Constant tension, stress at work and at home, and other negative factors often lead to more serious problems in the psycho-emotional sphere. Neuroses, neurotic and psychopathic states develop, they are accompanied by anxieties and fears, depressed mood, irritability increases, sleep is disturbed … It is almost impossible to cope with this on your own, and you should not start this state.
Modern medicine has a huge amount of tools that can get rid of unpleasant symptoms and restore the joy of life. An important role in the treatment of such diseases is played by tranquilizers - sedatives and stress relievers. The doctor selects the medication depending on the patient's condition. One of the highly effective tranquilizers can be called a relatively new drug "Tranquezipam".
Benzodiazepinestranquilizers
"Tranquezipam" is an analogue of the well-known for many years "Phenazepam", the first benzodiazepine tranquilizer. It was created in the USSR in the 70s of the last century. Benzodiazepine tranquilizers are second-generation tranquilizers that relieve anxiety, fear, and emotional tension. At the same time, they have little effect on cognitive functions, such as memory, attention, etc. Among their shortcomings is rapid addiction, so they should not be used longer than the period prescribed by the doctor. Most modern psychopharmacological agents belong to this group. Due to the complex effects on the human body, these drugs are strictly forbidden to be used without a doctor's prescription and supervision.
If you want to find out details about treatment with a medication such as Tranquezipam before visiting the doctor, instructions, reviews on the Internet will give a fairly complete picture of the effect of this tranquilizer.
Indications for use
"Tranquezipam" is used to treat many diseases. It is one of the most powerful benzodiazepines with a pronounced anti-anxiety effect.
In addition to the treatment of increased anxiety, irritability, fears and phobias, this drug is indicated for such problems:
- neurotic and neurosis-like states;
- psychopathic and psychopathic states;
- mood instability and mood swings;
- hypochondria;
- convulsive seizures;
- some types of epilepsy;
- instability of the autonomic nervous system (what is commonly called vegetovascular dystonia);
- increased muscle tone with inability to relax, tics, etc.
It is also successfully used in withdrawal symptoms (alcoholism, substance abuse), in the treatment of schizophrenia and for preliminary drug preparation for induction anesthesia. In addition, Tranquezipam is used in neurological practice and anesthesiology. The instructions for the drug contain a complete list of indications.
Issue Forms
Tranquezipam comes in two forms:
- pills;
- solution.
Tablets "Tranquezipam" contain the main substance of the drug bromdihydrochlorophenylbenzodiazepine in the amount of 0, 5 and 1 mg per tablet. The pills are packaged in packs of 50 pieces in dark glass jars or packed in 5 blisters for 10 tablets in cardboard boxes.
"Tranquezipam" in ampoules contains 1 mg of bromodihydrochlorophenylbenzodiazepine per 1 ml of solution. Designed for intramuscular and intravenous administration, sold in ampoules in pallets or packs of 5 or 10 ampoules with an ampoule knife included.
Drug effects
"Tranquezipam" enhances the inhibitory effect of GABA (gamma-aminobutyric acid) on the transmission of nerve impulses. The drug has antiphobic, sedative, hypnotic,anticonvulsant properties, is an excellent centrally acting muscle relaxant (that is, it reduces skeletal muscle hypertonicity).
Antiphobic, or anxiolytic, effect is manifested in a decrease in emotional stress, feelings of fear, anxiety, anxiety. Thanks to the sedative effect, neurotic signs of anxiety and fear also disappear. The process of falling asleep and sleeping improves, disturbing dreams disappear.
The use as an anticonvulsant drug suppresses the convulsive impulse, but does not remove the focus of excitation, therefore it can only be used as an additional remedy in the treatment of seizures of various origins.
When taken orally, "Tranquezipam" is well absorbed from the gastrointestinal tract, the maximum concentration is reached after 1-2 hours. Excreted by the kidneys after 6-18 hours.
How to use
The tablet preparation is taken orally in the usual way. If you are taking Tranquezipam tablets, the instruction limits their intake to the following dosages:
- sleep disturbances - 0.25-0.5 mg half an hour before bedtime;
- for neurotic, psychopathic and similar conditions - 0.5-1 mg 2-3 times a day (after 4 days you can increase the dose to 4-6 mg per day if the drug is well tolerated);
- for fear, anxiety - 3 mg per day, then the dose is increased until the result is obtained;
- for alcohol withdrawal - 2-5 mg per day;
- with muscle hypertonicity - 2-3 mg per day.
If it is necessary to stop fear, anxiety or psychotic states very quickly, the Tranquezipam solution is used. Instructions for use (in ampoules this drug is prescribed less often than in tablets) gives information that it can be administered intravenously or intramuscularly, the result can be obtained starting from 0.5 mg. But even in the most severe cases, the maximum dose of the remedy is 9 mg.
Detailed information about the dosage of the drug in other cases can be obtained by reading the instructions for Tranquezipam. However, it is worth remembering that the maximum daily dose cannot exceed 10 mg.
Be sure to check the doctor's prescriptions with the recommendations given for treatment with a drug such as Tranquezipam, instructions for use. Tablets must be taken in strictly defined doses, otherwise the treatment may be ineffective or even harmful. Therefore, if you have any doubts about the dosage and frequency prescribed for you, or they do not correspond to the instructions, be sure to tell your doctor.
Contraindications
Any tranquilizer has a wide range of contraindications. Tranquezipam did not escape this fate either. It is forbidden to take it with severe myasthenia gravis, severe kidney and liver diseases (for example, with cirrhosis or Botkin's disease). Contraindication is poisoning with medications, such as other tranquilizers, antipsychotics, sleeping pills, as well as poisoning with drugs and alcohol.
Almost absolute contraindication - pregnancy,especially in the first trimester. "Tranquezipam" is able to have a teratogenic effect on the fetus (that is, it disrupts the development of tissues and organs and leads to congenital deformities). If the mother took this drug during pregnancy, then among other effects on the fetus, depression of the central nervous system, respiratory failure and suppression of the sucking reflex in newborns were noted. In addition, the constant use of "Tranquezipam" during the period of expectation of a child can lead to the development of a withdrawal syndrome in a newborn. Therefore, during pregnancy, Tranquezipam is used only for he alth reasons.
In addition, the drug should be discontinued during lactation and another drug should be chosen (or stop breastfeeding during treatment with this tranquilizer, if the need for it is high). If, nevertheless, the condition requires treatment with just such a remedy as Tranquezipam, the instruction warns of possible complications after taking it.
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The drug should not be taken under 18 years of age, as its safety and efficacy in children have not been studied. In addition, among the contraindications are glaucoma (both in the stage of an acute attack and with a predisposition), acute respiratory failure, shock, coma. When using Tranquezipam during severe depression, manifestations of suicidal tendencies are possible. And of course, you should refuse to take a tranquilizer in case of hypersensitivity to any of its components. Therefore, beforetreatment, you must consult a doctor, informing him of all the factors that may be an obstacle to taking the drug.
Side effects
The list of side effects of Tranquezipam, like any similar drug, is also quite large. The patient may experience dizziness, sometimes headache, suffer from fatigue, drowsiness, muscle weakness, complain of impaired memory, concentration and coordination of movements, and even dysarthria - problems with pronunciation (especially if high doses are prescribed), sometimes insomnia. This usually manifests itself at the beginning of treatment, more often in older people and for the first time taking Tranquezipam. Instructions for use contain mandatory information about possible side effects and the frequency of their manifestation.
Also, undesirable, but possible manifestations include muscle reactions - tremors, uncontrolled movements, including the eyes, muscle spasms.
Often there is an inexplicable excited state, euphoria or, on the contrary, excessive irritability, depressed mood, depression, outbursts of aggression. In extremely rare cases, suicidal tendencies and hallucinations occur. But most often, these symptoms appear as a withdrawal syndrome - with a sharp withdrawal or a sharp decrease in the dose of the drug.
If you are sensitive to a medicine, you may experience an allergic reaction, such as itching or a rash. Also, when taking Tranquezipam, patients may complain of dry mouth, nausea and diarrhea, or constipation and other problems with the gastrointestinal tract,eg heartburn, vomiting, loss of appetite, liver dysfunction.
Not so often, but still possible incontinence or urinary retention, impaired kidney function. In addition, there may be a decrease or increase in libido, dysmenorrhea in women. Do not forget about getting used to the drug.
This is not a complete list of side effects, but most of them are extremely rare and may not appear at all with a controlled intake of Tranquezipam. You can reduce or remove side effects with a drug such as Mesocarb.
Precautions while taking Tranquezipam
It is necessary to carefully stop taking this drug: it must be stopped gradually, gradually reducing the dose so as not to cause a withdrawal syndrome. Sudden discontinuation may cause depression, irritability, insomnia, excessive sweating and other symptoms, especially if the drug has been taken for more than 8-12 weeks before.
"Tranquezipam" should not be taken while driving and those whose profession is associated with increased concentration. Alcohol in any form should be avoided during treatment.
If Tranquezipam is taken in the presence of renal or hepatic insufficiency, then it is necessary to monitor liver enzymes and the picture of peripheral blood.
If the patient is taking a tranquilizer for the first time, the dose of Tranquezipam should be lower than for patients who have already taken tranquilizers and antidepressants or who suffer fromalcoholism.
Dependence on the drug occurs with long-term use in doses of more than 4 mg per day. If you have been taking Tranquezipam for more than 3 weeks, the instructions for use recommend that you consult with your doctor about further use.
The drug should be discontinued immediately if the treated person has reactions such as increased aggressiveness, convulsions, feelings of fear, especially suicidal thoughts or hallucinations. Problems with falling asleep, superficial sleep, etc. are also grounds for discontinuing the drug.
Interaction with other drugs
Since such drugs are taken in combination with other medicines, it is necessary to know about the impact of them on each other. So, for example, "Tranquezipam" reduces the effectiveness of "Levodopa", increases the toxicity of "Zidovudine".
If neuroleptic, antiepileptic or hypnotic drugs or muscle relaxants are prescribed simultaneously with Tranquezipam, then the effect of both drugs is enhanced. But the same interaction occurs when taking a tranquilizer and ethanol at the same time, as a result of which alcohol poisoning may increase.
Antihypertensive drugs enhance the reduction in blood pressure during treatment with Tranquezipam.
If you think that your condition requires treatment with a drug such as Tranquezipam, the instructions for use should be studied in advance. If the medicine is really indicated for you, you must inform your doctor about which medicinalfunds are being accepted.
Analogues
Since Tranquezipam belongs to the most extensive and popular group of benzodiazepines, it is easy to find a suitable analogue if necessary. Tranquezipam itself is an analogue of Phenazepam, a fairly well-known tranquilizer. In addition to it, one can note such drugs with a similar effect:
- "Fezipam".
- "Phenazepam-Ros".
- "Phenorelaxan".
- "Elzepam", as well as many others containing the same active substance in the base.
They are similar in action, but may differ in price, some components and, as a result, the presence and severity of side effects. In each case, the drug must be chosen by the doctor, it is he who determines which drug is suitable for the patient - Phenazepam or Tranquezipam. Instructions for use do not consider analogues, but give the name of the active substance, by which it can be determined whether tranquilizers are from the same group, that is, whether they act in a similar way on the same disease.
Reviews
Most people taking Tranquezipam say it's actually a good drug. A wide spectrum of action and, despite a large list, mild side effects, as well as effectiveness, have allowed the tranquilizer to become one of the most sought-after medicines in its field. In simple words: it is an excellent sedative, goodhypnotic. In addition, it acts very quickly, has a cumulative effect. The life of patients quickly returns to normal and becomes calm and joyful. The reviews often mention the fact that a worthy replacement for Phenazepam is Tranquezipam.
Do not forget that treatment with this drug can only be started after a doctor's prescription. The drug is sold by prescription only. Self-medication is extremely dangerous due to contraindications and possible side effects, so the first thing you should study after prescribing Tranquezipam is the instructions for use. The reviews of those who have already used the drug are quite positive, but almost everyone has an important clarification: if you strictly follow the instructions of the attending physician, Tranquezipam can solve many he alth problems, without adding new ones, which will noticeably change life for the better.
