It is difficult to meet a woman who would not be familiar with candidiasis. This disease, also called thrush, is quite common. The cause of the disease is fungi, which do not bother a person for a long time, but are activated when immunity weakens for any reason. Preparations for candidiasis, which are intended either for oral or topical use, can relieve acute symptoms and at the same time strengthen the immune system. About what medicines can be considered the most effective, we will tell in this material.
What is candidiasis?
The cause of unpleasant symptoms is a fungal infection caused by microscopic yeast-like fungi. These fungi are conditionally pathogenic, they are part of the normal human microflora, but they begin to actively multiply when the body's defenses decrease. Candidiasis can affect the mucous membranes of the vagina, mouth, intestines, as well as the skin and nails.
Main symptoms
The main signs of the disease in women are white curdled discharge, itching and burning,pain during urination and sexual intercourse. Candidiasis also occurs in men, however, it manifests itself much less frequently. Usually it is redness, itching and burning, white discharge during urination, pain during intercourse.
Doctors say: the appearance of this disease signals a decrease in immunity, hormonal imbalance. In addition, candidiasis can indicate more serious diseases, which is why if the problem recurs often, you should definitely see a doctor.
Some statistics
Experts say: almost 50% of the population of the planet Earth at least once in their lives faced such a problem as candidiasis. 70% of women were diagnosed with vulvovaginal candidiasis, and 20% had a chronic form of thrush. As for men, about 10% had this disease at least once in their lives. Among all diseases of the urogenital sphere, candidiasis occupies 30% of cases.
The best drugs for candidiasis: which company to choose
Today, there are a huge number of antifungal drugs that can cope with this problem. In order to purchase an effective medicine, you should pay attention to the manufacturer. In order for you not to make a mistake in choosing, we offer you a rating of the best companies that produce the safest remedies for the treatment of candidiasis:
- GlaxoSmithKline;
- Laboratoire Innotech International;
- "Nizhpharm";
- "Biosynthesis".
Drugs produced by thesepharmaceutical companies, have excellent therapeutic properties. Often, one dose is enough to get rid of discomfort. True, it should always be remembered that the wrong duration of administration and dosage can only eliminate external symptoms, but not cure the disease, which practically guarantees a relapse. We must not forget that self-medication is life-threatening, so you should consult a doctor about the use of any drugs for candidiasis.
Best candles: "Livarol"
One of the most inexpensive, but at the same time effective drugs, doctors call candles "Livarol". At the same time, doctors note: the drug is not suitable for those whose disease has developed into a chronic stage - with frequent or prolonged use, the fungus becomes immune to the drug.
The main active ingredient in suppositories is ketocosanol. It disrupts the metabolic processes in the cells of not only yeast fungi, but also dermatophytes, staphylococci and streptococci, thereby causing their death. This drug for candidiasis is recommended for use in the early stages of the disease. The package usually contains 5 or 10 candles.
Pros of "Livarol"
The main advantages of the drug include the fact that it simultaneously has both antifungal and antibacterial effects, while not being an antibiotic. It can be used as a preventive measure. Suppositories quickly eliminate the acute symptoms of the disease due to the fact that the agent with activecomponent in a short time evenly distributed over the entire surface of the vaginal mucosa.
Disadvantages of candles "Livarol"
Of course, this drug for candidiasis has a number of disadvantages. For example, it is not recommended to use it when candidiasis reappears - the fact is that yeast fungi get used to the active ingredient of the drug. Candles should not be used by pregnant women. The drug also has side effects. The main patients called allergic reactions and irritation of the mucosa.
Clotrimazole
Candles "Clotrimazole" are included in the list of the most used drugs for candidiasis. Experts note that they can be used in both chronic and acute stages of the disease. The drug has a persistent antifungal effect, clotrimazole - the active component of the drug - can disrupt the synthesis of ergosterol, which is the main component of the cell walls of yeast fungi. This helps slow down the appearance of new cells or their complete destruction. The result depends on the concentration of the drug.
Drug Benefits
Women who used Clotrimazole suppositories note their low price, effectiveness even in the chronic stage of the disease. Doctors note: the spectrum of action of this drug covers all pathogenic fungi.
Flaws
Like other antifungal drugs for the treatment of candidiasis, Clotrimazole has a number of disadvantages. Oneof the main ones can be called resistance to the drug, which develops in the fungus with the frequent use of suppositories. Do not use suppositories in the first trimester of pregnancy, as well as in case of hypersensitivity to the components of the drug. Negative reactions of the body are also possible, including itching, burning, cystitis.
Pimafucin
Among the best drugs for candidiasis are Pimafucin candles. The drug is well tolerated, no allergic reactions and low toxicity. That is why experts recommend the use of suppositories for the treatment of candidiasis, even during pregnancy and lactation. It should be noted that the active component of the drug - nitamicin - is an antifungal antibiotic, which is characterized by a wide spectrum of action. When using suppositories, the cell membrane of fungal cells is broken, the metabolism inside them is disturbed, which leads to the death of the yeast fungus. "Pimafucin" can be used to treat chronic or acute thrush, as a prophylaxis and complex therapy for fungal diseases.
Drug Benefits
Of course, the main advantage is that suppositories do not pose a threat to the he alth of a pregnant woman and her unborn baby. In addition, the drug is suitable for the prevention of candidiasis, it is not addictive and is able to quickly eliminate unpleasant symptoms, including itching, burning and curdled discharge. Experts point out that candles"Pimafucin" increase the resistance of the female body to any pathogenic bacteria and fungi, at the same time preventing the growth of pathogenic microflora. In order to get rid of a mild form of candidiasis, one package containing three candles is enough.
Cons of the drug
Pimafutsin suppositories have no obvious shortcomings. The only downside is the high cost of the drug. In the list of contraindications, only intolerance to the active ingredient of the drug.
Nystatin
In the list of the most budgetary drugs for the treatment of chronic candidiasis candles "Nystatin". This drug kills yeast quite quickly, but it is ineffective when it comes to bacteria. The active substance of the drug is a polyene antibiotic called levorin. In large doses, it is able to destroy the fungus, and in small doses, it simply slows down their development and reproduction. Doctors recommend using Nystatin suppositories for both acute and chronic thrush. They are also suitable for the prevention of candidiasis, people with weakened immunity can use them.
Nystatin Benefits
Speaking about the merits of the drug, patients note the elimination of unpleasant symptoms the very next day after the administration of suppositories. "Nystatin" is not absorbed into the blood, it has low toxicity. Moreover, even with frequent use, fungi practically do not develop drug resistance.means.
Negative sides
The drug also has disadvantages. First, it is completely ineffective at fighting bacteria. Secondly, candles have a number of contraindications:
- pregnancy;
- hypersensitivity to drug components;
- any liver disease;
- pancreatitis.
Separately worth mentioning about the side effects. Among them, experts note chills, the possibility of developing dysbacteriosis.
Polygynax
Speaking of the most effective preparations for candidiasis, it is impossible not to mention the candles "Polygynax". They are characterized by a combined effect on the body. Among the list of active ingredients is impressive: it is nystatin, polymexin, neomycin sulfate. All three components affect both fungi and bacteria. They literally paralyze and destroy the microorganisms that cause the disease, prevent the further development of the infection and its spread. "Polygynax" is an antibiotic that can be used to treat various infectious and inflammatory diseases. Experts prescribe these suppositories for vulvovaginitis, fungal vaginitis and so on.
Good side of the drug
Candles "Polygynax" are perfect for the prevention of many diseases of the reproductive system. They are well tolerated, while not disrupting the activity of lactobacilli, which are part of the vaginal microflora. "Polygynax" in a short time eliminatesunpleasant symptoms of candidiasis, not being absorbed into the bloodstream. Already after the first application of suppositories, the trophic processes of the vaginal mucosa improve.
Disadvantages of Polygynax
This drug for vaginal candidiasis has a number of negative characteristics: these include the high cost of the drug, adverse reactions, including severe local burning and irritation. In addition, suppositories can leave greasy stains on underwear. The main contraindication is hypersensitivity to the active substances of the drug.
Terzhinan
Speaking about what drug to treat candidiasis locally, it is impossible not to note the candles "Terzhinan". At the moment, they simply have no analogues: the fact is that this drug has four active components at once:
- a broad-spectrum antibiotic called neomycin;
- a component that can destroy Trichomonas - ternidazole;
- hormonal component that can relieve inflammation and eliminate allergic reactions - prednisone;
- antifungal agent - nystatin.
Gynecologists prescribe "Terzhinan" not only for the treatment of candidiasis, but also for any inflammation of the vagina, fungal or bacterial vaginitis.
Key Benefits
Speaking about the positive aspects of this drug, patients and doctors note the absence of negative reactions after application, ensuring a normal pH balance duringvagina, restoration of the integrity of the walls of the mucous membranes. In addition, one cannot fail to say that "Terzhinan" rather quickly eliminates thrush of any severity. The drug can be used to prevent inflammation before surgery or childbirth, as well as to treat other gynecological diseases.
Cons of "Terzhinan"
Among the shortcomings, patients note the high cost of the drug. Doctors do not recommend its use during pregnancy or when planning it. The fact is that the active substance can interfere with the consolidation and further development of the fetus. Another contraindication of the drug is intolerance to its components.
Pills for candidiasis: "Nizoral"
This drug was developed for the local and systemic treatment of fungal diseases. The active ingredient of the drug - ketoconazole - has an antifungal and metastatic effect. "Nizoral" slows down the synthesis of yeast fungi, while changing the composition of the cell membrane, which, of course, leads to the death of the fungus. With blood, the drug is distributed throughout the body, covering all locations of the fungal infection. That is why the drug is perfect for the treatment of candidiasis of the oral cavity, vagina, intestines, skin. It should be noted that the duration of the medication should not be less than five days. Even if the symptoms have already disappeared, the course must be continued. Otherwise, you risk getting fungi that will be resistant to the drug.
Nizoral benefits
The drug is able to eliminate thrush of any severity, while at the same time normalizing the microflora. The active ingredients are not absorbed into the general bloodstream, however, the remedy is very effective in combating fungal infections of different localization - the drug is equally good for skin candidiasis, in the mouth, and vagina.
Negative characteristics
Nizoral should not be taken by patients with severe kidney or liver disease. You should also refrain from using it if you are allergic to the active substances. The drug is contraindicated in women during pregnancy and lactation. He also has not the most pleasant side effects: including a disorder of the nervous system, disruption of the gastrointestinal tract and increased blood clotting.
Fluconazole
When prescribing drugs for candidiasis of the oral cavity, vagina, skin or intestines, doctors often prescribe fluconazole-based drugs to patients. The most common drug with the same name. Fluconazole has a lot of positive feedback: patients note that the active ingredient suppresses yeast enzymes in a short time, which leads to its inability to receive adequate nutrition. This leads to the fact that the fungus cannot multiply and develop. Unlike other drugs for oral or vaginal candidiasis, this medicine can get rid of a mild form of the disease in just one dose - 150 milligrams of the remedy is enough.
Ifthrush often recurs, appeared on the background of taking any antibiotic or developed into a severe form, only a practitioner can prescribe the correct dosage and frequency of administration.
Positives
"Fluconazole" is actively fighting the causative agent of the disease. The drug is suitable for candidiasis in the mouth, intestines, on the skin or in the vagina. In addition, the active ingredient is rapidly absorbed, which ensures the elimination of unpleasant and painful symptoms in a short time - after the first application. Patients also note the long-term effect of the drug.
Disadvantages of "Fluconazole"
Speaking of this drug for candidiasis in the mouth, intestines and other localizations, its side reactions should be noted: including irritation and allergies, disorders of the kidneys, liver, stomach, intestines and nervous system. It should not be taken by pregnant women. The treatment regimen can only be prescribed by the attending physician: if the dosage is incorrect, disorders such as hallucinations and paranoia are possible.
Cancidas
This new generation drug is suitable for the treatment of candidiasis of the intestines, vagina, oral cavity, skin. The medicine is a lyophilisate - a powder for the preparation of infusions. The substance instantly inhibits the synthesis of the main component of the fungal cell.
Drug Benefits
In addition to the treatment of thrush of different localization, the drug has other advantages. Firstly, it can be used by children withthree months - of course, only on prescription. The drug against candidiasis is equally effective in men, women and children.
Flaws
The main drawback of the drug, according to patients, is the intravenous route of administration. The infusion time is quite long - at least one hour. The drug is not recommended for use during pregnancy, breast-feeding while taking "Cansilas" should be canceled. Side effects are also possible: chills, nausea, anemia, rash and itching. Some patients experience sweating, diarrhea, and shortness of breath.
