In the article we will consider the instructions for the use of "Kabiven" - a drug for nutrition by intravenous infusion.
There are many different diseases that lead to extremely serious consequences and require long-term inpatient treatment. So, some patients cannot eat food on their own, which is why they need the use of special drugs. The drug "Kabiven Peripheral" is a complex that replenishes the protein and energy insufficiency of the body. It contains all the minerals and essential amino acids to normalize the metabolic process. It is a good parenteral nutrition product.
Characteristics of this drug
The drug "Kabiven Peripheral" differs in that it consists of three components in a balanced ratio. He is distinguished by:
- The presence of vamin, which acts as an amino acid solution with maximum biological value.
- Presence of intralipid, which is a fat emulsion with an unsurpassedsecurity. It is worth noting that this is the most commonly used fat emulsion in Europe.
- Presence of 11% glucose.
Pharmacological effect of this drug
According to the instructions for use for Kabiven, the therapeutic effect of this drug is due to the combination of its constituent properties. The substance intralipid makes up for the lack of fatty acids and contains the required amount of phospholipids, which help to provide the body with energy reserves. Vamin 18 Novum is a complex of amino acids and minerals. In turn, proline, which is part of this complex, is necessary for tissue repair after injury and surgery. It promotes the production of collagen and other structural components.
The alanine component is an amino acid involved in glucose metabolism. This acid stimulates the release of glucose from glycogen stores, preventing the development of hypoglycemia.
Methionine is a powerful antioxidant. They prevent the destruction of cells by free radicals. This component can bind toxins, accelerating their removal from the body. Glycine is required to restore brain function. This amino acid is involved in the transmission of nerve impulses and metabolic reactions occurring in the nervous system.
Sodium, in turn, takes part in the transport cellular work designed for the process of ion exchange. Calcium is required for workmany enzymatic systems. Glucose (11% solution) takes part in any metabolic processes and acts as the main energy substrate, which is necessary for the he althy functioning of organs and systems.
What is the composition of this drug
The Kabiven Peripheral medical product contains intralipid, which replenishes fat reserves in the human body.
The energy substrate in question contains an eleven percent glucose solution.
The main source of minerals and amino acids in Kabiven Peripheral is the vamine complex.
This medicinal product comes packaged in a plastic three-chamber container, the contents of which are administered to the patient intravenously. Next, we will consider the indications for the use of this medication.
Indications for the use of medication
The indication for the use of "Kabiven Peripheral", as a rule, is the need to provide the patient with parenteral nutrition, bypassing the gastrointestinal tract. It is also used to treat protein and energy deficiencies that accompany many different diseases. Now let's find out what side effects this drug has.
Side effects of this drug
Side effects of a parenteral nutritional product can be manifested in the form of allergic reactions, hypertension, hypotension, and, in addition, in the form of headache or abdominal pain. Development is possible at the injection sitethrombophlebitis.
Compliance with the rules of the instructions for using the "Kabiven" tool will minimize unwanted manifestations.
Contraindications are the following pathologies: the presence of hyperlipidemia, kidney failure, impaired liver function and blood clotting.
Side effects of "Kabiven Peripheral" are described in detail in the instructions.
Pregnancy and lactation: is it safe to take?
No studies have been conducted to date to obtain information about the effect of the drug in question on the body of pregnant women and infants. Pregnancy along with lactation are a relative contraindication. The use of this medicinal product for this category of women is justified only in the case of an obvious predominance of the therapeutic result over the possible risks.
Instructions
Kabiven is prescribed as an infusion treatment, it is injected into peripheral veins. The dosage of the drug in question depends on the general degree of depletion of the patient and his natural nutritional requirements. Immediately before use, it is required to remove the clamps and mix the contents of the chambers. The speed of the infusion is determined by the doctor, taking into account the severity of the condition of a particular patient.
The maximum daily dose is 40 ml/kg/day for an adult. Children from two to ten years old need 14-28 ml of the drug per kilogram of body. Children over 10 years oldadminister doses as for adults. The rate of administration of the drug should not exceed 3.7 ml/kg/h.
Features of use
The dosage of this product directly depends on the purpose of use. During periods of admission, it is necessary to monitor the patient's blood clotting index. When mixing solutions, it is necessary to adhere to the rules of asepsis in order to prevent infection.
Interaction with alcohol
The therapeutic agent in question is used as part of parenteral nutrition for medical support of seriously ill patients. In a hospital setting, the use of alcoholic beverages is prohibited.
Compatibility with other medicines
It is worth noting that the medical drug "Heparin" affects lipid metabolism. This agent can accelerate or inhibit lipolysis. Insulin has similar properties.
The drug "Kabiven Peripheral" can be combined with other drugs only under the supervision of a doctor. It penetrates the bloodstream and is characterized by systemic manifestations.
Overdose
Against the background of the intake of this solution in the body in high dosage, patients may experience a syndrome of fat overload, expressed in hyperlipidemia. Also, the appearance of a reaction in the form of agranulocytosis, thrombocytopenia, an increase in temperature and in the form of the development of hepatomegaly is not excluded. Subsequently, a coma may occur. Therapeutic techniques consist in the complete cessation of the infusion and the elimination of unwanted symptoms.
Similar drugs
The products intended for parenteral nutrition include "Alvezin", which contains a complex of microelements and amino acids. Among group analogues, it is worth noting medical preparations in the form of Lipofundin, Aminosol, Intralipid. All of these medicines have a similar composition.
Terms of sale
A medical product called "Kabiven Peripheral" is intended for the treatment of patients in a hospital. It is worth emphasizing that this remedy is not available for purchase in regular pharmacies.
Reviews about "Kabiven Peripheral"
The medication in question is intended to replenish amino acid deficiency and various trace elements in patients. Often this tool is used by resuscitators, who in their reviews indicate an improvement in the general condition of patients, and, in addition, to accelerate the healing process. Relatives of seriously ill people are also seeing progress in their treatment after using this medication.
Storage rules
"Kabiven" is stored at a temperature that should be less than twenty-five degrees. Provided that the integrity of the packaging is preserved, this medicinal product is suitable for use for two years from the date of issue. Immediately after opening and mixing the ingredients, it is permissible to store the medicine for twenty-four hours at a temperature of about twenty-five degrees.
Ingredient of the drug "Kabiven"
L-tyrosine is a propionic acid. It is classified as an aromatic alpha-amino acid. In structure, this compound may differ from phenylalanine by the presence of a phenolic hydroxyl group in the position of the benzene rings. From a biological point of view, less important metaisomers of L-tyrosine are known.
Intralipid substance as an ingredient of the drug
Intralipid component (20%) is a source of energy, and in addition, essential fatty acids. This substance contains refined soybean oil along with emulsified phospholipid-purified egg yolk. Soybean oil, in turn, consists of a mixture of predominantly fatty polyunsaturated acids. Phospholipids are isolated from egg yolk. The sizes of lipid globules, along with the biological properties of intralipid, are identical to those of chylomicrons. The pharmacokinetics of this ingredient has not been studied.
Vamin component as an ingredient of the drug
Indication for the use of this substance is the parenteral nutrition of patients with a significantly increased need for protein. Contraindications to the use of this substance are the presence of hypersensitivity in the patient along with liver failure and uremia (in the absence of the possibility of dialysis).
It is worth noting that simultaneously with the infusion of vamin, an intralipid or dextrose solution is administered, since an increase in calories can contribute to the optimal degree of utilization of amino acids, and the risks of developing thrombophlebitis decrease from concentration dilutions. Learn more about the benefits of thisfunds.
Drug Benefits
The advantages of the described medical device are the following advantages:
- Having an optimally balanced composition.
- Manufacturability along with convenience and ease of use.
- Reduce the risk of infectious complications.
- Possibility to add vitamins along with trace elements and Dipeptiven thanks to the use of a special port.
- Possibility of introducing a therapeutic agent into the central, and in addition, into the peripheral veins.
Medication for parenteral nutrition
Parenteral nutrition is used when it is forbidden to meet the needs of the body in a natural way, that is, habitual feeding through the mouth or through the use of a probe. General medical indications for this are toxic conditions in the form of coma, intractable vomiting, extensive burn lesions, multiple and combined injuries, maxillary and facial injuries, after operations on the organs of the digestive system, as well as at the stage of the early postoperative period.
Parenteral nutrition is either complete or partial. Patients need to meet their body's needs for energy, amino acids, essential fats, minerals and vitamins. But such a universal drug, unfortunately, does not exist; therefore, a combination of different solutions is used for parenteral nutrition. Carbohydrates serve as the main source of energy: 1 gram of glucose provides the body with 4.1 calories.
5% glucose solution is a form of isotonic solution. But it is worth noting that 100 milliliters of this solution contains only 20 calories. In order to meet the daily energy requirement, 12 liters of such a solution are required. Therefore, concentrated glucose solutions of ten, twenty and thirty percent format are used.
There are many different diseases that lead to serious consequences and require long-term inpatient treatment. Some patients are simply unable to eat on their own, and against this background, there is a need to use funds intended for parenteral nutrition. The drug called "Kabiven" is just a complex that replenishes protein and energy deficiencies. It contains all the necessary amino acids along with minerals to normalize the metabolic process in the body.
