Nowadays, quite often people are faced with the problem of pain in the joints, back or spine. In connection with sedentary work, many patients have long been familiar with the diagnosis of osteochondrosis. Even small children often experience pain in the muscles and joints during the accelerated growth of the body. The options are different, but in many cases, doctors prescribe the well-known pain medication Metindol-retard.
Description
This drug is a non-steroidal anti-inflammatory drug. Indomethacin is the active substance of this drug. "Metindol" has an analgesic and anti-inflammatory effect. Also, this drug is able to have an antiplatelet effect.
Form and composition
This medicine is available in the form of tablets. They may be white or yellowish white in color. The surface of the tablet is flat, the edge is cut off. There are 25 tablets in a blister, the blister is in a cardboard box. The main active ingredient is indomethacin. The tablet also contains additional substances such as potato starch, microcrystalline cellulose,magnesium stearate, talc. In addition, this drug is also available in the form of dragees, gels, capsules, ointments, suppositories and ready-made solutions.
Pharmacological action
The drug has anti-inflammatory, analgesic, desensitizing and antipyretic effects. Also, the pharmacological actions of this drug include the elimination of pain and swelling of the joints, the elimination of swelling around the joints and morning stiffness. In addition, "Metindol" fights erythema and contributes to a significant expansion of the range of motion.
Indications for use
The drug has a strong analgesic effect, so it is most often prescribed for pathologies of the musculoskeletal system, as well as for pain syndrome of various origins. The drug has the ability to stop the pain syndrome (conditions such as toothache, lumbago, pain after surgery and traumatic injuries, headache, myalgia, sciatica, neuralgia).
"Metindol-retard" is often prescribed for the following diseases: neuralgic amyotrophy, arthritis, Paget's disease, ankylosing spondylitis, rheumatism, gout. Also, the drug is indicated for inflammatory and infectious diseases, such as pharyngitis, otitis, tonsillitis. Due to the fact that the drug has a good analgesic effect, it is also prescribed for the treatment of pericarditis, secondary hyperaldosteronism, algomenorrhea, adnexitis, inflammatory process in the small pelvis.
Duringtraumatic injuries of muscles, joints or tendons are prescribed "Metindol" in the form of an ointment or gel. Also, an ointment or gel can be prescribed as an anti-inflammatory for joints, for example, with radiculitis, myalgia, lumbago, osteochondrosis, arthritis. The exception is degenerative pathology of the hip and small intervertebral joints.
Contraindications
"Metindol" is contraindicated in congenital heart disease, such as pulmonary atresia or severe coarctation of the aorta. Also, this drug is not prescribed for peptic ulcers of the digestive tract, gastric bleeding, cirrhosis of the liver, ulcerative colitis, aspirin triad, as well as violation of color or visual perception.
Contraindications include arterial hypertension, bronchial asthma, heart and liver failure, pathology of the optic nerve, swelling, impaired blood clotting and hematopoiesis (leukopenia, anemia). Also, the drug is contraindicated in patients with reduced auditory perception and pathology of the vestibular apparatus. Pregnancy and lactation are also contraindications.
With hemorrhoids and proctitis, taking the drug in rectal form is contraindicated. Gel or ointment is not prohibited, while they also have a strong analgesic effect. Children and the elderly, as well as patients with thrombocytopenia and epilepsy, the drug is not prohibited, but its use should be very careful. The drug in the form of a gel or ointment is prohibited for babies under 1year.
Side effect
"Metindol" is a good pain reliever, but while taking this drug, side effects such as nausea, vomiting, anorexia, diarrhea or constipation, abdominal pain and even gastrointestinal perforation can be observed. This is about the digestive system. On the part of the nervous system, headache and dizziness, fatigue or depression, mental disorders and sleep disturbance can be observed. On the part of the cardiovascular system, edema, chest pain, tachycardia, arrhythmia, and increased blood pressure may occur. Allergic reactions occur less frequently. These include erythema nodosum, urticaria, pruritus, skin rash, dermatitis.
For other body systems, rarely, but may cause hearing or vision problems, kidney problems, excessive sweating, vaginal or epistaxis bleeding, breast tightness or enlargement. With rectal use of Metindol-retard, tenesmus, irritation of the rectal mucosa may occur, and chronic colitis may also worsen. With external use of the drug, itching, rash or redness of the skin may occur.
Application
The drug can be used in three ways (externally, internally, rectally). At the first stage of treatment, adults are prescribed 25 mg of indomethacin about 2-3 times a day. The medicine should be taken after meals with milk. If at this dosage the drug is noteffective, the dosage is increased. The medicine should continue to be drunk 2-3 times a day, but the daily rate in this case is 150 mg. It should be borne in mind that the maximum daily dose of the drug is 200 mg. After the desired effect is achieved, the amount of medication should be gradually reduced. The course of treatment is 30 days. If therapy has a long duration, the maximum dose of the drug per day is 75 mg.
Rectally, the drug should be used at bedtime, after a complete cleansing of the intestines. Ointment or gel is applied only externally, 2-4 times a day. The gel should be applied to the affected area of the joints. The adult maximum dose of the ointment per day is 15 cm (the length of the strip from the tube), and the children - half as much (7.5 cm) of the gel or ointment.
Overdose
Overdose of the drug "Metindol-retard" is manifested by nausea, vomiting, severe headache or dizziness, memory may be disturbed and disorientation in time can be observed. In a particularly severe case, paresthesias, convulsions, and numbness of the extremities may occur. In case of an overdose, immediate elimination of the drug from the body is required.
Special Instructions
The elderly and also
patients with kidney and liver disease should use the drug with extreme caution. The drug should also be used with caution in patients with arterial hypertension and heart failure.
Many specialiststhey say that "Metindol-retard" is the best anti-inflammatory drug, but during treatment it is necessary to systematically monitor the function of the kidneys and liver. It is not recommended to use this drug simultaneously with acetylsalicylic acid. Do not apply ointment or gel to the wound skin surface. It is advisable to avoid getting the drug in the eyes. In case of contact, rinse thoroughly with water.
It must be taken into account that the drug adversely affects the management of vehicles and other mechanisms, therefore, during the period of treatment, activities that require increased concentration of attention should be avoided.
Drug interactions
Simultaneous use of indomethacin can reduce the effect of beta-blockers and saluretics, as well as increase the effect of indirect anticoagulants. Using indomethacin together with diflunisal can cause severe gastric bleeding. If this drug is used with probenecid, the concentration of indomethacin in the blood plasma may increase. If you use "Metindol" with digoxin, there is a possibility of increasing the level of digoxin in the blood plasma.
"Metindol-retard". Drug price
The price of the drug depends on the manufacturer, as well as on the form of release. The cost of this drug in tablets ranges from 100 to 150 rubles per blister.
Storage conditions
Keep this medication in a dark place. The temperature should not be lower than 15 and not higher than 25 degrees. Shelf lifeis 60 months.
Analogues
Very often, patients in pharmacies ask for analogues of a certain medicine. Painkillers can be found at any pharmacy. Considering that "Metindol" is dispensed by prescription, you can ask for its analogues. This drug belongs to a group of medicines that can relieve pain in the joints and muscles. This group also includes drugs such as Meloxicam, Diclonac, Pfizer. Also, "Metindol" is included in a group of drugs aimed at treating diseases of the spine and joints. This group also includes such drugs: "Heparoid Lechiva", "Ibuprofen", "Ketorol". In addition, "Metindol-retard" belongs to the group of non-steroidal anti-inflammatory drugs. In this case, Indomethacin-Acri, Paracetamol can act as an analogue.
Reviews
Mostly, the reviews of both patients and doctors about this drug are positive. When patients come to a specialist, they ask to prescribe any means (pills or ointments), but that the medicines be painkillers. Price is also important, as many cannot afford expensive drugs. "Metindol" is a relatively inexpensive and at the same time potent remedy. Therefore, doctors recommend it.
It should be borne in mind that this drug has many side effects, so you need to take it with caution, be sure to consult a specialist (especially if there are any additional he alth problems). In addition, treatment should beunder the supervision of a doctor, it is not worth prescribing this remedy for yourself (as, indeed, others).
