Many obstetrician-gynecologists during their work had to answer questions from patients about which drug is better - Duphaston or Utrozhestan.
But it is simply impossible to definitely lean in favor of one or another option, because each of them has its drawbacks.
To understand what is the difference between these medicines, first you need to understand when they are used, what they are for. Both drugs are prescribed to correct the level of progesterone in the body in cases of menstrual irregularities, pronounced PMS, endometriosis, threatened miscarriage or infertility, which arose due to the insufficiency of the second phase of the cycle, etc.
When choosing which remedy to prescribe - "Dufaston" or "Utrozhestan", doctors are guided by the number of side effects and the convenience of the method of taking each of them. Patients, having often read information that the latter option, unlike the first, is natural progesterone, which is extracted from plant materials, tend to favor it. But this formulation is not entirely correct. Tablets"Duphaston" is called synthetic progesterone due to the fact that the chemical structure of this substance differs by one methyl group from the formula of the natural hormone, but this does not affect its properties. It is also worth noting that both drugs are obtained from plant materials belonging to the Dioscorea family.
When choosing Dufaston or Utrozhestan, it must be borne in mind that when taking the latter, drowsiness, fatigue, dizziness often occur, some even experience allergic reactions. Intermittent bleeding from the uterus and altered cycle times may occur with both drugs. Both drugs are quite successfully used during pregnancy, when a woman has progesterone deficiency. In addition, do not be afraid if the doctor chooses which drug to prescribe for you - "Dufaston" or "Utrozhestan", no one prescribes them without special need. Perhaps you have a lack of progesterone, which is confirmed by tests, a threatened miscarriage or a history of aborted in the early stages of pregnancy.
True, with severe toxicosis, which is accompanied by vomiting, it is recommended to use Utrozhestan capsules. The description given in the instructions says that during the first trimester it is better to take it not orally, but intravaginally. This allows you to save the maximum amount of progesterone in the body. Also, this drug is prescribed if a remedy with an antiandrogenic drug is required.effect. In addition, when taken orally, it helps to reduce the amount of estrogen. But Duphaston tablets (for pregnant women they are recommended very often) do not affect anything except progesterone. These moments often become decisive when choosing the drug to be prescribed.
Also everyone needs to know that although the described drugs are hormonal, they do not suppress ovulation and cannot be used as contraceptives.
