
Analogues
In view of the fact that the main active ingredient of the drug are phospholipids, then the analogues of this drug will be other medicinal products that contain these same substances as their active ingredients. True, some drugs, in addition to phospholipids, also contain vitamins. Thus, medications that contain only phospholipids serve as analogues of "Essentiale N" and "Essentiale forte N". And those of them that include both phospholipids and a vitamin complex in their composition act as analogues of "Essentiale" and "Essentiale Forte". Instructions for use indicate which analogues can be used.
The pharmaceutical market offers a wide range of various analogues of "Essentiale", which include drugs from the category of hepatoprotectors, which contain not phospholipids as active ingredients, but other substances that have the most similar list of effects, as well as therapeutic effects.
Thus, the analogues of "Essentiale forte N" in ampoules (instructions for use are in each package) are the following medicinal products:
- Bonjigar capsules and syrup.
- "Dipana" in the form of tablets.
- Karsil Dragee.
- Laennec injection solution.
- "Hepafit" in the form of herbal collection for the preparation of infusions.
- Solution for injection "Metrop GP".
- Progepar capsules.
- "Rosilymarin" tablets.
- Capsules, rectal suppositories, and Tykveol oil.
- Cholenol capsules.
- Solution and tablets "Elkar".
These are all analogues of "Essentiale" in ampoules. Instructions for use and reviews are of interest to many.
Among analogue drugs, the cheapest ones, the cost of which does not exceed three hundred rubles, include the following products:
- "Livolife forte".
- Antralive.
- Brenciale forte.
- Essliver.
Recognized as the most purchased, as well as cheap analogues, are Liv 52 and Karsil.
According to the instructions for use, "Essentiale Forte N" in ampoules is a medical product from the category of hepatoprotectors, which is designed to maintain he althy functioning of the liver, and in addition, to prevent the occurrence of cirrhosis due to chronic diseases of this organ. "Essentiale" perfectly copes with the tasks assigned to it and provides an improvement in the patient's well-being after regular courses of treatment. True, like other drugs, it does not serve as a universal and ideally suitable for absolutely everyone. That is why the question of which medicines are better than Essentiale, from the point of view of specialists, is not correct.
To answer this question, you should know all the features, as well as the reactions of a person to all kinds of drugs fromcategories of hepatoprotectors. Only then will it be possible to determine the group of drugs that will best suit the patient. Then it is necessary to trace which drug has the maximum possible therapeutic effect, without causing side effects. It is this drug that will serve as the best therapeutic agent for this particular patient.
Thus, it is impossible to answer in general which medicines will be better than Essentiale, meaning all patients who suffer from liver diseases, since the body of each person is individual. In general, "Essentiale" is one of the best hepatoprotectors that are available on the pharmaceutical market.
Treatment of cats and dogs
Instructions for the use of "Essentiale" in ampoules for cats and dogs states that the drug for animals is used intravenously. It cannot be used intramuscularly (local reactogenic reaction is possible). The standard dose is taken on the basis of 0.2-0.5 ml / kg of body weight once a day for five to ten days. Severe hepatopathy involves intravenous use twice a day for a couple of weeks. The drug is diluted with autologous blood or dextrose solution.
Reviews
More than ninety percent of drug reviews on the Internet are positive, which can be attributed to the high degree of effectiveness of "Essentiale" in ampoules. The instructions for use describe the drug well.
In their reviews, peoplethey write that the remedy perfectly supports the normal functioning of the liver, and against the background of regular use it prevents the manifestation of any unpleasant clinical symptoms. In addition, Essentiale, when used for long courses in the case of cirrhosis and hepatitis, is able to stop the progression of diseases, while preventing them from moving into more severe stages, which thereby prolongs a person’s life and maintains its quality.
Some reviews indicate that when using "Essentiale" in ampoules intramuscularly (instructions for use confirms this) during pregnancy, the product can eliminate the problem of false positive results in relation to hepatitis C. In addition, during the bearing of a child, "Essentiale" stops manifestations of toxicosis, maintaining the normal state of he alth of a woman.
Separately, it should be emphasized the reviews about "Essential", which relate to the use of the product in order to restore liver function against the background of overeating, taking antibiotics, excessive consumption of alcohol and other drugs, and in addition, to eliminate bitterness in the mouth, pain in the right hypochondrium and in the fight against lack of appetite. In these reviews, we are talking about the fact that people feel better, stool normalizes, pain and rashes on the skin disappear. In addition, it is noted that the appearance of appetite is fixed some time after the start of Essentiale therapy, which occurs at least two to three weeks later.
Negative reviews of "Essential" are quite few and are due to two main factors - the lackthe expected clinical result or the conviction of buyers that this drug is a relatively old drug, since at the moment there are much more effective hepatoprotectors. We have reviewed instructions for use for Essentiale in ampoules.
