"Strophanthin", a recipe in Latin and a description of the drug will be discussed in this article. If heart failure is observed, it expands the stroke (that is, the amount of blood ejected by the heart into the bloodstream during one contraction) and minute (the amount of blood ejected by the heart per minute into the bloodstream) cardiac volume, helps to better empty the ventricles, resulting in a decrease heart size. The effect of the use of this drug is observed three to ten minutes after intravenous injection. Its maximum effect is reached in the period from half an hour to two hours after saturation is reached. The drug lasts from one to three days.
The recipe in Latin "Strophanthin" may be of interest to medical students.
Chemical and biological processes in the body
There is almost no cumulative effect.
Drug is distributedpretty evenly; to a slightly greater extent, concentration occurs in the tissues of the adrenal glands, liver, pancreas, and kidneys. One percent of the drug is found in the heart muscle. In relation to blood plasma proteins, five percent.
Excreted by the kidneys in its original form, without undergoing biotransformation. Approximately 85-90% is released per day, the plasma concentration of the drug decreases by fifty percent after eight hours. Complete elimination from the body occurs within one to three days.
For the preparation "Strophanthin" the recipe in Latin will be given below.
Indications for use
Chronic heart failure of the second or third stage, various cardiac arrhythmias, including atrial fibrillation, supraventricular tachycardia. Remember that only a doctor prescribes the drug.
Dosage
The recipe for the Latin solution "Strophanthin" states the following:
- The drug is used intramuscularly and intravenously. Only in emergency situations, if the use of cardiac glycosides is impossible - inside.
- For injection, a 0.025% solution of the drug is taken, diluted in a volume of ten to twenty milliliters of glucose solution (5%) or sodium chloride solution with a concentration of 0.9%. This procedure is carried out slowly, about 5-6 minutes (if injected quickly, shock may occur).
- A solution of this drug is also used in drops (in 100 ml of a dextrose or sodium chloride solution of the same percentage concentration as described above). With suchform, the toxic effect develops less frequently.
- Maximum doses of the drug intravenously for an adult: a single dose - two milliliters, that is, two ampoules, and a daily dose - twice as much, that is, 4 ampoules (4 ml, respectively).
- If intravenous administration is not possible, then it is used intramuscularly. To reduce this sharp pain, you first need to inject 5 ml of a solution of procaine (2%), and then through the same needle - the required dose of "Strophanthin K", which is diluted in 1 ml of a two percent solution of procaine. For intramuscular use, increase the dose by one and a half times.
Daily dose for children, or saturation dose, when using a solution of "Strophanthin K" at a concentration of 0.025%:
- newborn baby - from 0.06 to 0.07;
- up to three years: 0.04 to 0.05;
- from four to six - from 0.4 to 0.5;
- seven to fourteen: 0.5 to 1.
The maintenance dose contains half to a third of saturation. Is Strofantin well tolerated? The recipe in Latin will be presented below.
Side effects
From the cardiovascular system: atrioventricular block, bradycardia, ventricular fibrillation, extrasystoles, ventricular paroxysmal tachycardia.
From the gastrointestinal tract: vomiting, nausea, diarrhea, decreased appetite.
From the central nervous system: dizziness and headaches, sleep disturbances and color perception, fatigue, drowsiness, psychosis, depression, confusion, less often - staining of objectsaround in yellow and green colors, "flies" before the eyes.
Other side effects: urticaria, allergic reactions, epistaxis, thrombocytopenia, petechiae, decreased visual acuity, less common thrombocytopenic purpura. If the drug was used intramuscularly, there may be soreness at the injection site.
Recipe in Latin "Strophanthin" can be checked with a doctor.
Use restrictions
Among the contraindications are:
- high sensitivity to the composition of the drug;
- Wolf-Parkinson-White syndrome;
- sinoatrial complete block or intermittent atrioventricular block;
- 2nd degree atrioventricular block;
- glycoside intoxication.
With caution, taking into account the balance of benefits and risks, it should be used in the presence of sick sinus syndrome without an artificial pacemaker, first-degree atrioventricular block, the presence of Morgagni-Adams-Stokes attacks in the history of the disease, the possibility of unstable passage through the atrioventricular node, hypertrophic obstructive cardiomyopathy, cardiac asthma in patients with mitral stenosis (if there is no tachysystolic form of atrial fibrillation), acute myocardial infarction, isolated mitral stenosis with a rare heart rate, etc.
For the drug "Strophanthin" prescription in Latin in ampoules must be givenpharmacist.
Application features
Pregnant women and those who are breastfeeding should not use the drug, as there are no scientific studies confirming the safety of its use.
In the presence of impaired liver function, liver failure should be used with caution. The same applies to patients with kidney failure.
It is possible to use the drug for the treatment of children, since there are no age restrictions for taking it. For the elderly, use with caution.
Special instructions
With maximum caution, it is possible to use the drug in patients who have atrial extrasystole, thyrotoxicosis. Since the therapeutic index is low, close medical supervision and individual dose adjustment are required during treatment.
If the excretory function of the kidneys is impaired, the dose should be reduced to prevent glycoside intoxication.
Hypomagnesemia, pronounced dilatation of the cardiac cavities, hypokalemia, hypernatremia, alkalosis, hypercalcemia, and advanced age contribute to an increase in the likelihood of an overdose of the drug. Special care and control by means of the electrocardiograph are necessary if atrioventricular conductivity is broken. The attending doctor should write out a prescription for the "Strophanthin" remedy in Latin.
If normo- or bradycardia is expressed, as well as mitral stenosis, chronic heart failure develops due tofor a decrease in diastolic filling of the left ventricle. By increasing the contractility of the heart muscle of the right ventricle, "Strophanthin K" contributes to a subsequent increase in pressure in the arteries of the pulmonary trunk, which can cause pulmonary edema or aggravate left ventricular failure. Patients who have mitral stenosis, drugs of this kind are prescribed for atrial fibrillation or in case of attachment of right ventricular failure. If a patient has a WPW syndrome, then "Strophanthin K" helps to reduce atrioventricular conduction, while helping to conduct impulses using additional pathways, bypassing the atrioventricular node and causing the development of paroxysmal tachycardia. As one of the ways to monitor digitalization, monitoring of the concentration of glycosides in plasma is used. This is confirmed for the drug "Strophanthin" by a prescription in Latin and instructions.
If intravenous administration was carried out quickly, then ventricular tachycardia, bradyarrhythmia, atrioventricular block and even cardiac arrest may develop. During maximum exposure, extrasystole may appear, in some cases in the form of bigeminia. To prevent this effect, the desired dose can be divided into two or three injections into a vein, or the first dose can be administered intramuscularly. If the patient was previously prescribed other types of cardiac glycosides, then before injecting "Strophanthin K" intravenously, it is necessary to take a mandatory break from five to twenty-four days, depending on how pronounced the cumulative signs areprevious drug.
Impact on the management of various mechanisms and driving vehicles
During therapy with this drug, it is recommended to refrain from driving and engaging in activities that are potentially dangerous, require high concentration and quick reactions.
Storage time and conditions
Store this medicinal product at a temperature not exceeding 25 degrees Celsius. The place where the drug is located must be inaccessible to children. Shelf life is three years.
Discharged from pharmacies only by prescription.
Many are interested in the "Strophanthin" remedy in Latin and analogues.
You can replace the drug:
- "Korglikon";
- "Amrinon";
- "Celanidom";
- "Adonis-Bromine";
- "Cardiovalen";
- "Dobutamine";
- "Cardompin";
- foxglove leaves and some other means.
Special Instructions
This description of the drug "Strophanthin K" is a simpler and supplemented interpretation of the official instructions for its use. Before purchasing or using the drug for its intended purpose, it is necessary to obtain qualified medical advice and read the annotation, which is approved by its manufacturer. Presentedinformation about this medicinal product is for informational purposes only and should not be used as a guide to self-treatment. Only the attending physician has the right to prescribe the drug, as well as to establish individual doses and application procedures.
Recipe in Latin "Strophanthin"
Strophantinum K
Rp.: Sol. Strophanthini K 0.05% 1.0
D. t. d. N 10 in amp. S. 0.25–0.5 ml slowly into a vein, dilute before that in ten to twenty milliliters of glucose solution (20%).
