In the article, we will consider reviews on the treatment of HPV with Isoprinosine.
A large number of human papillomavirus strains cause various neoplasms of the larynx, skin, genitals and other parts of the body. This virus enters cells, causing them to actively divide, which, in turn, accelerates the appearance of new virus particles, and some types of HPV can also cause malignant cell growth. There are several drugs, one of which is the drug "Isoprinosine" for HPV, whose distinctive advantage is the possibility of using it to treat not only adults, but also children.
Composition of the drug
The drug is available in the form of biconvex oblong tablets of almost white or completely white color with a slight amine odor.
The active ingredient of the product is inosine pranobex. This connection is similar tostructure with "bricks" of DNA that exists in all living beings on the planet, including humans. This is an analogue of special nitrogenous purine bases, due to which the production of new RNA and DNA molecules in human cells is stimulated. This is especially significant for the cells of the immune system, since they divide most actively, consuming a lot of nucleic acids (RNA and DNA are just their varieties). Each tablet of the drug contains five hundred milligrams of the active ingredient.
Properties
What effects can a person get by activating the production of nucleic acids? How does it help the body fight HPV? Isoprinosine promotes these changes:
- The activity of lymphocytes, that is, the central cells of the human immune system, is being restored. It is because of their "inaction" that you can become infected with HPV with the further appearance of neoplasms. According to medical statistics, more than half of the people on the globe are carriers of this virus, but it manifests itself much less frequently due to the low activity of lymphocytes.
- Increases the activity of T-helpers and natural killers - highly specialized immune cells that are responsible for the destruction of cells already affected by the virus.
- Stimulates the release of interferon, that is, a biologically active component that detects infected cells, inhibits the development of the virus in them and attracts natural killers.
- In addition to interferon, the production of other active compounds of the immune system is also enhanced -immunoglobulins, interleukins and so on.
- Activation of other immune cells - macrophages, neutrophils.
Mechanism of action
All of the above effects significantly increase the body's resistance to various infections, especially of viral origin. In addition, the drug "Isoprinosine" with HPV can also directly affect viruses - like interferon, it slows down the reproduction of the virus (it blocks RNA synthesis) inside the cell. Due to this, the rate of spread of the infection through the body decreases, the immune system gets the necessary time (it is stimulated by the drug) in order to gather and overcome the virus.
But all of the effects described are non-specific, which means that they work when a person is infected with both HPV specifically and a variety of other viruses that cause influenza, measles, mononucleosis, shingles, chicken pox and herpes. Therefore, experts advise drinking Isoprinosine for HPV, as well as for other infections. This drug is not prescribed for prophylactic purposes - clinical studies have shown that all the effects of the drug are less pronounced in the absence of infection, which means that there is no point in taking it.
Indications
The drug is used to restore and treat immunity in the following pathologies: herpes, SARS, human papillomavirus infection and others.
Treatment of HPV in women with Isoprinosine is highly effective. Papillomavirus can be very dangerous, itIt is expressed in the form of the appearance of harmless and simple warts or in an oncological form. It is impossible to get rid of the virus completely, but the symptoms can be alleviated. The risk of papilloma growing into an oncological tumor is also reduced.
"Isoprinosine" for HPV type 16 will be effective if used along with other means. The medication is also prescribed when determining genital warts, condylomas, since they occur due to infection of the body with medium-oncogenic and low-oncogenic types of papillomavirus.
How to take Isoprinosine for HPV?
Dosage and administration features
If there are papillomas and other signs of HPV infection, Isoprinosine is allowed to be taken from the age of three. However, it is very important to observe the correct dosage of the agent, since with an increase in the amount, numerous side symptoms and complications can develop. On pharmacy shelves you can find this drug in the form of tablets, each of which contains 500 milligrams of the active substance.
The therapeutic regimen for treating HPV with Isoprinosine does not depend on the specific form of pathology. It can be used with equal efficiency for common warts on the body and hands, and for genital warts, laryngeal papillomas, multiple papillomas and other forms. A number of experts advise drinking "Isoprinosine" and at the same time resorting to other methods of treatment - external cauterizing and antiviral agents, removal of neoplasms, etc. This increases the effectiveness of therapy many times and almostexcludes possible future relapses.
In the treatment of diseases provoked by HPV in adult patients, the following scheme is prescribed: 3-4 times a day, two tablets, that is, six to eight tablets should be taken per day. The duration of admission should be at least two weeks, the course usually lasts from two to four weeks, after which it is necessary to take a break for at least a month. If necessary and under medical supervision, you can repeat the course.
In children
The use of "Isoprinosine" in children is possible from the age of three and weighing at least 15 kilograms. The amount is calculated based on the fact that for five kilograms of the baby's weight there should be half a tablet of funds per day. With a child weighing 15 kilograms, thus, half a tablet is drunk three times a day, 20 kilograms - four times a day in the same dosage, etc. Otherwise, the course does not differ from the treatment of adult patients with diseases due to HPV - the same duration of admission and a break for a month.
With other viral pathologies, there may be changes in the dosage regimen, so when buying a medicine, you should carefully read the instructions, which give recommendations on the treatment of all diseases. It is important not to confuse the description of HPV treatment with the treatment of another disease.
Contraindications
Isoprinosine tablets for HPV are very well tolerated by most people, but there are still a number of contraindications to use. They are predominantly mediated by inosine metabolismpranobex in the human body, which is processed in the kidneys and liver with the production of sparingly soluble uric acid, and this, in turn, can create problems during the use of the drug.
The main contraindications for Isoprinosine are as follows:
- Gout is a pathology in which uric acid is deposited in the joints, kidneys and other tissues. Of course, its increased production as a result of the use of the drug will not improve the course of this disease.
- Urolithiasis, that is, some of its forms, accompanied by the formation of urate stones (from uric acid s alts). Similar to the previous case, the production of additional uric acid can worsen the patient's condition.
- Chronic kidney failure - almost all uric acid, which is formed during the metabolism of the drug substances, is excreted through the kidneys. If their work is difficult, then this substance accumulates in the body in the form of crystals and stones.
- Arrhythmias - it has been determined that the medicine in some cases can disrupt the rhythm of heart contractions.
- Intolerance to the composition of the drug - the appearance of allergic reactions in the form of itching and rashes on the skin makes it necessary to cancel its use.
Side effects
Among side effects, nausea (sometimes turns into vomiting) and dizziness are most often noted, weakness rarely occurs. Use during lactation or pregnancy is not recommended by most experts - inmainly due to the lack of research in this area. Therefore, there is no accurate information about the effect of "Isoprinosine" on the development of the baby or the process of pregnancy. In addition, the drug is forbidden to be taken by patients under the age of three.
Drinking alcohol
During treatment, it is not recommended to drink alcohol, since both ethyl alcohol and the drug are processed in the liver, and the products of this processing are excreted by the kidneys. That is why the load on these organs greatly increases, severe intoxication can appear even when drinking a small amount of alcohol.
Groprinosin or Isoprinosine for HPV?
"Isoprinosine" is a rather expensive drug, and many patients wish to purchase a more affordable analogue. It should be noted that in the full analogue there must be the same active substance as in the original medicine. Generic, unlike the brand, does not pass clinical trials. The absence of costs for them has a positive effect on the cost. Therefore, generics are cheaper anyway. The Russian pharmaceutical market, unfortunately, is not able to offer many analogues with pranobex inosine. So, only one drug is registered - Groprinosin, produced in Hungary and Poland. Due to the presence of the letter s in the Latin name, the name is sometimes written as "Groprinosin" when translated. Its cost is somewhat lower compared to Isoprinosine, but the difference is not too great. For example, when purchasing 20 tablets, the savings will be only from 50 to 70 rubles compared tooriginal tool. It must be said that the quality of "Groprinosin" and "Isoprinosine" is approximately on the same level. If you replace the original with an analogue, you can be sure that both drugs are completely identical.
What other analogues of Isoprinosine can be used for HPV?
Other substitutes for this drug
There are drugs with antiviral activity that are used to prevent and treat infections. Zinerit, Amiksin, Panavir, 5 NOCs, Arbidol, Acyclovir received positive feedback from doctors and patients.
Analogues of the drug differ in immunostimulating and antiviral effects, but are often less effective in comparison with Isoprinosine. Specialists prescribe such drugs in tablets with a similar therapeutic effect in the treatment of chronic viral diseases, HPV: Kagocel, Alpizarin, Lavomax, Hyporamine, Amizol, Ergoferon, Allokin-Alpha, Tiloron”, “Tilaxin”.
Reviews about "Isoprinosine" for HPV
Most doctors and patients state a noticeable antiviral effect of the drug. Experts are pretty unanimous about the drug: "Isoprinosine" works for real, reducing the duration of the disease and softening the signs of infection. It should also be emphasized that the drug is a prescription drug. Only a competent specialist is able to correctly choose a treatment regimen that will organically combine the amount of medicinal substances.
With feedback on"Isoprinosine" for HPV should be reviewed in advance.
