Peptic ulcer affects people regardless of their age, gender or social status. Therefore, it is extremely important to be able to solve the problem without serious side effects. One of these solutions can be considered bismuth subcitrate, which not only destroys the bacteria that causes stomach ulcers, but also protects its surface by forming a film on it.
Pharmacological action
The main effect of the drug is aimed at eliminating infection with the bacterium Helicobacter pylori, which causes ulcers and erosion on the surface of the stomach and duodenum. In addition, in the acidic environment of the stomach, bismuth subcitrate forms a protective film that protects the stomach from damage.
In addition, it promotes the activation of its own cytoprotective mechanisms, increases the synthesis of prostaglandins and bicarbonates. As a result, after taking the drug, not only the cause of the ulcer is eliminated, but alsoincreased protection of the gastrointestinal tract. To convert bismuth into a protective film, the strongly acidic environment of gastric juice is required.
Indications
The main indications for taking bismuth subcitrate are peptic ulcer of the stomach and duodenum, caused by the influence of the bacterium Helicobacter pylori. Also, the drug is indicated for use in gastritis (both associated with a bacterial infection and not), externally for skin diseases and eczema.
The drug showed itself well in the treatment of inflammation of the gastrointestinal tract, which appeared due to long-term use of drugs from the group of non-steroidal anti-inflammatory drugs.
The introduction of bismuth preparations into the therapeutic regimen also helps to improve the overall protective functions of the stomach if the patient is at risk of developing damage.
In the treatment of gastric and duodenal ulcers with medicines, the drug is included both in the kit for the complex therapy of the disease, and is used as a single drug. However, it is recommended, nevertheless, to combine it with other means. This will increase the chance of a quick cure.
Instructions for use
According to the instructions for the use of bismuth subcitrate, the frequency of taking tablets depends on the age of the patient. An adult needs to take one tablet four times a day, while a child from 8 to 12 years old needs to take one tablet twice a day.
After taking the pill, take a small amount of water. The duration of the course of admission is from 4 to 8 weeks, after which you needtake at least 8 weeks of break, during which it is not recommended to take drugs containing bismuth.
In the presence of damage caused by Helicobacter pylori, drugs with bismuth are used as part of combination therapy and are used strictly according to the scheme: 1 tablet of bismuth subcitrate twice a day, 1 tablet of clarithromycin twice a day and 1 tablet of amoxicillin twice a day. It is also recommended to use proton pump inhibitors in therapy. With this form of treatment, bismuth preparations contribute to maximum protection of the stomach and duodenum.
After successful treatment, you should continue taking the bismuth drug to eliminate the possibility of relapse and protect the stomach from possible damage. It is advisable to limit the use of the drug to 6 weeks, since long-term use of the drug can cause negative side effects.
Contraindications
Although bismuth subcitrate is considered a safe drug, it should not be taken by patients with known renal impairment. It is also necessary, if possible, to replace the drug if the patient is under 14 years of age. If pregnant or breastfeeding, the use of the drug is allowed with caution.
Analogues
Bismuth subcitrate is represented on the pharmaceutical market by such drugs as "De-Nol", "Vis-Nol". Also similar in action are drugs from the antacid group, since they also provide protection of the stomach with the help offilms on its inner surface. These include Almagel, Maalox, Rennie and many others.
Special Instructions
Use may cause black discoloration of stool. Bismuth subcitrate and analogues require exclusion from the diet of liquids and foods that reduce the acidity of gastric juice, as well as antacids. This is done because acidic gastric juice is necessary for the drug to form a protective film for gastroprotective action.
It is highly undesirable to use the drug for a long time (more than two months), as there is a risk of developing encephalopathy. However, such an effect is unlikely when the correct dosages are observed.
There is a small chance of side effects that interfere with concentration and attention, so you should be careful when driving while taking medications containing bismuth.
When taking any medication with bismuth, you should refrain from using other products containing the same substance. The use of several analogs may lead to an increase in the amount of bismuth in the blood and, as a result, the risk of developing unwanted side effects, including effects on the nervous system.
