Acne spares no one and affects the skin of both girls and boys, and people at a more mature age. To remove them, use different drugs, including Klenzit S. From acne, reviews testify to this, the drug cures effectively, but the result appears only after prolonged use.
Composition of the drug
The active ingredients are:
- adapalene, which is a retinoid, that is, a synthetic analogue of retinoic acid, 1 mg per gram of Klenzit C acne gel;
- clindamycin at a ratio of 10 mg per 1 gram of the drug.
Auxiliary components:
- propylene glycol;
- disodium edetat;
- Carbomer 940;
- sodium hydroxide;
- purified water;
- methyl parahydroxybenzoate;
- phenoxyethanol;
- poloxamer 407.
The medicine is only forexternal use, packaged in tubes of 15 and 30 grams. The manufacturer is Glenmark Pharmaceuticals Ltd (India).
The active ingredient adapalene is also present in a number of similar preparations aimed at eliminating acne, these are:
- "Klenzit";
- Differin;
- "Adapalene";
- "Adolen-gel";
- Adaclin.
The drug is characterized by anti-inflammatory, anti-comedogenic, bacteriostatic properties. It is often used not only for resorption of deep acne, comedones, but also to eliminate inflammatory processes. The skin after its application is cleansed, closed and open acne disappears, metabolic processes in the skin layers and cell regeneration take place faster. It is often recommended for the treatment of acne vulgaris.
Pharmacodynamics
Acne remedy "Klenzit" refers to combined preparations, where the active ingredients are adapalene and clindamycin.
Adapalene as a retinoid derivative acts on the skin as an anti-inflammatory and comedonolytic agent. Works on both open and closed comedones. Restores epidermal differentiation and keratinization. It slows down the binding of follicular particles of the epidermis, which prevents the occurrence of acne. Significantly slows down the chemokinetic reactions of the dermis and chemotaxis of polynuclear cells of the skin.
Clindamycin contained in the preparation"Klenzit C" from acne, the instruction refers to lincosamides. It is a semi-synthetic antibiotic. Its bacteriostatic activity is observed against a number of microorganisms, for example, such as cocci and anaerobic. Has a connection with the 50S subunit of ribosomal membranes, significantly reduces protein replication in a pathogenic cell. It is characterized by a bactericidal orientation to some types of gram-positive cocci.
Adapalene in combination with clindamycin increases the effectiveness of the drug and better eliminates inflamed skin. Ongoing tests have shown the unique compatibility of these two substances.
Absorption of the drug in body tissues with local use is negligible.
Ointment "Klenzit" from acne, as practice has shown, effectively removes acne and prevents the formation of new comedones. Evens out the surface of the skin, improves its appearance.
The action of the remedy "Klenzit C" from acne
Reviews suggest that the effective effect of this product on the skin is based on the quality components of retinol, and therefore:
- reduces the release of fat on the surface of the epidermis by reducing the secretion of the sebaceous glands; this process does not allow the skin ducts to become clogged and prevents the formation of comedones;
- the percentage of propionic acne microbes is reduced by reducing greasiness in the dermis;
- fatty plugs in the pores dissolve, resulting in clearer skin;
- restores the process of formation of new keratinized cells, which prevents the emergence of new particles in large quantities in the layers of the epidermis, therefore the pores become less clogged, and comedones do not multiply;
- the drug is an excellent antiseptic and quickly removes the inflammatory process;
- protective functions of the skin are restored, sebum-fat metabolism in cells improves.
Indications and contraindications
The gel is indicated for external use in the event of acne of various manifestations and forms of severity.
A contraindication to the use of the gel is intolerance to adapalene and other components in the composition of the drug, as well as hypervitaminosis A and combined use with other drugs that include retinol. The prohibition is also a violation of the integrity of the skin, that is, the presence of wounds, burns and other damage to the skin. You can not use it during pregnancy and lactation, despite the fact that only 4% of the drug is absorbed in the body, and subsequently excreted in the bile. In this case, Klenzit C, like any other antibiotic, can negatively affect the development of the fetus.
Use with caution with products that cause excessive dryness of the epidermis, as well as with eczema and dermatitis. After applying the Klenzit C acne gel, reviews of which are simply excellent, you can not visit the solarium the day before the application procedure and for one day after.
Side effects of the drug
Bin a number of cases, the occurrence of side effects due to the use of the drug "Klenzit" is observed. Acne gel, reviews of which are the most positive, can provoke severe dryness of the skin, as well as cause itching, burning, flushing, irritation and redness. If such a situation occurs, you should temporarily suspend the use of the drug and continue the therapeutic course after the complete disappearance of side effects.
Frequently there is peeling. It occurs as a result of the action of retinoids on the skin. In this case, it is recommended to lubricate the surface of the skin with a moisturizer 30 minutes after applying the drug.
Sometimes there is an exacerbation of acne, which disappears during the treatment. There have been cases of allergy to the drug and individual intolerance to the drug, but such situations were rarely observed.
"Klenzit C" for acne: instructions for use
The product is for external use only. The drug is applied only to acne and is not rubbed. The ointment is not used on skin that has damage, abrasions, scratches or burns. At the beginning of treatment, the gel may cause more active acne. But you should not stop therapy, as the process of deep cleaning of the dermis takes place, at this time the Klenzit drug pushes everything unnecessary from the pores to the surface of the skin, so acne appears more actively.
The product is applied to the inflamed area and dotted 1-2 times a day. If applicationreduced to one time, it is recommended to apply "Klenzit" immediately before going to bed. Acne gel, reviews of which are impressive, should be applied to the surface of the skin thoroughly cleaned of dirt and dust. If the use of the drug falls on the daytime, then for two hours after applying the ointment, you should not wash your face and apply cosmetics. The course of treatment and the scheme of using the drug is prescribed and controlled by a cosmetologist. On average, the therapeutic period lasts from 4 to 8 weeks. If necessary, the period is extended, but no more than 3-4 weeks.
The drug can be addictive, causing bacteria to become less sensitive to its effects, so if acne does not disappear after the specified time, then treatment should be continued with other drugs.
Features of using the gel
"Klenzite" for acne is a medicine, and therefore it should be used with caution and only after consulting a doctor. Also, while using it, you should follow certain recommendations:
- try to apply the gel directly to the affected area without touching he althy skin;
- carefully ensure that the product does not get into the eyes and mucous membranes of the nasal and oral cavity;
- do not apply the drug to injured skin that has abrasions, burns, scratches;
- be sure to wash your hands after applying the drug;
- in case of excessive dryness of the dermis, you should use Panthenol or Bepanthen;
- not worth ituse "Klenzit C" in sunny hot weather, since during this period the skin is especially defenseless and exposed to aggressive ultraviolet rays;
- when the skin is peeling, use any moisturizer for the face;
- do not apply the ointment if irritation occurs, with severe redness or allergic reactions.
Overdose and drug interactions
Local use of the drug almost completely eliminates overdose. In case of accidental ingestion of the gel, experts recommend immediately rinsing the stomach and drinking enterosorbents.
Klenzite C should not be combined with alcohol-containing (ethanol-containing) products, such as lotions, colognes, eau de toilette. Also, for the period of treatment, it is worth abandoning creams that have a drying, irritating effect. During this period, you should not use drugs that include calcium gluconate, aminoglycosides, ampicillin, magnesium sulfate and a vitamin complex of group B.
Often the gel is used in complex therapy with products containing benzoyl peroxide. Usually, only Klenzin S is prescribed for one or two weeks, and then a more gentle treatment for the skin is prescribed. For example, in the morning "Baziron AS" (the active substance is benzoyl peroxide), and in the evening "Klenzit", containing only retinoid, without adding the antibiotic clindamycin.
When using the drug "Klenzit C" simultaneously with erythromycin, the effectivenessthe impact of the former is greatly reduced.
Which do you prefer: "Klenzit" or "Klenzit C"
Preparations "Klenzit" and "Klenzit S", despite the similar name, are radically different in their effects. The first contains one active ingredient - adapalene. It is often used for minor inflammatory processes on the face, enlarged pores, small acne. The product has an excellent comedolytic property.
"Klenzit C" contains in its composition not only adapalene, but also the antibiotic clindamycin in the proportion of 10 ml per 1 gram of gel. Therefore, it is often used for severe pustular inflammation on the face, when one component of the retinoid is unable to cope.
Which remedy for acne treatment to choose is an individual question. In any case, before using this or that drug, it is better to consult a specialist. After all, only then can you be sure of the correctness of the chosen solution.
"Klenzit C" and "Klenzit" for acne can be purchased both in a regular pharmacy and on Internet resources. The cost of the drug varies depending on the place of sale and starts from 350 rubles for a tube of 15 ml.
The drug is available only on prescription. The drug should be stored in a dark, cool place out of the reach of children, at a temperature not exceeding 25 ° C.
Medication has a two-year shelf life.
Reviews about the drug
The remedy for acne "Klenzit" caused a lot of conflicting reviews. For some, it has become a real panacea, and aftera few days the result was noticeable. Someone felt the effectiveness of the drug after 3-4 weeks of use.
The number of acne and comedones has noticeably decreased in these people. The skin of the face was evened out. During treatment, some people complained of excessive dryness of the skin and peeling. Some have since stopped using it altogether. Others switched to an alternate-day drug regimen.
There is a category of women who lubricated the places of peeling with a moisturizing or nourishing cream. But, as a rule, peeling is observed only at the initial stage of treatment, while the skin adapts to the influence of the drug, and such phenomena are practically not observed in the future. Undoubtedly, they are evidence that the drug "Klenzit C" from acne is effective, reviews. Photos before and after its application just confirm this.
But not everyone is happy with the result of the treatment. In some individuals, both at the beginning of treatment and later, there was a strong reddening of the skin, peeling, profuse acne and a marked increase in the number of comedones. They had to stop using the drug and replace it with another drug. There have also been known cases of allergic skin rashes.
A certain category of citizens used "Klenzit C" for acne on the back. Here the effectiveness of the drug was on top. This area of the body is not as sensitive as the skin on the face, so almost no one experienced any side effects.
Women with acnecapable of doing anything to get rid of it. For these purposes, often the most powerful drugs are used, since they act quickly and efficiently. But it is advised to use these remedies for the treatment of acne with an antibiotic in the case when other remedies have not helped.
The drug, which we considered in our article, cleared more than one face from acne. Even more effective results were shown by "Klenzit" from acne on the back. It should also be noted that spot application may not bring the desired effect, since in this case the medicine only affects acne, but should also affect the area adjacent to acne.
