One of the current problems for some people is overweight. Often, pathology occurs against the background of a violation of metabolic processes in the body, but there may be other reasons. Depending on the degree of development of the disease, an anti-obesity drug is prescribed, which helps to reduce body weight to normal levels. Let's take a closer look at the most effective means to help cope with excess weight.
Causes of obesity
Obesity is a state of the body in which an excess of body fat appears in tissues, organs and subcutaneous tissue. In addition to psychophysical problems, pathology causes changes in the work of internal systems and organs. According to statistics, women are twice as likely to be obese as men.
The main reason for the appearance of extra pounds is overeating. Excess calories that enter the body with food do not have time to be used up and are deposited in the subcutaneous tissue, on the internal organs. The gradual increase in these fat depots leads to weight gain.
The following factors also contribute to the development of obesity:
- sedentary lifestyle;
- malnutrition (eating a large amount of carbohydrates, eating before bedtime);
- depression, stress, insomnia;
- endocrine disorders;
- dysfunction of the digestive tract;
- impaired hypothalamic-pituitary function;
- use of certain medications (hormonal drugs, antidepressants);
- hormonal changes (menopause, pregnancy);
- violation of metabolic processes.
When should I start taking medication?
Body mass index is the main indicator for determining the stage of obesity. To find out the BMI values, you need to make simple calculations: divide a person’s weight by height (in meters) squared. For example, with a weight of 75 kg and a height of 168 cm, the index will be equal to: 75 / (1.68 × 1.68). After calculation, we get an index value of 26.57. WHO recommends interpreting the results as follows:
- ≦ 16 - Acute underweight;
- 16-18, 5 - underweight;
- 18, 5-25 normal weight;
- 25-30 - there is a slight excess of mass;
- 30-35 - the first degree of obesity;
- 35-40 - the second stage of the disease;
- 40-50 - the third degree of obesity;
- ≧ 50 is overweight.
After determining the stage of development of the pathology and conducting a diagnosis, the specialist must select drugs for obesity. List of drugs that will help in this situation,big enough. Some of them are released strictly by prescription, because they have many contraindications and side effects. Specialists try to resort to the help of drug therapy only if the body mass index is more than 30.
How do drugs work?
Obesity drugs have different mechanisms of action, but they all share the same goal of weight loss and control. Depending on the principle of operation, the following categories of medicines are distinguished:
- Anorectic drugs are drugs that affect the satiety center in the brain and suppress appetite. Due to their action, the patient begins to consume less food. In addition to being well tolerated, the drugs in this group also help to establish a nutritional culture.
- Fat burners - block the absorption of fat, thereby helping to remove it from the body. They are divided into several groups: thermogenetics (increase body heat production), lipotropics (stimulate the liver), dietary supplements (increase bile production) and hormonal drugs (affect the thyroid gland).
- Laxatives - accelerate the process of excretion of intestinal contents, but do not affect body weight.
- Diuretic drugs - remove excess fluid from the body and do not affect subcutaneous fat.
Medicines for obesity: a list
The best medicines for treating obesity are those that have been prescribed by a doctor on an individual basis. The specialist selects the drug depending on the causes of overweight andthe presence of comorbidities. Self-medication in this case can be extremely dangerous.
Obesity drugs listed below are only prescribed when a strict diet and exercise have failed. Strong obesity drugs include:
- Orthosen.
- Xenical.
- Meridia.
- Orlistat.
- "Reduxin".
- Liraglutide.
- Sibutramine.
- "Listat".
- "Lindax".
- Goldline.
- Laminin.
Each of the medicines has both advantages and disadvantages, which must be familiarized with before starting treatment.
Sibutramine for excess weight
"Sibutramine" is an effective anorexigenic drug for obesity. Available in the form of capsules and tablets that contain sibutramine hydrochloride monohydrate. The active ingredient enhances thermogenesis and stimulates the formation of active metabolites that inhibit the reuptake of norepinephrine and serotonin.
As part of complex treatment, "Sibutramine" is taken for alimentary obesity in patients with a body mass index of more than 30. It is also allowed to use the medication for obesity on the background of diabetes mellitus (non-insulin dependent).
Contraindications
With high sensitivity to the constituent components, serious eating disorders, mental disorders, arterial hypertension, severe pathologies of the liver and kidneys, pregnancy andlactation, angle-closure glaucoma, diseases of the heart and blood vessels do not use this medicine for obesity. A new remedy should only be prescribed by a specialist.
Patient testimonials
Many overweight people take Sibutramine. The drug has proven itself on the positive side and really helps to fight obesity. Subject to the recommendations of the doctor, the tablets practically do not have side effects. However, during the treatment period, symptoms such as dry mouth, anxiety, anxiety, headaches, constipation, tachycardia, arterial hypertension may still occur.
"Lindaxa": description of the drug
According to experts, the best medicines for obesity are those that are prescribed on an individual basis and are selected depending on the needs of the patient. The drug "Lindaksa" (Czech Republic) has good therapeutic properties. The therapeutic effect is provided by the substance sibutramine.
Anorectic affects the centers responsible for food saturation. The biotransformation of the active ingredient occurs in the liver, where active metabolites are formed.
The dosage of "Lindaxa" is selected individually and depends on the degree of obesity. The recommended starting dose is 10 mg. The medicine can be taken regardless of food. Increase the dosage to 15 mg should be in the absence of a visible therapeutic effect. Duration of therapy - from 3 to 12 months.
Contraindications to the appointment of the drug has the same as the remedy "Sibutramine". To the frequent side effects that occur against the backgroundtaking "Lindaksa" can be attributed to tachycardia, dry mouth, thirst, dizziness, insomnia.
Reviews about the drug "Liraglutide"
The hypoglycemic obesity drug Liraglutide is used to treat type 2 diabetes mellitus and chronic obesity. The tool is allowed in many countries only in the form of the drug "Victoza" (Denmark). Another trade name for the drug, Saxenda, appeared on the pharmaceutical market in 2015 and positions itself as a drug that helps fight excess weight in adult patients.
"Liraglutide" is a synthetic copy of the glucagon-like peptide-1, which is produced in the human intestine and actively acts on the pancreas and stimulates the production of insulin. The body is not able to distinguish between a natural and an externally introduced enzyme. The use of the drug allows you to gradually adjust the natural production of insulin and reduce sugar levels. This, in turn, normalizes the absorption of nutrients from the products consumed.
Reviews of patients confirm that the drug has a pronounced therapeutic effect. The tool is quite convenient to use, because it has the shape of a syringe pen, on which divisions are applied, allowing you to accurately calculate the dosage. The medicine is injected into the shoulder, thigh or abdomen. This anti-obesity drug is only available in pharmacies with a prescription.
The cost of drugs based on liraglutide ranges from 9,500 (Victoza, 2 syringes) to 27,000 rubles("Saxenda", 5 syringes). Specialists do not often use these medicines for the treatment of patients with diabetes and obesity due to the high cost.
Destination features
It is strictly forbidden to take hypoglycemic drugs for weight loss in obesity without a doctor's prescription! "Liraglutide", "Saxenda" and "Victoza" can not be used for type 1 diabetes, severe liver and kidney pathologies, pregnancy, inflammatory processes in the intestines, heart failure (types 3 and 4), thyroid neoplasms.
Treatment should only be continued if the patient has lost at least 5% of their body weight in 16 weeks. If such results cannot be achieved, it is necessary to choose other drugs to get rid of extra pounds.
Drug "Orlistat"
Orlistat tablets have a peripheral effect and help to lose extra pounds without harm to the body. The main task of the drug is to block the process of absorption and digestion of fats. The anti-obesity drug is able to lower cholesterol and glucose levels, which makes it possible to use it in the treatment of diabetes.
Orlistat is an inhibitor of gastrointestinal lipases. Thanks to this pharmacological action, the penetration of triglycerides into the blood is blocked, an energy deficit appears, causing the mobilization of fat deposits from the depot.
The drug should not be used for hypersensitivity, nephrolithiasis,cholestasis, hyperoxaluria, pregnancy and lactation. Orlistat is not prescribed for children under 12 years of age and people suffering from chronic malabsorption syndrome.
What are doctors and patients saying?
Most of the reviews about the drug contain positive recommendations. Many patients were able to lose about 10 kg of excess weight in 8-12 months with the help of this obesity medication. Reviews of experts saying that "Orlistat" is one of the few drugs that practically do not cause side effects. Occasionally, cases are recorded when the stool and the work of the digestive tract are disturbed, there are frequent urges to defecate.
Means "Xenical"
Another medication based on orlistat is Xenical. The medicine is produced in Switzerland, which significantly affects its cost. You can buy a cure for obesity for 2300-2700 rubles. Xenical is available in the form of turquoise gelatin capsules.
According to the instructions, the drug can affect enzymes in the digestive tract that promote the digestion and absorption of fats, that is, lipase. A significant advantage of Xenical is its minimal systemic impact. The drug can be taken for a sufficiently long time for patients who have problems with excess weight and high glucose levels. In addition to taking the medication, you will need to follow a low-calorie diet and engage in moderate physical activity.
Take "Xenical" three times a day, one capsule (120 mg) with meals. The duration of treatment and the need to adjust the daily dosage is determined only individually.
Side effects
To frequent side effects, the manufacturer refers to urgent urge to defecate, loose stools, flatulence, abdominal discomfort. To avoid such unpleasant phenomena, it is necessary to limit the consumption of fatty foods. Only 2% of diabetic patients developed a hypoglycemic state. Possible manifestation of an allergy to the active substance in the form of urticaria, itching, redness of the skin. Rarely more serious cases: bronchospasm, angioedema.
Fatty liver and overweight
Fatty hepatosis is a serious pathology of the liver. Most often, the disease affects people who have metabolic disorders, excess weight, bad habits, protein deficiency, hypovitaminosis. Symptoms at the initial stage of the disease usually do not appear, and the patient seeks medical help when the situation is running. The treatment method is selected after laboratory tests, ultrasound of the liver.
To prescribe drug therapy, you should consult a gastroenterologist or hepatologist. The medicine for fatty liver is prescribed in combination with preventive measures. If the cause of the disease is excess weight, it is imperative to adhere to a diet (table number 5), completely eliminate junk food from the diet and engage in physical activity. The danger to the body is a sharp weight loss (more than 700 g per week), which can cause the progression of the pathological process.
Medicated treatment
What medicines for fatty liver will help to cope with the disease? First of all, the patient will be prescribed drugs that normalize the functioning of the organ. Hepatoprotectors have restorative properties - drugs that stimulate the functionality of liver cells and protect it from the negative effects of harmful food, toxins, and certain medications. This category of drugs includes:
- "Heptral".
- Essentiale Forte.
- Essliver.
- Liv-52.
- Karsil.
In the treatment of fatty liver, you will need to lower your cholesterol. Drugs from the statin group will cope with this task: Atoris, Liprimar, Crestor. In addition, you will need to take antioxidants and vitamin complexes.
"Heptral": instructions
Heptral is a French cure for fatty liver. The name of the active substance is ademeteonin. One tablet contains 400 mg. The same dosage of the active ingredient is also available in 5 ml ampoules. The solution lyophilisate is suitable for both intramuscular and intravenous administration to patients.
The drug has a detoxifying, choleretic, hepatoprotective, antioxidant and cholekinetic effect on the body. In addition, the manufacturer claims that the active substance has neuroprotective, antidepressant and antifibrosing properties. The drug is able to enhance the secretion of bile and make up for the lackadenosylmethionine (coenzyme).
The drug is prescribed for fatty hepatosis, chronic hepatitis, liver intoxication, encephalopathy, angiocholitis. Genetic disorders affecting the adenosylmethionine cycle and tearing out homocystinuria or hyperhomocysteinemia are contraindications for the use of Heptral.
Description of the drug "Liv-52"
The medicine for fatty liver "Liv-52" is a hepatoprotector based on herbal ingredients. Chicory seeds, prickly caper roots, yarrow, cassia seeds, tamarix and black nightshade are used as active substances. The listed components are specially steamed from a mixture of other plant extracts.
The drug is available in the form of dark brown tablets and drops for oral use. The combined herbal medicine has a choleretic, hepatoprotective, anti-inflammatory and antioxidant effect. With its help, it is possible to block the development of degenerative and fibrotic changes, activate intracellular metabolic processes and restore hepatocytes.
Indications for the appointment of a herbal medicine are pathologies such as fatty hepatosis, hepatitis of various origins, cirrhosis of the liver. You can also take Liv-52 as a cure for obesity. In pharmacies, the average cost of a medication is 380-450 rubles.
Medication in the form of drops can be prescribed for preventive and therapeutic purposes for children over 2 years old. It is forbidden to use "Liv-52" during pregnancy and lactation,as well as in case of hypersensitivity to the components of the product.
