"Phenazepam" refers to drugs with anti-anxiety activity with sedative, hypnotic, anticonvulsant and muscle relaxant action. You should take the drug only as prescribed by the doctor and clearly know whether Phenazepam can be absorbed under the tongue.
The action of the drug and its properties
"Phenazepam" is a tranquilizer with high activity and a particularly pronounced anti-anxiety effect. In addition, the drug has a hypnotic-sedative, muscle relaxant and anticonvulsant effect. This is due to the stimulation of benzodiazepine receptors located in the brainstem and lateral horns of the spinal cord, and an inhibitory effect on subcortical structures and spinal reflexes.
Anti-anxiety action is characterized by relieving tension, fear and restlessness. It has no particular effect on delusional symptoms and hallucinations. Accelerates and improves the mechanism of entering the sleep phase.
The drug stops convulsions, causing inhibition of the transmission of nerve impulses.
The maximum concentration of the active substance in the body occurs within an hour or two after ingestion. The drug undergoes transformations in the liver cells and is excreted by the kidneys. It has a long half-life of 6 to 18 hours.
Indications for use
"Phenazepam" to swallow, take under the tongue or inject - the specialist decides depending on the disease and the severity of the condition.
The drug is indicated for:
- Neurotic disorders accompanied by severe anxiety and agitation (panic, generalized disorder, phobias).
- Mood disorders accompanied by anxiety (Mixed Anxiety-Depressive Disorder, Depression).
- Disorders of adaptation.
- Somatoform disorders accompanied by fears and anxiety.
- Obsessive-compulsive disorder with obsessive thoughts and actions.
- Sleep disorders.
- Withdrawal from alcohol or drug withdrawal.
- Epileptic seizures, up to epistatus.
- To help fight fear in extreme conditions.
- For premedication before anesthesia, as one of its components.
How to take "Phenazepam": under the tongue or inside?
Doctors, prescribing the drug, clearly stipulate the dosage and timing of administration. "Phenazepam" to drink or dissolve this medicine under the tongue, the patient can check withdoctor without a shadow of embarrassment. The tablet is made in such a way that it dissolves well in the gastrointestinal tract. Medicines such as Phenazepam do not need to be taken under the tongue due to the longer dissolution of the drug in the oral cavity and, accordingly, a longer wait for the effect.
For insomnia, take 1/4 - 1/2 tablet half an hour before bedtime.
For the treatment of neuroses 1/2 - 1 tablet is taken up to three times a day. Maximum dose 6 tablets (6 mg).
For the treatment of epileptic seizures, the dose is from two to 10 mg per day.
With withdrawal symptoms, two to five tablets per day are indicated. In a hospital setting, injectable forms are prescribed.
When prescribing and using Phenazepam, you should clearly know that this medicine should not be taken for more than two weeks. The maximum period of regular intake in severe cases can reach two months. Cancel the drug gradually. In chronic conditions, the drug can be resumed after a three-week break.
Contraindications
"Phenazepam" both under the tongue and inside is prohibited under the following conditions and diseases:
- Shock conditions.
- Coma states of any nature.
- Angle-closure glaucoma.
- Severe chronic obstructive pulmonary disease.
- Myasthenia gravis.
- Severe depression.
- Acute alcohol or substance poisoning.
- First trimester pregnancy, breastfeeding.
- Children under 18.
- Individual sensitivity to the main or auxiliary components of the drug, including lactase deficiency.
Side effects
The nervous system of patients taking Phenazepam may react with drowsiness, increased fatigue, decreased concentration, dizziness, impaired gait and orientation, confusion, slow reaction, headache, mood swings, depressive manifestations, euphoria, trembling of the limbs, memory impairment, tic uncontrolled movements, decreased muscle strength, asthenia, double vision, impaired pronunciation of sounds, aggression, psychomotor overexcitation, suicidal tendencies, increased anxiety, sleep disturbance, hallucinations and addiction with withdrawal syndrome.
There may be a decrease in leukocytes, platelets and hemoglobin in the blood.
There are hypersensitivity reactions in the form of rash and itching when using the drug.
Sometimes the digestive tract gets disturbed. There is dryness of the oral mucosa or increased salivation, nausea, impaired stool and appetite, heartburn, increased liver enzymes in the blood with a deterioration in the functioning of this organ up to jaundice.
The kidneys and reproductive system respond with the following manifestations: incontinence or urinary retention, changes in sexual desire, menstrual disorders.
Drug Interactions
When appointedseveral medicinal substances, they must be taken separately, observing the time interval. You should definitely drink Phenazepam. Under the tongue or in the oral cavity, together with other medicines, this drug also does not dissolve.
- "Levodopa" when taken together will not work in full force.
- Zidovudine may become more toxic to the body.
- Other tranquilizers, sleeping pills, antiepileptic drugs, narcotic painkillers, centrally acting muscle relaxants and ethyl alcohol may mutually reinforce the action and side effects.
- MAO inhibitors increase toxicity.
- "Imipramine" increases its amount in the blood.
- Hypotension may occur if taken with blood pressure medications.
- "Clozapine" together with "Phenazepam" contributes to respiratory depression.
Medication form
The drug is available in 1 mg white tablets with a line in blisters of 10 and 25 pieces, as well as in jars of 50 pieces.
It should be remembered that Phenazepam tablets do not need to be taken under the tongue, they are swallowed and washed down with clean water.
