The drug "Clomiphene Citrate" is an oral estrogen antagonist, part of the group of nonsteroidal drugs. As a result of the use of this drug, the secretion of LH and FSH of the anterior pituitary gland is significantly increased, the maturation and subsequent growth of follicles is stimulated. Due to this effect, Clomiphene Citrate is prescribed, as a rule, to increase the ability to bear children in female patients. In this case, it perfectly stimulates ovulation, while blocking the action of estrogen in the body. In addition, it should be noted that this agent does not have androgenic or progestogenic activity, and in large doses it can inhibit the secretion of gonadotropins. At the same time, the period of the so-called half-life of the drug "Clomiphene Citrate" is about five to seven days.
This oral non-steroidalremedy in the form of conventional
medicinal pills white. The main component is a substance such as clomiphene. It is this that effectively reduces the ability of steroid hormones to bind to their respective receptors.
Take tablets "Clomiphene Citrate" instruction recommends for the treatment of anovulatory infertility in women. This drug also helps with dysfunctional uterine bleeding. Women who suffer from secondary, dysgonadotropic or post-contraceptive amenorrhea should also start taking this estrogen antagonist. The list of main indications for its appointment, in addition to all of the above, also includes polycystic ovaries, androgen deficiency and Chiari-Frommel syndrome. Patients with established galactorrhea, which developed against the background of a pituitary tumor, are also quite often prescribed Clomiphene Citrate tablets. The reviews also note the positive results of their administration with oligospermia. And, finally, this drug is actively used to diagnose disorders of the so-called gonadotropic function of the cerebral appendage - the pituitary gland.
This remedy should not be prescribed categorically if the patient has an increased individual sensitivity to clomiphene, as well as in case of uterine bleeding of unclear etiology. In addition, it is necessary to refrain from taking the drug in question in severe liver or kidney failure. A tumor or ovarian cyst is also a causefor denial in
prescribing Clomiphene Citrate tablets. They are never taken during pregnancy either.
In conclusion, it should be said about the main side effects that can be caused by taking the mentioned drug. For example, some women may experience headaches, insomnia, dizziness, increased anxiety, depression and fatigue. In addition, there is a risk of visual impairment, cystic ovarian enlargement, pollakiuria, dysmenorrhea or polyuria, and weight gain.
