In the article, consider the composition of the drug "Omez" and instructions for it. Fast food and soda, food on the go and bad habits provoke the development of diseases of the gastrointestinal tract such as gastritis, erosion or ulcers of the stomach or duodenum. These are quite common he alth problems in modern man. To cure these pathologies or prevent relapses, doctors prescribe medications that have a protective effect on the mucous membranes of the organs. One of these drugs is Omez. Let's describe this tool in more detail, find out how well it helps. At the end of the article, reviews and analogues will also be given. The composition of the medicine "Omez" raises questions for many.
Mechanism of action
"Omez" is a drug from the group of drugs that have a pronounced antiulcer effect. Against the background of taking the medication, the production of hydrochloric acid decreases and Helicobacter pylori (the main cause of the development of stomach ulcers) is destroyed.
After the first use, assimilation occursthe active substance "Omez" is only 30-40%, however, if regular use is ensured, digestibility will double. The action of the drug is quite fast, the maximum concentration in the blood is observed already 30-60 minutes after consumption. The effect lasts all day. The secretory activity of the stomach is fully restored on the third to fifth day.
A variety of the drug "Omez D" additionally has an antiemetic effect. As a result, the patient ceases to suffer from nausea. This is due to the fact that the perist altic contractions of the antrum of the stomach increase and the tone of the esophageal sphincter increases. Until the end, the mechanism of action of this agent has not been determined. It can be assumed that they have an effect on the area in the brain that is responsible for the activity of the digestive organs.
Composition of the drug "Omez" and release form
The drug is released in:
- capsules;
- lyophilisate for infusion;
- powder for suspension.
Omez, Omez D and Omez Insta have either different compositions or dosage forms. So, Omez and Omez Insta have only one active ingredient in their composition. We are talking about omeprazole in this case. And the composition of "Omez" in capsules, "Omez D", additionally contains the substance domperidone. Release form "Omeza Insta" - powder. Its other difference is that baking soda is present in the list of its auxiliary components, instantlyneutralizing hydrochloric acid. Omeprazole will start working a little later.
Composition of "Omez", "Omez D" and "Omez Insta" for each dosage form
So, first, consider the composition of the drug "Omez Insta" in powder. Its active ingredient is omeprazole. Excipients in the form of sodium bicarbonate; sucrose; xylitol sucralose; xanthan gum; mint flavor.
Composition of "Omez D" in capsules: active ingredients domperidone, omeprazole. As an auxiliary, there are MCC (microcrystalline cellulose); magnesium stearate; sodium carboxymethyl starch; colloidal silicon dioxide; sodium lauryl sulfate; talc.
"Omez" in capsules consists of omeprazole, as well as mannitol; lactose; sodium lauryl sulfate; sodium hydrogen phosphate; sucrose; hypromellose.
"Omez" in the form of a lyophilisate contains omeprazole. And auxiliary components in the form of disodium edetate; sodium hydroxide.
Not available for sale "Omez" in tablets. The composition of the drug in capsules, powder and lyophilisate is described in detail in the instructions.
When is the drug indicated?
Preparations "Omez" and "Omez Insta" are prescribed for:
- gastroesophageal reflux disease (with its various forms);
- gastric ulcer and duodenal ulcer (well treats acute ulceration and prevents recurrence);
- long-term use of NSAIDs (non-steroidal anti-inflammatory drugs); the remedy protects the gastric mucosa from damage, eliminates the symptoms of dyspepsia,caused by anti-inflammatory therapy;
- diseases in which stimulation of the secretory activity of the stomach occurs (peptic ulcer, Zollinger-Ellison syndrome, mastocytosis);
- for eradication (complete eradication) of Helicobacter pylori in the complex therapy of gastric and intestinal ulcers.
What is the other purpose of the drug "Omez"? In children, the remedy effectively treats gastroesophageal reflux and peptic ulcer of the stomach and / or duodenum.
"Omez D" is prescribed in the case of the same indications, when the use of funds based on one omeprazole did not give the desired effect.
So, we have considered the indications for the use of the Omez drug, then we will talk about contraindications.
Does the medication have contraindications?
Contraindications for the use of "Omez" and "Omez Insta" are:
- hypersensitivity to the components of the drug;
- sucrase/isom altase deficiency, fructose intolerance, glucose-galactose malabsorption;
- co-administration of erlotinib, posaconazole, nelfinavir and atazanavir;
- age up to two years (may be used in children from 2 years strictly as prescribed by a doctor);
- body weight less than 20 kg.
"Omez D" is prohibited for patients with:
- internal bleeding;
- intestinal obstruction;
- perforation (perforation) of the digestive tract;
- prolactinoma;
- childrenunder 12;
- lactation.
In pregnant women, the use of any form of medication is possible only if there are strict indications. And "Omez" and "Omez Insta" are allowed to be taken by nursing mothers, since omeprazole does not adversely affect the baby. But, in accordance with the instructions for use, "Omez D" is forbidden to use while breastfeeding.
Why is this the way it is? The fact is that the main difference between "Omez D" and the usual "Omez" is that, according to the instructions, "Omez D" contains another active ingredient - domperidone. This substance stimulates the synthesis of prolactin, the hormone responsible for lactation. Preparations based on it are prescribed for insufficient milk production. This explains lactation in the list of contraindications, that is, the manufacturer is thus insured against possible consequences. True, despite this, "Omez D" is sometimes prescribed for breastfeeding.
Drug Interactions
How does omeprazole in Omez interact with other drugs? Let's figure it out:
- Against the background of this active component, iron is poorly absorbed (and, accordingly, preparations such as M altofer, Sorbifer, Durules), some antifungal agents (Introconazole and Ketoconazole), as well as antibiotics from the ampicillin group (such as Sultasina, Ampicillin).
- Against the background of taking omeprazole in the composition of "Omez" in capsules or powder, the strength and duration of the effect of drugs such asDiazepam, Phenytoin, and indirect anticoagulants (this is Dicoumarin, Warfarin).
- The effect of drugs that have a depressing effect on the hematopoietic system is intensifying (this includes Cordox, Amikar).
Simultaneous reception of "Omez D" and the following groups of medicines is prohibited:
- antacids (drugs that reduce the acidity of gastric juice - Almagel, Rennie) - the effectiveness of Omez D therapy decreases;
- anticholinergics (drugs that block cholinergic receptors - "Dimedrol", "Cyclodol") - the effect of "Omez D" is neutralized;
- macrolides ("Erythromycin", "Azithromycin"), "Nefazodone" and HIV protease inhibitors ("Ritonavir", "Indinavir") - increases the content of domperidone in the blood.
If long-term use of the drug is carried out, especially against the background of the simultaneous use of diuretics (Furosemide, Diuvera), hypomagnesemia may develop. In this case, the doctor may additionally prescribe magnesium-containing products.
Side effects
Also, with prolonged use, the development of adverse reactions of the body such as:
- Disorders of the stool in the form of constipation, in which defecation may be absent for several days. In rare cases, a backlash is observed in the form of prolonged diarrhea.
- Abdominal discomfort - this can be discomfort, and sometimes pain in the abdominal region. Usually, the symptoms increase immediately after taking the next capsule or suspension dose. Also, patients often complain of increased gas formation or, simply,flatulence.
- Stomatitis. An ailment develops due to the antibacterial effect of the drug.
- Disorders of the liver. Decreased activity of liver enzymes is noted. Due to the load on this organ, various pathologies can develop, including hepatitis.
- Nervous disorders. Against the background of long-term use, the work of the nervous system is disrupted. The patient's mood changes dramatically, depressive states, apathy occur. In some cases, there is nervous excitability, irritability.
- Allergic reactions. The nature and intensity of reactions are influenced by the individual characteristics of the patient. Patients complain mainly of skin rashes, severe itching, urticaria. Anaphylactic reactions in severe cases, accompanied by spasms of the respiratory system, are not excluded.
- Increased sweating. Against the background of taking "Omez", there is a violation of the kidneys, due to which the fluid is retained in the body, and the activity of the sweat glands is activated.
- General malaise in the form of loss of strength, drowsiness, headaches, lack of appetite. A common side effect is nausea and vomiting, especially in the morning.
How to drink Omez?
Instructions for use
All types of medicine are used regardless of the meal. The dosage form affects the method of application:
- capsules are swallowed whole with water;
- powder diluted with a small amount of water and immediately taken orally;
- from lyophilisatea solution is prepared and injected into a vein, and this should be done by a medical worker.
The powder from the sachet dissolves with plain water, it is better not to use other liquids.
Terms of dispensing from pharmacies and price
The drug is released to the patient by prescription.
The average cost of the drug may also vary, depending on the form of release:
- The drug "Omez" in lyophilisate 40 mg costs 150 rubles.
- 10mg capsules cost 75 rubles
- 20mg capsules can be purchased for 150 rubles
- In capsules 40 mg costs 270 rubles.
- In capsules 10 mg + 10 mg - 300 RUB
- Omez Insta 20 mg - RUB 80
Medication analogues
Preparations with a similar composition are commercially available. Their action and indications for use are similar.
So this is:
- Omeprazole;
- Losek Maps;
- Ortanol;
- Ultop.
In analogues, the active ingredient is omeprazole. Contraindications, side effects of these drugs are also the same.
It is important to understand that only the attending physician should select a replacement. Self-medication is unacceptable.
Reviews
Reviews about the drug "Omez" abound. It is considered quite an effective remedy for heartburn, gastritis, stomach ulcers. The speed of its action is well known, the result is noticeable after a few minutes.
Doctors prescribe medication for increased secretion of gastric juice.
According to reviews, against the background of the receptionpain in the stomach disappears, heartburn disappears, literally on the second day.
We reviewed the composition and instructions for use of "Omez". It is a drug that is highly effective in the treatment of ulcerative pathologies of the gastrointestinal tract and other ailments that are accompanied by increased production of gastric juice, nausea, and vomiting. Helps pretty quickly and lasts a long time. Side effects, if any, are quite rare.
