Fungal lesions of the skin and mucous membranes cause a lot of inconvenience to their "owners". The antifungal drug "Pimafucin" is often prescribed by doctors of various speci alties in clinical practice for the treatment of fungal infections caused by fungi of the genus Candida. Let's look at "Pimafucin", cheaper analogues, which are also successfully used in dermatovenerologic practice.
Pharmacological characteristics of the drug
The main active substance "Pimafucin" (regardless of the form of release) is represented by natamycin. It is an antibacterial drug from the group of polyenes, has a broad antifungal effect. Natamycin has one distinctive feature - it has practically no cases of allergic diseases, and there has been no decrease in the effectiveness of the drug with prolonged or repeated use.
The action of various forms of the drug
One of the formsrelease of the drug "Pimafucin" - tablets (the analogue is cheaper represented by tablet forms of the drugs "Griseofulvin", "Fluconazole"). These drugs work effectively in the intestines. This is due to the fact that the tablets are equipped with a special enteric coating, which promotes the release of the drug only in the intestinal lumen.
Candles "Pimafucin" (a cheap analogue - "Natamycin"), used to treat infection of the vagina with yeast fungi, also show an effective effect. After the introduction, vaginal suppositories melt rather quickly with the formation of a foamy mass containing the active substance of the drug. This mass effectively envelops the mucous membrane of the vagina, especially its upper sections, contributing to a speedy recovery.
Pharmacokinetics of the drug "Pimafucin"
Regardless of the form of the drug or its analogues used, using modern research methods, it was not possible to identify the content of the active substance in the blood or biological fluids. Thus, Pimafucin, cheaper analogues containing natamycin, are active when used externally or locally and do not have a resorptive effect.
Indications for use
Each dosage form has individual indications for use. Pimafucin tablets are used in the treatment of fungal infections of the intestine caused by forms that are sensitive to it. Vaginal suppositories are prescribed for the treatment of various vaginitis,caused by fungi, and a cream with natamycin for the treatment of skin mycoses.
A distinctive feature of the drug is the absence of its effect on the fetus, therefore "Pimafucin" (candles), cheaper analogues can be successfully used during pregnancy.
Methods of using the drug and optimal dosing
In the treatment of fungal diseases of the intestine, a tablet form of the medicinal substance is used (usually 1 tab.4 r / d). In this case, the therapy lasts no more than 1 week.
In the treatment of fungal diseases of the intestine in children from the age of three, the dosage remains the same as in adults, but the frequency of doses is reduced to two times a day. Due to the peculiarities of the pharmacokinetics of natamycin, the dose of the drug and the frequency of administration remain unchanged for children of all ages.
When treating fungal infections of the vagina, it is recommended to administer 1 vaginal suppository at night, in the supine position. It is necessary to carefully and as deeply as possible to enter the drug. The course of therapy: from three to six days. Treatment of the disease must be completed before the start of the menstrual cycle, or begin immediately after its completion.
In the case of fungal diseases of the skin, the drug in the form of a cream is applied to the affected areas from one to four times a day. The duration of treatment in this case is about 3 weeks.
It is worth remembering that if the attending physician prescribed "Pimafucin" (candles), cheaper analogues can be purchased andin online pharmacies, of course, after consulting a specialist. You can also consult an additional pharmacist at a pharmacy, although his recommendations should be treated with caution.
Contraindications for use
Due to the peculiarities of pharmacodynamics, the drug in any form is practically devoid of contraindications for use. The only contraindication in which the use of the drug should be abandoned is hypersensitivity to one or more components of the drug.
Side effects
When using the tablet form of the drug, disorders of the gastrointestinal tract may occur, which are manifested by loosening of the stool, nausea. These symptoms are usually associated with the start of the drug, go away on their own and do not require additional therapy.
When using the drug in the form of a cream, itching and burning may occur in the area of application to the skin. If these symptoms persist after two or three applications of the drug, its use should be abandoned, since the symptoms are likely due to an allergic reaction to the components of the drug.
"Pimafucin": cheaper analogues
Given that the active substance of "Pimafucin" is natamycin, a sufficiently large number of analogues of this drug can be found on the pharmaceutical market. It must be remembered that any analogue of Pimafucin is cheaper than the original. It's connectedboth with the dosage form itself and with the components that make up the medicinal product, the cost of conducting clinical trials to prove effectiveness.
Replacing the candles "Pimafucin", a cheap analogue can be chosen in the form of the drug "Primafungin". Also, an inexpensive analogue of this drug will be Ecofucin. Among similar analogues of this drug, which have in their composition a component that has an antifungal effect other than natamycin, one can note "Griseofulvin" (like cheap agalogs of Pimafucin suppositories) and such a drug as "Nystatin ointment".
Conclusion
The drug "Pimafucin", cheaper analogues containing natamycin, are effective drugs for the treatment of fungal infections, fungus of the mucous membranes, as well as the digestive system. Natamycin is practically safe to use, and therefore can be recommended for use by both adults and children. Choosing an analogue of "Pimafucin" cheaper, you need to pay attention to the safety of the components of the drug, especially its use during pregnancy. In any case, whether you are using an original drug or a generic, be sure to consult a specialist before buying it. After all, only a doctor can prescribe medications and control their intake in order to avoid unwanted effects.
