For the treatment of various infectious diseases, antibiotics and antimicrobial substances are prescribed - drugs that act detrimentally on the cell of the microorganism, destroying and killing it. A large number of such drugs have been developed, and recently drugs have been widely used that are effective for infections of various organs.
And now, broad-spectrum antibiotics are most often prescribed, acting on various groups of bacteria. Among these medicines there is such a drug as "Tsiprolet".
Antibiotic or not, what is its effect, what properties does it have? These questions are asked by patients who are prescribed drugs of this group. This medicine is produced by Dr Reddy”s, an international pharmaceutical company that aims to develop new affordable and effective medicines.
Antimicrobials
Antimicrobial substances are represented by several groups. One ofthe most popular and widely used are fluoroquinolones, a prominent representative of which is Tsiprolet. Antimicrobial agents are chemicals that successfully fight microorganisms by disrupting their cell growth and terminating their vital activity. There are no analogues of fluoroquinolones in nature: in terms of their chemical structure, composition and origin, such antibiotics have not yet been invented.
Fluoroquinolones
Fluoroquinolones are substances that destroy bacteria, preventing them from multiplying and growing. Antibiotics have the same effect. However, by definition: antibiotics are substances that are produced by microorganisms, the main action of which is to inhibit and stop the growth and reproduction of pathogenic bacteria. Antibiotics are highly selective: some microbes die immediately under their influence, while others do not react in any way to them presence. Only the bacteriostatic effect of antibiotics has been revealed: they only stop the growth of microorganisms. Antibiotics are obtained only by chemical means. Whether "Tsiprolet" is an antibiotic is not a significant problem, the healing that it brings is important.
Tsiprolet is an antibiotic?
So "Tsiprolet" - an antibiotic or not? There is no answer to this question. Although it is a chemical substance, it has the most pronounced bacteriostatic activity, it affects a wide variety of microbial agents. It is surprising that this drug is used for a long time. It was created in 2007 and still hasn't beenlost its demand due to good antimicrobial activity, availability and a minimum of side effects.
Tsiprolet is used in any field of medicine. What group of antibiotics is represented by this drug, without which not a single home first-aid kit can do? This medicinal substance belongs to the group of fluoroquinolones. This group, like all antibiotics, has a detrimental effect on the bacterial cell. The active substance of Ciprolet and its analogues is ciprofloxacin, which, when it enters a bacterial organism, destroys the DNA enzyme, which leads to a stop in the synthesis of cellular proteins, and kills both adult microorganisms and those that are in the reproduction stage. Quite rarely, resistance or resistance to the drug "Tsiprolet 500" is observed. Antibiotic or not, it doesn't matter. From how to call it correctly and to which group it belongs, its excellent therapeutic effect does not become less. Free penetration into the cell of a medicinal substance, which does not stop either enzymes or the bacterium itself, leads to the fact that DNA synthesis is impossible, the cell stops and stops dividing. And at the same time, irreversible processes occur in the nucleus, cytoplasm and membrane: the microorganism dies.
What explains the popularity of this substance
Many patients use the drug "Tsiprolet". An antibiotic or not is of little interest to people. An excellent result, a minimum of side effects and a low cost of the drug are important.
Amonghis positive qualities should be noted as follows:
- the mechanism of its “hit” on bacteria is unique;
- activity is high;
- A wide variety of infections caused by gram-positive, gram-negative, aerobes, anaerobes, mycoplasmas, chlamydia, mycobacteria can be treated;
- microbes are not resistant to its action;
- good patient tolerance;
- quick creation of the desired concentration for treatment;
- half-life makes it possible to use it twice a day;
- strengthening the effects of other antibiotics when combined with "Tsiprolet";
- compatibility with many types of antimicrobials;
- treatment of infection of any organ or system;
- opportunity to treat children, pregnant and nursing mothers;
- effect when treated with one drug without the addition of other antibiotics;
- excellent tolerance with minimal side effects.
Application. How and how much
Important when familiarizing yourself with the action of the drug "Tsiprolet" instructions for use. Due to the long half-life and prolonged post-antibiotic effect, the antibiotic is prescribed 2 times a day after 12 hours. In severe cases, it is possible to prescribe 3-4 times a day, both parenterally and orally. For severe infections, 500-750 mg is used twice a day, and for mild forms of infectious inflammation, 250 mg at the same frequency. The course of treatment is 7-10 days, and sometimes 14 days.
How to use eye drops
Eye drops are used for inflammatory and ulcerative lesions of various membranes of the eyeball. Drip 1-2 drops into the affected eye every 4-6 hours. And the treatment of a severe infection requires an installation every hour, and in some cases, for example, with a bacterial corneal ulcer, even every 15 minutes with a gradual decrease in the number of injections.
Step Therapy
In severe infectious diseases, “step therapy” is used: first, intravenous administration of the drug is prescribed, and then, when the patient’s condition is alleviated, they switch to tablet forms.
A good effect can be achieved if you use not the Tsiprolet solution, but tablets. Instructions for use indicate that the highest concentration in the blood is achieved by using the drug on an empty stomach in the absence of side effects: nausea, vomiting, dyspeptic disorders.
When used
In all Russian medical institutions, fluoroquinolones are included in the list of vital drugs. Solutions are widely used along with tablets.
meningitis, encephalitis, septic infections, abdominal infections, venerealdiseases, inflammation of the oral cavity.
Treating a toothache?
Some use antibiotics for toothache. "Tsiprolet" helps only if the pain symptom is caused by an infection: pulpitis, gingivitis, periostitis, periodontitis. This is an incomplete list of diseases that can be treated and even achieve good results, a quick recovery and a decrease in the degree of contamination of the blood and other organs with pathogenic bacteria when using the drug "Tsiprolet 500". Antibiotic or not - doctors do not think about this issue when they see how a seriously ill person is recovering.
What are the side effects
It doesn't matter how you call "Tsiprolet" - an antibiotic or not, but it has the same complications when used as this group of drugs. Special, pronounced side effects are not observed. The drug is generally well tolerated. In some cases, drowsiness or insomnia, depression or irritability, headaches, unreasonable fears, absent-mindedness are possible.
Nausea, vomiting, diarrhea, bad taste in the mouth, loss of appetite are symptoms associated with any antibiotic treatment.
From the side of the heart and blood vessels, a drop in blood pressure, heart rhythm disturbances, a feeling of palpitations are possible.
The urinary system also responds to the intake of "Tsiprolet": polyuria, urinary retention, crystalluria, bleeding, glomerulonephritis.
The liver reacts with the occurrence of hepatitis, a decrease in the functional state: an increase in bilirubin, urea in the blood.
Allergic reactionsmay be in the form of a skin rash or even anaphylactic edema. But this can be prevented by a blood test: with an increased number of eosinophils, it is better to stop the drug. The blood may also have erythremia, leukopenia, thrombocytopenia.
The list of side effects is long, but reading reviews of Dr Reddy's antibiotics "Tsiprolet", we can conclude that with proper use, the frequency of adverse symptoms is insignificant - from 3% to 20%. And in only 2.5% of cases, the severity of reactions requires discontinuation of the drug.
Additional recommendations
When using fluoroquinolones, some rules must be followed:
- avoid prolonged exposure to the sun to avoid photosensitivity;
- to prevent kidney stones, drink plenty of fluids;
- use with caution in cerebrovascular accidents, convulsive syndrome, epilepsy, atherosclerosis (severe forms);
- when treating with "Tsiprolet" you should not engage in work related to increased concentration of attention;
- if the treatment is carried out on an outpatient basis, then constant medical supervision is necessary;
- compulsory use of antihistamines, pro- and prebiotics.
Instructions for use indicates that the drug should not be used in children under 15 years of age, pregnant or lactating. However, it was found that the harmful effect of its use does not exceed the positive therapeutic effect that ciprofloxacin has.in the treatment of infections in these patient groups.
Alcohol + Tsiprolet
Antibiotic "Tsiprolet" and alcohol are incompatible. You should not even drink beer if you are undergoing treatment with fluoroquinolones, because in any case, the liver suffers during antibiotic therapy (this is indicated in the instructions), and alcohol not only destroys hepatocytes, but also blocks the activity of ciprofloxacin. In some cases, a violation of the central nervous system up to a coma is possible. And with such a frivolous approach to treatment, recovery cannot occur.
Strengthening or weakening the action of "Tsiprolet"
If together with "Tsiprolet" drugs are used that reduce the pH of gastric juice, then the absorption of ciprofloxacin will decrease. The same happens when iron-, magnesium-, zinc-, aluminum-containing preparations are used together.
Non-steroidal anti-inflammatory drugs and Ciprolet increase the likelihood of seizure activity.
"Tsiprolet" and "Cyclosporine" increase the adverse effect on the kidneys.
Ciprofloxacin potentiates the action of Warfarin, and theophylline slows down the process of removing Ciprolet.
The drug goes well with taking other antibiotics: the effect of each is enhanced.
Release forms. Price
The drug is available in the form of tablets of 500, 250 mg, solutions for intravenous administration of 100 ml, which contain 200 mg of the active substance, and eye drops.
Tsiprolet-500 (antibiotic) can be purchased at any pharmacy without a prescription. Its price is available: eyedrops cost only 60 rubles. 50-90 rubles is a solution for intravenous or intramuscular injections. "Tsiprolet" produced by Dr Reddy's can be purchased in the following packaging: 10 tablets of 500 mg - for 110-120 rubles, a blister of 250 mg - for 50-60 rubles.
Based on the foregoing, the use of "Tsiprolet" for the treatment of infections is extremely effective: with the right dosage, taking into account interactions with other drugs, when choosing in cases of "benefit or risk" ratio, treatment with this drug is safe, affordable and effective.
