In our time, a huge number of people suffer from allergic diseases. They can appear in completely different ways. Someone starts a long rhinitis, someone is tormented by rashes all over the body, and someone cannot cope with their cough. There are many drugs against this disease, they all have their own characteristics of use and indications for use. One of these drugs is Alerzin. The instruction attached to it contains a detailed description of indications and contraindications.
Composition of the drug
"Alerzin" is available in two dosage forms: in the form of tablets and drops. If we consider drops, then 1 ml of the drug includes:
- 5mg levocetirizine dihydrochloride is the main active ingredient.
- As auxiliary substances there are: 85% glycerin, sodium saccharin, propylene glycol, sodium acetate trihydrate, propyl parahydroxybenzoate, glacial acetic acid, methyl parahydroxybenzoate,purified water.
1 tablet also contains 5 mg of the active substance, and as additional components are included:
- Microcrystalline silicon cellulose.
- Lactose monohydrate.
- Low substituted hydroxypropyl cellulose.
- Magnesium stearate.
Drops are available in 20 ml bottles, and tablets are available in packs of 7-14.
Pharmacological action and pharmacodynamics
According to its properties, the drug belongs to antihistamine drugs. The main active ingredient, if we consider Alerzin (drops), the instructions for use describe it as capable of blocking histamine receptors.
The effect of the drug is possible due to:
- Reduce vascular permeability.
- Reduce eosinophil migration.
- Limiting the release of inflammatory mediators.
The active substance of the drug does not allow the development of allergic manifestations, due to the fact that it has the following properties:
- Antiexudative.
- Anti-inflammatory.
- Anti-irritants.
Intake of the drug inside leads to its rapid absorption into the bloodstream, and this process is practically independent of food intake. The bioavailability of the drug is 100%.
Effectiveness appears in some patients within 12-15 minutes after administration, in most - after half an hour or an hour. Accurate distribution informationthere is no substance in the tissues of the body.
Indications for use of the drug
Regarding Alerzin, the instruction contains information on indications for use. It is usually recommended in the following situations:
- Treatment of symptoms in patients who suffer from chronic idiopathic urticaria.
- As a remedy for rhinitis caused by allergens.
The list of indications is small, judging by the information that the instruction reports about Alerzin. Reviews about it are quite good, if you follow all the doctor's recommendations for use.
Who should not take Alerzin
No matter how good the drug is, it always has contraindications. At Alerzin they are as follows:
- Do not take medicine to patients with severe kidney disease.
- Do not prescribe the drug during breastfeeding.
- If there is an individual intolerance to the components of the drug.
- During pregnancy.
- If lactose intolerant.
- Have galactose intolerance or impaired absorption of glucose and galactose, but only in tablet form.
- Be especially careful when prescribing to elderly patients.
"Alerzin": instructions for use
Given the different form of release of the drug, the dosage and treatment regimen will vary. These nuances must be checked with a doctor.
If Alerzin (drops) is prescribed,the instruction recommends taking them orally, not taking into account food intake. You can use the drug both in pure form and diluted with water. Diluted drops should not be stored and should be consumed immediately.
Dosage is determined by the doctor, but usually it is 5 mg once a day.
If the pharmacy offers you "Alerzin" (tablets), the instruction recommends taking them whole with water. The dosage is also 5 mg or 1 tablet per day.
Duration of treatment
If allergic rhinitis occurs periodically and lasts from 4 days to a month, then Alerzin therapy must be coordinated with the characteristics of the course of the disease. Often, when symptoms disappear, treatment can be stopped, and if they occur, they can be resumed again.
If allergic rhinitis lasts more than a month as a result of constant contact with allergens, then therapy may be permanent. In the chronic form of urticaria and rhinitis, treatment with Alerzin can last about a year.
Side effects of the drug
Not all patients tolerate the effects of this drug well. Everyone's body is different, so you can expect some side effects that can affect many organ systems:
1. Breathing may cause shortness of breath.
2. The nervous system may respond with the following symptoms:
- Sleep disturbance.
- Headache.
- Fatigue.
- Increasedarousal.
- Weakness.
- Asthenia.
- Convulsions.
- Dizziness to the point of fainting.
- Tremor of limbs.
- Hallucinations.
3. From the side of the cardiovascular system, an increased heartbeat and tachycardia can be observed.
4. The urinary system will show its failure in the form of urinary retention, dysuria.
5. Visual disturbances may occur.
6. Gastrointestinal disorders such as nausea, diarrhea, constipation, dry mouth, hepatitis.
7. Myalgia.
8. Rashes may appear on the skin, itching worries, in some situations - Quincke's edema.
9. Rarely, there may be swelling, increased appetite, weight gain.
If any undesirable manifestations appear during Alerzin therapy, it is worth visiting a doctor and discussing further treatment with him.
High doses of drug
Some mistakenly believe that an increased dosage will give a faster positive effect and exceed the norm of taking the medicine. This leads to an overdose of the active substance in the body, which can provoke:
- Drowsy.
- Increased irritability.
- Nervous excitement.
All these manifestations will depend on the amount of the drug taken in excess of the norm. In case of an overdose, it is necessary to empty the stomach, and then eliminate the symptoms that appear.
Interaction with other drugs
We have considered the drug "Alerzin",instructions, the price for it is quite acceptable, but it is necessary to discuss with your doctor the combination of the drug with other drugs, if you use them, before use.
Many years of laboratory tests have established that the joint use of "Alerzin" and "Antipyrin", "Glipizide", "Erythromycin", "Diazepam" does not give negative consequences.
If you combine the drug and treatment with "Ritonavir", then the distribution of the latter throughout the body is reduced by 10-12%.
Combined use with "Theophylline" reduces the clearance of levocetirizine, but the kinetics of "Theophylline" does not change. During the period of therapy with Alerzin, the use of sedatives is not recommended, although no increase in their effect was observed when using therapeutic dosages.
Some instructions during treatment with Alerzin
The doctor, before prescribing any drug, must conduct a thorough examination of the patient. This also applies to completely safe means, which include Alerzin. In the presence of concomitant diseases, the dosage and treatment regimen should be adjusted.
Carefully take the drug should be patients with pathologies of the excretory system, especially for elderly patients with CRF.
If a patient has a spinal cord injury, prostate adenoma, it is necessary to adjust the dose of the drug, as it can provoke urinary retention in the body.
Some components of "Alerzin" can cause allergic manifestations, so patients,those suffering from excessive susceptibility to various factors should be careful during treatment.
Use of the drug in childhood
Used for the treatment of allergic rhinitis or urticaria in babies should be used only after consultation with the Alerzin doctor. The instructions for children do not recommend using it for treating babies under 6 months old.
The dosage of the drops will depend on the age of the child:
- From 6 to 12 months a day, you can take 5 drops of the drug once.
- From 1 year to 6 years "Alerzin" (drops) instruction for children recommends giving 5 drops 2 times a day.
- Children over 6 years of age, the dosage is 5 ml once a day.
It is strictly forbidden to give pills to children under 6 years of age. After 6 years, a dose of 5 mg per day, which equals 1 tablet.
Use of "Alerzin" during pregnancy and lactation
Women in an interesting position are practically not prescribed "Alerzin", the instruction does not contain reliable facts about the safety of levocetirizine for fetal development.
If there is a need to take the drug during breastfeeding, then it should be stopped.
Analogues of the drug
Alerzin has a fairly large number of analogues, they have a similar therapeutic effect, therefore, if there are contraindications to its use, then it is worth discussing this issue with a doctor.
Among analogues, the following can be mentioned:
- Allertec.
- Zestra.
- Zodak.
- Zyrtec.
- Rolinose.
- Cetrin.
- Cetirinax.
If there are no contraindications to taking Alerzin, then you need to discuss with the doctor whether it can be replaced with an analogue. In some cases, it is better to use one that has already been tested and is working.
Reviews about the drug
Alerzin (drops) has already been reviewed in detail, instructions. The price of the drug is relatively small (about 330 rubles), so most patients can afford to buy it. Feedback on the treatment of this medicine is positive, this is due to the fast action, convenient use and high efficiency.
Some patients who use the medicine periodically note one drawback - this is a short shelf life after opening the vial with drops.
Allergies have rather unpleasant manifestations that you want to get rid of quickly. Pharmacy shelves are full of antihistamines, but it is better to entrust the choice of medicine to a specialist, and not self-medicate, then the effect will be guaranteed.
