The Cholisal medication, reviews of which are only positive, is a combined remedy used in dentistry that has anti-inflammatory, analgesic, antimicrobial effects.
Pharmacological properties
The composition of the drug includes choline salicylate, at the site of application it produces an analgesic, anti-inflammatory effect. This component inhibits the functional activity of macrophages, neutrophils, the activity of cyclooxygenase, the production of interleukin-1, and the synthesis of prostaglandins. In the acidic and alkaline environment of choline, salicylate exhibits antimicrobial, antifungal activity.
The antiseptic cetalkonium chloride included in the drug is effective against gram-positive organisms, fungi, viruses, and to a lesser extent gram-negative organisms. Methyloxybenzoate and propyloxybenzoate, contained in the gel base of Cholisal (reviews give the drug a good rating), also produce antibacterial and antifungal effects. Due to the gel base, the medication is firmly fixed on the oral mucosa and is not washed off with saliva.
Quickly absorbed and penetrates tonerve endings medicine "Cholisal". Reviews indicate that already two to three minutes after the application, the pain disappears, and the analgesic effect persists in different people from three to eight hours.
Indications for use
In dental practice, this drug is used for the treatment of infectious-inflammatory, inflammatory, trophic, ulcerative-necrotic diseases of the mucous membranes of the mouth. These pathologies include stomatitis of various etiologies, oral candidiasis, cheilitis, periodontal disease, gingivitis, allergic reactions, injuries of the oral mucosa. To relieve pain, Cholisal is prescribed for teething in children, wearing dentures, and surgical interventions.
Release form, composition
The medicine is produced in the form of a gel. 1 g of the drug contains choline salicylate (anhydrous) in the mass of 87.1 mg, cetalkonium chloride in the mass of 0.1 mg. Auxiliary components are ethyl alcohol, methyloxybenzoate, glycerin, anise oil, propyloxybenzoate, hydroxylcellulose, purified water.
How to use
For local use, the drug "Cholisal" is intended. Reviews report that it is well tolerated by patients. The medicine should be rubbed into the affected areas of the mucosa twice or thrice a day (before / after meals, at bedtime). It is enough for adults to apply a strip of gel 1 cm, for children - 0.5 cm.day. The doctor individually determines the duration of treatment.
Side effects
Usually, the drug "Cholisal" does not cause side effects. Feedback from individuals report that they experienced a burning sensation at the application site, but it was short-lived and passed on its own.
Contraindications
People with hypersensitivity to the ingredients included in the composition are not prescribed the drug "Cholisal". For children in the first year of life, pregnant and lactating women, this drug is indicated, but it should be prescribed with caution.
