"Proflosin" - a drug intended for use in urinary problems that are associated with benign prostatic hyperplasia. This tool is an alpha-blocker.
The active ingredient is tamsulosin, a substance that acts on the neck of the bladder, reduces its tone, and has a relaxing effect on smooth muscles. Such an effect on the body allows you to remove the symptoms of the disease and irritation, improves the outflow of urine. The composition contains additional components that enhance the effect of the use of the drug. Consider what the medicine "Proflosin" is. Indications, feedback on its use, effectiveness are presented in the article.
When there is pain during urination and it seems that the bladder is never empty, while the stream is weak, you need to urgently visit a urologist. Usually such conditions require the use of Proflosin. Patient reviews show that the drug can be used,regardless of the stage at which the disease is.
Release form, composition
The drug is available in the form of capsules, the shell of which dissolves in the intestine. Gelatin capsules, they have a prolonged action. In addition to the active substance, the composition contains triethyl citrate, a copolymer of methacrylic acid and ethyl acrylate, cellulose, talc.
Pharmacokinetics, indications
After entering the body, the active ingredient is almost completely absorbed from the gastrointestinal tract in a short period of time. This process is disturbed after eating food, in such cases it proceeds more slowly.
As a result of taking the drug with the active substance in the amount of 0.4 mg, which corresponds to a single dose, the maximum concentration of the main ingredient in the blood is detected after 6 hours.
Reviews of "Proflosin" show that it has a good connection with blood proteins - 99%. The drug is characterized by a slight distribution - 0.2 l / kg. Metabolism occurs in the liver, this task is performed slowly, after its implementation, metabolites are formed. A large part of the drug does not change its shape and enters the bloodstream unchanged.
The active ingredient and the substances resulting from its processing are excreted mainly in the urine, while a small part of the drug (9%) is excreted unchanged from the body. If the drug was taken after a meal, the half-life is in ten hours, if its use is regular - in 13 hours.
Taking Proflosin means reviews of doctors and patients are allowed for dysuric disorders that develop against the background of prostatic hyperplasia (benign character).
Contraindications
The medicine is contraindicated in case of hypersensitivity to its components. Treatment with this agent is not recommended for orthostatic hypotension, even in history. Do not take the drug in the presence of arterial hypotension, severe liver failure. If treatment is prescribed to a patient with chronic renal failure, when CC is less than 10 ml / min, careful medical supervision is required.
Use of the drug, choice of dosage
"Proflosin" patient reviews, instructions are recommended to be taken once a day. The product must be used after the first meal. One capsule must be swallowed without violating its integrity. You need to take your medicine well. The division of the capsule into parts can disrupt the rate of absorption of the active ingredient. The course of treatment has not been established, the drug is taken as needed, the treatment period is not limited.
Side effects
Disturbances may occur in the gastrointestinal tract, in the nervous system. Possible damage to the reproductive system, heart and blood vessels. During treatment with the product, you can notice changes in the skin and tissues located under the skin.
A man can find problems with ejaculation, in very rare cases, patients develop priapism. Significant deterioration in well-being is possible whenthere is a headache, dizziness, sometimes the person is in a pre-fainting state.
After taking Proflosin, patient reviews note that angioedema occurs from skin manifestations, urticaria, skin itching develop, and a rash appears. But this happens very rarely. A person can suffer from diarrhea and constipation. It is likely that side effects will include nausea with vomiting, hypotension (orthostatic), tachycardia.
In a few cases, small pupil syndrome develops as a result of cataract removal, rhinitis, asthenia.
No cases of overdose have been reported. But theoretically there is such a possibility. With an overdose of the drug, blood pressure may decrease, tachycardia may occur. To normalize the pressure, heart rate, you need to lie down a bit. It is pointless to prescribe hemodialysis to the patient, since the active component of the drug binds very well to plasma proteins. Action is required to stop the absorption of the drug - gastric lavage, the use of an osmotic laxative or activated charcoal.
Special Instructions
When there are signs of orthostatic hypotension, such as weakness, dizziness, the patient is placed or seated, the necessary manipulations are performed.
Before starting therapy, during which it is planned to use the drug "Proflosin", the use, composition, reviews are of interest to the patient in the first place, but special instructions forits use also deserves attention and helps not to harm he alth even more. Starting therapy, one must be sure that the patient does not have conditions whose symptoms are similar to prostate lesions - benign hyperplasia.
Before and during treatment, a regular digital rectal examination should be performed, if necessary, a PSA level determination.
With the development of angioedema, the drug is canceled and is no longer prescribed again. In the presence of a cataract and an operation to remove it, taking Proflosin can lead to the appearance of a small pupil syndrome. To exclude such a result, the surgeon must perform special preoperative preparation, the operation must also be performed correctly.
When treating with Proflosin, patient reviews recommend caution when driving vehicles and engaging in activities that can be life-threatening with a decrease in concentration of attention, the speed of psychomotor reactions, since dizziness sometimes appears.
Drug Interactions
As a result of taking the drugs Teofillin, Nifedipine, Enalapril, Atenol, there is no interaction with tamsulosin.
With the simultaneous use of the drug with "Cimetidine", there is an increase in the level of the active substance tamsulosin in the blood. "Warfarin", "Diclofenac" contribute to a more rapid excretion of tamsulosin from the body. When combining the drug "Proflosin" with drugs similar to it, a decrease in blood pressure is possible.
When combined with Furosemide, a decrease in the concentration of the active ingredient of the drug is observed, however, in this case it is not necessary to increase the dose of Proflosin, since after a decrease in the concentration, the active substance retains a normal dose sufficient for therapy with Proflosin. Reviews, instructions, price, description - all this information matters when choosing a particular drug for treatment. Consider the reviews left by doctors and customers, find out the approximate cost of the drug.
Medication cost, analogues
Before using Proflosin, the price, instructions, reviews are in most cases carefully studied by the patient. The cost of one package of capsules is approximately 400-500 rubles.
From analogues, we can distinguish "Revokarin" and "Tulozin". Other drug substitutes are also known, for example, Focusin, Omnic.
Reviews
After reviewing the reviews of the drug, we can talk about its high efficiency. Basically, Proflosin is taken by men after 50 years of age, when prostate disease develops. Many patients are satisfied with the result of the treatment, in most cases urinary problems disappear or are less painful for a man.
Some side effects include erection problems, tachycardia and decreased blood pressure. Some patients "Proflosin" did not help,so they had to decide on the operation.
Many doctors choose this particular drug for treatment only if they are sure that their prescriptions will be strictly observed by the patient. Experts say that the need for an operation can be eliminated if the patient correctly uses (regularly and at a certain time) the Proflosin drug. Reviews, instructions, analogues, application, price are now known to you, and after consulting with your doctor, you can start treatment. The specialist will conduct an examination and prescribe a certain dose of medication, which should help in a particular case.
