"Phenazepam" belongs to the category of highly active tranquilizers that have anticonvulsant, anxiolytic, and central muscle relaxant action. The positive principle of impact on the human body is significantly superior to all analogues. The drug can be used as a sleeping pill. The anxiolytic effect of the drug is expressed in a gradual decrease in emotional stress, weakening anxiety, fear and anxiety. To understand how much "Phenazepam" is excreted from the body, you need to study the composition and principle of action of the drug. This article will help with this.
Description
Phenazepam is a multifunctional benzodiazepine derivative. The tool belongs to the category of highly active tranquilizers. Bromdihydrochlorophenylbenzodiazepine is the active substance of the drug, only when used correctly it has an effect on the body.human positive impact. "Phenazepam" reduces the severity of tension, eliminates the excitation of the subcortical structures of the brain, and also inhibits polysynaptic spinal reflexes. The drug is often used as an anxiolytic, sedative hypnotic. The active substances have an anticonvulsant and muscle relaxant effect. Due to this, the patient's emotional stress is reduced, fear and anxiety disappear.
Composition and release form
Information on how much "Phenazepam" is excreted from the body is described in the instructions for the drug. Today, this medication is available in two dosage forms:
- Solution 0.1% for intramuscular, intravenous injection. One carton contains 10 ampoules.
- Pills. The package may contain 10, 25, 50 pills.
The instructions for use of Phenazepam tablets indicate that the main active ingredient is bromdihydrochlorophenylbenzodiazepine. Inactive ingredients: calcium stearate, lactose monohydrate, potato starch, croscarmellose sodium.
Injectable solution contains 1 mg of bromodihydrochlorophenylbenzodiazepine. Purified water, sodium hydroxide and hydrosulfite, distilled glycerin, polysorbate 80, povidone are used as auxiliary components.
Pharmacological principle of action
Each patient should know how much "Phenazepam" is excreted from the body in order to avoid negative side reactions. Thisthe drug belongs to the category of psychotropic drugs that suppress the central nervous system. Basic pharmacological effects of "Phenazepam":
- Sedative. The drug significantly reduces the severity of negative symptoms of neurotic origin.
- Anxiolytic. Perfectly eliminates emotional tension, fear, anxiety and a feeling of constant anxiety.
- Anticonvulsant. Prevents the spread of a convulsive impulse, but does not eliminate the excitatory focus.
- Sleeping pills. If the patient takes into account the fact how much Phenazepam is excreted from the body, then he will be able to significantly reduce the time to fall asleep, improving the quality of sleep.
- Central muscle relaxant. Reduces the intensity of the transmission of nerve impulses, due to which there is a gradual relaxation of smooth muscles.
The instructions for use of Phenazepam tablets indicate that the active ingredient of the drug quickly penetrates into the blood. The agent begins to act 30 minutes after ingestion. The maximum plasma concentration of the drug is reached 2 hours after ingestion. The elimination half-life varies from 6 to 18 hours. For those who want to know how long the Phenazepam injection works, it should be noted that a significant improvement in well-being occurs after 15 minutes. This form of medication is most often used to treat serious illnesses.
What does Phenazepam help with?
The drug is actively used in modernmedicine to combat various diseases of the nervous system, as well as chronic mental disorders. The drug is prescribed in the following cases:
- Insomnia and other sleep disorders.
- Separate forms of schizophrenia.
- Psychopathic and neurotic disorders, which are accompanied by severe fear, increased anxiety and anxiety, emotional lability.
- Nervous breakdowns.
- Disorders of the autonomic nervous system.
- Panic states.
- Epilepsy.
- Reactive psychosis.
- Alcohol withdrawal.
- Rigidity, hyperkinesis, tics.
To understand what Phenazepam helps with, you need to not only study the instructions, but also consult a doctor. Short courses of tranquilizers are prescribed to prevent acute emotional stress. Long-term therapy is essential to combat chronic mental illness.
Contraindications
The drug "Phenazepam" can be used only after prior consultation with a psychiatrist or neurologist. The patient must study the instructions for the medication. Main contraindications:
- Shock.
- Acute chronic obstructive pulmonary disease.
- Angle-closure glaucoma.
- Myasthenia gravis.
- Coma.
- Children under 18.
- Pregnancy and lactation.
- Acute respiratory failure.
- Individual sensitivity to the components of the drug.
- Acute depression.
- Renal and liver failure.
- Disorders of the brain.
- The patients are over 70 years old.
Instructions
Taking "Phenazepam" should correspond to the dosage recommended by the manufacturer. You can take 5 mg of the drug per day. This dosage should be divided into 2 doses. The maximum daily dose of the drug is 10 mg.
Treatment of the patient depends on the diagnosed disease:
- With pronounced agitation, anxiety and fear, therapy begins with a dosage of 3 mg per day. Gradually, the amount of the drug is increased in order to eventually achieve the desired therapeutic effect.
- For alcohol withdrawal, Phenazepam is taken at a dose of 2.5 to 6 mg per day.
- To combat epilepsy, the maximum concentration of the drug should not exceed 10 mg per day.
- For insomnia, the drug is used at a dose of 0.4 mg 35 minutes before bedtime.
- In psychopathic and neurotic conditions, the initial dose of the drug is 1 mg. After 4 days, the concentration of the substance can be increased to 5 mg per day.
- Whenpathologies with increased muscle tone, the drug is used 3 mg 2 times a day.
To understand how long you can take Phenazepam, you need to consider that the standard therapeutic course is 14 days. In some cases, the duration of treatment can be increased up to two months. At the final stage, the dosage of the medication is reduced gradually.
Adverse reactions
If the patient figured out how long the Phenazepam pill lasts, then this will help to avoid the most common mistakes. High activity of the active substance can provoke the development of ataxia (impaired coordination of movement), dizziness, drowsiness.
Main side effects:
- Constipation.
- Medication addiction.
- Decrease in blood pressure.
- Development of drug dependence.
- Decreased sex drive.
- Allergic reactions.
- Disordered concentration.
If the patient began to notice a deterioration in the general state of he alth, then you need to stop taking the medication and seek medical advice.
The effect of the drug on the emotional state of a person
There are many indications for the use of Phenazepam tablets, but patients must be aware that the drug has a strong effect on the central nervous system. In some cases, this is fraughtthe following symptoms:
- Increased aggressiveness.
- Euphoria.
- Pitches of rage.
- Depression.
At the initial stage of treatment, the patient may experience high spirits, but longer therapy is fraught with a significant deterioration in mood, nervousness, and aggressiveness. In some cases, there is a strong excitement, as well as an attack of psychosis. If these symptoms appear, you must stop taking Phenazepam.
The consequences of an overdose
With long-term use of "Phenazepam" side effects are very difficult to avoid. If the patient exceeds the allowable dosage, then this is fraught with severe intoxication of the body. In such a situation, a person experiences a depressed consciousness, respiratory and heart failure. Significantly increases the risk of coma, death.
Basic overdose symptoms:
- Trembling of limbs (tremor).
- Increased sleepiness.
- Lower blood pressure.
- Weakened motor reflexes.
- Depressed heartbeat.
- Disorientation, confusion.
- Involuntary rapid pupillary movements (nystagmus).
- Weakened motor reflexes.
- Difficulty breathing, shortness of breath.
If at least one symptom of intoxication occurs, a classicgastric lavage, take a high-quality sorbent, and also seek help from the hospital. Only a doctor can prescribe drugs that support the functions of the respiratory and cardiac systems. Phenazepam antidotes - Anexat, Flumazenil.
A good effect can give laxatives that do a good job of removing all toxins from the body. In a hospital, infusion therapy is necessarily carried out, which involves the introduction of a Ringer solution, glucose. The patient must drink at least 2 liters of non-carbonated water per day. If there is a threat of impaired respiratory or cardiac activity, then the patient is prescribed an effective antidote. The active substance is administered intravenously.
Pregnancy and lactation
The active substance "Phenazepam" has a toxic effect on the developing fetus, which increases the risk of congenital malformations when using the drug in the first trimester. The use of standard therapeutic doses in later pregnancy may cause depression of the central nervous system of the newborn child. Long-term use of "Phenazepam" can provoke the development of a withdrawal syndrome in a baby. The use of the drug before childbirth can cause respiratory depression, hypotension, decreased muscle tone, hypothermia, and a weakening of the sucking act in the baby.
Available analogues
Numerous side effects with long-term use of "Phenazepam" make patients chooseother medicinal products. The following drugs are in demand analogues of the drug:
- "Phenorelaxan".
- Fezipam.
- Fenzitat.
- Fezaneth.
- Elzepam.
- Tranquezipam.
"Phenazepam" belongs to the category of potent tranquilizers of the benzodiazepine group, which have a pronounced sedative, hypnotic, anxiolytic effect. Due to the specific effect of the drug on the nervous system, a high degree of effectiveness is achieved in the treatment of many neurological and psychopathic pathologies, insomnia. The drug has a huge list of contraindications, which can cause serious adverse reactions. Prolonged use is fraught with addiction and drug dependence.
That is why the sale of the drug from pharmacies without a prescription is strictly prohibited. "Phenazepam" can be taken only as prescribed by a doctor, observing the dosage. Otherwise, the patient may face unpredictable consequences that will negatively affect the work of the whole organism.
Principle of interaction with other medicines
Simultaneous use of "Phenazepam" with drugs from other groups is fraught with the fact that the active substance may enter into a chemical reaction. This entails a change in the effectiveness of drugs, aggravation of common adverse reactions.
Interaction of "Phenazepam"with other drugs:
- The effectiveness of Levodopa is decreasing.
- The inhibitory effect on the respiratory system of Clozapine is increasing. This situation is fraught with a complete cessation of breathing.
- The toxic effects of "Zidovudine" (a common antiviral agent that is actively used in the complex treatment of HIV) are significantly increasing. "Phenazepam" is not recommended to be combined with MAO inhibitors, as well as "Imipramine".
- The effect of antihypertensive drugs is increasing.
- The therapeutic efficacy of antiepileptic drugs, sleeping pills, muscle relaxants, and narcotic analgesics is increasing.
Application features
"Phenazepam" has a persistent and pronounced ability to cause drug dependence in a patient with prolonged use in large doses. Those people who abuse the drug suffer from frequent hallucinations, panic attacks, obsessive thoughts, and sleep disorders. Manufacturers of the drug note that Phenazepam is prescribed with extreme caution for severe depression, as this remedy can be used to implement suicidal plans.
The drug is forbidden to use by drivers, as well as those people who service mechanisms that require accurate and quick reactions. The combination of "Phenazepam" with alcoholic beverages is fraught with a significant decrease in the effectiveness of the drug, an increase in its toxic effects, as well as the development of overdose symptoms. The active substances of the drug inhibitbreathing and heart activity.
Numerous patient reviews of "Phenazepam" indicate that addiction to the drug develops very quickly. Because of this, it becomes increasingly difficult for a person to do without the drug. In the intervals between taking the pills, all negative emotions are significantly aggravated, the situation is saved only by another pill of a powerful tranquilizer.
