The Foster inhaler is a remedy intended for the treatment of diseases of the respiratory organs, in particular bronchial asthma. According to the instructions, the drug fights both the underlying pathology and its individual symptoms, which allows you to get the most efficiency from its use. In addition, the special design of the aerosol allows inhalation to deliver the drug solution to the lungs with maximum benefit and convenience.
Composition
1 dose of this aerosol contains 100 mcg of the main substance beclomethasone dipropionate and 6 mcg of formoterol fumarate as active ingredients.
Additional substances: norflurane, ethanol, hydrochloric acid.
Issue form
The Foster inhaler is produced as an inhalation aerosol of 180 and 120 doses in aluminum cans. In one packagecontains one aerosol can.
Pharmacological properties
Means "Foster" has a pronounced bronchodilatory effect. Beclomethasone and formoterol present in its composition have different mechanisms of therapeutic action and have additive efficacy in reducing the frequency of asthma attacks.
Beclomethasone is an inhaled glucocorticosteroid that, in pharmaceutical dosages, has an anti-inflammatory effect, eliminates the symptoms of bronchial asthma and the frequency of attacks of this disease. Beclomethasone has far fewer side effects compared to systemic corticosteroids.
Formoterol is a selective β2-adrenergic receptor antagonist, which in patients with reversible obstructive respiratory pathologies promotes relaxation of bronchial smooth muscles. The bronchodilatory effects of this medicine appear within 1-3 minutes after inhalation in a single dose and last about 12 hours.
The combination of these two substances compared to monotherapy gives a more significant reduction in the severity of asthma symptoms, has a beneficial effect on respiratory functionality and reduces the frequency of attacks.
Indications for use
The drug in the form of an inhaler "Foster" is indicated for the main treatment of bronchial asthma, which involves the use of a long-acting β2-adrenergic agonist and a glucocorticoid in onecombination medication.
List of contraindications
In the instructions for use for the Foster inhaler, some contraindications for the use of this medication are indicated, in particular:
- hypersensitivity to ingredients;
- under 12 years of age.
Foster medicine is used with some caution in the following conditions:
- thyrotoxicosis;
- pulmonary tuberculosis;
- bacterial, fungal, viral lesions of the respiratory organs;
- pheochromocytoma;
- hypokalemia of uncontrolled type;
- diabetes mellitus;
- idiopathic hypertrophic subaortic stenosis;
- aneurysm;
- arterial hypertension in severe course;
- atrioventricular block (stage 3);
- serious pathologies of the heart and blood vessels, including the acute period of myocardial infarction, tachyarrhythmia, decompensated CHF, coronary artery disease, prolonged QT interval;
- breastfeeding, pregnancy.
Side effects
Adverse reactions that most often occur when using the drug "Foster" are due to the presence of substances such as beclomethasone and formoterol in the composition of this drug. In most cases, the following pathological conditions and symptoms occur:
- headache;
- hoarse voice;
- cough;
- rhinitis;
- bronchospasm;
- dysphonia;
- signs of throat irritation;
- prolongation of the QT interval;
- change in ECG;
- increased heartbeat;
- muscle cramps;
- tremor;
- dry mouth;
- burning sensation in the lips;
- dysphagia;
- dyspepsia;
- diarrhea;
- allergic dermatitis;
- increased concentration of C-reactive protein;
- flu;
- pharyngitis;
- hypokalemia;
- gastroenteritis;
- candidiasis of the oral mucosa, pharynx and esophagus;
- sinusitis;
- vaginal candidiasis.
The most common side effects are headaches, hypokalemia, palpitations, tremors, cough, QT prolongation and muscle cramps.
In addition, the development of other, rarer side effects is possible:
- thrombocytopenia;
- angioedema;
- increased blood levels of glycerol, insulin, ketone derivatives and fatty acids;
- hyperglycemia;
- fatigue;
- sleep disorder;
- development of hallucinations;
- change in taste;
- anxiety;
- ventricular extrasystole;
- angina;
- atrial fibrillation;
- tachyarrhythmia.
Is it possible to overdose the remedy?
If you use high doses of the drug, the side effects characteristic of formoterol may increase. A person can suffer:
- pain in the head;
- nauseous;
- emeticreflexes;
- trembling hands and feet;
- hypokalemia;
- palpitations;
- sluggishness, breakdown;
- tachycardia;
- an increase in blood glucose levels.
When these alarming symptoms appear, symptomatic therapy will be required. In especially severe cases, hospitalization is prescribed. In addition, it is necessary to strictly control the level of potassium in the blood.
Overdose of beclomethasone can lead to a deterioration in the function of the adrenal cortex. This condition does not require special therapy, and it usually goes back to normal after a few days.
Against the background of regular use of high doses of aerosol, a systemic effect on the body of hormones is observed, which sooner or later will lead to a sympathoadrenal crisis (panic attack).
Foster inhaler instructions
It must be remembered that Foster is not intended for initial treatment. The selection of inhaler dosages, both at the beginning of therapy and at the maintenance stage, occurs on an individual basis and depends on the complexity of the disease.
For adult patients and children over 12 years of age, 1-2 inhalations twice a day are indicated.
Using an inhaler
To effectively treat and achieve the best absorption of the drug in the lungs, it is necessary to learn the correct technique for using the device.
Before the first inhalation or after a 3-day break in an already prescribed treatment, the first dose should be sprayed into the air to checkdevice status. Holding the inhaler with the mouthpiece down, remove the cap, place the mouthpiece in your mouth and tightly wrap your lips around it. After exhaling through the nose, take a long deep breath through the mouth while pressing the valve of the can. After this procedure, you should hold your breath and remove the device from your mouth.
Analogues of "Foster"
In the domestic pharmacological market, the Foster inhalation drug has many analogues. These include drugs of Russian and foreign production:
- Flixotide;
- Bekotid;
- "Salbutamol-Teva";
- "Ingakort";
- Atrovent.
Flixotide
This medication is the Russian analogue of the Foster inhaler. Fluticasone propionate (the main substance) belongs to the category of local corticosteroids and, when administered inhaled in the correct doses, has a pronounced anti-allergic and anti-inflammatory effect, which leads to a decrease in the severity of the symptoms of the disease and the frequency of exacerbations of diseases that are accompanied by obstruction of the respiratory canals (bronchial asthma, emphysema, chronic bronchitis).
Fluticasone propionate effectively inhibits the proliferation of mast cells, lymphocytes, eosinophils, neutrophils, macrophages, reduces the production and release of inflammatory mediators and other biologically active substances: prostaglandins, histamine, cytokines, leukotrienes. What other analogues of "Foster" are known?
Bekotid
This drug is produced in France and is an inhaled glucocorticosteroid with anti-inflammatory activity. This drug is produced in the form of a metered-dose inhalation aerosol and belongs to the pharmacological category of GCS. The main element of the composition - beclomethasone dipropionate - is a prodrug with a weak tropism for GCS receptors. Under the influence of esterases, it is transformed into an active metabolic substance - beclomethasone-17-monopropionate, which has a local anti-inflammatory effect. This analogue of the drug "Foster" helps to reduce swelling of the bronchial epithelium and reduce the secretion of glands, reduces the number of mast cells in the lining of the bronchi, and has a relaxing effect on smooth muscles.
Salbutamol-Teva
The most common Israeli-made inhalation drug, an analogue of Foster. The main active element is salbutamol sulfate, which effectively stimulates β2-adrenergic receptors. In therapeutic dosages, it acts on β2-adrenergic receptors of smooth bronchial muscles, providing a significant bronchodilator effect. This substance helps to prevent and eliminate bronchospasm, increases lung capacity. In addition, it prevents the secretion of histamine, a slow-reacting component from mast cells, promotes the expansion of coronary arteries, and practically does not reduce blood pressure. This analogue of the Foster inhaler has a tocolytic effect: it reduces the tone and contractility of the myometrium andhas a number of metabolic properties: reduces the concentration of K + in plasma, affects the processes of glycogenolysis and insulin release, gives a lipolytic and hyperglycemic effect, but increases the likelihood of acidosis.
The action of the medical agent begins approximately 5 minutes after administration and lasts for 6 hours according to the instructions for use. Analogues of "Foster" should be selected by a doctor.
Ingakort
This is a German medicine that comes in the form of an inhaler. The active substance of the drug is flunisolide hemihydrate, which belongs to the category of local corticosteroids and, when administered inhalation in the correct doses, has a pronounced anti-allergic and anti-inflammatory effect, which leads to a decrease in the severity of the symptoms of the disease and the frequency of exacerbations of diseases that are accompanied by obstructive conditions of the respiratory canals (bronchial asthma, emphysema chronic bronchitis).
Fluticasone propionate effectively inhibits the proliferation of mast cells, lymphocytes, neutrophils, macrophages, reduces the production and release of inflammatory mediators and other biologically active substances - prostaglandins, histamine, cytokines, leukotrienes.
This medication is contraindicated in hypersensitivity, acute bronchospasm, status asthmaticus (as a priority drug), non-asthmatic bronchitis. This is confirmed by the instructions for use for the analogue of the Foster inhaler.
Atrovent
Broncholytican agent that is available in the form of an aerosol. Manufacturer - Germany.
This analogue of "Foster" blocks the M-cholinergic receptors of the muscles of the tracheobronchial tract and suppresses the occurrence of reflex bronchoconstriction. Possessing structural similarity to the acetylcholine molecule, it is considered its competitive antagonist. The release of calcium ions is carried out with the help of mediators, including DAG (diacylglycerol) and ITP (inositol triphosphate). Anticholinergics prevent an increase in the intracellular level of calcium ions, which is observed as a result of the interaction of acetylcholine and muscarinic receptors located in the muscles of the bronchi.
Analogous aerosol "Foster" effectively prevents the occurrence of bronchospasm resulting from the inhalation of cool air, cigarette smoke, the action of various medications, and also directly eliminates bronchospasm caused by the effects of the vagus nerve. With inhalation use, it practically does not have a resorptive effect. The bronchodilation that develops after inhalation of this pharmacological drug is mainly the result of its local and specific effects on the lungs, and not a consequence of its systemic influence.
We reviewed the instructions and analogues of the Foster inhaler. Reviews will follow.
Reviews
There are a lot of reviews on medical websites about both the Foster drug and its analogues. Among them, the Russian analogue of this drug, Flixotide, deserves special attention, which has a lowercost than other means and has a fast action. As for the Foster inhaler, patients characterize it as a very effective remedy for eliminating an attack of bronchial asthma and with the development of obstructive bronchitis. It relieves symptoms quickly and rarely causes side effects.
