Pain is a protective reaction of the body and a signal to a person that inside, most likely, something went wrong. But sometimes it is unbearable to endure it, and besides, it is often not necessary. There are many modern drugs that allow you to quickly stop pain attacks. One of them is "Ibuprofen" (400 mg), the instructions for use of which recommend taking it to relieve discomfort in a variety of diseases.
General information
There is a large class of drugs that are non-steroidal anti-inflammatory drugs. They eliminate pain and have an antipyretic effect. Also, these drugs reduce the severity of the inflammatory process, and the effect of them is quite fast. One of these drugs is Ibuprofen (400 mg). Instructions for use recommend taking it for pain of various nature and elevated body temperature.
Remedy refers to fast-acting drugs that relieve symptoms, but, unfortunately, do not eliminatecauses of the disease. Therefore, most often "Ibuprofen" is part of the complex therapy of various diseases. It allows a person to endure the recovery process much easier due to the fact that the clinical picture becomes less pronounced against the background of its intake. In parallel with it, etiotropic treatment is prescribed, that is, one that affects the true nature of the disease.
Forms and composition
The first thing that catches your eye when you open the package of the drug "Ibuprofen" (400 mg) - instructions for use. The composition of the drug is as follows:
- active ingredient - ibuprofen;
- additional components (may differ depending on the manufacturer) - silicon dioxide, corn starch, magnesium stearate, titanium dioxide, talc, sodium carboxymethyl starch, povidone K30, macrogol 4000, hypromellose, microcrystalline cellulose.
Each tablet has a special feature that makes it possible to divide the medication into 2 equal halves. This is very convenient in cases where you need to take, say, 200 or 600 mg of ibuprofen at the same time.
Non-steroidal anti-inflammatory drugs with prolonged use, unfortunately, adversely affect the mucous membrane of the digestive system, this also applies to the drug "Ibuprofen". Instructions for use of the tablet (400 mg) recommend taking it after meals so that the stomach does not succumb to the irritating effect of the drug.
Mechanismdrug action
During inflammation, prostaglandins (physiologically active substances) are actively formed in the tissues, an increased level of which brings pain to a person. The reaction of their synthesis is accelerated by the enzymes cyclooxygenases of the 1st and 2nd type (COX-1 and COX-2).
Non-steroidal anti-inflammatory drugs inhibit the formation of these catalysts, and the amount of prostaglandins rapidly decreases, because the reaction is not so intense. Ibuprofen (400 mg) also has this mechanism of action. Instructions for use, description of the drug in pharmaceutical reference books indicate that the remedy effectively eliminates pain, relieves inflammation and lowers the overall body temperature. The maximum concentration of the active substance is observed 1-2 hours after taking the tablet inside. The drug is excreted from the body mainly with urine, and accumulates in the body in plasma and periarticular fluid.
The advantage of tablets over other dosage forms
"Ibuprofen" is available in different doses and dosage forms. It is presented in syrups, tablets, suspensions and capsules. But if we consider "Ibuprofen" (400 mg), the instructions for use of which involve oral administration, then in this dosage it is available only in tablets. This type of medicine has certain advantages:
- convenience of reception;
- no unpleasant aftertaste of the active substance due to the shell and additional components;
- lasting effect;
- exact dosage.
The use of tablets does not require the participation of medical personnel (as in the case of injections, for example) and compliance with sterility conditions. Ibuprofen tablets are medium in size and easy to swallow with a little water.
Indications for use
The most comprehensive document that describes the indications for the use of the drug "Ibuprofen" - instructions for use. Tablets (400mg) are usually given to the patient for the following symptoms and conditions:
- migraine;
- painful periods;
- inflammation and pinched nerves;
- high body temperature;
- toothache;
- stiffness and discomfort in the joints with arthritis, arthrosis and non-rheumatic inflammation;
- muscle pain;
- inflammation of the ligaments;
- rheumatoid processes;
- inflammation of the uterine appendages;
- Ankylosing spondylitis;
- manifestations of SARS, tonsillitis, bronchitis.
The drug can be used as part of complex therapy in patients with nephrotic syndrome. It reduces the amount of protein in the urine and reduces the intensity of pain. The drug helps to reduce discomfort in the postoperative period, although it cannot act as the only analgesic in this case.
"Ibuprofen" (400 mg): instructions for use, analogues of the drug
Pills with this dosage are available under the following trade names:
- "MIG-400".
- Nurofen Forte.
- Faspic.
- Brufen.
- "Burana".
- Ibuprom Max.
- Ibuprofen Nycomed.
There is also a quality medicine of domestic production "Ibuprofen Hemofarm" (400 mg). Instructions for use assumes its use according to the following scheme:
- for moderate pain - 1 tablet 3 times a day;
- with rheumatoid inflammation of the joints - 2 tablets three times a day;
- for muscle pain and diseases of the ligaments - 1.5 tablets 2-3 times a day;
- with Bechterew's disease - 1-1, 5 tablets up to 4 times a day.
These recommendations are standard for taking ibuprofen 400mg tablets from any manufacturer. To reduce the temperature, the amount of the drug is calculated based on the weight of the patient. If the mark on the thermometer has reached 39, 2, you need to drink a remedy from a ratio of 10 mg / kg of a person’s weight (if the value is less, then 5 mg / kg of the patient’s body weight is enough).
Contraindications
Not all people can safely use Ibuprofen tablets (400 mg). Instructions for use of contraindications indicate the following:
- digestive ulcers;
- gastritis and chronic intestinal inflammation during periods of exacerbation;
- bronchial asthma;
- severe liver dysfunction (such as cirrhosis or deep damage to the blood vessels of this organ);
- under 12;
- last trimesterpregnancy;
- high blood pressure;
- edema;
- diseases of the ophthalmic nerves;
- color perception disorders due to ophthalmic diseases;
- individual intolerance to drug components;
- heart failure;
- poor blood clotting.
During lactation, ibuprofen passes into breast milk, but in very low doses. Cancellation of natural feeding of a newborn due to the appointment of this drug to the mother is necessary only in cases where the woman will have long-term drug therapy.
What is the danger of an overdose
Before treatment, it is desirable to find out such information about the Ibuprofen (400 mg): instructions for use, release form and contraindications. But it is important to read about the safe doses of the drug, because their excess can lead to sad consequences. Between doses, it is important to maintain a minimum interval of 6 hours; you should not drink these pills more often because of the high risk of side effects on the body. The daily dose of the drug in any case should not exceed 2.4 g.
Symptoms of taking too much medication:
- nausea (sometimes vomiting is possible);
- headache;
- impaired visual clarity;
- lower blood pressure;
- abdominal pain;
- dizziness;
- shortness of breath;
- blue skin.
There is no specific counteracting agent, therefore, if alarming symptoms occur, the patient needs torinse the stomach, provide fresh air and call an ambulance immediately.
Compatibility with other drugs
Not all medicines are compatible. They can enhance the side effects of each other or weaken their effectiveness. No exception in this respect and the drug "Ibuprofen" (400 mg). Instructions for use warns that the medicine should not be taken with such medicines:
- drugs to treat hypertension (it reduces their activity and can cause high blood pressure);
- Furosemide and similar diuretics (ibuprofen makes them difficult);
- Antineoplastic drugs (because ibuprofen enhances their toxic effects on the body).
Alcohol should not be consumed during treatment with the drug, as this combination leads to an undesirable side effect of Ibuprofen and enhances the harmful effects of alcoholic beverages.
Reviews of doctors
Doctors say that ibuprofen is one of the safest representatives of non-steroidal anti-inflammatory drugs. On its basis, a huge number of over-the-counter drugs with high efficiency are produced. Doctors noticed that those patients who took into account all contraindications and did not exceed the recommended dosage only benefited from taking the medicine.
Reviews of experts say that the medicine allows you to quickly relieve pain in neurological and orthopedicdiseases. And although it does not remove the cause of their appearance, it still greatly facilitates the patient's condition. When pain subsides, a person’s mood rises and he calms down, and, according to doctors, the outcome of treatment depends half on psychological comfort.
Patient testimonials
Patients who have taken this drug are generally satisfied with its speed of action and relatively low price. Tablets well stop attacks of headache and joint pain, effectively relieve fever. Many arthritis sufferers have noticed that after taking a pill in the morning, they could move without pain until at least lunchtime.
Patients with acute diseases of the upper respiratory tract (most often it was a sore throat) were satisfied with the analgesic effect of Ibuprofen. Thanks to these pills, they could swallow food and drink liquids without terrible discomfort and pain. True, to maintain a lasting effect, they had to take the drug 2-3 times a day.
The opinions of those people who often suffer from headaches are divided. Some of them say that the medicine quickly and permanently eliminates pain and for this it is enough to take 0.5-1 tablet. But patients with severe migraines who have previously taken prescription drugs say the effect isn't always as strong as it should be.
"Ibuprofen" (400 mg): instructions for use, description of the expiration date and storage conditions
One of the benefits of tablets is their long shelf life, whether opened or sealed. This is also true for the drug "Ibuprofen" (400 mg). Instructions for useprovides for a shelf life of the drug up to 3 years at room temperature in a dry place. The medicine must be kept out of the reach of children to prevent them from accidentally swallowing the tablets.
Ibuprofen tablets are normally one shade and have smooth edges. If any of them differ in color from the one that was originally when the package was opened, the drug should not be used. It could oxidize or deteriorate, so its use is unlikely to be of any use, but the chance of an unpleasant effect on the body is very high. It is undesirable to store the medicine in the kitchen or in the bathroom (due to high humidity and temperature).
Pediatric Use
The first thing you need to pay attention to before using Ibuprofen (400 mg) in childhood is instructions for use. The dosage for a child is significantly different from that recommended for adults. Up to 12 years, the drug is not used in principle, since there are special "children's" forms of drugs with ibuprofen (candles, suspensions, syrups).
On average, a child may be recommended to take the drug at 100-300 mg 3 times a day. The permissible maximum daily dose for children is 1 g. The frequency of administration should always be determined by a physician who is aware of the diagnosis and condition of the child. In children, this drug is most often prescribed to treat teenage arthritis, rheumatism, and to lower body temperature.
Is it possible to use the medicine during pregnancy
FromFor ethical reasons, most drugs are never tested in clinical trials (that is, human trials) while a woman is pregnant. Therefore, data on theoretical harm or its absence are either completely empirical or based on the results of experiments with animals. It is still not known exactly how a drug such as Ibuprofen (400 mg) can affect a pregnant woman. The instructions for use indicate the data, according to which, it definitely should not be used in the last 3 months of pregnancy.
But even in the initial stages of gestation, the ratio of risk and benefit of the remedy should be decided by the woman's attending physician. Considering that during this period, the laying and development of all the organs of the unborn baby takes place, it is not necessary to use this remedy without special indications.
Additional recommendations
It is undesirable to take the drug for more than 4 days in a row. If the symptoms worsen or do not subside, it is necessary to seek the advice of a doctor to correct the prescribed therapy. In general, the drug is well tolerated, but for older people it is better to start treatment with Ibuprofen in minimal dosages, reducing the overall duration of the course.
When in pain, many people do not go to the doctor, but start looking for treatment options on their own. Now there are quite a lot of effective drugs in the pharmacy, which are well known to everyone, among them is the medicine "Ibuprofen" (400 mg). Instructions for use, reviews - these are information that you can easily find on your own or find out throughacquaintances, but self-medication is extremely dangerous. It is much better to consult a doctor to be sure that the drug can be taken by a person, and he has no (sometimes not always obvious) contraindications.
