The composition of the drug "Octolipen 600" as the main component includes thioctic (or alpha-lipoic) acid. The active ingredient is contained in the amount of 600 milligrams per capsule (or tablet, depending on the form of release).
Composition, storage and sale conditions
Produced in one of three possible forms: tablets, capsules or ampoules with a concentrate necessary for the preparation of solutions for droppers.
The following are used as auxiliary components: in tablets - calcium hydrogen phosphate (white or colorless crystals), magnesium stearate (fine white-gray powder) and titanium oxide - a white dye. The capsules use slightly different substances that provide a partially liquid structure - gelatin, a colloidal suspension of silicon oxide, as well as two yellow dyes: quinoline yellow and "sunset" (E 104 and 110, respectively). Concentrate ampoules are supplied with a solvent mixture of distilled water and soluble EDTA s alt.
Drug action
It has a whole list of positive effects on the body. Among them:
- Neuroprotective - protection of nerve cells, including brain cells, from the negative effects of certain diseases and poisonings. Allows you to slightly reduce the negative effects of neurotoxin poisoning. Increases axonal conduction and trophism of neurons.
- Hypoglycemic - a decrease in the overall level of sugar in the blood. Able to help patients with diabetes in complex therapy in case of polyneuropathy. Use with caution in people immediately after taking insulin or in people with overactive pancreas.
- Hypocholesterolemic - causes a decrease in blood cholesterol levels, so this drug is taken for liver failure, fatty degeneration and other cirrhosis of the liver.
- Hepatoprotective - the drug weakens or eliminates pathogenic effects on the liver, aimed at changing and killing cells. It is taken as part of complex therapy for hepatitis, slowing down the course of the disease and weakening attacks.
- Lipipidemic - measures aimed at reducing the overall level of lipids in the blood; reduces the risk of atherosclerotic plaques on vessel walls.
Thioctic acid is believed to be a powerful internal antioxidant, activated only after passing through the digestive tract.
Alpha-lipoic acid further lowers blood sugar levels and partially overcomes the effect of insulin resistance. By increasing the degree of absorption of glucose by the body, it contributes to an increase in the depositionglycogen in liver tissues. By its properties, thioctic acid is similar to B vitamins, takes part in sugar and fat metabolism in the body, improves the functioning of the hepatic glands due to the conversion of cholesterol into a biologically harmless form (cholesterol metabolism).
The active substance from tablets and capsules is very quickly absorbed into the blood, but it should be remembered that the simultaneous intake of medicine and food slows down the absorption of the drug components. The highest concentration in the body is observed thirty to thirty-five minutes after consumption.
Regardless of the type of intake (oral or infusion), Octolipen 600 is processed in the liver and excreted by the kidneys almost completely - no more than ten percent remains in the body after two half-lives - seventy minutes.
Indications for use
The medicine "Octolipen 600" in the form of capsules is used for polyneuropathy of any origin (diabetic or alcoholic).
Octolipen 600 itself, whose ampoules appear on sale much more often than capsules, has a wider range of applications. The drug is prescribed for the following diseases:
- Liver dystrophy caused by fatty degeneration due to cancer or alcoholism.
- Chronic hepatitis.
- Severe poisoning.
- Overabundance of lipids in the blood due to dysfunction of the organs of the gastrointestinal tract and liver.
- Cirrhotic metamorphoses in the liver.
- Hepatitis A at any stage.
- Mushroom poisoning, includingincluding pale grebe.
Contraindications
Octolipen 600, analogues and other substances similar to it from other groups of drugs have a small number of contraindications. The summary suggests only four non-specialized contraindications:
- Presence of hypersensitivity to the active substance in the preparation, less often to secondary components.
- Pregnancy period.
- Feeding a baby with milk.
- Children under six years of age.
Side effects
The drug "Octolipen 600" has an impressive range of side effects, but most of them are practically not considered, since such reactions occur less often than one in three hundred thousand people. The most common of them include:
- Allergic reactions (ranging from mild hives and/or itching at the point of contact of the product with the mucous membrane to swelling of the respiratory tract and anaphylactic shock).
- Rarely observed gastrointestinal side effects, including gagging, gastric burning and nausea.
- The most common symptoms are low blood sugar (hypoglycemia): fatigue, dizziness, drowsiness - but all of them are relieved quite well by taking a teaspoon of sugar.
Admission rules
"How to take "Octolipen 600"?" many buyers ask. Patients who have received an appointment for the drug "Octolipen 600" should adhere tothe following intake rate: one tablet is taken half an hour before meals on an empty stomach (woke up - drank a pill - waited - ate).
Provides for a one-time daily dose of 600 milligrams: one or two tablets or capsules. At the same time, the duration and dosage of the drug remain under the control of the doctor, and they can be changed depending on the disease.
In order to increase the overall effectiveness for especially severe patients, the drug is administered intravenously over a period of approximately three weeks. Then, after this period, the patient is transferred to the standard course of treatment: one tablet per day.
For administration through a dropper, the drug is prepared according to the following technology: the contents of one or two ampoules of "Octolipena 600" are dissolved in a certain amount (from 50 to 250 milliliters) of saline - the ratio of sodium chloride to the total mass of the mixture is 0.9 percent. The diluted concentrate is consumed, usually within two hours, the introduction into the body is carried out intravenously through a dropper. Such a solution for infusion allows the patient to receive from three hundred to six hundred milligrams of the drug "Octolipen 600" into the patient's body.
Instructions for use, price - all this calls for the careful use of the drug. The drug has an increased vulnerability to the action of sunlight, and therefore the concentrate ampoules should be opened immediately before use. Moreover, even a diluted drug decomposes in the light, forming toxicsubstances. It is necessary to store means in the dark, dry place; the finished solution loses its properties and safety standards after 6 hours.
Overdose
When taking an overdose of Octolipen 600, standard symptoms are observed: severe headaches, loss of orientation, and increased side effects such as nausea, heartburn and vomiting are also observed. Therapy is prescribed, which consists in eliminating the negative reactions of the body. Can be taken: analgin, activated charcoal; gastric lavage or magnesium oxide suspension is acceptable.
Interaction with other drugs
Due to the hypoglycemic effect, the effectiveness of insulin and other drugs for diabetes is greatly increased, so you should carefully monitor the amount of glucose in the blood. Depending on the effect, the dosage and number of doses of antidiabetic agents may vary, however, it is unacceptable to use only Octolipen 600 - the drug will only work in the presence of other drugs.
A certain period of time is needed between taking milk preparations and Octolipen 600. Reviews also suggest that the simultaneous intake of calcium and iron-containing drugs reduces the effectiveness of thioctic acid - at least a ten-hour gap between applications is required. However, Octolipen activates and enhances the anti-inflammatory and antipyretic effects of glucocorticosteroids (heart drugs).
When taken with alcoholthe effectiveness of "Octolipen" is seriously falling, which is why you should refrain from drinking alcohol during the course of taking the drug.
Analogues of the drug
Octolipen 600 is considered the best medicine from this group. Instructions for use, price - all this suggests that this remedy is a good and effective equivalent of many drugs, such as Berlition and Neurolipon, the most common representatives of the same class of drugs.
Customer Reviews
"Octolipen 600" has many positive reviews; as a rule, many patients highly appreciate this drug - it is much cheaper than Berlition, but more effective than Neurolipon, as a result of which it is the most preferred when buying and prescribing.
An ampouled drug is sold at an average price of 380 rubles, while prescription tablets and capsules cost 290-300 rubles.
And remember - take care of your he alth. Do not self-medicate, "Octolipen" tablets 600 should be taken strictly after consulting a doctor. Self-administration of the drug without a doctor's prescription can lead to bad consequences for your he alth, including death.
