The human immunodeficiency virus is today the most dangerous and deadly for him. Physicians and scientists around the world are concerned about the creation of a cure for this disease. And if a vaccine against HIV and AIDS were invented, it could save tens of millions of lives. However, work is underway on this, and in the future this medication can be invented. A completely different question: when will this happen?
Forecasts for the future
Not so long ago, the biomedical center of St. Petersburg worked on the creation of this drug, developing various options. The professor of this center, who is the head of the entire work process, said that in the future, the HIV vaccine could be published in about five to six years. Regarding the development of the center itself, the first phase of testing their medicine began four years ago - in the fall of 2010. And these experiments were recognized as successful! However, the second phase started only this summer. Only this year we managed to get everythingnecessary permissions and funds.
Clinical trials
What are they for and how do they work? In fact, everything is clear here. After all, this stage is necessary in order to find out exactly how this vaccine acts on the human body. The study is under the strictest control, only an experimental vaccine is administered to volunteers. Before testing the drug on humans, it was tested on animals - this stage showed the immunogenicity of the drug and its safety. And of course, the state expertise gave 100% confirmation that this drug can be included in clinical trials.
First stage
It should be recalled how the first stage went. It was attended by people who do not have the immunodeficiency virus. There were 21 of them, including both women and men. They were divided into three groups, each of which had its own specific dose of medication (0, 25, 0, 5 and 1 milligram each). As a result of the tests, it was found that this vaccine is absolutely harmless to he alth. This was the main goal of the first phase. Several other conclusions were also made. Firstly, it was possible to find out that drug addicts are infected with only one particle of the virus. Secondly, some people who regularly have intimate contact with those who have the immunodeficiency virus do not get sick. The organism of these personalities seemed to block the disease. Here, scientists had several assumptions - they could have previously met with the virus that is similar to HIV,and thus developed immunity directly to immunodeficiency disease. And, finally, the third - it was possible to prove that HIV in the blood can be caught even on the first day of infection. And if you immediately start giving the infected special medicines, then the disease will be avoided.
Second stage
60 volunteers will take part in the next stage, and all of them are infected, only with the subtype virus. In fact, the HIV vaccine developed by the medical center is aimed at combating this disease. Again, the participants will be divided into three groups, the first two will receive the drug at 0.25 mg and 0.5 mg, but the third will apply the placebo effect. That is, vaccination with saline. Who will be in which group is unknown. But the conditions are very tough. The completion of the HIV vaccine trial is scheduled for the end of next year, 2015, and the results will be summed up at the same time.
Features of the drug
The HIV vaccine under development belongs to the fifth group on the danger scale. In a word, it is completely safe and non-toxic. There is no infectious agent in this preparation, therefore the used ampoules are eliminated in the usual way. And the fact that this HIV vaccine is safe was confirmed at the very first stage of the trial. Actually about the name, this drug is designated as “DNA-4”. The drug contains four special viral genes, I must say, this is enough to cover all parts of the genome. However, the scientists of the center are already in full swingdeveloping another drug, DNA-5. But it is still too early to say what the new HIV vaccine will turn out to be, as trials of the previous drug have not yet been completed.
How to deal with the virus
To cope with this disease, you need to make a lot of effort. After all, only by strengthening your immunity, you can slow down the destructive effect of the virus. Today, there are a lot of modern drugs and drugs that have virtually no side effects. Their main disadvantage is that a person is forced to take these medications for life. Otherwise, if you stop using them, the virus will go on the offensive. And they are also very expensive. How to deal with HIV? First, you need to undergo antiviral therapy. Secondly, the HIV vaccine, but it is currently only at the development stage. Thirdly, the rejection of all bad habits, which include the use of alcohol, drugs, casual intimate contacts, etc. In fact, all of the above is a combined prevention. And she really helps.
Drug action
One more Russian invention should be noted, but first we need to clarify something. Medicines for this disease have been created for a long time. They help, but not as effectively as they should. And the thing is that existing medicines are not able to cope with the main property of AIDS - that it can mutate. However, the new drug proved to be effective even after three viral mutations. The AIDS vaccine preventsreplication of the virus in the body. It acts in such a way that it reduces its concentration to those values that are even less than the normative ones. This AIDS vaccine is the result of a global effort that began six years ago, in 2008. And optimistic forecasts of experts assure that this miraculous remedy may become the main drug that will help cure a terrible disease. Many pharmaceutical companies are already interested in investing in the further development of this drug. Indeed, this is what society needs. After all, since the beginning of the HIV epidemic (that is, since the beginning of the 80s), almost 60 million people have been infected with this virus and 25 million of them have already died.
Testing and research
Some patients managed to experience the miraculous effects of this drug. In any case, people who ventured to find out what the new HIV vaccine is spoke enthusiastically about this drug. Probably, the drug is really effective - it was not without reason that highly qualified specialists from several companies and research centers worked on its creation. In fact, this is a revolution in medicine, since this remedy is based on nanotechnology. Lev Rasnetsov, who is the inventor of this tool, hopes that this HIV vaccine will be an innovation. This medicine was produced on the basis of molecular compounds that are allotropic forms of carbon (which include graphite, carbyne and diamond). This medicine blocks the affectedbody cells, slowly killing them. With the help of this drug, you can maintain normal he alth. However, there is still one minus, and it was mentioned a little higher - you need to use the drug for life.
