The drug "Ferrum Lek" is used to treat anemia and iron deficiency in adults and children, including infants, and, in addition, during pregnancy and lactation. It is an antianemic agent in which iron is contained in the form of a complex compound of polym altose hydroxide.
Medication description
For Ferrum Lek ampoules, the instructions for use indicate that the molecular weight of this complex is quite large, and its diffusion passing through the mucous membrane of the gastrointestinal system is forty times slower compared to ferrous iron. The complex is stable without releasing iron ions under physiological conditions. The active element of the multinuclear zones of the system is included in a structure that is similar to the natural iron compound, the so-called ferritin. Due to the presence of this similarity, the main element of the presented complex can only be absorbed through active absorption.
Iron-binding proteins, which are located on the surface of the intestinal epithelium, completely absorb iron through targeted competitive ligand exchange. The absorbed type of substance is deposited mainly in the liver, where further binding with ferritin occurs. Later, in the bone marrow, it becomes part of hemoglobin. The polym altose hydroxide complex does not have the pro-oxidant properties that are typical of iron layers. Thus, the main active ingredient in this preparation is polym altose hydroxide along with excipients. This confirms the instructions for use for Ferrum Lek ampoules.
This preparation contains iron in the form of a complex compound of polyisom altose hydroxide. Such a macromolecular type complex does not provoke the release of iron in the form of free ions. The product is similar in its structural structure to the natural compound of the element, namely ferritin. This hydroxide is not characterized by the pro-oxidant characteristics that are inherent in many s alts of this trace element.
This is also confirmed to the "Ferrum Lek" in ampoules instructions for use and reviews.
Iron, which is included in the composition, is able to quickly compensate for the lack of the corresponding element in the human body, including against the background of pronounced iron deficiency anemia, thus restoring the level of hemoglobin necessary for normal life.
Whenthe use of the drug is a gradual process of regression of the clinical symptoms of iron deficiency, such as fatigue, weakness and dizziness along with tachycardia and soreness, as well as dry skin.
Pharmacokinetics of the drug
As the instructions for use indicate to Ferrum Lek ampoules, iron absorption, which is measured by the level of hemoglobin in erythrocytes, is inversely proportional to the dose taken, that is, the higher the amount, the lower the corresponding process. There is a statistically negative correlation between the level of deficiency of a given substance and its presence, since the greater the lack of iron, the better absorption occurs. To the greatest extent, the substance is absorbed in the duodenum, as well as the jejunum. The remaining amount of the microelement is excreted with feces. Its excretion, along with the separating cells of the epithelium of the gastrointestinal system and skin, as well as together with sweat, urine and bile, is approximately equal to one milligram of iron per day. In the female body during the menstrual cycles, an additional loss of an important trace element occurs, which, of course, must be taken into account. Analogues "Ferrum Lek" in ampoules will be presented below.
It should be noted that immediately after intramuscular injection of the drug, it enters the bloodstream very quickly. So, fifteen percent of the dose hits after fifteen minutes.
Indications for use of Ferrum Lek
For ampoules "Ferrum Lek" instructions foruse indicates that the drug is prescribed in the following cases:
- latent iron deficiency therapy;
- treatment of anemia due to iron deficiency;
- prevention of deficiency of this trace element during pregnancy;
- situations in which treatment with oral iron preparations is ineffective or not feasible, for example, for an injectable form.
Final form "Ferrum Lek" in ampoules
The drug in the form of a solution can be administered exclusively by intramuscular route. In no case should intravenous administration of the drug be allowed. This confirms the instructions for Ferrum Lek ampoules.
Before using the first therapeutic dose, a person should enter a test amount of the product, which will be equal to half the contents of one ampoule, which is twenty-five to fifty milligrams of a trace element. Provided that there are no adverse reactions from the body, the remainder of the initial daily dose is added within fifteen minutes after administration.
The dosage of "Ferrum Lek" in ampoules is selected individually, depending on the general iron deficiency. Against the background of a known amount of lost blood, intramuscular injection of two ampoules leads to an increase in hemoglobin level, which will be equal to the equivalent of one blood unit.
Adults and the elderly are prescribed one hundred to two hundred milligrams, that is, from one to two ampoules, depending on their level of hemoglobin in the blood. The maximum daily dose for children is expressed as seven milligrams perkilogram of the child's weight.
Rules of drug administration
The drug "Ferrum Lek" in ampoules must be injected deep intramuscularly alternately into the left and right buttocks. In order to reduce pain, as well as avoid staining the skin, it is advisable to follow the rules below:
- the product is injected into the upper outer region of the buttocks, using a needle five to six centimeters long;
- before the injection process, after disinfection of the skin, it is necessary to move the subcutaneous tissues to the lower part by two centimeters in order to prevent possible leakage of the agent;
- immediately after the injection of the substance, the subcutaneous tissues must be released, and directly the injection site, pressing, hold in this position for one minute;
- before using a solution intended for intramuscular injection, it is important to carefully examine the ampoules, only those that contain a homogeneous solution without any sediment should be used;
- solution for intramuscular injection is always administered immediately after opening the vessel.
Possible side effects
As the instruction indicates to the Ferrum Lek remedy in ampoules, as a result of the body receiving an excess content of a substance in general well-being, a feeling of heaviness or overflow may occur, and, in addition, pressure in the epigastric region. Quite often, in such situations, nausea, constipation and diarrhea appear, while staining of feces in darkcolor - the phenomenon of black stools, which is explained by the excretion of the non-absorbed part of the iron and is not characterized by clinical significance.
We emphasize once again that Ferrum Lek is not used intravenously in ampoules.
Contraindications
Ferrum Lek is contraindicated for:
- excessive iron in the body, for example, against the background of hemochromatosis;
- with violations of iron utilization processes, in this case we are talking about anemia, which is caused by lead intoxication or the sideroachrestic nature of this pathology;
- for anemia that is not associated with iron deficiency, such as hemolytic and megaloblastic, caused by cyanocobalamin deficiency;
- with Osler-Rendu-Weber syndrome;
- against the background of infectious diseases of the kidneys occurring in acute stages;
- in case of uncontrolled hyperparathyroidism;
- presence of decompensated liver cirrhosis;
- for infectious hepatitis;
- during the first trimester of pregnancy;
- due to hypersensitivity to the components of the drug.
Use during pregnancy and lactation
As indicated by the instructions for use for "Ferrum Lek" in ampoules, intramuscularly it is prescribed to pregnant and lactating women.
In the process of controlled studies in the framework of the use of the drug in the second and third trimesters of pregnancy, no negativeeffects on the mother and her fetus. There were also no harmful effects on the fetus during the use of the drug in the first trimester of pregnancy.
Use in children
Doctors consider it possible to use the drug according to indications and doses that take into account the age of the patient. For children under twelve years of age, due to the need to prescribe the drug in a small amount of dosing, it is preferable to use it in the form of a syrup.
For "Ferrum Lek" in ampoules, a prescription is required.
Special instructions for use
It should be noted that chewable tablets, as well as syrup, do not stain tooth enamel. The drug, which is dispensed in an injectable form, must be used exclusively in a hospital setting. When prescribing Ferrum Lek to diabetic patients, it is important to consider that one chewable tablet contains a milligram of syrup.
Against the background of anemia caused by infectious or malignant diseases, iron can accumulate in the reticuloendothelial system, from where it can be mobilized, and then utilized only after the complete cure of the corresponding disease. Micronutrient intake will have no effect on fecal occult blood test results.
Interactions with other drugs and effects on driving ability
This drug does not have any effect on the ability of a person to the necessary concentration of attention, thus allowing, without fear, to managevehicle.
Means "Ferrum Lek", intended for intramuscular injection, can not be used in parallel with the same drug for oral administration. Simultaneous use with ACE inhibitors can enhance the systemic effects of parenteral agents containing iron.
"Ferrum Lek" in ampoules: reviews
Among the reviews about the Ferrum Lek drug that are found on the Internet, there are very common reports of the occurrence of so-called bruises that form after intramuscular injection of the drug into the body. People write that such formations do not pass for quite a long time.
Commenting on these complaints, the developers do not consider the aforementioned drawback to be a side effect, explaining that the likelihood of such phenomena directly depends on the competent and correct administration of the drug. In order to avoid bruising, you should simply strictly follow all the instructions contained in the annotation.
Feedback on the use of "Ferrum Lek" for children
Approximately eighty percent of reviews of Ferrum Lek for children are positive, which can be explained by the high effectiveness of this product and its easy tolerance by young patients, as well as ease of use.
Parents write that many children really like the taste of syrup, so they use it for treatment with great pleasure.
As for the negative reviews, almost all of themdue to all sorts of subjective circumstances that were the reason for the impossibility of using the drug. In most cases, parents were forced to stop giving Ferrum Lek, because their children, unlike the rest, on the contrary, did not like the taste of the syrup. Another reason for dissatisfied parental feedback was the likelihood of constipation in young patients.
Reviews of pregnant women about "Ferrum Lek"
Most of the reviews about Ferrum Lek against the background of pregnancy in women are also positive. Women write that they like the effectiveness of the drug, the need to take it only once a day, and also enjoy its pleasant taste.
In addition, it is noted that "Ferrum Lek" increased the level of hemoglobin even against the background of situations where initially pregnancy in women was accompanied by anemia.
Negative feedback about "Ferrum Lek" in single examples is associated with its ineffective impact. But a predominantly negative sediment was manifested due to subjective factors, for example, due to the fact that someone did not like the taste, someone had nausea or constipation due to its use. Thus, most negative reviews contain information related to the side effects of this drug.
In conclusion, it should be noted that the medical preparation "Ferrum Lek" is by far the most commonly prescribed by doctors remedy for replenishing iron in the body of both children and adult patients, and also as a prevention of iron deficiency.trace element during pregnancy.
Ferrum Lek: cheap analogues in ampoules
Similar in composition and therapeutic effect to the solution "Ferrum Lek" are the preparations "Iron polym altose", "M altofer", "Fenyuls complex", "Ferry".
