"Amoxicillin": what treats, release form, indications for use

2024 Author: Curtis Blomfield | [email protected]. Last modified: 2023-12-16 20:44

"Amoxicillin" is an antimicrobial agent with a broad spectrum of action. Which antibiotic group does Amoxicillin belong to? The drug belongs to the 4th generation of semi-synthetic penicillins.

Antibiotic is active against Gram-positive aerobic bacteria:

1. Streptococcus.
2. Staphylococcus.

In addition, the drug exhibits increased activity against gram-negative aerobic bacteria:

• salmonella;
• gonococcus;
• meningococcus;
• Escherichia coli;
• Klebsiellam.

What are Amoxicillin pills for?

Issue form

According to the instructions for use, depending on the disease, different forms of medicine are prescribed. The basis of the drug is amoxicillin trihydrate. Additional substances include magnesium, sodium, polyvidone and others.

The release forms of "Amoxicillin" are:

1. Pills.
2. Capsules.
3. Oral suspensionapplications.
4. Oral solution.
5. Dry substance for injections.

The cost of medicine varies from 60 to 110 rubles. What are Amoxicillin pills for?

What Amoxicillin is used for

According to the instructions for use, the drug is used for bacterial infections that are provoked by pathogens sensitive to its action.

The spectrum of indications for the use of the drug "Amoxicillin" includes:

1. Salmonellosis is an intestinal infection caused by salmonella.
2. Dysentery is a bacterial intestinal infection that is caused by damage to the mucous membrane of the large intestine.
3. Meningitis is an inflammation of the lining of the brain and spinal cord.
4. Endocarditis is a serious disease in which the inner lining of the chambers of the heart is affected.
5. Laryngitis is a lesion of the mucous membranes of the larynx, which is usually associated with colds or infectious diseases such as scarlet fever and whooping cough.
6. Sepsis is an infectious disease that develops with the progression and spread of the infectious process throughout the body through the blood.
7. Sinusitis is an inflammatory lesion of the mucous membrane of the paranasal sinuses.
8. Tonsillitis is an inflammatory lesion of the palatine tonsils, which develops due to the influence of bacteria or viruses on the lymphoid tissue.
9. Pharyngitis is an acute or chronic inflammatory process,localized in the pharynx, affecting its mucous and deeper layers, as well as soft palate tissues, lymph nodes.

What else does Amoxicillin treat? The drug is also effective in the following pathologies:

1. Otitis media is an infectious inflammatory process, which is characterized by instant development and localization in the middle ear cavity.
2. Pneumonia is an inflammation of the lung tissue, usually of infectious origin, with a primary lesion of the alveoli and interstitial tissue of the lung.
3. Bronchitis is a lesion of the respiratory organs, in which the bronchi are involved in the inflammatory process.
4. Cystitis is an inflammation of the bladder, a widespread urological disease of the urinary system.
5. Urethritis - inflammation of the urethra (urethra), caused by damage to the canal wall of various bacteria and viruses.
6. Gonorrhea is a venereal infection that causes damage to the mucous membranes of organs lined with cylindrical epithelium: urethra, uterus, rectum, pharynx, conjunctiva of the eyes.
7. Cholecystitis - inflammation of the gallbladder - one of the most common complications of gallstone disease.
8. Cholangitis - inflammation of the bile ducts.
9. Peritonitis is an inflammation of the parietal and visceral layers of the peritoneum, which is characterized by a serious condition.
10. Enterocolitis - acute and chronic diseases of the digestive tract, characterized by inflammation of the mucous membrane of the small and large intestines.
11. Erysipelas is a serious contagiousdisease, the external manifestation of which is a progressive lesion.
12. Infected dermatoses are inflammatory diseases affecting the skin.

In combination with Metronidazole, the medicine is used to eliminate chronic gastritis or peptic ulcer.

Pharmacological influence

"Amoxicillin" is effective against a large number of pathogens, with the exception of viruses that produce penicillinase.

Amoxicillin begins to act half an hour after consumption, and the effect of the drug lasts for eight hours, therefore, to maintain maximum concentration, the drug is prescribed three times a day.

After a certain period of time, the drug is partially excreted by the kidneys, liver and in small quantities with breast milk, so nursing mothers are advised to stop breastfeeding the baby during therapy.

Pregnancy and breastfeeding

"Amoxicillin" crosses the placenta, in small amounts excreted in milk. If it is necessary to use the drug during childbearing, it is necessary to carefully weigh the probable benefit to the mother and the potential risk to the fetus. With extreme caution, "Amoxicillin" should be used when breastfeeding.

During pregnancy, the drug can be prescribed according to indications for inflammatory diseases. Hisalso used in bacterial infections. But still, "Amoxicillin" with pneumonia in adult women during pregnancy can cause dysbacteriosis, allergic reactions, fungal infection.

Treatment

According to the instructions for use, the dosage of the drug is purely individual. The duration of therapy varies from 5 to 12 days:

1. For oral use, a single dose of the active substance for adults and children from 10 years old (weighing more than 40 kilograms) varies from 250 to 500 mg, with severe disease - up to 1 gram.
2. For children from 5 to 10 years old, a single dose of the active ingredient is 250 mg; at the age of 2 to 5 years - 125 milligrams; for children under 2 years of age, the daily dosage is 20 mg per kilogram of body weight.
3. For adults and children, the interval between doses is eight hours. In the treatment of acute uncomplicated gonorrhea - 3 grams once.

The treatment of acute otitis media is based on antibiotic therapy. "Amoxicillin" for otitis media for adults is prescribed at a dosage of 0.25-0.5 g three times a day. The duration of therapy is 10 days.

Situations in which the drug is prohibited to use

"Amoxicillin" is not prescribed for the following diseases and conditions:

1. Increased sensitivity.
2. Seasonal allergic rhinoconjunctivitis is a chronic inflammatory disease of allergic etiology, in which the mucous membrane is affectednasal cavity and conjunctiva of the eye.
3. Infectious mononucleosis is a viral disease that is accompanied by fever, damage to the lymph nodes, spleen and peculiar changes in the composition of the blood.
4. Liver failure - a set of symptoms characterized by a violation of one or more functions of the liver, resulting from damage to its parenchyma.
5. Lymphocytic leukemia is a blood disease in which among the normal cells that make up the blood, cells with a pathological structure of genes are born.
6. Asthma is a chronic inflammatory disease of the respiratory tract, characterized by asthma attacks of varying duration and frequency.
7. Exudative-catarrhal diathesis is an anomaly that is characterized by a tendency to infiltrative-desquamative changes in the skin.
8. Lactation.
9. With extreme caution, the antibiotic is used for kidney disease, as well as pregnancy and bleeding history.

Can I drink "Amoxicillin" at a temperature

According to the annotation, antimicrobials are also prescribed for patients with elevated body temperature. With the right choice of medicine, its use shows excellent results.

Whether Amoxicillin can be used in a certain situation should be decided together with the attending physician.

In most cases, all of the above diseases are accompanied by an increase in body temperature. Patient feedback confirmsthe fact that "Amoxicillin" in ARVI in adults improves the patient's condition already in the first days of therapy.

Side effects

According to the instructions, when using "Amoxicillin" the following negative actions are likely to occur:

1. Anaphylactic shock is an allergic reaction of origin, a state of sharply increased sensitivity of the body.
2. Rhinitis is a lesion of the mucous membrane of the nasal cavity.
3. Erythema is a severe reddening of the skin, which occurs due to the fact that the capillaries expand.
4. Nettle rash is a skin lesion, dermatitis of allergic etiology, which is characterized by the rapid development of severely itchy areas.
5. Quincke's edema is an allergic reaction to the influence of various biological and chemical factors.
6. Conjunctivitis is an inflammatory process that occurs on the mucous membrane of the eye.
7. Pain in the joints.
8. Fever.
9. Dizziness.
10. Depressive disorders.
11. Stenosis is a persistent narrowing of the lumen of the hollow anatomical structure of the body.
12. Peripheral neuropathies - a violation of brain signaling due to damage to one nerve or group.

When using "Amoxicillin" together with clavulanic acid, the following side effects may occur:

1. Cholestatic jaundice - a condition in which the flow of bile into the duodenum and intestines is impaired due to a decrease in its synthesis or excretion.
2. Epidermal necrolysis is a serious disease,accompanied by rejection of the surface layer of the skin and disruption of the internal organs.
3. Erythema multiforme is an acute inflammatory lesion in the skin or, more often, in the mucous membranes, which is characterized by a large number of elements of polymorphic rashes, as well as a predominantly cyclic course and a tendency to both exacerbate and self-heal.
4. Hepatitis is an inflammatory disease of the liver, usually of viral origin.
5. Exfoliative dermatitis is a group of diseases in which the skin becomes inflamed, reddens, then blisters and peeling are noted.

What can replace "Amoxicillin"

Medications-substitutes for "Amoxicillin" are the following medicines:

1. "Apo-Amoxi".
2. "Ecoball".
3. "Amosin".
4. "Augmentin".
5. "Amoxisar".
6. "Amoxiclav".
7. "Danemox".
8. "Azithromycin".
9. "Hikoncil".
10. "Flemoxin Solutab".
11. "E-Mox".
12. "Sumamed".
13. "Amoxyllate".
14. "Bactox".
15. "Ospamox".
16. "Taysil".

It is not recommended to replace the drug with a similar one on your own. Be sure to coordinate the replacement with your doctor.

Compatibility with spirits

Can I drink alcohol while taking Amoxicillin? With the simultaneous intake of alcoholic beverages with "Amoxicillin" intoxication occurs. The consequences of this combination are as follows:

1. Alcohol reduces the effectiveness of any antibacterial medication. Therapy becomes ineffective.
2. Side effects of the drug in combination with alcohol increase.
3. Medication may induce vomiting, increase irritability and excitability.
4. Dry mouth appears, severe headaches and changes in taste. If these two substances enter the body, then there is a powerful effect on the central nervous system.

What storage conditions does the drug have

According to the annotation, the drug should be stored in a dark place, away from children, at a temperature not exceeding 25 degrees Celsius. "Amoxicillin" is good for 3 years. It is forbidden to use the medicine after the expiration date. The drug is dispensed from a pharmacy with a prescription.

Medication reviews

On the Web, you can often find feedback from patients who talk about "Amoxicillin", which treats almost any ailment, effectively reduces the temperature. Reviews are mostly positive about the medicine.

They note that after the start of therapy, the therapeutic effect appears immediately, it is convenient to take the medication for both adults and small patients for whom there is a suspension.

According to the reviews that "Amoxicillin" treats, we can conclude thatthat a wide variety of diseases. In addition, it is mentioned as an advantage that the drug can be taken during childbearing. Opinions about "Amoxicillin" by pregnant women, as a rule, tell about its increased effectiveness and the rare development of adverse reactions.

Reviews from medical professionals are also positive. But doctors always warn that self-medication is strictly prohibited.

"Amoxicillin" is an effective medicine that eliminates many types of bacterial diseases. What does Amoxicillin treat? With laryngitis, sinusitis, pyelonephritis, tonsillitis, dermatitis, this medicine is often prescribed.

One of the main advantages of an antimicrobial agent, experts consider its acid resistance and bioavailability.

Eating food does not change the pharmacokinetic properties of Amoxicillin. As a result, the antibiotic reaches its maximum concentration in the blood about an hour or two after taking the medicine.