Have a glass of wine on Friday or a martini at the club with friends on Saturday? The usual thing. But even in such minimal doses, alcohol may not be compatible with the medications you are taking.
"Inderal" - what is it?
"Anaprilin" (propranolol hydrochloride) is a β-adrenergic blocker, a drug for the cardiovascular system, which has a hypotensive, antiarrhythmic, antianginal effect. Inhibits lipolysis of adipose tissue, preventing an increase in the level of fatty acids in the blood. The bioavailability of propranolol is 26%.
It is prescribed for cardiomyopathy, atrial and sinus tachycardia, coronary artery disease, high blood pressure, angina pectoris, etc. Anaprilin improves peripheral vascular resistance and normalizes blood pressure.
Contraindications
"Inderal" is contraindicated in patients with bronchial asthma, with heart failure. The drug is not prescribedpregnant and lactating women. It has a whole list of side effects: convulsions, nausea, vomiting, ischemic colitis, heart failure, dizziness, insomnia or drowsiness, depression, hallucinations, circulatory disorders, diarrhea or constipation, cough, shortness of breath, exacerbation of chronic psoriasis, decreased libido and potency, etc. e.
Interaction with other drugs
If some other drug is taken along with Anaprilin, this must be reported to the attending physician. The hypotensive effect of Anaprilin may increase with the simultaneous use of sympatholytics, hypotensives, hydralazine, anesthetics, etc. The hypotensive effect of Anaprilin may decrease when taken simultaneously with non-steroidal anti-inflammatory drugs, estrogens, glucocorticoids (steroid hormones). Thus, you should not take Anaprilin before or after visiting the dentist if you plan to take non-steroidal anti-inflammatory painkillers, such as nimesulide.
"Inderal" is able to slow down the excretion of lidocaine and aminophylline, increasing their concentration in the blood plasma, prolongs the action of non-depolarizing muscle relaxants. The joint administration of radiopaque substances increases the risk of anaphylactic shock, so it is better not to take Anaprilin before an MRI, CT using contrast. In general, before agreeing to the use of radiopaque agents, it is best to tell the doctor about the medicationstaken in the last 12-24 hours.
The simultaneous use of Anaprilin and allergens for immunotherapy or skin tests dramatically increases the risk of a severe systemic allergic reaction.
"Inderal" can mask the manifestation of tachycardia in patients with diabetes mellitus who take insulin or any drugs that lower glucose levels.
If an operation with anesthesia is scheduled, you should stop taking Anaprilin a few days before it or tell the doctor and ask him to choose an anesthesia with the least inotropic effect.
Interaction with alcoholic beverages
Is it possible to "Anaprilin" with alcohol? To immediately dot all the "i", the answer is no. Anaprilin and alcohol are incompatible.
Despite all the advantages, the drug has a wide range of contraindications and special conditions for taking. The instructions indicate that it is not recommended to take ethanol and alcohol-containing drinks for the entire time of taking Anaprilin.
Simultaneous intake of Anaprilin and alcohol can lead to a critical decrease in blood pressure, which, in turn, will cause orthostatic collapse and death.
Orthostatic collapse is accompanied by an insufficient supply of blood, and therefore oxygen, to the brain as a result of excessive pressure reduction.
"Inderal" should not be mixed with substances that affect the functioning of the cardiovascular system, includingand with alcohol-containing drinks, as well as with tranquilizers and antipsychotics.
Alcohol, getting into the blood plasma, promotes the connection of red blood cells, which in certain cases leads to the formation of blood clots.
Blood saturated with alcohol toxins reaches the heart. These toxins destroy the organ, forming scars, as a result of which the heart muscle ceases to be elastic and wears out. The heart does not have time to pump blood and “chokes” it. Hence the violation of the rhythm and other diseases.
With prolonged use, Anaprilin exhibits hepatotoxicity. This is a property of almost all drugs, so combinations of medicines should be selected only by a doctor. The liver is already destroyed by alcohol, so it should not be finished off with Anaprilin along with alcohol-containing drinks.
What does Anaprilin do with alcohol?
"Inderal" enhances the effects of alcohol on the body. Therefore, even if a person drinks just a little, he may show all the signs of severe alcohol intoxication:
- dizziness;
- confusion;
- discoordination;
- memory loss.
Therefore, Anaprilin and alcohol, with which there is no compatibility, cannot be taken. Alcohol enhances the absorption of the drug, which can lead to an overdose. The latter is dangerous because the pressure can drop too sharply. Hypotension may be so significant that urgenthospitalization.
Alcohol after Anaprilin
Even if you were not prescribed Anaprilin as a course, but you drank one pill, you need to refrain from drinking alcohol for 5 hours after taking it. This time will be enough for the active substance to be absorbed into the blood. The half-life of "Anaprilin" after a single dose is usually 3-5 hours. When taking Anaprilin in a course, this time increases to 12 hours. Therefore, if you are taking Anaprilin as a course, you should abstain from alcohol for at least 12 hours after taking the pill.
This does not apply to people with diseased kidneys and liver. Up to 90% of propranolol is excreted by the kidneys. The liver takes an active part in the neutralization of alcoholic poisons. If these organs do not work properly, the excretion of substances slows down. If you have diseases of these organs, it is best not to drink alcohol for 24 hours after drinking.
If Anaprilin was taken with alcohol, the following signs can be observed:
- nausea;
- vomit;
- rapid breathing;
- vasospasms;
- large pressure drop;
- loss of consciousness;
- collapse;
- sometimes death comes.
"Inderal" and alcohol greatly enhance each other's action. A small amount taken can be a lethal dose.
After alcohol
Ethyl alcohol in the body is broken down intofine particles, and one such particle is acetaldehyde. It is a strong poison that severely damages internal organs. With the accumulation of acetaldehyde in the body, poisoning occurs. That is why a person feels bad, his hands are trembling, his heartbeat quickens.
"Inderal" can be taken after alcohol. Moreover, it is recommended by doctors for severe hangovers. To eliminate the symptoms of poisoning and to stabilize blood circulation, you can drink Anaprilin. But to decide whether "Anaprilin" in this case is right for you, only a doctor should decide. A simple layman does not understand what kind of reaction substances enter into in his body, and he cannot judge the consequences. If the body has not yet removed the remnants of ethyl alcohol, then perhaps the doctor will prohibit taking Anaprilin.
Possible consequences
The combined use of "Inderal" with alcohol can cause toxic damage to the heart muscle, and blocking signal transmission from the atrium to the ventricle can generally lead to cardiac arrest. Ethyl alcohol strongly depresses the activity of the nervous system and heart. Simultaneous reception of "Inderal" and alcohol, or failure to observe sufficient time between doses, can lead to:
- hypoglycemia, because the composition increases the fall in blood sugar;
- fall in blood pressure;
- spasm of peripheral vessels with the appearance of cold in the extremities;
- nauseous;
- weakness and even fainting.
"Inderal" and alcohol. Reviews
If we analyze consumer feedback, the picture is very ambiguous. Some patients taking "Anaprilin" indicate that the joint intake with alcohol leads to the normalization of blood pressure and to good he alth. However, another part of the patients speaks extremely negatively about this combination and talk about a deterioration in their general state of he alth, about disturbances in the work of the heart, about the development of a depressed, depressive state. Reviews of some patients or their relatives indicate that the joint use of Anaprilin and alcohol often ends in death.
