Staphylococcus itself is a dangerous bacterium for the body. In some way, it gets to a person and begins its harmful activity: it causes unpleasant diseases. The biggest danger of this bacterium is that it can harm almost any organ.
Of course, first of all, you should protect yourself from staphylococcus aureus, but if you failed to protect yourself, you need to know what medicines for control and prevention exist. It is one of these drugs that will be discussed in this article.
"Staphylococcal antiphagin" - a drug belonging to the group of antimicrobial action. It is a toxin neutralized by formalin and heat, purified from ballast proteins (soluble thermostable Staphylococcus antigens). The drug does not contain preservatives and antibiotics. With the correct injection (according to the scheme), a vaccinated person develops specific antimicrobial immunity to staphylococcal exotoxin(active immunization), which prevents re-infection and reduces the duration of treatment. To do this, it is advised to use "Staphylococcal Antifagin" (instructions for use are given below).
Composition
The main ingredient of the drug is a 1 ml vaccine (peptidoglycan and teichoic acid obtained from microbial cells by water-phenol extract).
Additional substance - phenol (0.2-0.05%).
Type and form of issue
Suspension for injection intended for subcutaneous injection, has a light yellow color or transparent, as well as a peculiar smell. In glass ampoules of 1 ml, in cardboard boxes in the amount of 10 pieces. Instructions for use are located inside the package. When using ampoules without a break ring or break point, an ampoule scarifier is additionally put into the pack. Producer: Biomed named after I. I. Mechnikov (Russia).
"Staphylococcal antiphagin": indications
Prevention and treatment of pustular infections caused by staphylococcus aureus:
- Skin disease caused by suppuration (staphyloderma, pyoderma), usually localized in the hair follicles.
- Abscess (abscesses, abscesses, boils, carbuncles).
- Deep eyelid inflammation - hordeolum (barley).
- Purulent inflammation of the apocrine gonads (hydradenitis).
- Acne (acne).
Contraindications
- Acute infections not caused bystaphylococcus, including the recovery period. Treatment is prescribed 30 days after complete remission.
- Diseases of the nervous and endocrine system, circulatory, liver and kidney diseases.
- Tuberculosis in active form.
- Anorexia, dystrophy (severe exhaustion).
- Decompensated heart disease.
Children under 6 years old. Due to the characteristics of the body, children from 6 months to 6 years old are allocated to a separate category (Staphylococcal antiphagin is prescribed six months after birth after consulting a pediatrician):
- bronchial asthma;
- inflammatory dermatosis (eczema);
- chronic inflammation of skin diseases (neurodermatitis);
- Quincke's edema (acute swelling of the skin and subcutaneous tissue or mucous membranes);
- vitamin D deficiency (rickets) stage 2-3;
- chronic eating disorder (malnutrition) stage 2-3;
- diseases of the endocrine system;
- recurrent and asmatic bronchitis.
If a baby weighs less than 2.5 kg at birth (prematurity), treatment is prescribed after reaching normal weight indicators for age.
In case of contact with a sick person in the family, school, kindergartens, at work, etc., the vaccine is used only after the quarantine is lifted. Such measures are needed to ensure that the drug user does not experience complications.
Method and dose of application
The vaccine "Staphylococcal antiphagin"do in the shoulder area or under the shoulder blade. Once every 24 hours (immediately after opening the ampoule), the next injection is administered 20-30 mm lower than the previous one. There is a possibility of alternation of hands and subscapular region. Intramuscular administration of the drug is not allowed. Scheme of administration for children from 7 years old and adults: on the first day - 0.2 ml; on the second - 0.3 ml; in the third - 0.4 ml, and then with an increase of 0.1 ml every day. The course of procedures ends on the 9th day at a dose of 1 ml.
For children 6 months to 7 years of age, start at 0.1 ml and increase by 0.1 ml each day until reaching 0.9 ml.
With a good clinical effect, the course of treatment, at the discretion of the attending physician, can be reduced to 5 injections.
If there is no possibility of daily vaccination, then you can do it every other day, but with an increase in the dose by 0.2 ml.
In severe, frequently recurring diseases of the skin, a second course is prescribed with an interval of 10-15 days. The schedule for administering the vaccine will be exactly the same.
With local and general reactions to the vaccine, treatment is continued after it disappears at the site of the previous injection. Those who have been treated with staphylococcal antiphagin are satisfied with the results.
Side effects and overdose
It is strictly forbidden to use an ampoule with broken integrity, without a name and release date, in the presence of turbidity or sediment, in violation of the storage temperature and expiration date! Such violations of the ampoule or liquid can causecomplications and other issues. You should be especially careful about the above parameters, and use only ampoules that fit this description.
When the vaccine is administered, a local reaction may occur: redness (hyperemia) of the skin area at the injection site of "Staphylococcal antiphagin", mild soreness in the injection area, which disappears on its own after 1-2 days. Sometimes an increase in the inflammatory process in the area of the lesion (after the second injection). These reactions are not a contraindication for continuing treatment for staphylococcal infections.
The general reaction of the body may be accompanied by hyperthermia (an increase in body temperature up to 38 degrees), local induration (infiltration) up to 20mm or severe pain in the injection area, mild weakness and malaise.
However, in the presence of both local and general reactions, it is recommended to increase the interval between the previous and subsequent injections of the drug "Staphylococcal antiphagin" by one day or reduce the dosage.
If other types of reactions to the vaccine are detected or the local and general reactions of the body are aggravated, it is necessary to inform the attending physician of this fact for further decision-making.
In isolated cases, there may be an increase in body temperature above 38 degrees, the most severe pain in the injection area and the formation of large accumulations of lymph and blood under the skin with a diameter of more than 20 mm.
To protect yourself from unwanted consequences, you need to familiarize yourself with the contraindications andconsult with your he althcare professional prior to administering the vaccine.
Signs of overdose with the vaccine have not been identified.
Precautions
The opening of the ampoule occurs with the strictest observance of asepsis (a method of preventing microbes from entering the wound) and antiseptics (mandatory disinfection of the ampoule before opening) in the treatment room. The opened ampoule is not subject to storage, but is used immediately after opening.
No interactions with other drugs have been identified. This is evidenced by medical studies of the Staphylococcal Antifagin vaccine. Reviews of those who used this remedy confirm the effectiveness of the drug.
The vaccine does not affect the ability to drive a vehicle and complex machinery.
Treatment with "Antifagin" can be carried out simultaneously with other general or local therapy (most often antibiotics). The exceptions are immunoglobulins and antistaphylococcal plasmas.
Terms and conditions of storage
Staphylococcal vaccine "Antifagin staphylococcal" is stored in a dry place, protected from light and children. The temperature should fluctuate from 2 to 10 degrees above zero, but not exceed the indicator. Do not expose to low temperatures! The shelf life after the release of the vaccine is 2 years. It is released in the retail pharmacy network according to prescription forms. Failure to comply with the rules of storage may render the drug unusable. A spoiled medicinal product is strictly forbidden to use and inject into the human body.
"Staphylococcal antiphagin" has the following analogues: "FSME-Immun", "Prevenar", "Cervarix", "Gardasil". The choice of this or that drug should be agreed with the attending physician.
