Antiviral preparation "Ergoferon" is an immunomodulatory homeopathic preparation of a complete type. It has anti-inflammatory, antihistamine, antiviral activity. The price of the drug "Ergoferon" (composition of the drug, analogues are given in the article) corresponds to the level of quality.
Clinical and pharmacological properties
The antiviral drug "Ergoferon" is considered an antihistamine. The medicinal product contains the following active ingredients:
- affinity purified anti-CD4 antibodies (non appropriated);
- affinity purified antibodies to human gamma interferon (non appropriated);
- affinity purified antibodies to histamine (non appropriated).
Composition, release options and packaging of the medicinal product
The antiviral drug "Ergoferon" is available in the form of lozenges. The color of the drug is white (almost white), the shape of the tablet is flat-cylindrical, with a chamfer and a risk. On the side of the flat type withthe words MATERIA MEDICA are fixed with a notch, on the other side with a chamfer is written ERGOFERON.
The active ingredients in one tablet of the medicinal product are contained in the following volumes:
- Affinity Purified Anti-CD4 Antibodies - 0.006 grams.
- Affinity purified antibodies to human gamma interferon - 0.006 grams.
- Affinity purified antibodies to histamine - 0.006 grams.
All of these substances are mixed in the form of three water-alcohol active substantive dilutions. Mixing ratios are as follows: 10012, 10030, 10050 times.
In addition to the main substances, the drug contains auxiliary elements: lactose monohydrate (0.267 g), microcrystalline cellulose (0.03 g), magnesium stearate (0.003 g).
The antiviral agent is available in cardboard packs of various sizes, twenty pieces each. Blisters are available with one, two, five cells in each box.
The action of a drug of a pharmacological type
The antiviral drug "Ergoferon" has a large spectrum of activity of the pharmacological type. It includes immunomodulatory, antiviral, anti-inflammatory and antihistamine action.
Clinically and experimentally proven that the components of this medicinal product are effective for use in the event of viral infections: influenza group A or B, acute respiratory viral infections (caused by adenoviruses, parainfluenza, coronaviruses, virusesrespiratory syncytial type, etc.).
Also, this drug is effective for herpesvirus infections (labial, herpes zoster, genital herpes, ophthalmic herpes, chicken pox, infectious mononucleosis), acute intestinal infections of the viral type (caused by caliciviruses, coronaviruses, rotaviruses, enteroviruses).
In addition to the action of the drug "Ergoferon" in rotovirus and other diseases, the antiviral agent helps with meningococcal and enteroviral meningitis, hemorrhagic fever with renal type syndrome and tick-borne encephalitis.
This drug is widely used in the complex therapeutic fight against bacterial infections (whooping cough, pseudotuberculosis, yersiniosis, pneumonia of various types). Also, the drug is often used to prevent complications of a bacterial type as a consequence of a viral infection and a measure to prevent the development of superinfections.
The drug can be prescribed in the pre-vaccination and post-vaccination period, which significantly increases the degree of vaccination effectiveness, provides non-specific prophylaxis against influenza and SARS during the formation of post-vaccination immunity.
According to the instructions for use, "Ergoferon" for adults and children is used as an effective prophylactic for the treatment of non-influenza type ARVI, to prevent the development of intercurrent diseases in the period after vaccination.
Components that are included in the drugthe drug has a single mechanism of action in the form of an increase in the activity of the functional type of receptors for interferon gamma (IFN γ), CD4 receptors and histamine. All this is accompanied by a pronounced effect of an immunotropic nature.
Experimental methods have shown an increase in the expression of IFN α / β, IFN γ and conjugated interleukins IL-4, IL-2, IL-10 and others) due to the interaction of antibodies and interferon gamma. In addition, this effect improves the interaction of the ligand-receptor type with respect to IFN, restores the status of a cytokine character, normalizes the functionality, activity and concentration of natural-type antibodies to IFN-γ, which are important factors for the development of natural antiviral tolerance in the human body.
In addition, the interaction of the elements that make up the drug stimulates biological interferon-dependent processes (generalized expression of antigens of the main complex of the first and second type of histocompatibility, as well as Fc receptors, activation of monocytes, stimulation of the functional work of NK cells, regulation of immunoglobulin synthesis after activation of mixed Th2 and Th1).
The combined use of all components of the complex type in one drug significantly enhances the antiviral activity of each element of the remedy.
Pharmacokinetic properties
According to the instructions for use, "Ergoferon" (adults and children can take it) has specific pharmacokinetic properties. The features arethe fact that the degree of sensitivity of modern chemical-physical analytical methods (gas-liquid chromatography, high-performance liquid chromatography, gas chromatography-mass spectrometry) does not make it possible to fully assess the content of active components in a medicinal product in tissues, organs and liquids of a biological type.
Due to these problems, it is technically impossible to study the pharmacokinetic properties of the drug.
Indications for use and contraindications
In the instructions for the use of "Ergoferon" (it is often prescribed to adults) it is indicated that the drug is used in the following cases:
- treatment and prevention of influenza group B and A;
- treatment and prevention of diseases associated with acute respiratory viral infections caused by adenovirus, parainfluenza, coronavirus, respiratory syncytial type virus;
- treatment and prevention of herpesvirus-type infections (ophthalmoherpes, labial and genital herpes, chickenpox, infectious mononucleosis, herpes zoster);
- treatment and prevention of intestinal acute infections with viral etymology, which are caused by one of the pathogens (calicivirus, coronavirus, adenovirus, enterovirus, rotavirus);
- treatment and prevention of meningococcal and enteroviral meningitis, hemorrhagic fever with renal syndrome, encephalitis (tick-borne);
- application in complex type therapy,associated with bacterial infections (pseudotuberculosis, whooping cough, yersiniosis, pneumonia with various etiologies, including those caused by atypical pathogens);
- prevention of bacterial-type complications associated with viral infections and prevention of superinfections.
The ban on the use of the drug is one. Contraindications for "Ergoferon" - individual hypersensitivity of the human body to the components of the remedy.
Drug dosage
Having considered what Ergoferon helps with, you should study the features of taking the drug. The drug must be taken orally, separately from meals. To achieve the maximum effect, the tablet should be kept under the tongue (or just lie), do not swallow, so that it completely dissolves.
There are features on how to give "Ergoferon" to children. If babies from six months to three years are prescribed a drug, it must be dissolved in a small amount of water (boiled). It is important that the liquid is at room temperature. Dissolve the tablet in a tablespoon of water.
The drug treatment regimen is as follows. The first day of taking the drug includes the use of eight tablets: one every thirty minutes in the first two hours. The total number of tablets in the first period is five pieces.
According to the testimony of "Ergoferon" after the end of a two-hour interval, in the first twenty-four hours, one tablet is taken every three hours, at equal intervalstime. On the second and subsequent days, the drug is reduced to three tablets per day until a complete cure.
Prophylactic use of the drug
In contrast to the treatment process, there are features of how to drink "Ergoferon" for the prevention of diseases of a viral infectious type. In this case, the number of tablets taken is reduced to one or two per day.
The duration of the course of prevention recommended by doctors is from one month to six months. The specific period of taking the drug is determined on an individual basis.
If necessary, you can use the drug along with other antiviral and symptomatic types.
Side effects, overdose and interactions with other drugs
Having studied in detail what Ergoferon helps with, it is necessary to consider the side effects of the drug.
If an overdose was accidentally made while taking the drug, dyspeptic symptoms may occur due to the fillers that are part of the treatment.
With regard to drug interactions, it should be noted that so far there have been no cases of drug incompatibility with other therapeutic agents.
Separately, it should be noted the compatibility features of "Ergoferon" and alcohol. Reviews of doctors say that taking the medication in question with alcohol togetherNot recommended. Because of this, the patient's body may be harmed, and the effectiveness of the treatment may be reduced to zero.
In this regard, after taking the drug, it is recommended to maintain a twenty-four-hour interval. If the patient has drunk any alcoholic beverage, at least ten to fifteen hours should elapse before taking the medicine.
Special Instructions
Because this medicinal product contains lactose monohydrate, it should not be given to people diagnosed with congenital galactosemia, galactose or glucose malabsorption syndrome, or congenital lactase deficiency.
With regard to influencing the ability to drive vehicles and various mechanisms, it should be noted that the drug "Ergoferon" does not have such negative properties.
It should be noted that the safety of the drug during pregnancy and lactation has not been studied. In this regard, it is necessary to be guided by the rule that the benefit to the mother must exceed the potential harm to the baby.
Terms of sale of funds in pharmacies, storage, reviews
Medicinal drug "Ergoferon" for the treatment of colds is dispensed in pharmacies without a prescription. The shelf life of the medicinal product is not more than three years. Keep the packaging out of the reach of small children, protected from direct sunlight, storage temperature - no more than twenty-five degrees. After the expiration date of the drug has expired, it is prohibited to use it.
Medicinal reviewsmeans in most cases positive. In particular, they note the effectiveness of the drug for children with laryngitis, SARS, tracheitis, etc.
They are especially positive about this therapeutic type drug due to the fact that it does not belong to the group of homeopathic remedies. They also note the convenience of taking the medicine due to the ability to easily reduce the dosage by breaking the tablet in half.
A lot of positive feedback regarding the ability to purchase the drug at any pharmacy without a prescription, as well as the safety of the drug for young children.
Some patients spoke negatively about the remedy, claiming not only its ineffectiveness, but also that the symptoms worsened after taking the drug.
Also on the sites you can find a lot of negative statements regarding the price of the medicine. This is due to the fact that the dosage of the drug requires taking a large number of tablets during the treatment period. Therefore, often one small package is enough for only one course.
Many reviews relate to analogues of "Ergoferon". There are no drugs that are completely identical to the one under consideration in pharmacies. At the same time, pharmacists themselves, attending physicians, patients consider the following drugs as analogues: "Anaferon", "Ocilococcinum", "Viferon", "Kagocel". The degree of effectiveness of each of these drugs is different, but the overall effect is almost the same.
The antiviral drug "Ergoferon" is intended for the treatment andprevention of a wide range of diseases associated with the impact of bacteria on the human body. Achieving the highest efficiency from taking the drug can be achieved with the correct use of tablets and compliance with the dosage and timing of administration. It is best to purchase a large package of the drug.
