Many people in the world suffer from various types of allergies. For some, it is almost asymptomatic or worsens only at certain times of the year or under certain weather conditions. For other people, allergies prevent them from living day and night, making existence without the necessary drugs simply impossible.
Familiarization with the instructions for the use of Diphenhydramine in ampoules
Allergy is an acute reaction of the human immune system to substances that are safe in nature and are constantly in widespread use. Just at one point, the immune system begins to attack the human body.
Allergy symptoms can occur when an allergen is inhaled or comes into contact with the skin, or when it is eaten. A rash and hives appear on the skin, tears flow from the eyes, breathing becomes difficult, sneezing and a runny nose appear. These symptoms may last for several hours and sometimes for several days. To alleviate the patient's condition and improve his quality of life, the drug "Dimedrol" in ampoules is widely used to combat allergic manifestations.
Medication description
"Diphenhydramine" ("Diphenhydramine") is a drug aimed at alleviating allergic symptoms in adults. It was first discovered in the 40s of the last century by a former professor at the University of Cincinnati, George Riveschl, and already in 1946 was released for sale as the first antihistamine drug approved by the FDA in the United States. The drug is a life-saving drug.
Issue form
"Dimedrol" is available in ampoules as a 1% solution for injection. One ampoule of the drug contains 10 mg of diphenhydramine. The drug is packed in a cardboard box of 10 ampoules. This dosage form is convenient for intramuscular or intravenous administration in situations where the usual tablet form cannot be taken due to severe vomiting or because the patient is unconscious.
The action of "Dimedrol"
"Dimedrol" eliminates the symptoms of allergic reactions by blocking H1-histamine receptors. The drug quickly stops spasms of smooth muscles, reduces swelling of the tissues of the mucous membranes, as well as redness of the eyes and skin, itching and capillary permeability.
"Dimedrol" provides local anesthesia of the larynx and oral cavity, if taken orally. The drug can reduceblood pressure, as well as have a calming or even hypnotic effect. "Dimedrol" in ampoules begins to act a few minutes after ingestion and continues to act for about 4-8 hours. It is excreted from the body in full with the help of the kidneys during the day.
Indications for the use of "Dimedrol" in ampoules
Usually the drug is used in the following cases:
- anaphylactic shock;
- allergic eye inflammation;
- urticaria;
- hay fever;
- angioedema;
- allergic to other drugs;
- serum sickness;
- capillarotoxicosis;
- Ménière's disease;
- dermatitis and itching;
- chorea;
- postoperative vomiting;
- polymorphic exudative erythema.
Method of application and dosage
Before use, you must carefully read the instructions for use. "Dimedrol" in ampoules for adult patients, experts recommend administering intravenously as a dropper or intramuscularly. Under the skin, the drug should not be injected due to the occurrence of severe inflammation around the injection site. When using it intramuscularly, a single dose of "Dimedrol" in ampoules is from 10 to 50 mg (1-5 ampoules), the maximum allowable dose per day should be no more than 150 mg (30 ampoules).
For intravenous drip, drugs are mixed in proportions of 20-50 mg of "Dimedrol" per 100 ml of 0.9% sodium chloride solution. Treatment continues untilpositive effect and provided that there are no adverse reactions to the drug. It is necessary to store "Dimedrol" in ampoules in the refrigerator or in any other dark place, out of the reach of children, at a temperature not exceeding +25 °C. The shelf life of the drug is no more than four years from the date of its release.
Symptoms of drug overdose
If the patient does not properly observe the dosage of "Dimedrol" in ampoules, quite unpleasant and sometimes life-threatening symptoms may occur:
- heaviness in the chest when inhaling;
- dry mouth;
- facial redness;
- excited state;
- euphoria or, conversely, a depressive state;
- confusion of thoughts;
- heart rhythm disorder;
- cramps in limbs.
When treating an overdose of "Dimedrol" in ampoules, it is necessary to take into account the manifestations of symptoms. If respiratory failure occurs, monitoring of respiration and blood pressure is necessary. Intravenous infusion of a blood-substituting fluid to purify the blood. "Physostigmine" - a drug that stops the action of diphenhydramine, is administered intravenously, if necessary, repeated administration is possible. For convulsions and seizures, the use of "Diazepam" is necessary.
Side effects
- From the side of the general physical condition, weakness, reduced attention, decreased speed of reactions and coordination of movements, headaches and dizziness, tinnitus, panic attacks may occur.attacks, irritability, agitation, dilated pupils or blurred vision, tremors or cramps in the limbs, insomnia.
- In the area of the cardiovascular system, when using "Dimedrol" in ampoules, a heart rhythm disturbance, low blood pressure may occur.
- On the part of the hematopoietic system: anemia, a decrease in platelet count in the blood.
- From the digestive system: nausea, numbness and dryness of the mucous membranes in the mouth, vomiting, constipation, diarrhea, pain in the stomach.
- Side effects in the genitourinary system: urinary retention or, conversely, constant urge to urinate, menstrual cycle disorders.
- On the part of the respiratory system, there is a sore throat, the formation of crusts in the nose, a feeling of pressure in the chest, nasal congestion, shortness of breath.
- When using "Dimedrol" in ampoules on the skin, symptoms such as redness, itching, multiple rashes, ulcers on the skin and mucous membranes may appear.
- Allergic reactions to the drug itself may also occur, resulting in the following symptoms: hives, rash, anaphylactic shock. Chills and fever possible.
To avoid unpleasant and dangerous consequences of an overdose, you must strictly follow the instructions of doctors and the recommendations described in the instructions for "Dimedrol" in ampoules.
Contraindications
"Dimedrol" in ampoules is undesirable to take with the followingdiseases and characteristics of the body:
- hypersensitivity to the composition of the drug;
- stomach disease;
- angle-closure glaucoma;
- epileptic seizures;
- pregnancy I, II, III trimesters and lactation;
- bradycardia;
- porphyria;
- bronchial asthma;
- arrhythmia;
- perinatal long QT syndrome or systemic medication that prolongs the QT interval;
- under 18 years of age;
- pheochromocytoma.
Special Instructions
The drug "Dimedrol" in ampoules is not used subcutaneously due to tissue necrosis.
The drug is used with particular attention in patients who have recently had diseases of the respiratory system, suffering from hyperthyroidism, as well as in people with low blood pressure, diseases of the cardiovascular system and increased eye pressure. Due to the possibility of such undesirable effects as hallucinations, dizziness, etc., under special control, "Dimedrol" in ampoules should be used for elderly patients in order to avoid falls and injury.
It is necessary to use the drug with caution in patients suffering from disorders in the functioning of the kidneys and liver. During the use of Dimedrol, it is necessary to refrain from drinking drinks containing alcohol. Do not stay in direct sunlight. When contacting the hospital, the patient must necessarily inform the doctor that he is taking Dimedrol. This information will help in diagnosing various diseases.
It was revealed that "Dimedrol" has a number of effects that reduce the speed of reactions, attentiveness, and has strongly pronounced sedative properties, therefore, when using this drug, you should not engage in activities that pose a potential danger, requiring special care and reaction, in particular and driving.
Synonyms of "Dimedrol"
The word "synonym" refers to drugs that contain the same active ingredient. These drugs include all drugs that contain diphenhydramine:
- "Psilo Balm".
- "Grandeem".
- "Allergin".
- "Dimedrol-UBF".
- "Diphenhydramine hydrochloride".
- "Diphenhydramine Bufus".
- "Dimedrol-Vial".
Analogues
An analogue of "Dimedrol" in ampoules can be any drug with active ingredients of different composition, but with the same properties and pharmacological action:
- "Suprastin".
- "Loratadine".
- "Desloratadine".
- "Fencarol" etc.
In addition, many of the analogues of "Dimedrol" can be purchased at a pharmacy without a prescription.
Drug Interactions
"Diphenhydramine" can enhance the effects of various drugs. For example:
- drugs used for anesthesia;
- sedatives and sleeping pills;
- preparations for local anesthesia;
- various analgesics, including narcotics.
Concomitant use with analeptics may cause seizures.
Use together with MAO inhibitors can increase blood pressure and adversely affect the respiratory and nervous system. "Dimedrol" in combination with drugs to reduce pressure increases the feeling of fatigue. It reduces the effectiveness of the emetic "Apomorphine", which is used in the treatment of poisoning. "Dimedrol" in ampoules should not be administered simultaneously with drugs that contain diphenhydramine, in order to avoid overdose symptoms.
It is forbidden to mix the drug with other medicines in the same container. Use only the diluent recommended for this medication.
Terms of dispensing from pharmacies
The most significant quality of "Dimedrol" in ampoules is its rather low cost - within 20 rubles per package.
"Dimedrol" is not a narcotic substance, but due to its sedative effect on the central nervous system, it is in great demand among people suffering from drug addiction. Sometimes the drug can have a reinforcing effect from alcohol and drugs. That is why without a prescription "Dimedrol" in ampoules in pharmacies cannot be purchased. The best thi-g.webp
