Gel "Clodifen" belongs to the group of non-steroidal anti-inflammatory drugs of local action. It is used to eliminate pain in muscles and joints, as well as to relieve tissue edema.
Composition of the drug
The main active ingredient of the drug is diclofenac sodium. As excipients: ethyl alcohol, propylene glycol, nipagin, hydroxyethyl cellulose ether, purified water, carbomer.
Gel "Clodifen" has a colorless or yellowish tint of a uniform consistency. There is a slight smell of ethyl alcohol. It is packaged in 45-gram aluminum tubes. On sale you can find 1% and 5% gel. In addition to the tube, the cardboard box contains instructions for using the Clodifen gel.
General characteristics
The drug has an analgesic and antipyretic effect. It also fights inflammation. Its effect is to suppress the enzymes of cyclooxygenase of the first and second type, inhibition of the metabolism of arachidonic acid and blockbiological synthesis of PG (prostaglandins) at the center of the inflammatory process.
The amount of the active substance is absorbed into the skin evenly over the entire area of the lesion and depends both on the degree of its hydration and on the dose of the drug applied.
After applying the product in the recommended way, about 6% of diclofenac is absorbed. If you create a hermetic isolation of damaged skin with an occlusive dressing for about 9-10 hours, then the absorption will increase several times, but this is not recommended. Metabolic products of the main component are excreted to a large extent with urine. Accumulating in the skin, it gradually penetrates into deeper tissues, where its concentration is 20 times stronger than in blood plasma.
This drug has no effect on the brain, so it is not prohibited when driving a car or work that requires concentrated attention and high speed of psychomotor reactions.
Indications for use
According to the instructions, the Clodifen gel is used for severe symptoms of inflammatory processes in tissues. It effectively eliminates signs of hyperemia and relieves pain.
This drug is intended for the treatment of inflammation, pain or swelling that occurs due to damage to the joints and soft tissues. These can be sprains, trauma to the tendons or ligaments, joint dislocation, hematomas, sports injuries, etc. Soft tissue rheumatism - tendovaginitis, tendinitis, periarthritis, bursitis,osteoarthritis. And also the application is shown at:
- gout;
- systemic lupus;
- osteoarthrosis;
- psoriatic, juvenile and rheumatoid arthritis;
- polymyositis;
- polymyalgia rheumatica;
- Wagner-Unferricht-Hepp disease (dermatomyositis).
Prescribed for edema or pronounced pain associated with diseases of the joints and muscles, such as:
- rheumatoid arthritis;
- sciatica;
- lumbago;
- osteoarthritis;
- sciatica, etc.
Topical use of Clodifen gel helps reduce the use of other oral painkillers and NSAIDs. It quickly relieves pain and relieves swelling. With its help, the activity of the motor apparatus is greatly improved.
Contraindications for use
Of the contraindications to the use of the drug, note:
- hypersensitivity to the constituent components of the product and acetylsalicylic acid;
- individual intolerance to NSAIDs;
- having a history of symptoms of urticaria, rhinitis, or bronchial asthma caused by non-steroidal anti-inflammatory drugs;
- last trimester of pregnancy;
- under the age of 18.
In addition, it is forbidden to apply the gel on damaged skin and open wounds. The drug is prescribed with great care to people who have an ulcer or erosive lesions.gastrointestinal tract, bronchial asthma, heart failure, impaired liver and kidney function, hepatic porphyria.
Dosage and regimen
Depending on the area of the affected area, the amount of the agent used is also determined. For example, if the skin is 600 square cm, then the gel should be used 3g.
1% Clodifen gel is used 3 to 4 times a day, but only for adults or children over 12 years of age.
5% gel is used 2 to 3 times per day, and also only by adults or children over 12 years of age. Procedures should be carried out at regular time intervals. Duration of admission should not exceed 2 weeks. If within 10 days the patient's condition has not improved, you should definitely consult a doctor.
The drug is used only on the affected area. A strip of gel is applied and gently rubbed into the skin with massage movements. Be sure to wash your hands with soap after use. You can do without it only if it is the hands that are sick and they need to be lubricated with gel.
Keep medicine out of the reach of children. When using, avoid contact with eyes and mouth. If accidental penetration into the oral cavity occurs, you should immediately rinse the stomach and take the adsorbent.
Pregnancy and lactation
The drug can only be used in the third trimester of pregnancy. In the first two, the reception is undesirable, but if the benefit to the expectant mother outweighs the potential risk to the baby, thenwith the permission of a doctor, this is possible.
It is also not recommended to use this product during lactation, since the main active ingredient, diclofenac, can pass into breast milk.
Side effects
Side reactions are not excluded. They may appear as itching, burning, flushing, dryness, or contact dermatitis.
Reactions such as:
- urticaria;
- bronchial asthma;
- angioedema;
- bullous dermatitis;
- photosensitivity;
- bronchospasms;
- abdominal pain;
- disorders of the gastrointestinal tract;
- dyspepsia.
Risk of overdose is unlikely.
Interaction with other drugs
Since diclofenac is absorbed in very minimal doses, there is very little interaction with other drugs. However, taking the gel enhances the effect of those drugs that cause photosensitivity.
In addition, the drug is strictly forbidden to be used simultaneously with cosmetic products that are applied locally, similar to a gel.
Analogues of the gel "Clodifen"
To choose an analogue or generic for a certain drug, you need to carefully study the composition of drugs. If the active ingredients are the same, then you have found a pharmaceutical alternative. However, the difference in the composition of additional substances can lead toundesirable negative consequences, so you should definitely consult with your doctor.
Here is an approximate list of analogues of the Clodifen gel (see photo below):
- "Almiral". The drug also has diclofenac as its main active ingredient. It belongs to the group of non-steroidal anti-inflammatory drugs. It is administered as a topical cream, ointment or gel. Indications are inflammatory processes of the musculoskeletal system, muscle tissue injuries and pain in the joints and muscles.
- Voltaren. Belongs to the group of NSAIDs. It relieves pain and inflammation. Has a warming effect at the site of application. Regeneration of cells and tissues after using the gel is much faster.
Of the analogs of the Clodifen gel (in Kazakhstan and Russia), the most suitable, except for Almiral and Voltaren, are:
- Gel "Diclogen". Its active substance is diclofenac diethylamine. Auxiliary ones are: chlorocresol, triethanolamine, propylene glycol, liquid light paraffin, lavender, purified water, etc. It is indicated for use in inflammation after injuries in the joints, tendons, tissues, muscles and ligaments. Contraindicated in children under 12 years of age, with individual intolerance to the components, as well as in the elderly and in heart failure, liver and kidney disorders.
- "Orthoflex". In this preparation, the main components are absolutely identicalgel "Clodifen" substance - diclofenac sodium. And from the additional components emit: imidazolidinyl urea, benzyl benzoate and sodium hydroxide. It is prescribed for periarthropathy, osteoarthritis of the spine and peripheral joints, sprains, dislocations, epicondylitis, fibrositis and myalgia. Contraindications are exactly the same as those of the Clodifen gel.
And you can also buy the gel "Diklak", "Diklomek", "Naklofen" or "Tabiflex".
Patient testimonials
Reviews of the Clodifen gel are mostly positive. Patients using the drug claim that help is provided almost instantly. And the pain can completely disappear in just 3-4 days. This is especially true of injuries sustained while playing sports.
Also, patients are advised not to use bandages in the form of warm scarves or bandages, as you can get a burn or rash. A small number of people who use this remedy have experienced short-term stomach pain.
You have learned everything about the reviews and analogues of the Clodifen gel. Next, we will provide a summary of the prices for this drug.
Prices for the drug in Kazakhstan and Russia
Prices for Clodifen gel range from 1370 tenge (about 240 rubles) to 1540 tenge (270 rubles). The average cost is 1411 tenge (249 rubles).
