"Furamag" is a complex drug with pronounced antibacterial properties, which are due to the content of the active substance - furazidin (share ratio with magnesium carbonate 1:1). It belongs to the group of nitrofurans and has a fairly wide spectrum of action. A positive effect is observed in the treatment of classical staphylococci and Escherichia coli, as well as in the neutralization of paratyphoid pathogens; during therapy, there is a regression of symptoms of genitourinary infections provoked by resistant strains.
The ability to maintain for a long time the peak concentration of reagents in the lymph and bile is a distinctive feature of the drug "Furamag" (analogues show a slightly different metabolic dynamics and often do not give the desired result).
Pharmacological action
The mechanism of the reaction is based on a gradual slowdown in the synthesis of nucleic acids. Reagents "Furamaga" affect the respiratory activity of microorganisms by blocking cells with subsequent disruption of the production cycletricarboxylic compounds. At the same time, there is a destructive effect on the cytoplasmic membrane (or biological membrane). Since all important functions of microorganisms are paralyzed, they soon die. However, the effect of the use of the drug takes place even before the onset of a significant reduction in the number of infectious agents: active furazidin begins to break down toxins - a waste product of bacteria - at the primary stage of absorption, which positively affects the patient's well-being. And this is the main feature of the therapeutic course based on the drug "Furamag" (analogs, the prices of which are comparable to the cost of this medication, as a rule, cannot guarantee such a scenario).
Reason for prescription
The expediency of use is determined by the doctor based on the results of the examination. Diagnoses in which the appointment of the drug is relevant: cystitis, pyelonephritis, urethritis, occurring in chronic or acute form, prostatitis, other diseases caused by gynecological infections. "Furamag" provides good he alth dynamics in the elimination of traces of severe burns. As an adjunct, it can be used to treat bronchitis, pneumonia and other pulmonary ailments of a chronic nature.
For preventive purposes (to prevent infectious relapses or during urological operations), the use of the drug is also very justified. In particular, "Furamag" - analogues to a much lesser extent -perfect for the role of "sterilizer" for cystoscopy and catheterization.
Method of application and dosage
"Furamag", the price of which in pharmacies is 350-950 rubles (depending on the form of release), refers to medicines not symptomatic, but a regular intake cycle. In case of violation of the temporary regimen of use, it is necessary to take measures to obtain the next dose as soon as possible. However, it is strictly forbidden to use a double norm of a substance in order to replace a missed dose.
Furamag is an oral preparation. It is consumed immediately after meals and washed down with water (at least 150 ml). The maximum allowable daily dosage: for adults - 300 mg, for children weighing over 30 kg - 150 mg (subject to the "breakfast - lunch - dinner" regimen). For children under 10 years of age, the total dose is determined by the formula: d=5 x m, where d is the maximum amount of the drug for use within 24 hours (mg), m is the weight of the child (kg).
Limitations and side effects
Contraindications to the preparation of the drug "Furamag" (analogs, the composition of which is identical to the indicated agent, are also undesirable for use in these cases) are as follows:
- individual intolerance to the basic components or hypersensitivity to derivatives of the nitrofuran group;
- chronic or acute liver and kidney diseases (including atypical toxic hepatitis);
- pregnancy (breastfeeding period);
- disorders in the body,expressed in acute deficiency of glucose-6-phosphate dehydrogenase.
The overall reaction of organs and systems to taking "Furamag" can be called positive (the active substance has low toxicity and good absorption).
However, in the form of exceptions, the following side effects are likely:
- permanent dizziness;
- anorexia;
- skin disorders in the form of an allergic rash;
- depression;
- drowsy;
- aching pain in the right hypochondrium;
- imbalance in the liver.
Sometimes urine staining occurs.
Interaction with other drugs
"Furamag" is often used in the diagnosis of "cystitis". Drugs targeted at combating this disease, as a rule, are tolerant to other drugs of the same pharmacological group. However, there is a list of undesirable combinations. So, for example, the simultaneous use of "Furamag" and chloramphenicol (ristomycin, chloramphenicol) can lead to inhibition of the hematopoietic function. A negative effect is also observed when interacting with quinol derivatives. Antacids, in turn, prevent the smooth absorption of the active components of the drug, and representatives of the probenecid group slow down the excretion of Furamag from the body, which, naturally, is fraught with side effects.
During the treatment course, you should refusethe use of alcohol and any medications based on it.
The antimicrobial properties of the drug are enhanced by antibiotics related to penicillins and cephalosporins (a similar effect is achieved when Furamag is combined with erythromycin or tetracycline).
Furagin or Furamag: are there fundamental differences?
Both drugs are nitrofuran compounds and do not use injectable forms (only capsules and tablets) in their production. The production of "Furagin" has been established in Russia and the CIS. And Furamag, which is available on the market today, is mainly a product of the Latvian pharmaceutical company Olinapharm.
According to practitioners, there is no serious difference in the mechanisms of action of drugs on the body. Nitrofurans are not classic antibiotics. Their functions are reduced to inhibition of the growth rate of bacteria, which leads to a reduction in the number of microorganisms in a pathogenic colony, but they cannot completely destroy the source of infection. Therefore, the higher price of the drug "Furamag" (analogues - "Furacilin", "Furazolidone", "Furadonin") is dictated solely by the need to import.
Fighting cystitis: trade names of the most effective medicines
Cystitis is a disease “with bad consequences”, which, however, with timely diagnosis, can be completely cured. Among the results of a progressive disease are pyelonephritis and vesicoureteral reflux (the latter is dangerous becauseleads to a complete functional imbalance of the kidneys).
In order to stop (slow down) the inflammatory processes caused by the infection, patients, among other medications (usually antibiotics), are prescribed drugs based on furazidin - most often it is Furagin or Furamag. It is also worth noting that the regression of the disease is also noticeable with complex therapy based on Nimesulide and Furadonin.
Tablets "Furadonin": instructions for use
The drug is equally useful in the treatment of cystitis in both women and men. Absorption in the gastrointestinal tract can reach 97 - 100%, while the active substance penetrates into the brain tissue, the placenta, and is excreted in milk during breastfeeding. The reaction mechanism is a violation of protein synthesis in pathogenic microorganisms at the cellular level.
Inflammation of the kidneys, bladder and excretory ducts, as well as diverse preventive measures aimed at minimizing the likelihood of relapses in the area of the urinary system - in all these cases, Furadonin cystitis tablets can be used for their intended purpose. Among the main contraindications are chronic diseases of the liver and kidneys. In addition, it is not recommended to take the drug to pregnant women and newborns (under the age of 1 month). You should also refrain from breastfeeding.
The normalized daily dose for adults is 600 mg (4 tablets of 150 mg each; a single dose is not more than 300 mg), for children - at the rate of 5-7 mg per 1 kg of weight (in four divided doses). Course duration -at the discretion of the doctor, but not less than 7 days.
Using "Furadonin": special instructions
Tablets "Furadonin" instructions for use defines as a drug for the treatment of acute and chronic cystitis.
A separate paragraph of this manual indicates important points directly related to the treatment process:
- if symptoms of peripheral neuropathy are detected, the drug should be stopped immediately;
- long-term use of an antibacterial substance must necessarily be accompanied by regular medical examinations (in particular, monitoring of liver functions is necessary);
- disorder of the digestive system, which sometimes occurs when using Furadonin, can be combated by reducing the daily dose;
- there are known cases when the drug caused drowsiness in patients, so it is not recommended to drive a car (or other mechanisms) during treatment.
Reviews about "Furadonin" and "Furagin"
Used as a cure for cystitis, "Furadonin" in most patients does not provoke allergic manifestations. At the same time, the hopes placed on him are mostly justified. Given the low cost of the drug and its relatively high effectiveness, it is extremely difficult to find negative reviews about it on the network - positive ratings and neutral comments prevail.
The attitude towards Furagin is somewhat different: despite the fact that this remedy isanalogue of "Furamag", preference is given to the latter. This is the opinion of patients. Doctors talk about drug parity.
